FOXS1_HUMAN - dbPTM
FOXS1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FOXS1_HUMAN
UniProt AC O43638
Protein Name Forkhead box protein S1
Gene Name FOXS1
Organism Homo sapiens (Human).
Sequence Length 330
Subcellular Localization Nucleus .
Protein Description Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity)..
Protein Sequence MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
55PhosphorylationIMGRFAFYRHNRPGW
HHHHHHHHCCCCCCH		13.92-
65PhosphorylationNRPGWQNSIRHNLSL
CCCCHHHHHHHCCCC		13.1027251275
116MethylationRRRRRFTRQTGAEGT
HHHHHHHHHHCCCCC		29.38-
124MethylationQTGAEGTRGPAKARR
HHCCCCCCCCCHHCC		61.01-
137PhosphorylationRRGPLRATSQDPGVP
CCCCCCCCCCCCCCC		22.0828857561
138PhosphorylationRGPLRATSQDPGVPN
CCCCCCCCCCCCCCC		31.4428857561
182PhosphorylationASMCPATTDGRPRPP
HHHCCCCCCCCCCCC		38.2624719451
210PhosphorylationPGELPVATSSSSCPA
CCCCCEECCCCCCCC		29.4027251275
211PhosphorylationGELPVATSSSSCPAF
CCCCEECCCCCCCCC		20.6327251275
212PhosphorylationELPVATSSSSCPAFG
CCCEECCCCCCCCCC		23.1627251275
213PhosphorylationLPVATSSSSCPAFGF
CCEECCCCCCCCCCC		35.4127251275
214PhosphorylationPVATSSSSCPAFGFP
CEECCCCCCCCCCCC		26.5227251275
229PhosphorylationAGFSEAESFNKAPTP
CCCCCHHHHCCCCCC		40.9626074081
235PhosphorylationESFNKAPTPVLSPES
HHHCCCCCCCCCCCC		30.7826074081
239PhosphorylationKAPTPVLSPESGIGS
CCCCCCCCCCCCCCC		27.1926074081
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FOXS1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FOXS1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FOXS1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RBPMS_HUMANRBPMSphysical
16189514
A4_HUMANAPPphysical
21832049
2AAB_HUMANPPP2R1Bphysical
26186194
2ABD_HUMANPPP2R2Dphysical
26186194
ACOX1_HUMANACOX1physical
26186194
KBTB6_HUMANKBTBD6physical
26186194
MIPEP_HUMANMIPEPphysical
26186194
PP2AA_HUMANPPP2CAphysical
26186194
HXD13_HUMANHOXD13physical
25609649
FOXC1_HUMANFOXC1physical
25609649
AKAP8_HUMANAKAP8physical
25609649
RALY_HUMANRALYphysical
25609649
SATB2_HUMANSATB2physical
25609649
UCRI_HUMANUQCRFS1physical
25609649
DSRAD_HUMANADARphysical
25609649
TF3C5_HUMANGTF3C5physical
25609649
HXB13_HUMANHOXB13physical
25609649
COPG1_HUMANCOPG1physical
25609649
CTBP2_HUMANCTBP2physical
25609649
DX39A_HUMANDDX39Aphysical
25609649
G45IP_HUMANGADD45GIP1physical
25609649
HXC13_HUMANHOXC13physical
25609649
LRWD1_HUMANLRWD1physical
25609649
RM38_HUMANMRPL38physical
25609649
SMCA5_HUMANSMARCA5physical
25609649
HDAC2_HUMANHDAC2physical
25609649
HXB9_HUMANHOXB9physical
25609649
COT1_HUMANNR2F1physical
25609649
ORC2_HUMANORC2physical
25609649
PRP39_HUMANPRPF39physical
25609649
SATB1_HUMANSATB1physical
25609649
ABCB7_HUMANABCB7physical
25609649
ADNP_HUMANADNPphysical
25609649
APC7_HUMANANAPC7physical
25609649
ARL8B_HUMANARL8Bphysical
25609649
BARX1_HUMANBARX1physical
25609649
DCAKD_HUMANDCAKDphysical
25609649
ERAL1_HUMANERAL1physical
25609649
FUBP3_HUMANFUBP3physical
25609649
P66B_HUMANGATAD2Bphysical
25609649
GLPK_HUMANGKphysical
25609649
TF3C2_HUMANGTF3C2physical
25609649
TF3C3_HUMANGTF3C3physical
25609649
TF3C4_HUMANGTF3C4physical
25609649
UFL1_HUMANUFL1physical
25609649
MP2K3_HUMANMAP2K3physical
25609649
MMS19_HUMANMMS19physical
25609649
RM03_HUMANMRPL3physical
25609649
PBX2_HUMANPBX2physical
25609649
PO2F1_HUMANPOU2F1physical
25609649
PO2F2_HUMANPOU2F2physical
25609649
RRAS2_HUMANRRAS2physical
25609649
TAF9_HUMANTAF9physical
25609649
WDHD1_HUMANWDHD1physical
25609649
WDR18_HUMANWDR18physical
25609649
TRM2A_HUMANTRMT2Aphysical
25609649
P4HA1_HUMANP4HA1physical
25609649
DNJC9_HUMANDNAJC9physical
25609649
NOP14_HUMANNOP14physical
25609649
RTCA_HUMANRTCAphysical
25609649
SMC2_HUMANSMC2physical
25609649
HNRL2_HUMANHNRNPUL2physical
25609649
SYIM_HUMANIARS2physical
25609649
LENG9_HUMANLENG9physical
25609649
MAGT1_HUMANMAGT1physical
25609649
P53_HUMANTP53physical
25609649
WDR55_HUMANWDR55physical
25609649
ZFR_HUMANZFRphysical
25609649
ZN598_HUMANZNF598physical
25609649
CMS1_HUMANCMSS1physical
25609649
FXR1_HUMANFXR1physical
25609649
MET13_HUMANMETTL13physical
25609649
PAPD1_HUMANMTPAPphysical
25609649
RBMX_HUMANRBMXphysical
25609649
TOR3A_HUMANTOR3Aphysical
25609649
2ABD_HUMANPPP2R2Dphysical
28514442
MIPEP_HUMANMIPEPphysical
28514442
2AAB_HUMANPPP2R1Bphysical
28514442
PP2AA_HUMANPPP2CAphysical
28514442
ACOX1_HUMANACOX1physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FOXS1_HUMAN

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Related Literatures of Post-Translational Modification

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