dbPTM

SLTM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SLTM_HUMAN
UniProt AC	Q9NWH9
Protein Name	SAFB-like transcription modulator
Gene Name	SLTM
Organism	Homo sapiens (Human).
Sequence Length	1034
Subcellular Localization	Nucleus. Detected in punctate structures..
Protein Description	When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis..
Protein Sequence	MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAATGAVA ------CCCHHHHHH	19.67	22814378
5	Phosphorylation	---MAAATGAVAASA ---CCCHHHHHHHHH	22.43	20068231
11	Phosphorylation	ATGAVAASAASGQAE HHHHHHHHHHCCCCC	18.03	19691289
14	Phosphorylation	AVAASAASGQAEGKK HHHHHHHCCCCCCCC	31.02	19691289
20	2-Hydroxyisobutyrylation	ASGQAEGKKITDLRV HCCCCCCCCCCCEEE	32.29	-
23	Phosphorylation	QAEGKKITDLRVIDL CCCCCCCCCEEEEEC	37.55	23532336
31	2-Hydroxyisobutyrylation	DLRVIDLKSELKRRN CEEEEECCHHHHHCC	37.83	-
31	Acetylation	DLRVIDLKSELKRRN CEEEEECCHHHHHCC	37.83	25953088
31	Malonylation	DLRVIDLKSELKRRN CEEEEECCHHHHHCC	37.83	26320211
32	Phosphorylation	LRVIDLKSELKRRNL EEEEECCHHHHHCCC	56.30	28555341
42	Phosphorylation	KRRNLDITGVKTVLI HHCCCCCCCHHHHHH	35.27	20068231
69	Phosphorylation	DPDNIELTVSTDTPN CCCCEEEEEECCCCC	10.30	22167270
71	Phosphorylation	DNIELTVSTDTPNKK CCEEEEEECCCCCCC	18.48	22167270
72	Phosphorylation	NIELTVSTDTPNKKP CEEEEEECCCCCCCC	39.29	22167270
74	Phosphorylation	ELTVSTDTPNKKPTK EEEEECCCCCCCCCC	28.93	22167270
80	Phosphorylation	DTPNKKPTKGKGKKH CCCCCCCCCCCCCCC	62.40	22167270
93	Phosphorylation	KHEADELSGDASVED CCCHHHCCCCCCCCC	32.36	30266825
97	Phosphorylation	DELSGDASVEDDAFI HHCCCCCCCCCCCEE	30.68	30266825
126	Phosphorylation	GNDELKDSEEFGENE CCCHHCCHHHHCCCH	37.12	25849741
139	Phosphorylation	NEEENVHSKELLSAE CHHCCCCHHHHHCHH	24.44	20873877
140	Ubiquitination	EEENVHSKELLSAEE HHCCCCHHHHHCHHH	37.19	-
144	Phosphorylation	VHSKELLSAEENKRA CCHHHHHCHHHHHHH	46.38	23401153
149	2-Hydroxyisobutyrylation	LLSAEENKRAHELIE HHCHHHHHHHHHHHH	55.00	-
149	Acetylation	LLSAEENKRAHELIE HHCHHHHHHHHHHHH	55.00	25953088
170	Phosphorylation	IEKEDIESQEIEAQE HHHHHHHCCCEECCC	33.19	20164059
182	Phosphorylation	AQEGEDDTFLTAQDG CCCCCCCCEEECCCC	32.63	27251275
185	Phosphorylation	GEDDTFLTAQDGEEE CCCCCEEECCCCCCH	20.34	21406692
199	Phosphorylation	EENEKDIAGSGDGTQ HHCCCCCCCCCCCCC	19.07	27251275
201	Phosphorylation	NEKDIAGSGDGTQEV CCCCCCCCCCCCCEE	25.37	25849741
205	Phosphorylation	IAGSGDGTQEVSKPL CCCCCCCCCEECCCC	26.71	29255136
209	Phosphorylation	GDGTQEVSKPLPSEG CCCCCEECCCCCCCC	28.01	29255136
214	Phosphorylation	EVSKPLPSEGSLAEA EECCCCCCCCCCCCC	63.37	29255136
217	Phosphorylation	KPLPSEGSLAEADHT CCCCCCCCCCCCCCH	21.98	29255136
224	Phosphorylation	SLAEADHTAHEEMEA CCCCCCCHHHHHHHH	30.20	29255136
233	Phosphorylation	HEEMEAHTTVKEAED HHHHHHHEEHHHCCC	40.09	27251275
234	Phosphorylation	EEMEAHTTVKEAEDD HHHHHHEEHHHCCCC	21.51	29255136
244	O-linked_Glycosylation	EAEDDNISVTIQAED HCCCCCEEEEEEECC	21.33	30379171
244	Phosphorylation	EAEDDNISVTIQAED HCCCCCEEEEEEECC	21.33	19007248
254	Phosphorylation	IQAEDAITLDFDGDD EEECCCEEECCCCHH	23.23	18452278
265	Phosphorylation	DGDDLLETGKNVKIT CCHHHHHCCCCEECC	54.12	26074081
270	Acetylation	LETGKNVKITDSEAS HHCCCCEECCCCCCC	49.64	25953088
272	Phosphorylation	TGKNVKITDSEASKP CCCCEECCCCCCCCC	27.96	23927012
274	Phosphorylation	KNVKITDSEASKPKD CCEECCCCCCCCCCC	26.81	23927012
277	Phosphorylation	KITDSEASKPKDGQD ECCCCCCCCCCCCCC	45.50	23401153
289	Phosphorylation	GQDAIAQSPEKESKD CCCHHHCCCCHHHHH	26.46	19664994
294	Phosphorylation	AQSPEKESKDYEMNA HCCCCHHHHHCCCCC	41.73	30278072
297	Phosphorylation	PEKESKDYEMNANHK CCHHHHHCCCCCCCC	22.33	23401153
307	Acetylation	NANHKDGKKEDCVKG CCCCCCCCHHHCCCC	64.22	26051181
308	Acetylation	ANHKDGKKEDCVKGD CCCCCCCHHHCCCCC	65.40	7710551
330	Phosphorylation	ESSKKAESGDKEKDT HHHHHCCCCCCCCCC	58.09	24719451
343	Phosphorylation	DTLKKGPSSTGASGQ CCHHCCCCCCCCCCC	49.56	28176443
344	Phosphorylation	TLKKGPSSTGASGQA CHHCCCCCCCCCCCC	33.71	28176443
345	Phosphorylation	LKKGPSSTGASGQAK HHCCCCCCCCCCCCC	40.90	29691806
348	Phosphorylation	GPSSTGASGQAKSSS CCCCCCCCCCCCCCC	32.55	29691806
353	Phosphorylation	GASGQAKSSSKESKD CCCCCCCCCCCCCCC	42.74	24905233
354	Phosphorylation	ASGQAKSSSKESKDS CCCCCCCCCCCCCCC	44.73	24905233
355	Phosphorylation	SGQAKSSSKESKDSK CCCCCCCCCCCCCCC	47.75	28176443
356	Acetylation	GQAKSSSKESKDSKT CCCCCCCCCCCCCCC	68.87	11922869
363	Phosphorylation	KESKDSKTSSKDDKG CCCCCCCCCCCCCCC	42.03	30576142
371	Phosphorylation	SSKDDKGSTSSTSGS CCCCCCCCCCCCCCC	30.75	28985074
372	Acetylation	SKDDKGSTSSTSGSS CCCCCCCCCCCCCCC	35.05	-
372	Phosphorylation	SKDDKGSTSSTSGSS CCCCCCCCCCCCCCC	35.05	28176443
373	Phosphorylation	KDDKGSTSSTSGSSG CCCCCCCCCCCCCCC	33.06	26074081
374	Phosphorylation	DDKGSTSSTSGSSGS CCCCCCCCCCCCCCC	27.04	28985074
375	Phosphorylation	DKGSTSSTSGSSGSS CCCCCCCCCCCCCCC	36.55	30576142
376	Phosphorylation	KGSTSSTSGSSGSST CCCCCCCCCCCCCCC	38.33	28176443
378	Phosphorylation	STSSTSGSSGSSTKN CCCCCCCCCCCCCCC	31.15	28176443
379	Phosphorylation	TSSTSGSSGSSTKNI CCCCCCCCCCCCCCE	46.34	30576142
381	Phosphorylation	STSGSSGSSTKNIWV CCCCCCCCCCCCEEE	36.46	30576142
382	Phosphorylation	TSGSSGSSTKNIWVS CCCCCCCCCCCEEEE	47.10	26074081
383	Acetylation	SGSSGSSTKNIWVSG CCCCCCCCCCEEEEC	29.79	19608861
383	Phosphorylation	SGSSGSSTKNIWVSG CCCCCCCCCCEEEEC	29.79	28176443
388	Acetylation	SSTKNIWVSGLSSNT CCCCCEEEECCCCCC	2.62	19608861
389	O-linked_Glycosylation	STKNIWVSGLSSNTK CCCCEEEECCCCCCC	21.01	30379171
389	Phosphorylation	STKNIWVSGLSSNTK CCCCEEEECCCCCCC	21.01	26074081
392	O-linked_Glycosylation	NIWVSGLSSNTKAAD CEEEECCCCCCCHHH	25.68	30379171
393	Phosphorylation	IWVSGLSSNTKAADL EEEECCCCCCCHHHH	54.27	25627689
395	Phosphorylation	VSGLSSNTKAADLKN EECCCCCCCHHHHHH	24.82	30576142
401	Acetylation	NTKAADLKNLFGKYG CCCHHHHHHHHHHHC	52.75	19608861
401	Malonylation	NTKAADLKNLFGKYG CCCHHHHHHHHHHHC	52.75	26320211
406	2-Hydroxyisobutyrylation	DLKNLFGKYGKVLSA HHHHHHHHHCCEEEE	43.42	-
406	Acetylation	DLKNLFGKYGKVLSA HHHHHHHHHCCEEEE	43.42	19608861
414	Acetylation	YGKVLSAKVVTNARS HCCEEEEEEEECCCC	33.58	25953088
414	Ubiquitination	YGKVLSAKVVTNARS HCCEEEEEEEECCCC	33.58	-
417	Phosphorylation	VLSAKVVTNARSPGA EEEEEEEECCCCCCC	26.58	21955146
421	Phosphorylation	KVVTNARSPGAKCYG EEEECCCCCCCEEEE	25.85	28355574
427	Phosphorylation	RSPGAKCYGIVTMSS CCCCCEEEEEEEECC	14.80	26074081
433	Phosphorylation	CYGIVTMSSSTEVSR EEEEEEECCCHHHHH	16.27	20068231
434	Phosphorylation	YGIVTMSSSTEVSRC EEEEEECCCHHHHHH	30.38	20068231
435	Phosphorylation	GIVTMSSSTEVSRCI EEEEECCCHHHHHHH	22.68	20068231
436	Phosphorylation	IVTMSSSTEVSRCIA EEEECCCHHHHHHHH	42.21	20068231
439	Phosphorylation	MSSSTEVSRCIAHLH ECCCHHHHHHHHHHH	18.40	20068231
459	Acetylation	GQLISVEKVKGDPSK CEEEEEEECCCCCCH	47.28	26051181
477	Phosphorylation	KKENDEKSSSRSSGD HHHCCCCCCCCCCCC	31.34	22817900
482	Phosphorylation	EKSSSRSSGDKKNTS CCCCCCCCCCCCCCC	50.31	22817900
488	Phosphorylation	SSGDKKNTSDRSSKT CCCCCCCCCCCCHHH	40.67	23312004
489	Phosphorylation	SGDKKNTSDRSSKTQ CCCCCCCCCCCHHHH	40.18	23312004
492	Phosphorylation	KKNTSDRSSKTQASV CCCCCCCCHHHHHHH	40.97	23312004
493	Phosphorylation	KNTSDRSSKTQASVK CCCCCCCHHHHHHHH	40.39	23312004
495	Phosphorylation	TSDRSSKTQASVKKE CCCCCHHHHHHHHHH	31.17	23312004
500	Sumoylation	SKTQASVKKEEKRSS HHHHHHHHHHHHHCH	52.55	-
500	Sumoylation	SKTQASVKKEEKRSS HHHHHHHHHHHHHCH	52.55	28112733
506	Phosphorylation	VKKEEKRSSEKSEKK HHHHHHHCHHHHHHH	54.65	30576142
510	Phosphorylation	EKRSSEKSEKKESKD HHHCHHHHHHHHCCC	51.07	22468782
515	Phosphorylation	EKSEKKESKDTKKIE HHHHHHHCCCCCCCC	44.72	22817900
518	Phosphorylation	EKKESKDTKKIEGKD HHHHCCCCCCCCCCC	37.66	29457462
533	Phosphorylation	EKNDNGASGQTSESI CCCCCCCCCCCHHHH	32.60	29255136
536	Phosphorylation	DNGASGQTSESIKKS CCCCCCCCHHHHHHH	37.68	29255136
537	Phosphorylation	NGASGQTSESIKKSE CCCCCCCHHHHHHHH	22.81	29255136
539	Phosphorylation	ASGQTSESIKKSEEK CCCCCHHHHHHHHHH	39.20	29255136
543	Phosphorylation	TSESIKKSEEKKRIS CHHHHHHHHHHHCCC	46.08	23401153
550	Phosphorylation	SEEKKRISSKSPGHM HHHHHCCCCCCCCCE	35.43	29255136
551	Phosphorylation	EEKKRISSKSPGHMV HHHHCCCCCCCCCEE	34.48	29255136
552	Acetylation	EKKRISSKSPGHMVI HHHCCCCCCCCCEEE	54.61	25953088
553	Phosphorylation	KKRISSKSPGHMVIL HHCCCCCCCCCEEEE	37.75	29255136
563	Phosphorylation	HMVILDQTKGDHCRP CEEEECCCCCCCCCC	36.34	23927012
576	Phosphorylation	RPSRRGRYEKIHGRS CCCCCCCCHHHCCCC	25.13	28152594
583	Phosphorylation	YEKIHGRSKEKERAS CHHHCCCCHHHHHHC	50.16	28152594
590	Phosphorylation	SKEKERASLDKKRDK CHHHHHHCCHHHCCH	43.24	30266825
593	Acetylation	KERASLDKKRDKDYR HHHHCCHHHCCHHHH	55.81	-
602	Ubiquitination	RDKDYRRKEILPFEK CCHHHHHHHCCCHHH	39.86	-
609	Ubiquitination	KEILPFEKMKEQRLR HHCCCHHHHHHHHHH	56.50	-
718	Phosphorylation	RQQQQLRYEQEKRNS HHHHHHHHHHHHHHC	30.47	26699800
725	Phosphorylation	YEQEKRNSLKRPRDV HHHHHHHCCCCCCCC	39.02	-
740	Phosphorylation	DHRRDDPYWSENKKL CCCCCCCCCCCCCCC	28.67	-
742	Phosphorylation	RRDDPYWSENKKLSL CCCCCCCCCCCCCCC	26.00	21815630
746	Ubiquitination	PYWSENKKLSLDTDA CCCCCCCCCCCCCCC	55.69	-
748	Phosphorylation	WSENKKLSLDTDARF CCCCCCCCCCCCCCC	32.83	30266825
751	Phosphorylation	NKKLSLDTDARFGHG CCCCCCCCCCCCCCC	36.53	19691289
759	Phosphorylation	DARFGHGSDYSRQQN CCCCCCCCCCHHHHC	27.92	27732954
761	Phosphorylation	RFGHGSDYSRQQNRF CCCCCCCCHHHHCCC	13.88	27732954
762	Phosphorylation	FGHGSDYSRQQNRFN CCCCCCCHHHHCCCC	28.71	27732954
782	Phosphorylation	ERGRFPESSAVQSSS HCCCCCCCCCCCCCC	24.68	20068231
783	Phosphorylation	RGRFPESSAVQSSSF CCCCCCCCCCCCCCH	30.69	27732954
787	Phosphorylation	PESSAVQSSSFERRD CCCCCCCCCCHHHHH	22.73	28450419
788	Phosphorylation	ESSAVQSSSFERRDR CCCCCCCCCHHHHHC	23.19	28450419
789	Phosphorylation	SSAVQSSSFERRDRF CCCCCCCCHHHHHCC	36.05	23401153
800	Phosphorylation	RDRFVGQSEGKKARP HHCCCCCCCCCCCCC	42.25	25159151
803	Acetylation	FVGQSEGKKARPTAR CCCCCCCCCCCCCCC	38.93	23749302
815	Phosphorylation	TARREDPSFERYPKN CCCCCCCCHHHCCCC	52.65	29255136
819	Phosphorylation	EDPSFERYPKNFSDS CCCCHHHCCCCCCCC	16.03	27251275
826	Phosphorylation	YPKNFSDSRRNEPPP CCCCCCCCCCCCCCC	31.76	28555341
841	Phosphorylation	PRNELRESDRREVRG CCHHCCHHHHHHHCC	29.95	28555341
855	Phosphorylation	GERDERRTVIIHDRP CCCHHCCEEEEECCC	23.44	29255136
861	Methylation	RTVIIHDRPDITHPR CEEEEECCCCCCCCC	19.34	115917141
865	Phosphorylation	IHDRPDITHPRHPRE EECCCCCCCCCCCCC	32.96	24719451
878	Phosphorylation	REAGPNPSRPTSWKS CCCCCCCCCCCCCCC	58.49	28555341
881	Phosphorylation	GPNPSRPTSWKSEGS CCCCCCCCCCCCCCC	46.22	27794612
882	Phosphorylation	PNPSRPTSWKSEGSM CCCCCCCCCCCCCCC	34.88	27794612
884	Sumoylation	PSRPTSWKSEGSMST CCCCCCCCCCCCCCC	38.09	28112733
885	Phosphorylation	SRPTSWKSEGSMSTD CCCCCCCCCCCCCCC	40.71	28985074
888	Phosphorylation	TSWKSEGSMSTDKRE CCCCCCCCCCCCCCC	12.90	28985074
890	Phosphorylation	WKSEGSMSTDKRETR CCCCCCCCCCCCCCC	34.84	29449344
891	Phosphorylation	KSEGSMSTDKRETRV CCCCCCCCCCCCCCC	36.58	29396449
904	Phosphorylation	RVERPERSGREVSGH CCCCCCCCCCCCCCC	40.31	30576142
909	Phosphorylation	ERSGREVSGHSVRGA CCCCCCCCCCCCCCC	26.49	27794612
912	Phosphorylation	GREVSGHSVRGAPPG CCCCCCCCCCCCCCC	19.62	29691806
914	Methylation	EVSGHSVRGAPPGNR CCCCCCCCCCCCCCC	38.27	81453707
922	Phosphorylation	GAPPGNRSSASGYGS CCCCCCCCCCCCCCC	33.97	23403867
923	Phosphorylation	APPGNRSSASGYGSR CCCCCCCCCCCCCCC	24.18	25849741
925	Phosphorylation	PGNRSSASGYGSREG CCCCCCCCCCCCCCC	34.20	23403867
927	Phosphorylation	NRSSASGYGSREGDR CCCCCCCCCCCCCCC	14.94	23403867
929	Phosphorylation	SSASGYGSREGDRGV CCCCCCCCCCCCCEE	20.76	25849741
938	Phosphorylation	EGDRGVITDRGGGSQ CCCCEEEECCCCCCC	19.76	29214152
940	Methylation	DRGVITDRGGGSQHY CCEEEECCCCCCCCC	36.69	115917145
944	Phosphorylation	ITDRGGGSQHYPEER EECCCCCCCCCHHHH	19.63	25849741
947	Phosphorylation	RGGGSQHYPEERHVV CCCCCCCCHHHHCCH	12.52	28985074
961	Phosphorylation	VERHGRDTSGPRKEW HHHCCCCCCCCCCCC	33.93	24719451
962	Phosphorylation	ERHGRDTSGPRKEWH HHCCCCCCCCCCCCC	51.60	27422710
973	Phosphorylation	KEWHGPPSQGPSYHD CCCCCCCCCCCCCCC	51.40	30108239
977	Phosphorylation	GPPSQGPSYHDTRRM CCCCCCCCCCCCCCC	41.76	27080861
978	Phosphorylation	PPSQGPSYHDTRRMG CCCCCCCCCCCCCCC	13.57	27080861
988	Methylation	TRRMGDGRAGAGMIT CCCCCCCCCCCCCEE	34.29	115917149
993	Sulfoxidation	DGRAGAGMITQHSSN CCCCCCCCEECCCCC	2.73	21406390
995	Phosphorylation	RAGAGMITQHSSNAS CCCCCCEECCCCCCC	16.01	30266825
998	Phosphorylation	AGMITQHSSNASPIN CCCEECCCCCCCCCC	18.57	30266825
999	Phosphorylation	GMITQHSSNASPINR CCEECCCCCCCCCCC	34.00	23401153
1002	Phosphorylation	TQHSSNASPINRIVQ ECCCCCCCCCCCEEE	30.48	22167270
1006	Acetylation	SNASPINRIVQISGN CCCCCCCCEEEECCC	31.04	19608861
1011	Phosphorylation	INRIVQISGNSMPRG CCCEEEECCCCCCCC	18.16	30266825
1014	Phosphorylation	IVQISGNSMPRGSGS EEEECCCCCCCCCCC	33.42	29255136
1015	Sulfoxidation	VQISGNSMPRGSGSG EEECCCCCCCCCCCC	2.81	21406390
1017	Methylation	ISGNSMPRGSGSGFK ECCCCCCCCCCCCCC	43.18	24129315
1019	Phosphorylation	GNSMPRGSGSGFKPF CCCCCCCCCCCCCCC	30.94	25159151
1021	Phosphorylation	SMPRGSGSGFKPFKG CCCCCCCCCCCCCCC	42.63	25159151
1024	Acetylation	RGSGSGFKPFKGGPP CCCCCCCCCCCCCCC	53.74	19608861
1024	Malonylation	RGSGSGFKPFKGGPP CCCCCCCCCCCCCCC	53.74	32601280
1024	Sumoylation	RGSGSGFKPFKGGPP CCCCCCCCCCCCCCC	53.74	28112733
1027	Acetylation	GSGFKPFKGGPPRRF CCCCCCCCCCCCCCC	72.05	25953088
1027	Methylation	GSGFKPFKGGPPRRF CCCCCCCCCCCCCCC	72.05	30585211
1027	Sumoylation	GSGFKPFKGGPPRRF CCCCCCCCCCCCCCC	72.05	28112733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
748	S	Phosphorylation	Kinase	CHEK1	O14757	GPS
815	S	Phosphorylation	Kinase	CHEK1	O14757	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SLTM_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SLTM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ZCCHV_HUMAN	ZC3HAV1	physical	22939629
TIM14_HUMAN	DNAJC19	physical	22939629

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SLTM_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-289, AND MASS SPECTROMETRY.	19413330 [Abstract]
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-401; LYS-406 AND LYS-1024,AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1002 AND SER-1014, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289; SER-550; SER-553AND SER-748, AND MASS SPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-289, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289; SER-550; SER-551;SER-553; SER-1002 AND SER-1014, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-74; SER-289; SER-553 ANDSER-1002, AND MASS SPECTROMETRY.	18691976 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1002, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-244 AND SER-289, ANDMASS SPECTROMETRY.	19007248 [Abstract]
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289, AND MASSSPECTROMETRY.	17287340 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289, AND MASSSPECTROMETRY.	16565220 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289, AND MASSSPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-93; SER-97; SER-289;SER-421; SER-551; SER-553; SER-590 AND SER-1002, AND MASSSPECTROMETRY.	17081983 [Abstract]