| UniProt ID | CREL1_HUMAN | |
|---|---|---|
| UniProt AC | Q96HD1 | |
| Protein Name | Cysteine-rich with EGF-like domain protein 1 | |
| Gene Name | CRELD1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 420 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 58 | Ubiquitination | GLVDSFNKGLERTIR HHHHHHHHHHHHHHH | 63.96 | - | |
| 79 | N-linked_Glycosylation | NTAWEEENLSKYKDS CCCHHHHHHHHCCCC | 53.55 | UniProtKB CARBOHYD | |
| 82 | Ubiquitination | WEEENLSKYKDSETR HHHHHHHHCCCCHHH | 60.53 | - | |
| 159 | O-linked_Glycosylation | CLPCPGGTERPCGGY CEECCCCCCCCCCCC | 34.43 | OGP | |
| 205 | N-linked_Glycosylation | GYFEAERNASHLVCS CHHHCCCCCCCCHHH | 36.98 | UniProtKB CARBOHYD | |
| 288 | Methylation | CMGAGPGRCKKCSPG CCCCCCCCCCCCCCC | 32.01 | - | |
| 324 | Phosphorylation | ENKQCENTEGGYRCI CCCCCCCCCCCEEEE | 17.45 | - | |
| 328 | Phosphorylation | CENTEGGYRCICAEG CCCCCCCEEEEECCC | 17.11 | - | |
| 356 | Phosphorylation | PESAGFFSEMTEDEL CCCCCCCCCCCHHHH | 24.97 | 24719451 | |
| 356 (in isoform 2) | Phosphorylation | - | 24.97 | 24719451 | |
| 363 | Phosphorylation | SEMTEDELVVLQQMF CCCCHHHHHHHHHHH | 5.09 | 24719451 | |
| 363 (in isoform 2) | Phosphorylation | - | 5.09 | 24719451 | |
| 370 (in isoform 2) | Phosphorylation | - | 4.39 | 25072903 | |
| 374 (in isoform 2) | Phosphorylation | - | 1.85 | 25072903 | |
| 375 (in isoform 2) | Phosphorylation | - | 0.77 | 25072903 | |
| 376 (in isoform 2) | Phosphorylation | - | 1.46 | 25072903 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CREL1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CREL1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CREL1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KAT5_HUMAN | KAT5 | physical | 16169070 | |
| DPOA2_HUMAN | POLA2 | physical | 16169070 | |
| CSN6_HUMAN | COPS6 | physical | 16169070 | |
| EF1G_HUMAN | EEF1G | physical | 16169070 | |
| GDF9_HUMAN | GDF9 | physical | 16169070 | |
| PTN_HUMAN | PTN | physical | 16169070 | |
| SETB1_HUMAN | SETDB1 | physical | 16169070 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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