dbPTM

KI26B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KI26B_HUMAN
UniProt AC	Q2KJY2
Protein Name	Kinesin-like protein KIF26B
Gene Name	KIF26B
Organism	Homo sapiens (Human).
Sequence Length	2108
Subcellular Localization	Cytoplasm. Cytoplasm, cytoskeleton .
Protein Description	Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity)..
Protein Sequence	MNSVAGNKERLAVSTRGKKYGVNEVCSPTKPAAPFSPESWYRKAYEESRAGSRPTPEGAGSALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGGSPGFGTGSPGSGSGGGSSPGSDRGVWCENCNARLVELKRQALRLLLPGPFPGKDPAFSAVIHDKLQVPNTIRKAWNDRDNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDASPCSPPPLSNIPTLVGSRHVGGLQQPRDWAFVPAPCATSNYTGFANKHGSKPSSLGVSNGAEKKSGSPTHQAKVSLQMATSPSNGNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQISQLMTESSREGLTEAVLNRYNADKPSACSVPASQGSCVASETSTGTSVAASFFARAAQKLNLSSKKKKHRPSTSSAAEPPLFATSFSGILQTSPPPAPPCLLRAVNKVKDTPGLGKVKVMLRICSTLARDTSESSSFLKVDPRKKQITLYDPLTCGGQNAFQKRGNQVPPKMFAFDAVFPQDASQAEVCAGTVAEVIQSVVNGADGCVFCFGHAKLGKSYTMIGKDDSMQNLGIIPCAISWLFKLINERKEKTGARFSVRVSAVEVWGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAAIASRRSHQQDCDEDDHRNSHVFFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALSKNREGGSGLCLSLSALGNVILALVNGSKHIPYKESKLAMLLRESLGNMNCRTTMIAHISAAVGSYAETLSTIQIASRVLRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHTRATVDPDFPIAHLSSDPDYSSSSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTRGDSRPAEAGEAAAGKSERDCLKCNTFAELQERLDCIDGSEEPSSFPFEELPAQFGPEQASRGPRLSQAAGASPLSESDKEDNGSEGQLTNREGPELPASKMQRSHSPVPAAAPAHSPSPASPRSVPGSSSQHSASPLVQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYKPPSSPSQRCKVYTQKGVLPSPAPLPPSSKDSGVASRESLLQPEVRTPPVGMSPQVLKKSMSAGSEGFPETPVDDEQQAATPSESKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISGVLDSGRPTSIISFNSDCSARALASGSRPVSIISSISEDLECYSSTAPVSEVSITQFLPLPKMSLDEKAQDAGSRRSSISSWLSEMSAGSEGEQSCHSFIAQTCFGHGEAMAEPVASEFVSSLQNTAVVCREKPKASPDNLLILSEMGDDSFNKAAPIKGCKISTVSKAMVTISNTANLSSCEGYIPMKTNITVYPCIAMSPRNIQEPEAPTATPKAGPTLAQSRESKENSAKKEMKFEDPWLKREEEVKKETAHPNEEGMMRCETATGPSNAETRAEQEQDGKPSPGDRLSSSSGEVSASPVTDNFRRVVDGCEMALPGLATQSPVHPNKSVKSSSLPRAFQKASRQEEPDSLSYYCAAETNGVGAASGTPPSKATLEGKVASPKHCVLARPKGTPPLPPVRKSSLDQKNRASPQHSASGSGTSSPLNQPAAFPAGLPDEPSGKTKDASSSSKLFSAKLEQLASRSNSLGRATVSHYECLSLERAESLSSVSSRLHAGKDGTMPRAGRSLGRSAGTSPPSSGASPKAGQSKISAVSRLLLASPRARGPSASTTKTLSFSTKSLPQAVGQGSSSPPGGKHTPWSTQSLSRNRSSGLASKLPLRAVSGRISELLQGGAGARGLQLRAGPEAEARGGALAEDEPAAAHLLPSPYSKITPPRRPHRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSSGYESVMRDSEATGSASSAQDSTSENSSSVGGRCRSLKTPKKRSNPGSQRRRLIPALSLDTSSPVRKPPNSTGVRWVDGPLRSSPRGLGEPFEIKVYEIDDVERLQRRRGGASKEAMCFNAKLKILEHRQQRIAEVRAKYEWLMKELEATKQYLMLDPNKWLSEFDLEQVWELDSLEYLEALECVTERLESRVNFCKAHLMMITCFDITSRRR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	VSTRGKKYGVNEVCS EECCCCCCCCCCCCC	29.77	27732954
27	Phosphorylation	YGVNEVCSPTKPAAP CCCCCCCCCCCCCCC	40.56	27732954
29	Phosphorylation	VNEVCSPTKPAAPFS CCCCCCCCCCCCCCC	33.11	27732954
36	Phosphorylation	TKPAAPFSPESWYRK CCCCCCCCHHHHHHH	27.05	27732954
39	Phosphorylation	AAPFSPESWYRKAYE CCCCCHHHHHHHHHH	32.56	27732954
41	Phosphorylation	PFSPESWYRKAYEES CCCHHHHHHHHHHHH	16.12	27732954
257	Phosphorylation	APCATSNYTGFANKH CCCCCCCCCCCCCCC	14.17	-
269	Phosphorylation	NKHGSKPSSLGVSNG CCCCCCCHHHCCCCC	41.76	25627689
270	Phosphorylation	KHGSKPSSLGVSNGA CCCCCCHHHCCCCCC	37.36	25627689
274	Phosphorylation	KPSSLGVSNGAEKKS CCHHHCCCCCCCCCC	27.96	25627689
397	Phosphorylation	AAQKLNLSSKKKKHR HHHHCCCCCCCCCCC	38.75	24719451
398	Phosphorylation	AQKLNLSSKKKKHRP HHHCCCCCCCCCCCC	52.22	-
459	Phosphorylation	KVMLRICSTLARDTS HHHHHHHHHHHCCCC	24.88	21712546
465	Phosphorylation	CSTLARDTSESSSFL HHHHHCCCCCCCCCC	28.92	21712546
468	Phosphorylation	LARDTSESSSFLKVD HHCCCCCCCCCCCCC	30.92	21712546
470	Phosphorylation	RDTSESSSFLKVDPR CCCCCCCCCCCCCCC	43.83	24719451
552	2-Hydroxyisobutyrylation	FGHAKLGKSYTMIGK ECCCCCCCCEEEECC	51.21	-
553	Phosphorylation	GHAKLGKSYTMIGKD CCCCCCCCEEEECCC	24.84	24719451
618	Phosphorylation	LSEVATGSLQDGQSP HHHHHHCCCCCCCCC	20.64	28348404
624	Phosphorylation	GSLQDGQSPGVYLCE CCCCCCCCCCEEEEC	29.20	28348404
688	Phosphorylation	VFFTLHIYQYRMEKS EEEEEEEEEEEHHHC	6.69	-
705	Phosphorylation	GGMSGGRSRLHLIDL CCCCCCCCCEEEEEH	42.33	17081983
727	Phosphorylation	SKNREGGSGLCLSLS HCCCCCCCCEEEHHH	39.17	22210691
752	Phosphorylation	NGSKHIPYKESKLAM CCCCCCCHHHHHHHH	27.13	22210691
755	Phosphorylation	KHIPYKESKLAMLLR CCCCHHHHHHHHHHH	28.90	22210691
764	Phosphorylation	LAMLLRESLGNMNCR HHHHHHHHHCCCCCH	34.83	22210691
785	Phosphorylation	ISAAVGSYAETLSTI HHHHHHHHHHHHHHH	11.52	-
788	Phosphorylation	AVGSYAETLSTIQIA HHHHHHHHHHHHHHH	20.17	22210691
806	Phosphorylation	LRMKKKKTKYTSSSS HHCCCCCCCCCCCCC	37.86	-
808	Phosphorylation	MKKKKTKYTSSSSGG CCCCCCCCCCCCCCC	19.65	-
809	Phosphorylation	KKKKTKYTSSSSGGE CCCCCCCCCCCCCCC	24.56	-
813	Phosphorylation	TKYTSSSSGGESSCE CCCCCCCCCCCCCCC	53.41	-
817	Phosphorylation	SSSSGGESSCEEGRM CCCCCCCCCCCCCCC	43.49	24719451
828	Phosphorylation	EGRMRRPTQLRPFHT CCCCCCCCCCCCCCC	38.12	22817900
881	Phosphorylation	ALSDKELTDNEGPPD CCCCHHHCCCCCCCC	37.56	27732954
903	Phosphorylation	LQKTRGDSRPAEAGE HHHHCCCCCCHHHHH	42.88	22210691
966	Phosphorylation	ASRGPRLSQAAGASP HHCCCCHHHHCCCCC	21.03	25921289
972	Phosphorylation	LSQAAGASPLSESDK HHHHCCCCCCCCCCC	26.00	30108239
975	Phosphorylation	AAGASPLSESDKEDN HCCCCCCCCCCCCCC	38.14	28387310
977	Phosphorylation	GASPLSESDKEDNGS CCCCCCCCCCCCCCC	51.08	26657352
984	Phosphorylation	SDKEDNGSEGQLTNR CCCCCCCCCCCCCCC	44.82	30108239
989	Phosphorylation	NGSEGQLTNREGPEL CCCCCCCCCCCCCCC	25.09	30108239
1004	Phosphorylation	PASKMQRSHSPVPAA CHHHCCCCCCCCCCC	16.07	26657352
1006	Phosphorylation	SKMQRSHSPVPAAAP HHCCCCCCCCCCCCC	28.92	29255136
1016	Phosphorylation	PAAAPAHSPSPASPR CCCCCCCCCCCCCCC	29.22	30108239
1018	Phosphorylation	AAPAHSPSPASPRSV CCCCCCCCCCCCCCC	35.79	27251789
1021	Phosphorylation	AHSPSPASPRSVPGS CCCCCCCCCCCCCCC	24.99	30108239
1024	Phosphorylation	PSPASPRSVPGSSSQ CCCCCCCCCCCCCCC	35.73	27732954
1028	Phosphorylation	SPRSVPGSSSQHSAS CCCCCCCCCCCCCCC	22.27	27732954
1029	Phosphorylation	PRSVPGSSSQHSASP CCCCCCCCCCCCCCC	39.67	27732954
1030	Phosphorylation	RSVPGSSSQHSASPL CCCCCCCCCCCCCCC	33.34	27732954
1033	Phosphorylation	PGSSSQHSASPLVQS CCCCCCCCCCCCCCC	23.86	27732954
1035	Phosphorylation	SSSQHSASPLVQSPS CCCCCCCCCCCCCCC	23.06	27732954
1040	Phosphorylation	SASPLVQSPSLQSSR CCCCCCCCCCHHHHH	14.69	27732954
1042	Phosphorylation	SPLVQSPSLQSSRES CCCCCCCCHHHHHHH	44.26	27732954
1045	Phosphorylation	VQSPSLQSSRESLNS CCCCCHHHHHHHHHC	36.33	27732954
1046	Phosphorylation	QSPSLQSSRESLNSC CCCCHHHHHHHHHCC	27.40	27732954
1052	Phosphorylation	SSRESLNSCGFVEGK HHHHHHHCCCCCCCC	22.40	27251275
1065	Phosphorylation	GKPRPMGSPRLGIAS CCCCCCCCCCCEEEE	10.70	24719451
1072	Phosphorylation	SPRLGIASLSKTSEY CCCCEEEECCCCCCC	31.12	22985185
1074	Phosphorylation	RLGIASLSKTSEYKP CCEEEECCCCCCCCC	31.24	-
1076	Phosphorylation	GIASLSKTSEYKPPS EEEECCCCCCCCCCC	24.34	29083192
1077	Phosphorylation	IASLSKTSEYKPPSS EEECCCCCCCCCCCC	42.54	23312004
1079	Phosphorylation	SLSKTSEYKPPSSPS ECCCCCCCCCCCCHH	28.67	27732954
1083	Phosphorylation	TSEYKPPSSPSQRCK CCCCCCCCCHHHCCE	64.51	28387310
1084	Phosphorylation	SEYKPPSSPSQRCKV CCCCCCCCHHHCCEE	34.05	29900121
1086	Phosphorylation	YKPPSSPSQRCKVYT CCCCCCHHHCCEEEE	32.00	22617229
1111	Phosphorylation	LPPSSKDSGVASRES CCCCCCCCCCCCHHH	38.61	27732954
1115	Phosphorylation	SKDSGVASRESLLQP CCCCCCCCHHHHCCC	33.89	27732954
1118	Phosphorylation	SGVASRESLLQPEVR CCCCCHHHHCCCCCC	33.01	27732954
1126	Phosphorylation	LLQPEVRTPPVGMSP HCCCCCCCCCCCCCH	36.80	25850435
1132	Phosphorylation	RTPPVGMSPQVLKKS CCCCCCCCHHHHHHH	13.27	25850435
1139	Phosphorylation	SPQVLKKSMSAGSEG CHHHHHHHHCCCCCC	19.18	27732954
1141	Phosphorylation	QVLKKSMSAGSEGFP HHHHHHHCCCCCCCC	36.25	27732954
1144	Phosphorylation	KKSMSAGSEGFPETP HHHHCCCCCCCCCCC	33.97	27732954
1150	Phosphorylation	GSEGFPETPVDDEQQ CCCCCCCCCCCHHHH	28.93	27732954
1160	Phosphorylation	DDEQQAATPSESKKE CHHHHCCCCCHHHHH	30.29	25921289
1162	Phosphorylation	EQQAATPSESKKEIL HHHCCCCCHHHHHHH	50.58	27732954
1164	Phosphorylation	QAATPSESKKEILST HCCCCCHHHHHHHHC	54.06	27732954
1170	Phosphorylation	ESKKEILSTTMVTVQ HHHHHHHHCEEEEEE	27.74	-
1171	Phosphorylation	SKKEILSTTMVTVQQ HHHHHHHCEEEEEEC	18.57	-
1212	Phosphorylation	GRPTSIISFNSDCSA CCCCEEEEECCCHHH	19.39	27732954
1215	Phosphorylation	TSIISFNSDCSARAL CEEEEECCCHHHHHH	37.67	27732954
1218	Phosphorylation	ISFNSDCSARALASG EEECCCHHHHHHHCC	26.27	27732954
1267	Methylation	PKMSLDEKAQDAGSR CCCCCCHHHHHHCCC	51.52	116252805
1336	Phosphorylation	CREKPKASPDNLLIL ECCCCCCCCCCEEEE	38.62	27732954
1344	Phosphorylation	PDNLLILSEMGDDSF CCCEEEEEECCCCCC	20.67	27732954
1350	Phosphorylation	LSEMGDDSFNKAAPI EEECCCCCCCCCCCC	35.14	27732954
1371	Phosphorylation	TVSKAMVTISNTANL EEEEEEEEEECCCCC	12.95	24114839
1373	Phosphorylation	SKAMVTISNTANLSS EEEEEEEECCCCCCC	20.82	24114839
1375	Phosphorylation	AMVTISNTANLSSCE EEEEEECCCCCCCCC	15.33	24114839
1432	Acetylation	ESKENSAKKEMKFED HHHHHHHHHHHCCCC	49.43	7668649
1452	Phosphorylation	EEEVKKETAHPNEEG HHHHHHHCCCCCCCC	38.86	-
1465	Phosphorylation	EGMMRCETATGPSNA CCCCEEEECCCCCCH	32.90	-
1467	Phosphorylation	MMRCETATGPSNAET CCEEEECCCCCCHHH	57.98	-
1470	Phosphorylation	CETATGPSNAETRAE EEECCCCCCHHHHHH	50.44	-
1474	Phosphorylation	TGPSNAETRAEQEQD CCCCCHHHHHHHHHC	32.54	-
1485	Phosphorylation	QEQDGKPSPGDRLSS HHHCCCCCCCCCCCC	45.03	30177828
1491	Phosphorylation	PSPGDRLSSSSGEVS CCCCCCCCCCCCEEC	29.12	27732954
1492	Phosphorylation	SPGDRLSSSSGEVSA CCCCCCCCCCCEECC	32.87	27732954
1493	Phosphorylation	PGDRLSSSSGEVSAS CCCCCCCCCCEECCC	38.70	27732954
1494	Phosphorylation	GDRLSSSSGEVSASP CCCCCCCCCEECCCC	40.70	27732954
1498	Phosphorylation	SSSSGEVSASPVTDN CCCCCEECCCCCCCC	20.80	29255136
1500	Phosphorylation	SSGEVSASPVTDNFR CCCEECCCCCCCCHH	16.64	29255136
1503	Phosphorylation	EVSASPVTDNFRRVV EECCCCCCCCHHHHC	28.71	29255136
1522	Phosphorylation	MALPGLATQSPVHPN CCCCCCCCCCCCCCC	34.32	27732954
1524	Phosphorylation	LPGLATQSPVHPNKS CCCCCCCCCCCCCCC	25.24	27732954
1534	Phosphorylation	HPNKSVKSSSLPRAF CCCCCCCCCCCCHHH	24.01	26699800
1535	Phosphorylation	PNKSVKSSSLPRAFQ CCCCCCCCCCCHHHH	30.12	26699800
1536	Phosphorylation	NKSVKSSSLPRAFQK CCCCCCCCCCHHHHH	49.86	24719451
1583	Phosphorylation	TLEGKVASPKHCVLA CCCCEECCCCCEEEE	37.15	-
1613	Phosphorylation	LDQKNRASPQHSASG CCCCCCCCCCCCCCC	23.12	24117733
1617	Phosphorylation	NRASPQHSASGSGTS CCCCCCCCCCCCCCC	20.91	24117733
1619	Phosphorylation	ASPQHSASGSGTSSP CCCCCCCCCCCCCCC	36.18	24117733
1621	Phosphorylation	PQHSASGSGTSSPLN CCCCCCCCCCCCCCC	36.08	24117733
1623	Phosphorylation	HSASGSGTSSPLNQP CCCCCCCCCCCCCCC	27.94	24117733
1624	Phosphorylation	SASGSGTSSPLNQPA CCCCCCCCCCCCCCC	33.22	24117733
1625	Phosphorylation	ASGSGTSSPLNQPAA CCCCCCCCCCCCCCC	32.99	24117733
1642	Phosphorylation	AGLPDEPSGKTKDAS CCCCCCCCCCCCCCC	51.37	23312004
1677	Phosphorylation	GRATVSHYECLSLER CCHHCCHHHHHCHHH	10.79	25884760
1681	Phosphorylation	VSHYECLSLERAESL CCHHHHHCHHHHHHH	39.58	25850435
1687	Phosphorylation	LSLERAESLSSVSSR HCHHHHHHHHHHHHH	32.35	29255136
1689	Phosphorylation	LERAESLSSVSSRLH HHHHHHHHHHHHHHC	37.66	29255136
1690	Phosphorylation	ERAESLSSVSSRLHA HHHHHHHHHHHHHCC	31.17	29255136
1692	Phosphorylation	AESLSSVSSRLHAGK HHHHHHHHHHHCCCC	16.22	29255136
1693	Phosphorylation	ESLSSVSSRLHAGKD HHHHHHHHHHCCCCC	36.38	29255136
1702	Phosphorylation	LHAGKDGTMPRAGRS HCCCCCCCCCCCCHH	33.85	27251275
1713	Phosphorylation	AGRSLGRSAGTSPPS CCHHCCCCCCCCCCC	29.29	27732954
1716	Phosphorylation	SLGRSAGTSPPSSGA HCCCCCCCCCCCCCC	37.46	27732954
1717	Phosphorylation	LGRSAGTSPPSSGAS CCCCCCCCCCCCCCC	33.62	27732954
1720	Phosphorylation	SAGTSPPSSGASPKA CCCCCCCCCCCCCCC	44.80	27732954
1721	Phosphorylation	AGTSPPSSGASPKAG CCCCCCCCCCCCCCC	44.12	27732954
1724	Phosphorylation	SPPSSGASPKAGQSK CCCCCCCCCCCCHHH	30.38	27732954
1730	Phosphorylation	ASPKAGQSKISAVSR CCCCCCHHHHHHHHH	30.92	24719451
1742	Phosphorylation	VSRLLLASPRARGPS HHHHHHHCCCCCCCC	18.19	28387310
1752	Phosphorylation	ARGPSASTTKTLSFS CCCCCCCCCCEECEE	31.84	-
1757	Phosphorylation	ASTTKTLSFSTKSLP CCCCCEECEECCCCC	23.53	23312004
1759	Phosphorylation	TTKTLSFSTKSLPQA CCCEECEECCCCCCC	31.39	22617229
1762	Phosphorylation	TLSFSTKSLPQAVGQ EECEECCCCCCCCCC	45.42	29255136
1771	Phosphorylation	PQAVGQGSSSPPGGK CCCCCCCCCCCCCCC	21.54	29255136
1772	Phosphorylation	QAVGQGSSSPPGGKH CCCCCCCCCCCCCCC	54.40	29255136
1773	Phosphorylation	AVGQGSSSPPGGKHT CCCCCCCCCCCCCCC	36.49	30108239
1780	Phosphorylation	SPPGGKHTPWSTQSL CCCCCCCCCCCHHHC	29.91	24117733
1783	Phosphorylation	GGKHTPWSTQSLSRN CCCCCCCCHHHCCCC	20.13	24117733
1784	Phosphorylation	GKHTPWSTQSLSRNR CCCCCCCHHHCCCCC	20.50	24117733
1786	Phosphorylation	HTPWSTQSLSRNRSS CCCCCHHHCCCCCCC	28.53	24117733
1788	Phosphorylation	PWSTQSLSRNRSSGL CCCHHHCCCCCCCCH	32.53	24117733
1792	Phosphorylation	QSLSRNRSSGLASKL HHCCCCCCCCHHHHC	32.10	21712546
1793	Phosphorylation	SLSRNRSSGLASKLP HCCCCCCCCHHHHCC	34.29	21712546
1797	Phosphorylation	NRSSGLASKLPLRAV CCCCCHHHHCCHHHH	39.50	21712546
1809	Phosphorylation	RAVSGRISELLQGGA HHHHHHHHHHHHCCC	22.34	27251275
1851	Phosphorylation	AHLLPSPYSKITPPR HHCCCCCCCCCCCCC	27.25	25884760
1855	Phosphorylation	PSPYSKITPPRRPHR CCCCCCCCCCCCCCC	30.86	24719451
1890	Phosphorylation	MGKTALFYHSGGSSG CCCEEEEEECCCCCH	8.91	24114839
1892	Phosphorylation	KTALFYHSGGSSGYE CEEEEEECCCCCHHH	33.21	24114839
1895	Phosphorylation	LFYHSGGSSGYESVM EEEECCCCCHHHHHC	24.90	24114839
1896	Phosphorylation	FYHSGGSSGYESVMR EEECCCCCHHHHHCC	48.98	24114839
1898	Phosphorylation	HSGGSSGYESVMRDS ECCCCCHHHHHCCCC	13.64	25884760
1908	Phosphorylation	VMRDSEATGSASSAQ HCCCCCCCCCCCCCC	27.84	-
1923	Phosphorylation	DSTSENSSSVGGRCR CCCCCCCCCCCCCHH	40.39	-
1943	Phosphorylation	KKRSNPGSQRRRLIP CCCCCCCHHHHCEEE	23.05	23612710
1953	Phosphorylation	RRLIPALSLDTSSPV HCEEECEECCCCCCC	26.72	28387310
1956	Phosphorylation	IPALSLDTSSPVRKP EECEECCCCCCCCCC	36.08	27732954
1957	Phosphorylation	PALSLDTSSPVRKPP ECEECCCCCCCCCCC	32.10	27732954
1958	Phosphorylation	ALSLDTSSPVRKPPN CEECCCCCCCCCCCC	29.52	28387310
1978	Phosphorylation	WVDGPLRSSPRGLGE CCCCCCCCCCCCCCC	52.99	17081983
1979	Phosphorylation	VDGPLRSSPRGLGEP CCCCCCCCCCCCCCC	16.51	26699800
1992	Phosphorylation	EPFEIKVYEIDDVER CCCEEEEEEECHHHH	11.36	25884760
2017	Acetylation	EAMCFNAKLKILEHR HHHHHHHHHHHHHHH	51.95	7709715
2019	Acetylation	MCFNAKLKILEHRQQ HHHHHHHHHHHHHHH	44.53	7709727
2035	Phosphorylation	IAEVRAKYEWLMKEL HHHHHHHHHHHHHHH	16.02	29083192
2045	Phosphorylation	LMKELEATKQYLMLD HHHHHHHHHHHHCCC	14.87	29083192
2086	Phosphorylation	CVTERLESRVNFCKA HHHHHHHHHHHHHHH	46.23	22817900
2104	Phosphorylation	MITCFDITSRRR--- HHHHEEHHHCCC---	20.30	30631047
2105	Phosphorylation	ITCFDITSRRR---- HHHEEHHHCCC----	24.91	30631047

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	NEDD4	P46934	PMID:22768111

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
1855	T	Phosphorylation	-
Phosphorylation at Thr-1855 and Ser-1958 by CDKs, mainly CDK2 and CDK5, enhances the interaction with NEDD4, polyubiquitination, and subsequent proteasomal degradation.
1855	T	ubiquitylation	-
Phosphorylation at Thr-1855 and Ser-1958 by CDKs, mainly CDK2 and CDK5, enhances the interaction with NEDD4, polyubiquitination, and subsequent proteasomal degradation.
1958	S	Phosphorylation	-
Phosphorylation at Thr-1855 and Ser-1958 by CDKs, mainly CDK2 and CDK5, enhances the interaction with NEDD4, polyubiquitination, and subsequent proteasomal degradation.
1958	S	ubiquitylation	-
Phosphorylation at Thr-1855 and Ser-1958 by CDKs, mainly CDK2 and CDK5, enhances the interaction with NEDD4, polyubiquitination, and subsequent proteasomal degradation.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KI26B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NEDD4_HUMAN	NEDD4	physical	22768111
DLG1_HUMAN	DLG1	physical	26496610
CSKP_HUMAN	CASK	physical	26496610
ZC3HD_HUMAN	ZC3H13	physical	26496610
ANKL2_HUMAN	ANKLE2	physical	26496610
WBP11_HUMAN	WBP11	physical	26496610
LIN7C_HUMAN	LIN7C	physical	26496610
HAKAI_HUMAN	CBLL1	physical	26496610
MPP7_HUMAN	MPP7	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KI26B_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2086, AND MASSSPECTROMETRY.	17081983 [Abstract]

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