DCAKD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DCAKD_HUMAN
• UniProt AC: Q8WVC6
• Protein Name: Dephospho-CoA kinase domain-containing protein
• Gene Name: DCAKD
• Organism: Homo sapiens (Human).
• Sequence Length: 231
• Protein Sequence: MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEVLLENGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRNSLNRKDAEARINAQLPLTDKARMARHVLDNSGEWSVTKRQVILLHTELERSLEYLPLRFGVLTGLAAIASLLYLLTHYLLPYA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Ubiquitination	GKSSVIQVFQQLGCA CCHHHHHHHHHHCCE	3.00	22817900
21	Ubiquitination	KSSVIQVFQQLGCAV CHHHHHHHHHHCCEE	1.88	22817900
24	Ubiquitination	VIQVFQQLGCAVIDV HHHHHHHHCCEEEEH	4.18	22817900
67	Ubiquitination	ENGDINRKVLGDLIF ECCCCCHHHHHHHHH	37.01	22053931
67	Ubiquitination	ENGDINRKVLGDLIF ECCCCCHHHHHHHHH	37.01	23000965
67 (in isoform 2)	Ubiquitination	-	37.01	21890473
67 (in isoform 1)	Ubiquitination	-	37.01	21890473
85	Ubiquitination	DRRQLLNAITHPEIR CHHHHHHHHHCHHHH	14.18	21890473
97	Ubiquitination	EIRKEMMKETFKYFL HHHHHHHHHHHHHHH	52.90	22817900
101	Ubiquitination	EMMKETFKYFLRGYR HHHHHHHHHHHHHCC	42.38	21890473
101 (in isoform 1)	Ubiquitination	-	42.38	21890473
109	Phosphorylation	YFLRGYRYVILDIPL HHHHHCCEEEEECHH	5.37	-
121	Ubiquitination	IPLLFETKKLLKYMK CHHHHCHHHHHHHCC	33.94	22817900
121 (in isoform 1)	Ubiquitination	-	33.94	21890473
121	Acetylation	IPLLFETKKLLKYMK CHHHHCHHHHHHHCC	33.94	19829069
122	Ubiquitination	PLLFETKKLLKYMKH HHHHCHHHHHHHCCC	67.48	22817900
125	Ubiquitination	FETKKLLKYMKHTVV HCHHHHHHHCCCEEE	54.45	22817900
126	Phosphorylation	ETKKLLKYMKHTVVV CHHHHHHHCCCEEEE	16.03	-
134	Phosphorylation	MKHTVVVYCDRDTQL CCCEEEEEECCHHHH	4.14	21253578
149	Phosphorylation	ARLMRRNSLNRKDAE HHHHHHHCCCHHHHH	25.80	22167270
168 (in isoform 1)	Ubiquitination	-	32.43	21890473
168	Ubiquitination	AQLPLTDKARMARHV CCCCCCCHHHHHHHH	32.43	22817900
186	Acetylation	SGEWSVTKRQVILLH CCCCCCCHHEEEEEE	38.38	25953088
186 (in isoform 1)	Ubiquitination	-	38.38	21890473
186	Ubiquitination	SGEWSVTKRQVILLH CCCCCCCHHEEEEEE	38.38	32142685

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DCAKD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DCAKD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DCAKD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCHL_HUMAN	HCCS	physical	27173435
COMT_HUMAN	COMT	physical	27173435
RDH11_HUMAN	RDH11	physical	27173435
ESYT1_HUMAN	ESYT1	physical	27173435
TMX1_HUMAN	TMX1	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.