SC31B_HUMAN - dbPTM
SC31B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SC31B_HUMAN
UniProt AC Q9NQW1
Protein Name Protein transport protein Sec31B
Gene Name SEC31B
Organism Homo sapiens (Human).
Sequence Length 1179
Subcellular Localization Cytoplasm . Cytoplasmic vesicle, COPII-coated vesicle membrane
Peripheral membrane protein
Cytoplasmic side . Endoplasmic reticulum membrane
Peripheral membrane protein .
Protein Description As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum..
Protein Sequence MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHRGVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSKGQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHLVPQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
54PhosphorylationEVDFRDPSLDLKHRG
EEECCCCCCCCCHHH		38.51-
64PhosphorylationLKHRGVLSALSRFHK
CCHHHHHHHHHHHHH		25.4325072903
67PhosphorylationRGVLSALSRFHKLVW
HHHHHHHHHHHHHHH		32.3925072903
175PhosphorylationPEDIKALSWNRQAQH
HHHHHHHHHHHHHHH		27.45-
206UbiquitinationRKNEPIIKVSDHSNR
CCCCCEEEECCCCCC		36.0832015554
292PhosphorylationILCRNLGSSEVVYKL
EEECCCCCCCEEEEC		26.8830631047
293PhosphorylationLCRNLGSSEVVYKLP
EECCCCCCCEEEECC		32.3930631047
297PhosphorylationLGSSEVVYKLPTQSS
CCCCCEEEECCCCCC		16.3930631047
350PhosphorylationMRQADKISSSFSKGQ
HHHHHHCCCCCCCCC		26.1829449344
351PhosphorylationRQADKISSSFSKGQP
HHHHHCCCCCCCCCC		38.5929449344
352PhosphorylationQADKISSSFSKGQPL
HHHHCCCCCCCCCCC		27.0924719451
354PhosphorylationDKISSSFSKGQPLPP
HHCCCCCCCCCCCCC		37.5129449344
355MethylationKISSSFSKGQPLPPL
HCCCCCCCCCCCCCC		60.60115977647
388PhosphorylationPKWIRRPTGVSFAFG
CCCCCCCCCCEEEEC		48.69-
425PhosphorylationLVFISQVTTESEFLM
EEEEEECCCHHHHHH		19.7423879269
426PhosphorylationVFISQVTTESEFLMR
EEEEECCCHHHHHHH		38.3623879269
428PhosphorylationISQVTTESEFLMRSA
EEECCCHHHHHHHHH		31.4023879269
472PhosphorylationLWQFLKVTLEQDSRM
HHHHHHHHHCHHHHH		24.0024719451
509PhosphorylationSDVGLGESPQPKGND
HCCCCCCCCCCCCCC		27.34-
679PhosphorylationQEGSRALTSEARLCY
HHHHHCCCCCCEEHH		24.4428122231
680PhosphorylationEGSRALTSEARLCYV
HHHHCCCCCCEEHHH		30.0628122231
686PhosphorylationTSEARLCYVCSGSVE
CCCCEEHHHHCCHHH		14.7528122231
689PhosphorylationARLCYVCSGSVERLV
CEEHHHHCCHHHHHH		24.8628122231
691PhosphorylationLCYVCSGSVERLVEC
EHHHHCCHHHHHHHH		12.4328122231
707PhosphorylationAKCHQALSPMALQDL
HHHHHHCCHHHHHHH		18.6929978859
762PhosphorylationGSLATAMSFLPRDCA
CCHHHHHHCCCCCCC		22.5930257219
809PhosphorylationVVGATLHSKETSSYR
EEECEECCCCCCCCC		34.99-
819PhosphorylationTSSYRLGSQPSHQVP
CCCCCCCCCCCCCCC		43.4320873877
822PhosphorylationYRLGSQPSHQVPTPS
CCCCCCCCCCCCCCC		20.9320873877
827PhosphorylationQPSHQVPTPSPRPRV
CCCCCCCCCCCCCCC		37.2320873877
829PhosphorylationSHQVPTPSPRPRVFT
CCCCCCCCCCCCCCC		35.7020873877
836PhosphorylationSPRPRVFTPQSSPAM
CCCCCCCCCCCCCCC		19.98-
933PhosphorylationGSTSLPETPRLFPLL
CCCCCCCCCCEECCC		16.2724719451
1098PhosphorylationLSATDLKTKRKLEEA
CCHHHHHHHHHHHHH		43.3022210691
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseKLHL12Q53G59
PMID:22358839
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SC31B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SC31B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TCPH_HUMANCCT7physical
26186194
TCPG_HUMANCCT3physical
26186194
TCPW_HUMANCCT6Bphysical
26186194
TCPZ_HUMANCCT6Aphysical
26186194
TCPB_HUMANCCT2physical
26186194
TCPD_HUMANCCT4physical
26186194
TCPA_HUMANTCP1physical
26186194
TCPH_HUMANCCT7physical
28514442
TCPW_HUMANCCT6Bphysical
28514442
TCPB_HUMANCCT2physical
28514442
TCPZ_HUMANCCT6Aphysical
28514442
TCPA_HUMANTCP1physical
28514442
TCPG_HUMANCCT3physical
28514442
TCPE_HUMANCCT5physical
28514442
TCPD_HUMANCCT4physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SC31B_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory