| UniProt ID | TRIM1_HUMAN | |
|---|---|---|
| UniProt AC | Q9UJV3 | |
| Protein Name | Probable E3 ubiquitin-protein ligase MID2 | |
| Gene Name | MID2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 735 | |
| Subcellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Microtubule-associated. | |
| Protein Description | May play a role in microtubule stabilization.. | |
| Protein Sequence | MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNCRPQESPYVSGMKTCH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Phosphorylation | NASGGLFSLKMETLE ECCCCEEEEEEEECC | 31.93 | 24719451 | |
| 94 | Ubiquitination | HRGLDGLKRNVTLQN CCCCHHHHCCEEHHH | 47.67 | - | |
| 98 | Phosphorylation | DGLKRNVTLQNIIDR HHHHCCEEHHHHHHH | 26.61 | 28450419 | |
| 110 | Phosphorylation | IDRFQKASVSGPNSP HHHHHHHCCCCCCCC | 24.69 | 23403867 | |
| 112 | Phosphorylation | RFQKASVSGPNSPSE HHHHHCCCCCCCCCH | 46.14 | 26055452 | |
| 116 | Phosphorylation | ASVSGPNSPSESRRE HCCCCCCCCCHHHHH | 32.70 | 21712546 | |
| 118 | Phosphorylation | VSGPNSPSESRRERT CCCCCCCCHHHHHCC | 48.28 | 23403867 | |
| 120 | Phosphorylation | GPNSPSESRRERTYR CCCCCCHHHHHCCCC | 40.76 | 23403867 | |
| 169 | Phosphorylation | CDRCLRATHPNKKPF HHHHHHCCCCCCCCC | 31.28 | 29083192 | |
| 177 | Phosphorylation | HPNKKPFTSHRLVEP CCCCCCCCCCCCCCC | 31.95 | 29083192 | |
| 178 | Phosphorylation | PNKKPFTSHRLVEPV CCCCCCCCCCCCCCC | 13.64 | 29083192 | |
| 242 | Phosphorylation | RFEKLKQTLEMNLTN HHHHHHHHHHHHHHH | 24.09 | 24505115 | |
| 311 | Acetylation | IKETKVMKLRKLAQQ ECHHHHHHHHHHHHH | 48.40 | 19816947 | |
| 398 | Phosphorylation | KLLEGLDYLTAPNPP HHHCCCCCCCCCCCC | 15.82 | 21394647 | |
| 400 | Phosphorylation | LEGLDYLTAPNPPSI HCCCCCCCCCCCCCH | 33.56 | 29507054 | |
| 469 | Phosphorylation | RKCKEAVSCSRLAGA HHHHHHHCHHHHCCC | 17.27 | 23403867 | |
| 471 | Phosphorylation | CKEAVSCSRLAGAPR HHHHHCHHHHCCCCC | 23.87 | 23403867 | |
| 498 | Phosphorylation | PNIKQNHYTVHGLQS CCCCCCCEEEEEECC | 20.29 | 24043423 | |
| 499 | Phosphorylation | NIKQNHYTVHGLQSG CCCCCCEEEEEECCC | 9.85 | 24043423 | |
| 505 | Phosphorylation | YTVHGLQSGTRYIFI EEEEEECCCCEEEEE | 47.37 | 24043423 | |
| 507 | Phosphorylation | VHGLQSGTRYIFIVK EEEECCCCEEEEEEE | 26.08 | 24043423 | |
| 530 | Ubiquitination | NSEPTRLKTNSQPFK CCCCCCCCCCCCCCC | 42.23 | - | |
| 543 | Phosphorylation | FKLDPKMTHKKLKIS CCCCHHCCCCEEEEC | 36.35 | 23403867 | |
| 550 | Phosphorylation | THKKLKISNDGLQME CCCEEEECCCCCCCC | 27.55 | 22210691 | |
| 623 | Phosphorylation | EWIGKNASSWVFSRC CCCCCCCCHHHHHCC | 33.84 | - | |
| 725 | Phosphorylation | CNCRPQESPYVSGMK CCCCCCCCCCCCCCC | 19.11 | 26330541 | |
| 727 | Phosphorylation | CRPQESPYVSGMKTC CCCCCCCCCCCCCCC | 19.27 | 26267517 | |
| 729 | Phosphorylation | PQESPYVSGMKTCH- CCCCCCCCCCCCCC- | 27.59 | 26330541 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TRIM1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TRIM1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TRIM1_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 300928 | Mental retardation, X-linked 101 (MRX101) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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