| UniProt ID | HXB9_HUMAN | |
|---|---|---|
| UniProt AC | P17482 | |
| Protein Name | Homeobox protein Hox-B9 | |
| Gene Name | HOXB9 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 250 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. | |
| Protein Sequence | MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 27 | Acetylation | SEDAPPAKFPSGQYA CCCCCCCCCCCCCCC | 64.68 | 117897627 | |
| 30 | Phosphorylation | APPAKFPSGQYASSR CCCCCCCCCCCCCCC | 41.48 | - | |
| 33 | Phosphorylation | AKFPSGQYASSRQPG CCCCCCCCCCCCCCC | 16.39 | - | |
| 35 | Phosphorylation | FPSGQYASSRQPGHA CCCCCCCCCCCCCCC | 22.56 | - | |
| 36 | Phosphorylation | PSGQYASSRQPGHAE CCCCCCCCCCCCCCH | 27.11 | - | |
| 67 | Phosphorylation | GASWAPLSPHASGSL CCEECCCCCCCCCCC | 17.36 | 29978859 | |
| 71 | Phosphorylation | APLSPHASGSLPSVY CCCCCCCCCCCCCCC | 26.36 | 29978859 | |
| 73 | Phosphorylation | LSPHASGSLPSVYHP CCCCCCCCCCCCCCC | 34.31 | 29978859 | |
| 76 | Phosphorylation | HASGSLPSVYHPYIQ CCCCCCCCCCCCCCC | 40.37 | 29978859 | |
| 78 | Phosphorylation | SGSLPSVYHPYIQPQ CCCCCCCCCCCCCCC | 11.04 | 29978859 | |
| 81 | Phosphorylation | LPSVYHPYIQPQGVP CCCCCCCCCCCCCCC | 10.01 | 29978859 | |
| 93 | Methylation | GVPPAESRYLRTWLE CCCCHHHHHHHHCCC | 26.47 | 115479591 | |
| 96 | Methylation | PAESRYLRTWLEPAP CHHHHHHHHCCCCCC | 18.21 | 115479603 | |
| 117 | Acetylation | GQGQAAVKAEPLLGA CCCCCCEECCCCCCC | 42.16 | 30589329 | |
| 117 | Sumoylation | GQGQAAVKAEPLLGA CCCCCCEECCCCCCC | 42.16 | 28112733 | |
| 130 | Ubiquitination | GAPGELLKQGTPEYS CCCHHHHHCCCCCCE | 60.34 | - | |
| 133 | Phosphorylation | GELLKQGTPEYSLET HHHHHCCCCCCEEEC | 15.51 | 28112733 | |
| 136 | Phosphorylation | LKQGTPEYSLETSAG HHCCCCCCEEECHHH | 21.54 | 23186163 | |
| 137 | Phosphorylation | KQGTPEYSLETSAGR HCCCCCCEEECHHHH | 20.33 | 23186163 | |
| 183 | Methylation | SANWLHARSSRKKRC CHHHHHHHCCCCCCC | 25.15 | 115479597 | |
| 192 | Phosphorylation | SRKKRCPYTKYQTLE CCCCCCCCCCCCCHH | 21.35 | 28634298 | |
| 193 | Phosphorylation | RKKRCPYTKYQTLEL CCCCCCCCCCCCHHH | 14.39 | 28634298 | |
| 195 | Phosphorylation | KRCPYTKYQTLELEK CCCCCCCCCCHHHHH | 10.03 | 28634298 | |
| 197 | Phosphorylation | CPYTKYQTLELEKEF CCCCCCCCHHHHHHH | 21.07 | 28634298 | |
| 239 | Acetylation | WFQNRRMKMKKMNKE HHHHHHHHHHHHHHH | 45.84 | 7257703 | |
| 241 | Acetylation | QNRRMKMKKMNKEQG HHHHHHHHHHHHHHC | 43.27 | 7257713 | |
| 242 | Acetylation | NRRMKMKKMNKEQGK HHHHHHHHHHHHHCC | 44.18 | 7257723 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HXB9_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HXB9_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HXB9_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KR412_HUMAN | KRTAP4-12 | physical | 16189514 | |
| MDFI_HUMAN | MDFI | physical | 16189514 | |
| RBPMS_HUMAN | RBPMS | physical | 16189514 | |
| SAT1_HUMAN | SAT1 | physical | 16189514 | |
| BTG1_HUMAN | BTG1 | physical | 10617598 | |
| BTG2_HUMAN | BTG2 | physical | 10617598 | |
| SOX15_HUMAN | SOX15 | physical | 20211142 | |
| MBB1A_HUMAN | MYBBP1A | physical | 20211142 | |
| PHTF1_HUMAN | PHTF1 | physical | 20211142 | |
| ING4_HUMAN | ING4 | physical | 20211142 | |
| ZN408_HUMAN | ZNF408 | physical | 20211142 | |
| HOP_HUMAN | HOPX | physical | 20211142 | |
| SPZ1_HUMAN | SPZ1 | physical | 20211142 | |
| MDFI_HUMAN | MDFI | physical | 19060904 | |
| SAT1_HUMAN | SAT1 | physical | 19060904 | |
| TAL1_HUMAN | TAL1 | physical | 21988832 | |
| KRA59_HUMAN | KRTAP5-9 | physical | 25416956 | |
| SAT1_HUMAN | SAT1 | physical | 25416956 | |
| TRIP6_HUMAN | TRIP6 | physical | 25416956 | |
| PNMA1_HUMAN | PNMA1 | physical | 25416956 | |
| CACO2_HUMAN | CALCOCO2 | physical | 25416956 | |
| TRIM1_HUMAN | MID2 | physical | 25416956 | |
| KR109_HUMAN | KRTAP10-9 | physical | 25416956 | |
| LZTS2_HUMAN | LZTS2 | physical | 21516116 | |
| KAT2B_HUMAN | KAT2B | physical | 27613418 | |
| SIR1_HUMAN | SIRT1 | physical | 27613418 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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