ZN785_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN785_HUMAN
• UniProt AC: A8K8V0
• Protein Name: Zinc finger protein 785
• Gene Name: ZNF785
• Organism: Homo sapiens (Human).
• Sequence Length: 405
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGPPLAPRPAHVPGEAGPRRTRESRPGAVSFADVAVYFSPEEWECLRPAQRALYRDVMRETFGHLGALGFSVPKPAFISWVEGEVEAWSPEAQDPDGESSAAFSRGQGQEAGSRDGNEEKERLKKCPKQKEVAHEVAVKEWWPSVACPEFCNPRQSPMNPWLKDTLTRRLPHSCPDCGRNFSYPSLLASHQRVHSGERPFSCGQCQARFSQRRYLLQHQFIHTGEKPYPCPDCGRRFRQRGSLAIHRRAHTGEKPYACSDCKSRFTYPYLLAIHQRKHTGEKPYSCPDCSLRFAYTSLLAIHRRIHTGEKPYPCPDCGRRFTYSSLLLSHRRIHSDSRPFPCVECGKGFKRKTALEAHRWIHRSCSERRAWQQAVVGRSEPIPVLGGKDPPVHFRHFPDIFQECG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Phosphorylation	YRDVMRETFGHLGAL HHHHHHHHHCCHHCC	25.26	27794612
71	Phosphorylation	HLGALGFSVPKPAFI CHHCCCCCCCCCCEE	35.39	27794612
71 (in isoform 2)	Phosphorylation	-	35.39	22210691
79 (in isoform 2)	Phosphorylation	-	20.72	22210691
89 (in isoform 2)	Phosphorylation	-	21.65	22210691
167	Phosphorylation	PWLKDTLTRRLPHSC HHHHHHHHHCCCCCC	18.81	26657352
183	Phosphorylation	DCGRNFSYPSLLASH CCCCCCCHHHHHHHC	7.84	25884760
195	Phosphorylation	ASHQRVHSGERPFSC HHCCCCCCCCCCCCC	39.22	28555341
223	Phosphorylation	LQHQFIHTGEKPYPC HHHCEEECCCCCCCC	42.07	-
266	Phosphorylation	SDCKSRFTYPYLLAI CCCCHHCCHHHHHHH	23.60	24719451
269	Phosphorylation	KSRFTYPYLLAIHQR CHHCCHHHHHHHHCC	12.16	24719451
279	Phosphorylation	AIHQRKHTGEKPYSC HHHCCCCCCCCCCCC	50.50	23532336
307	Phosphorylation	AIHRRIHTGEKPYPC HHHHHHHCCCCCCCC	44.67	28111955
335	Phosphorylation	LSHRRIHSDSRPFPC HHCCCCCCCCCCCCC	34.60	29214152
353	Phosphorylation	GKGFKRKTALEAHRW CCCCCHHHHHHHHHH	40.27	25690035

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN785_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN785_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN785_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR101_HUMAN	KRTAP10-1	physical	25416956
BEND3_HUMAN	BEND3	physical	28514442
DOCK6_HUMAN	DOCK6	physical	28514442
TRIO_HUMAN	TRIO	physical	28514442
SMRCD_HUMAN	SMARCAD1	physical	28514442
LZTS2_HUMAN	LZTS2	physical	28514442
MTCL1_HUMAN	MTCL1	physical	28514442
KIF7_HUMAN	KIF7	physical	28514442
PZRN3_HUMAN	PDZRN3	physical	28514442
P2R3A_HUMAN	PPP2R3A	physical	28514442
SOGA1_HUMAN	SOGA1	physical	28514442
SUFU_HUMAN	SUFU	physical	28514442
2A5E_HUMAN	PPP2R5E	physical	28514442
UBP34_HUMAN	USP34	physical	28514442
ZBTB1_HUMAN	ZBTB1	physical	28514442
RBAK_HUMAN	RBAK	physical	28514442
ANR52_HUMAN	ANKRD52	physical	28514442
DHX32_HUMAN	DHX32	physical	28514442
ZN747_HUMAN	ZNF747	physical	28514442
TF3C2_HUMAN	GTF3C2	physical	28514442
MILK1_HUMAN	MICALL1	physical	28514442
ODBB_HUMAN	BCKDHB	physical	28514442
P4R3A_HUMAN	SMEK1	physical	28514442
MYOME_HUMAN	PDE4DIP	physical	28514442
TRI41_HUMAN	TRIM41	physical	28514442
SHCBP_HUMAN	SHCBP1	physical	28514442
ANR28_HUMAN	ANKRD28	physical	28514442
FBX11_HUMAN	FBXO11	physical	28514442
TF3C1_HUMAN	GTF3C1	physical	28514442
ERBIN_HUMAN	ERBB2IP	physical	28514442
APC_HUMAN	APC	physical	28514442
SIR1_HUMAN	SIRT1	physical	28514442
TIF1B_HUMAN	TRIM28	physical	28514442
TF3C3_HUMAN	GTF3C3	physical	28514442
CYTSA_HUMAN	SPECC1L	physical	28514442
SELO_HUMAN	SELO	physical	28514442
GEMI_HUMAN	GMNN	physical	28514442
TIF1A_HUMAN	TRIM24	physical	28514442
AGGF1_HUMAN	AGGF1	physical	28514442
ACHA9_HUMAN	CHRNA9	physical	28514442
Z324A_HUMAN	ZNF324	physical	28514442
CSKP_HUMAN	CASK	physical	28514442
RNF31_HUMAN	RNF31	physical	28514442
PP2AA_HUMAN	PPP2CA	physical	28514442
PLCG1_HUMAN	PLCG1	physical	28514442
KIF3A_HUMAN	KIF3A	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
PKN2_HUMAN	PKN2	physical	28514442
PKN3_HUMAN	PKN3	physical	28514442
ZN579_HUMAN	ZNF579	physical	28514442
PP6R2_HUMAN	PPP6R2	physical	28514442
P4R3B_HUMAN	SMEK2	physical	28514442
DOCK7_HUMAN	DOCK7	physical	28514442
ZN460_HUMAN	ZNF460	physical	28514442
APBP2_HUMAN	APPBP2	physical	28514442
PP4R2_HUMAN	PPP4R2	physical	28514442
CP24A_HUMAN	CYP24A1	physical	28514442
PNMA2_HUMAN	PNMA2	physical	28514442
GCP6_HUMAN	TUBGCP6	physical	28514442
NU160_HUMAN	NUP160	physical	28514442
CBX5_HUMAN	CBX5	physical	28514442
2AAB_HUMAN	PPP2R1B	physical	28514442
TF3C4_HUMAN	GTF3C4	physical	28514442
NUP85_HUMAN	NUP85	physical	28514442
TRI27_HUMAN	TRIM27	physical	28514442
2ABD_HUMAN	PPP2R2D	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.