dbPTM

BAZ1A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BAZ1A_HUMAN
UniProt AC	Q9NRL2
Protein Name	Bromodomain adjacent to zinc finger domain protein 1A
Gene Name	BAZ1A
Organism	Homo sapiens (Human).
Sequence Length	1556
Subcellular Localization	Nucleus. May target the CHRAC complex to heterochromatin.
Protein Description	Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.; Component of the histone-fold protein complex CHRAC complex which facilitates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions..
Protein Sequence	MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGKKKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPRPSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Ubiquitination	RKPFVRQKPPADLRP CCCCCCCCCCCCCCC	42.26	29967540
61	Ubiquitination	CAVTGRPGLTYQEAL HHHCCCCCCCHHHHH	29.32	21890473
66	Ubiquitination	RPGLTYQEALESEKK CCCCCHHHHHHHHHH	44.82	22817900
72	Ubiquitination	QEALESEKKARQNLQ HHHHHHHHHHHHHHH	62.10	29967540
73	Ubiquitination	EALESEKKARQNLQS HHHHHHHHHHHHHHH	44.76	-
89	Ubiquitination	PEPLIIPVLYLTSLT CCCCHHHHHHHHHCC	3.75	22505724
93	Ubiquitination	IIPVLYLTSLTHRSR HHHHHHHHHCCCHHH	14.24	21890473
98	Ubiquitination	YLTSLTHRSRLHEIC HHHHCCCHHHHHHHH	20.45	21890473
100	Ubiquitination	TSLTHRSRLHEICDD HHCCCHHHHHHHHHH	39.77	22817900
111	Phosphorylation	ICDDIFAYVKDRYFV HHHHHHHHHCCCCCE	9.40	28985074
113	Ubiquitination	DDIFAYVKDRYFVEE HHHHHHHCCCCCEEH	24.66	-
121	Ubiquitination	DRYFVEETVEVIRNN CCCCEEHHHHHHHHC	14.41	22505724
181	Ubiquitination	CSFQNGKKKDAIDPL CCCCCCCCCCCCCHH	58.23	-
182	Ubiquitination	SFQNGKKKDAIDPLL CCCCCCCCCCCCHHH	56.74	-
191	Sumoylation	AIDPLLFKYKVQPTK CCCHHHHHCCCCCCC	44.10	-
191	Ubiquitination	AIDPLLFKYKVQPTK CCCHHHHHCCCCCCC	44.10	21890473
191 (in isoform 1)	Ubiquitination	-	44.10	21890473
191 (in isoform 2)	Ubiquitination	-	44.10	21890473
193	Ubiquitination	DPLLFKYKVQPTKKE CHHHHHCCCCCCCHH	34.68	22817900
199	Ubiquitination	YKVQPTKKELHESAI CCCCCCCHHHHHHHH	68.90	29967540
208	Ubiquitination	LHESAIVKATQISRR HHHHHHHHHHHHHHC	39.33	29967540
225	Acetylation	LFSRDKLKLFLKQHC CCCHHHHHHHHHHHC	42.82	25953088
229	Acetylation	DKLKLFLKQHCEPQD HHHHHHHHHHCCCCC	30.57	26051181
229	Ubiquitination	DKLKLFLKQHCEPQD HHHHHHHHHHCCCCC	30.57	29967540
240	Ubiquitination	EPQDGVIKIKASSLS CCCCCEEEEEECCCC	35.43	29967540
242	Ubiquitination	QDGVIKIKASSLSTY CCCEEEEEECCCCCE	36.89	29967540
266	Phosphorylation	FFPDDPPTFIFSPAN CCCCCCCCEECCCCC	34.45	24732914
270	Phosphorylation	DPPTFIFSPANRRRG CCCCEECCCCCCCCC	20.49	25159151
270 (in isoform 2)	Phosphorylation	-	20.49	-
286	Phosphorylation	PPKRIHISQEDNVAN CCCCEECCCCCCCCC	17.23	28102081
286 (in isoform 2)	Phosphorylation	-	17.23	-
292	Ubiquitination	ISQEDNVANKQTLAS CCCCCCCCCHHHHHH	24.61	22817900
294	Acetylation	QEDNVANKQTLASYR CCCCCCCHHHHHHHH	34.62	25953088
294	Ubiquitination	QEDNVANKQTLASYR CCCCCCCHHHHHHHH	34.62	21890473
313	Sumoylation	KERDKLLKQEEMKSL HHHHHHHHHHHHHHH	67.13	-
313	Sumoylation	KERDKLLKQEEMKSL HHHHHHHHHHHHHHH	67.13	-
318	Acetylation	LLKQEEMKSLAFEKA HHHHHHHHHHHHHHH	45.67	25953088
318	Ubiquitination	LLKQEEMKSLAFEKA HHHHHHHHHHHHHHH	45.67	29967540
324	Ubiquitination	MKSLAFEKAKLKREK HHHHHHHHHHHHHHH	44.35	29967540
326	Ubiquitination	SLAFEKAKLKREKAD HHHHHHHHHHHHHHH	66.66	-
331	Ubiquitination	KAKLKREKADALEAK HHHHHHHHHHHHHHH	56.45	-
339	Ubiquitination	ADALEAKKKEKEDKE HHHHHHHHHHHHHHH	73.53	-
342	Acetylation	LEAKKKEKEDKEKKR HHHHHHHHHHHHHHH	78.91	21339330
345	Acetylation	KKKEKEDKEKKREEL HHHHHHHHHHHHHHH	72.95	21339330
347	Acetylation	KEKEDKEKKREELKK HHHHHHHHHHHHHHH	63.97	21339330
348	Acetylation	EKEDKEKKREELKKI HHHHHHHHHHHHHHH	67.16	21339330
385	Ubiquitination	REKLREEKRKYVEYL HHHHHHHHHHHHHHH	49.81	22817900
387	Ubiquitination	KLREEKRKYVEYLKQ HHHHHHHHHHHHHHH	65.79	22817900
387 (in isoform 1)	Ubiquitination	-	65.79	21890473
387 (in isoform 2)	Ubiquitination	-	65.79	21890473
414	Phosphorylation	LKELPEPTPVKTRLP HHCCCCCCCCCCCCC	38.77	21815630
477	Ubiquitination	LCELLFFFLTAIFQA HHHHHHHHHHHHHHH	4.67	21890473
482	Ubiquitination	FFFLTAIFQAIAEEE HHHHHHHHHHHHHHH	3.58	22817900
503	Ubiquitination	QLTDADTKDLTEALD HCCCCCHHHHHHHHH	51.81	29967540
505	Ubiquitination	TDADTKDLTEALDED CCCCHHHHHHHHHCC	5.06	22505724
508	Ubiquitination	DTKDLTEALDEDADP CHHHHHHHHHCCCCC	18.32	29967540
538	Ubiquitination	PQLHQGCSLKSLDLD HHHHCCCCCCCCCCC	45.73	21890473
538 (in isoform 2)	Ubiquitination	-	45.73	21890473
540	Ubiquitination	LHQGCSLKSLDLDSC HHCCCCCCCCCCCCC	32.45	-
543	Ubiquitination	GCSLKSLDLDSCTLS CCCCCCCCCCCCCHH	56.36	22817900
547	Glutathionylation	KSLDLDSCTLSEILR CCCCCCCCCHHHHHH	4.42	22555962
560	Phosphorylation	LRLHILASGADVTSA HHHHHHHCCCCCCCC	30.94	23898821
565	Phosphorylation	LASGADVTSANAKYR HHCCCCCCCCCHHHH	23.75	23898821
566	Ubiquitination	ASGADVTSANAKYRY HCCCCCCCCCHHHHC	21.26	22505724
567	Ubiquitination	SGADVTSANAKYRYQ CCCCCCCCCHHHHCH	15.61	29967540
570	Acetylation	DVTSANAKYRYQKRG CCCCCCHHHHCHHCC	30.02	25953088
570	Ubiquitination	DVTSANAKYRYQKRG CCCCCCHHHHCHHCC	30.02	22817900
570 (in isoform 1)	Ubiquitination	-	30.02	21890473
575	Ubiquitination	NAKYRYQKRGGFDAT CHHHHCHHCCCCCCC	44.04	22817900
576	Methylation	AKYRYQKRGGFDATD HHHHCHHCCCCCCCC	34.64	-
587	Sulfoxidation	DATDDACMELRLSNP CCCCHHHHHHHCCCH	6.11	21406390
588	Ubiquitination	ATDDACMELRLSNPS CCCHHHHHHHCCCHH	30.53	24816145
595	Phosphorylation	ELRLSNPSLVKKLSS HHHCCCHHHHHHHCC	50.47	25159151
598	Acetylation	LSNPSLVKKLSSTSV CCCHHHHHHHCCCCC	53.97	25953088
598	Ubiquitination	LSNPSLVKKLSSTSV CCCHHHHHHHCCCCC	53.97	22505724
599	Ubiquitination	SNPSLVKKLSSTSVY CCHHHHHHHCCCCCC	46.23	29967540
601	Phosphorylation	PSLVKKLSSTSVYDL HHHHHHHCCCCCCCC	40.21	30622161
602	Phosphorylation	SLVKKLSSTSVYDLT HHHHHHCCCCCCCCC	34.83	30622161
603	Phosphorylation	LVKKLSSTSVYDLTP HHHHHCCCCCCCCCC	20.88	30622161
604	Phosphorylation	VKKLSSTSVYDLTPG HHHHCCCCCCCCCCH	22.19	30622161
606	Phosphorylation	KLSSTSVYDLTPGEK HHCCCCCCCCCCHHH	12.66	22817900
620	Ubiquitination	KMKILHALCGKLLTL HHHHHHHHHHHHHHH	2.49	24816145
637	Phosphorylation	TRDFIEDYVDILRQA HHHHHHHHHHHHHHH	6.29	27642862
652	Ubiquitination	KQEFRELKAEQHRKE HHHHHHHHHHHHHHH	45.16	29967540
698	Phosphorylation	EDEQRNSTADISIGE HHHHHHCCCCCCCCH	31.72	29449344
699 (in isoform 2)	Phosphorylation	-	16.38	-
702	Phosphorylation	RNSTADISIGEEERE HHCCCCCCCCHHHHH	25.70	27362937
713	Phosphorylation	EEREDFDTSIESKDT HHHHHCCCCCCCCCH	31.43	26471730
714	Phosphorylation	EREDFDTSIESKDTE HHHHCCCCCCCCCHH	26.63	21815630
717	Phosphorylation	DFDTSIESKDTEQKE HCCCCCCCCCHHCHH	33.87	26471730
720	Phosphorylation	TSIESKDTEQKELDQ CCCCCCCHHCHHHHH	44.01	23927012
731	Phosphorylation	ELDQDMVTEDEDDPG HHHHHCCCCCCCCCC	30.95	29255136
739	Phosphorylation	EDEDDPGSHKRGRRG CCCCCCCCCCCCCCC	31.09	23403867
747	Ubiquitination	HKRGRRGKRGQNGFK CCCCCCCCCCCCCHH	52.09	29967540
754	Acetylation	KRGQNGFKEFTRQEQ CCCCCCHHHCHHHHH	54.00	25953088
766	Phosphorylation	QEQINCVTREPLTAD HHHCCCCCCCCCCCC	31.36	23312004
771	Phosphorylation	CVTREPLTADEEEAL CCCCCCCCCCHHHHH	42.66	29978859
779	Ubiquitination	ADEEEALKQEHQRKE CCHHHHHHHHHHHHH	61.77	29967540
808	Ubiquitination	NIFPLGRDRMYRRYW CCCCCCCCCCCHHHC	37.59	24816145
818 (in isoform 2)	Phosphorylation	-	23.40	-
840	Ubiquitination	TEDMLLPRPSSFQNN CCCCCCCCCHHHCCC	43.64	24816145
842	Phosphorylation	DMLLPRPSSFQNNVQ CCCCCCCHHHCCCCC	45.09	23322592
850	Phosphorylation	SFQNNVQSQDPQVST HHCCCCCCCCCCCCC	32.06	23663014
852	Ubiquitination	QNNVQSQDPQVSTKT CCCCCCCCCCCCCCC	40.63	29967540
856	Phosphorylation	QSQDPQVSTKTGEPL CCCCCCCCCCCCCCC	20.95	23322592
856	Ubiquitination	QSQDPQVSTKTGEPL CCCCCCCCCCCCCCC	20.95	29967540
857	Phosphorylation	SQDPQVSTKTGEPLM CCCCCCCCCCCCCCC	33.49	23322592
859	Phosphorylation	DPQVSTKTGEPLMSE CCCCCCCCCCCCCCC	47.03	23312004
864	Sulfoxidation	TKTGEPLMSESTSNI CCCCCCCCCCCCCCC	6.46	21406390
865	Phosphorylation	KTGEPLMSESTSNID CCCCCCCCCCCCCCC	35.76	23312004
867	Phosphorylation	GEPLMSESTSNIDQG CCCCCCCCCCCCCCC	29.81	23312004
868	Phosphorylation	EPLMSESTSNIDQGP CCCCCCCCCCCCCCC	23.03	23312004
869	Phosphorylation	PLMSESTSNIDQGPR CCCCCCCCCCCCCCC	40.86	23312004
874	Ubiquitination	STSNIDQGPRDHSVQ CCCCCCCCCCCCCCC	18.57	24816145
884	Ubiquitination	DHSVQLPKPVHKPNR CCCCCCCCCCCCCCC	69.16	29967540
887	Ubiquitination	VQLPKPVHKPNRWCF CCCCCCCCCCCCEEE	48.67	29967540
888	Ubiquitination	QLPKPVHKPNRWCFY CCCCCCCCCCCEEEC	44.19	29967540
894	Ubiquitination	HKPNRWCFYSSCEQL CCCCCEEECCCHHHH	5.42	29967540
906	Ubiquitination	EQLDQLIEALNSRGH HHHHHHHHHHHHCCC	56.55	24816145
914	Ubiquitination	ALNSRGHRESALKET HHHHCCCHHHHHHHH	42.25	29967540
919	Acetylation	GHRESALKETLLQEK CCHHHHHHHHHHHHH	48.66	7851397
919	Ubiquitination	GHRESALKETLLQEK CCHHHHHHHHHHHHH	48.66	29967540
920	Ubiquitination	HRESALKETLLQEKS CHHHHHHHHHHHHHH	45.60	29967540
926	Acetylation	KETLLQEKSRICAQL HHHHHHHHHHHHHHH	31.88	26051181
926	Ubiquitination	KETLLQEKSRICAQL HHHHHHHHHHHHHHH	31.88	29967540
946	Ubiquitination	EKFHFSDKPQPDSKP HHCCCCCCCCCCCCC	44.33	29967540
952	Acetylation	DKPQPDSKPTYSRGR CCCCCCCCCCCCCCC	49.08	25953088
952	Sumoylation	DKPQPDSKPTYSRGR CCCCCCCCCCCCCCC	49.08	28112733
952	Ubiquitination	DKPQPDSKPTYSRGR CCCCCCCCCCCCCCC	49.08	29967540
956	Phosphorylation	PDSKPTYSRGRSSNA CCCCCCCCCCCCCCC	30.64	25627689
960	Phosphorylation	PTYSRGRSSNAYDPS CCCCCCCCCCCCCHH	30.67	25159151
961	Phosphorylation	TYSRGRSSNAYDPSQ CCCCCCCCCCCCHHH	24.90	25159151
964	Phosphorylation	RGRSSNAYDPSQMCA CCCCCCCCCHHHHHH	32.41	28985074
967	Phosphorylation	SSNAYDPSQMCAEKQ CCCCCCHHHHHHHHH	27.87	26552605
973	Acetylation	PSQMCAEKQLELRLR HHHHHHHHHHHHHHH	41.48	23749302
973	Ubiquitination	PSQMCAEKQLELRLR HHHHHHHHHHHHHHH	41.48	-
991	Phosphorylation	LDIEDRIYQGTLGAI HHHHHHHHCCCCCCE	11.20	28152594
991	Ubiquitination	LDIEDRIYQGTLGAI HHHHHHHHCCCCCCE	11.20	29967540
997	Ubiquitination	IYQGTLGAIKVTDRH HHCCCCCCEEEECHH	11.09	29967540
999	Ubiquitination	QGTLGAIKVTDRHIW CCCCCCEEEECHHHH	38.25	-
1004	Ubiquitination	AIKVTDRHIWRSALE CEEEECHHHHHHHHH	27.12	24816145
1015	Phosphorylation	SALESGRYELLSEEN HHHHHCCCEECCHHH	17.91	25099161
1019	Phosphorylation	SGRYELLSEENKENG HCCCEECCHHHHHCC	56.33	25599653
1023	Ubiquitination	ELLSEENKENGIIKT EECCHHHHHCCCEEE	56.70	29967540
1029	Ubiquitination	NKENGIIKTVNEDVE HHHCCCEEECCCCHH	44.49	29967540
1038	Sulfoxidation	VNEDVEEMEIDEQTK CCCCHHHCCCCCCCE	3.28	21406390
1057	Phosphorylation	DRLLGIKTETPSTVS EECCCCEECCCCCCC	43.07	21406692
1059	Phosphorylation	LLGIKTETPSTVSTN CCCCEECCCCCCCCC	27.98	21406692
1061	Phosphorylation	GIKTETPSTVSTNAS CCEECCCCCCCCCCC	49.19	21406692
1062	Phosphorylation	IKTETPSTVSTNAST CEECCCCCCCCCCCC	21.49	21406692
1064	Phosphorylation	TETPSTVSTNASTPQ ECCCCCCCCCCCCCC	18.94	26074081
1065	Phosphorylation	ETPSTVSTNASTPQS CCCCCCCCCCCCCCH	30.39	26074081
1065	Ubiquitination	ETPSTVSTNASTPQS CCCCCCCCCCCCCCH	30.39	33845483
1068	Phosphorylation	STVSTNASTPQSVSS CCCCCCCCCCCHHHH	42.56	26074081
1069	Phosphorylation	TVSTNASTPQSVSSV CCCCCCCCCCHHHHH	23.96	26074081
1072	Phosphorylation	TNASTPQSVSSVVHY CCCCCCCHHHHHHHH	25.77	26074081
1074	Phosphorylation	ASTPQSVSSVVHYLA CCCCCHHHHHHHHHH	23.74	26074081
1075	Phosphorylation	STPQSVSSVVHYLAM CCCCHHHHHHHHHHH	26.46	26074081
1079	Phosphorylation	SVSSVVHYLAMALFQ HHHHHHHHHHHHHHH	5.64	21406692
1097	Methylation	GIERRFLKAPLDASD HHHHHHCCCCCCCCC	45.29	-
1097	Ubiquitination	GIERRFLKAPLDASD HHHHHHCCCCCCCCC	45.29	24816145
1156	Ubiquitination	ARCKICRKKGDAENM HHCHHHCCCCCCCCE	57.61	-
1157	Ubiquitination	RCKICRKKGDAENMV HCHHHCCCCCCCCEE	42.54	-
1205	Phosphorylation	KQRSRRLSSRQRPSL HHHHHCCCCCCCCCC	22.97	22817900
1206	Phosphorylation	QRSRRLSSRQRPSLE HHHHCCCCCCCCCCC	36.70	17081983
1224	Ubiquitination	DVEDSMGGEDDEVDG CCHHHCCCCCCCCCC	26.90	24816145
1247 (in isoform 2)	Phosphorylation	-	65.65	-
1248 (in isoform 2)	Phosphorylation	-	48.03	-
1249 (in isoform 2)	Phosphorylation	-	64.51	-
1251 (in isoform 2)	Phosphorylation	-	50.61	-
1252	Phosphorylation	VEQDEDDSQEEEEVS CCCCCCCCCHHHHCC	52.38	-
1277	Acetylation	LPVKTRGKLSSSFSS CCCCCCCCCCCCCCC	41.74	23749302
1279	Phosphorylation	VKTRGKLSSSFSSRG CCCCCCCCCCCCCCC	27.67	30266825
1280	Phosphorylation	KTRGKLSSSFSSRGQ CCCCCCCCCCCCCCC	45.93	30266825
1281	Phosphorylation	TRGKLSSSFSSRGQQ CCCCCCCCCCCCCCC	26.27	23401153
1283	Phosphorylation	GKLSSSFSSRGQQQE CCCCCCCCCCCCCCC	22.52	30266825
1284	Phosphorylation	KLSSSFSSRGQQQEP CCCCCCCCCCCCCCC	38.12	22167270
1285	Methylation	LSSSFSSRGQQQEPG CCCCCCCCCCCCCCC	45.82	-
1285	Ubiquitination	LSSSFSSRGQQQEPG CCCCCCCCCCCCCCC	45.82	24816145
1288 (in isoform 2)	Phosphorylation	-	53.05	-
1290	Ubiquitination	SSRGQQQEPGRYPSR CCCCCCCCCCCCCCC	45.44	24816145
1294	Phosphorylation	QQQEPGRYPSRSQQS CCCCCCCCCCCCCCC	16.10	28152594
1294 (in isoform 2)	Phosphorylation	-	16.10	-
1296	Phosphorylation	QEPGRYPSRSQQSTP CCCCCCCCCCCCCCC	35.31	28152594
1298	Phosphorylation	PGRYPSRSQQSTPKT CCCCCCCCCCCCCCC	36.59	28152594
1301	Phosphorylation	YPSRSQQSTPKTTVS CCCCCCCCCCCCEEC	38.75	28152594
1302	Phosphorylation	PSRSQQSTPKTTVSS CCCCCCCCCCCEECC	25.19	28152594
1307 (in isoform 2)	Phosphorylation	-	8.02	-
1308	Phosphorylation	STPKTTVSSKTGRSL CCCCCEECCCCCCCH	24.83	27251275
1309	Phosphorylation	TPKTTVSSKTGRSLR CCCCEECCCCCCCHH	29.87	27251275
1310	Acetylation	PKTTVSSKTGRSLRK CCCEECCCCCCCHHH	47.71	25953088
1311	Phosphorylation	KTTVSSKTGRSLRKI CCEECCCCCCCHHHH	39.51	27251275
1317	Ubiquitination	KTGRSLRKINSAPPT CCCCCHHHHCCCCCC	52.08	24816145
1320	Phosphorylation	RSLRKINSAPPTETK CCHHHHCCCCCCCCC	45.70	30266825
1321 (in isoform 2)	Phosphorylation	-	15.03	-
1324	Phosphorylation	KINSAPPTETKSLRI HHCCCCCCCCCCEEE	56.05	30266825
1326	Phosphorylation	NSAPPTETKSLRIAS CCCCCCCCCCEEEEC	28.54	30266825
1327	Sumoylation	SAPPTETKSLRIASR CCCCCCCCCEEEECC	41.06	-
1327	Acetylation	SAPPTETKSLRIASR CCCCCCCCCEEEECC	41.06	23749302
1327	Sumoylation	SAPPTETKSLRIASR CCCCCCCCCEEEECC	41.06	-
1328	Phosphorylation	APPTETKSLRIASRS CCCCCCCCEEEECCC	30.24	20068231
1331 (in isoform 2)	Phosphorylation	-	5.04	-
1335	Phosphorylation	SLRIASRSTRHSHGP CEEEECCCCCCCCCC	27.57	24719451
1335 (in isoform 2)	Phosphorylation	-	27.57	-
1336	Phosphorylation	LRIASRSTRHSHGPL EEEECCCCCCCCCCC	31.15	23898821
1339	Phosphorylation	ASRSTRHSHGPLQAD ECCCCCCCCCCCCCH	27.18	26055452
1339 (in isoform 2)	Phosphorylation	-	27.18	-
1351	Ubiquitination	QADVFVELLSPRRKR CCHHHHHHHCHHHHH	4.89	24816145
1353	Phosphorylation	DVFVELLSPRRKRRG HHHHHHHCHHHHHCC	29.05	26055452
1362	Ubiquitination	RRKRRGRKSANNTPE HHHHCCCCCCCCCCC	57.66	-
1363	Phosphorylation	RKRRGRKSANNTPEN HHHCCCCCCCCCCCC	34.56	23401153
1364	Ubiquitination	KRRGRKSANNTPENS HHCCCCCCCCCCCCC	19.14	29967540
1366 (in isoform 2)	Phosphorylation	-	57.64	-
1367	Phosphorylation	GRKSANNTPENSPNF CCCCCCCCCCCCCCC	31.61	23401153
1370 (in isoform 2)	Phosphorylation	-	65.06	-
1371	Phosphorylation	ANNTPENSPNFPNFR CCCCCCCCCCCCCCE	21.40	25159151
1372 (in isoform 2)	Phosphorylation	-	59.05	-
1373	Ubiquitination	NTPENSPNFPNFRVI CCCCCCCCCCCCEEE	65.90	29967540
1381 (in isoform 2)	Phosphorylation	-	13.20	-
1382	Phosphorylation	PNFRVIATKSSEQSR CCCEEEEECCCHHHH	21.97	21712546
1383	Acetylation	NFRVIATKSSEQSRS CCEEEEECCCHHHHH	42.85	25953088
1383	Ubiquitination	NFRVIATKSSEQSRS CCEEEEECCCHHHHH	42.85	24816145
1384	Phosphorylation	FRVIATKSSEQSRSV CEEEEECCCHHHHHH	34.45	27732954
1385	Phosphorylation	RVIATKSSEQSRSVN EEEEECCCHHHHHHC	41.01	33259812
1385 (in isoform 2)	Phosphorylation	-	41.01	-
1388	Phosphorylation	ATKSSEQSRSVNIAS EECCCHHHHHHCHHH	23.59	26425664
1388 (in isoform 2)	Phosphorylation	-	23.59	-
1390	Phosphorylation	KSSEQSRSVNIASKL CCCHHHHHHCHHHHH	25.43	29396449
1395	Phosphorylation	SRSVNIASKLSLQES HHHHCHHHHHCCCHH	30.27	21712546
1396	Acetylation	RSVNIASKLSLQESE HHHCHHHHHCCCHHH	32.83	23749302
1396	Ubiquitination	RSVNIASKLSLQESE HHHCHHHHHCCCHHH	32.83	29967540
1398	Phosphorylation	VNIASKLSLQESESK HCHHHHHCCCHHHHH	31.57	19691289
1402	Phosphorylation	SKLSLQESESKRRCR HHHCCCHHHHHHHHH	33.92	25159151
1404	Phosphorylation	LSLQESESKRRCRKR HCCCHHHHHHHHHHC	40.52	28102081
1405	Ubiquitination	SLQESESKRRCRKRQ CCCHHHHHHHHHHCC	39.55	29967540
1413	Phosphorylation	RRCRKRQSPEPSPVT HHHHHCCCCCCCCCC	34.95	29255136
1417	Phosphorylation	KRQSPEPSPVTLGRR HCCCCCCCCCCCCCC	30.27	23927012
1420	Phosphorylation	SPEPSPVTLGRRSSG CCCCCCCCCCCCCCC	27.21	30266825
1424	Ubiquitination	SPVTLGRRSSGRQGG CCCCCCCCCCCCCCC	33.12	32015554
1425	Phosphorylation	PVTLGRRSSGRQGGV CCCCCCCCCCCCCCC	35.47	23898821
1426	Phosphorylation	VTLGRRSSGRQGGVH CCCCCCCCCCCCCCC	35.86	23898821
1428	Ubiquitination	LGRRSSGRQGGVHEL CCCCCCCCCCCCCHH	33.64	29967540
1439	Ubiquitination	VHELSAFEQLVVELV CCHHHHHHHHHHHHH	42.60	29967540
1440	Ubiquitination	HELSAFEQLVVELVR CHHHHHHHHHHHHHH	32.86	29967540
1456	Ubiquitination	DDSWPFLKLVSKIQV CCCCHHHHHHHCCCC	47.42	32015554
1460	Ubiquitination	PFLKLVSKIQVPDYY HHHHHHHCCCCCCHH	29.67	29967540
1467	Phosphorylation	KIQVPDYYDIIKKPI CCCCCCHHHHHCCHH	14.19	-
1471	Acetylation	PDYYDIIKKPIALNI CCHHHHHCCHHHHHH	53.48	178226065
1471	Ubiquitination	PDYYDIIKKPIALNI CCHHHHHCCHHHHHH	53.48	29967540
1472	Ubiquitination	DYYDIIKKPIALNII CHHHHHCCHHHHHHH	31.11	29967540
1492	Phosphorylation	KCEYKLASEFIDDIE HCCHHHHHHHHHHHH	43.40	20860994
1503	Phosphorylation	DDIELMFSNCFEYNP HHHHHHHCCCCCCCC	20.80	20860994
1515	Phosphorylation	YNPRNTSEAKAGTRL CCCCCCCCCCHHHHE	52.75	32142685
1515 (in isoform 2)	Phosphorylation	-	52.75	-
1517	Ubiquitination	PRNTSEAKAGTRLQA CCCCCCCCHHHHEEE	43.21	-
1538	Phosphorylation	QKLGLHVTPSNVDQV HHCCCEECCCCCCCC	15.39	25159151
1540	Phosphorylation	LGLHVTPSNVDQVST CCCEECCCCCCCCCC	39.87	24732914
1546	Phosphorylation	PSNVDQVSTPPAAKK CCCCCCCCCCCHHHH	29.57	23401153
1547	Phosphorylation	SNVDQVSTPPAAKKS CCCCCCCCCCHHHHC	34.14	22167270
1552	Acetylation	VSTPPAAKKSRI--- CCCCCHHHHCCC---	54.08	25953088
1553	Ubiquitination	STPPAAKKSRI---- CCCCHHHHCCC----	39.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1320	S	Phosphorylation	Kinase	CHEK1	O14757	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BAZ1A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BAZ1A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAZ1B_HUMAN	BAZ1B	physical	11980720
SMCA5_HUMAN	SMARCA5	physical	11980720
SMCA5_HUMAN	SMARCA5	physical	12374985
SATB1_HUMAN	SATB1	physical	12374985
SMCA2_HUMAN	SMARCA2	physical	16877760
CHRC1_HUMAN	CHRAC1	physical	14759371
DPOE3_HUMAN	POLE3	physical	14759371
RBBP4_HUMAN	RBBP4	physical	22939629
SMCA5_HUMAN	SMARCA5	physical	25533843
H2AX_HUMAN	H2AFX	physical	25533843
H31_HUMAN	HIST1H3A	physical	25533843
H2B1B_HUMAN	HIST1H2BB	physical	25533843

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BAZ1A_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-270; SER-702 ANDTHR-731, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1402, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1339; SER-1353;SER-1363; THR-1367; SER-1371; SER-1402; SER-1413; SER-1417 ANDTHR-1547, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1413, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1279 AND SER-1281, ANDMASS SPECTROMETRY.	19007248 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1413 AND SER-1417, ANDMASS SPECTROMETRY.	17081983 [Abstract]
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-606, AND MASSSPECTROMETRY.	18083107 [Abstract]