| UniProt ID | ZN408_HUMAN | |
|---|---|---|
| UniProt AC | Q9H9D4 | |
| Protein Name | Zinc finger protein 408 | |
| Gene Name | ZNF408 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 720 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | May be involved in transcriptional regulation.. | |
| Protein Sequence | MEEAEELLLEGKKALQLAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 225 | Phosphorylation | DPGSQSPSGIQAENM CCCCCCCCCCCCCCC | 54.50 | 24275569 | |
| 234 | Phosphorylation | IQAENMVSPGLKFPT CCCCCCCCCCCCCCC | 11.50 | 24719451 | |
| 311 | Phosphorylation | YLAKKLHSPSDQCPP CHHHHCCCCCCCCCC | 36.21 | 25159151 | |
| 313 | Phosphorylation | AKKLHSPSDQCPPRA HHHCCCCCCCCCCCC | 43.24 | 27732954 | |
| 322 | Phosphorylation | QCPPRAKTPEPGAQQ CCCCCCCCCCCCCHH | 31.72 | 30266825 | |
| 330 | Phosphorylation | PEPGAQQSGFPTLSR CCCCCHHCCCCCCCC | 30.26 | 23403867 | |
| 334 | Phosphorylation | AQQSGFPTLSRSPPG CHHCCCCCCCCCCCC | 34.79 | 23403867 | |
| 336 | Phosphorylation | QSGFPTLSRSPPGPA HCCCCCCCCCCCCCC | 32.94 | 23403867 | |
| 338 | Phosphorylation | GFPTLSRSPPGPAGS CCCCCCCCCCCCCCC | 31.88 | 30266825 | |
| 345 | Phosphorylation | SPPGPAGSSPKQGRR CCCCCCCCCCCCCCC | 45.64 | 25056879 | |
| 346 | Phosphorylation | PPGPAGSSPKQGRRY CCCCCCCCCCCCCCE | 34.89 | 28985074 | |
| 432 | Phosphorylation | KEHQVVHSGARPFAC HHCCEECCCCCCCCC | 23.65 | 25159151 | |
| 451 | Phosphorylation | KAFARRPSLRLHRKT HHHHHCCCCCCCCCC | 25.06 | 28258704 | |
| 491 | Phosphorylation | RNHMRLHTGEKPFLC CCCEECCCCCCCCCC | 52.18 | 21857030 | |
| 494 | Sumoylation | MRLHTGEKPFLCPHC EECCCCCCCCCCCCC | 42.27 | - | |
| 494 | Sumoylation | MRLHTGEKPFLCPHC EECCCCCCCCCCCCC | 42.27 | - | |
| 512 | Methylation | FRQRGNLRGHLRLHT HHHHCCCCCCEEEEC | 34.19 | 54561957 | |
| 512 | Dimethylation | FRQRGNLRGHLRLHT HHHHCCCCCCEEEEC | 34.19 | - | |
| 519 | Phosphorylation | RGHLRLHTGERPYRC CCCEEEECCCCCCCC | 45.38 | - | |
| 547 | Phosphorylation | RRHLISHTGEAHLCP HHHHHHHCCCCCCCC | 29.90 | 28555341 | |
| 574 | Phosphorylation | RAHERLHSGERPFPC HHHHHHCCCCCCCCC | 47.11 | 29214152 | |
| 593 | Sumoylation | RAYTLATKLRRHLKS HHHHHHHHHHHHHHH | 34.10 | - | |
| 593 | Sumoylation | RAYTLATKLRRHLKS HHHHHHHHHHHHHHH | 34.10 | - | |
| 605 | Sumoylation | LKSHLEDKPYRCPTC HHHHHCCCCCCCCCC | 34.28 | - | |
| 605 | Sumoylation | LKSHLEDKPYRCPTC HHHHHCCCCCCCCCC | 34.28 | - | |
| 628 | Phosphorylation | SLRRHQLSHRPEAPC HHHHHCCCCCCCCCC | 15.75 | 28348404 | |
| 636 | Phosphorylation | HRPEAPCSPPSVPSA CCCCCCCCCCCCCCC | 38.49 | 28348404 | |
| 639 | Phosphorylation | EAPCSPPSVPSAASE CCCCCCCCCCCCCCC | 50.47 | 28348404 | |
| 668 | Phosphorylation | THREEEVSPARDVVE CCCCCCCCCCCCEEE | 19.00 | 21815630 | |
| 681 | Phosphorylation | VEVTISESQEKCFVV EEEEECCCCCCEEEC | 36.53 | 25003641 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZN408_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZN408_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZN408_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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