| UniProt ID | MTCL1_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y4B5 | |
| Protein Name | Microtubule cross-linking factor 1 | |
| Gene Name | MTCL1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1905 | |
| Subcellular Localization | Lateral cell membrane. Apical cell membrane. Cytoplasm, cytoskeleton, spindle pole . Midbody . Cytoplasm, cytoskeleton . Colocalized with microtubules at the base of cilia. Gradually accumulates on the apicobasal microtubule bundles during epithelial | |
| Protein Description | Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells.. | |
| Protein Sequence | METLNGPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKESDGEESRLPQPKREGPVGGESDSEEMFEKTSGFGSGKPSEASEPCPTELLKAREDSEYLVTLKHEAQRLERTVERLITDTDSFLHDAGLRGGAPLPGPGLQGEEEQGEGDQQEPQLLGTINAKMKAFKKELQAFLEQVNRIGDGLSPLPHLTESSSFLSTVTSVSRDSPIGNLGKELGPDLQSRLKEQLEWQLGPARGDERESLRLRAARELHRRADGDTGSHGLGGQTCFSLEMEEEHLYALRWKELEMHSLALQNTLHERTWSDEKNLMQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEEGEEFTEGEHPETLSRLGELGVQGGHQADGPDHDSDRGCGFPVGEHSPHSRVQIGDHSLRLQTADRGQPHKQVVENQQLFSAFKALLEDFRAELREDERARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAESKGALKKEREVHQKLLADSHSLVMDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQLQKENSPRRGGSFLCDQKDGNVRPFPHQGSLRMPRPVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDDEPEEPPAHRPEREFRNRLPEEEENHKGNLQRAVSVSSMSEFQRLMDISPFLPEKGLPSTSSKEDVTPPLSPDDLKYIEEFNKSWDYTPNRGHNGGGPDLWADRTEVGRAGHEDSTEPFPDSSWYLTTSVTMTTDTMTSPEHCQKQPLRSHVLTEQSGLRVLHSPPAVRRVDSITAAGGEGPFPTSRARGSPGDTKGGPPEPMLSRWPCTSPRHSRDYVEGARRPLDSPLCTSLGFASPLHSLEMSKNLSDDMKEVAFSVRNAICSGPGELQVKDMACQTNGSRTMGTQTVQTISVGLQTEALRGSGVTSSPHKCLTPKAGGGATPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLPKADQPNNRTSPGMAQKGYSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPVVQDPFQKGLRAGSRSRSAEPRPELGPGQETGTNSRGRSPSPIGVGSEMCREEGGEGTPVKQDLSAPPGYTLTENVARILNKKLLEHALKEERRQAAHGPPGLHSDSHSLGDTAEPGPMENQTVLLTAPWGL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 43 | Phosphorylation | RRLHRAPSPARPFLK HHHHCCCCCCCHHHH | 28731282 | ||
| 65 | Phosphorylation | APGPAVPSSGRAPAP CCCCCCCCCCCCCCC | 30576142 | ||
| 66 | Phosphorylation | PGPAVPSSGRAPAPA CCCCCCCCCCCCCCC | 30576142 | ||
| 72 | Phosphorylation | SSGRAPAPAAPRSPN CCCCCCCCCCCCCCC | 19007248 | ||
| 77 | Phosphorylation | PAPAAPRSPNLAGKA CCCCCCCCCCCCCCC | 25159151 | ||
| 87 | Phosphorylation | LAGKAPPSPGSLAAP CCCCCCCCCCCCCCC | 30266825 | ||
| 90 | Phosphorylation | KAPPSPGSLAAPGRL CCCCCCCCCCCCCCC | 30266825 | ||
| 98 | Phosphorylation | LAAPGRLSRRSGGVP CCCCCCCCCCCCCCC | - | ||
| 142 | O-linked_Glycosylation | VAPAEPLSRAGKPPG CCCCCCHHHCCCCCC | 30379171 | ||
| 154 | Phosphorylation | PPGAEPPSAAAKGRK CCCCCCCCHHHHCCC | 24732914 | ||
| 178 | Phosphorylation | ARTVGPPTPAARIPA CCCCCCCCHHHHCCC | 28555341 | ||
| 187 | O-linked_Glycosylation | AARIPAVTLAVTSVA HHHCCCEEEEEEECC | 30379171 | ||
| 189 | Phosphorylation | RIPAVTLAVTSVAGS HCCCEEEEEEECCCC | 19691289 | ||
| 191 | Phosphorylation | PAVTLAVTSVAGSPA CCEEEEEEECCCCCC | 30266825 | ||
| 192 | Phosphorylation | AVTLAVTSVAGSPAR CEEEEEEECCCCCCH | 27987026 | ||
| 196 | Phosphorylation | AVTSVAGSPARCSRI EEEECCCCCCHHCCC | 30266825 | ||
| 204 | Phosphorylation | PARCSRISHTDSSSD CCHHCCCCCCCCCCC | 23663014 | ||
| 206 | Phosphorylation | RCSRISHTDSSSDLS HHCCCCCCCCCCCCC | 23663014 | ||
| 207 (in isoform 4) | Phosphorylation | - | 20068231 | ||
| 208 | Phosphorylation | SRISHTDSSSDLSDC CCCCCCCCCCCCCCC | 23663014 | ||
| 208 (in isoform 4) | Phosphorylation | - | 20068231 | ||
| 209 | Phosphorylation | RISHTDSSSDLSDCP CCCCCCCCCCCCCCC | 23663014 | ||
| 210 | Phosphorylation | ISHTDSSSDLSDCPS CCCCCCCCCCCCCCC | 23663014 | ||
| 210 (in isoform 4) | Ubiquitination | - | - | ||
| 213 | Phosphorylation | TDSSSDLSDCPSEPL CCCCCCCCCCCCCCC | 23663014 | ||
| 217 | Phosphorylation | SDLSDCPSEPLSDEQ CCCCCCCCCCCCHHH | 23663014 | ||
| 221 | Phosphorylation | DCPSEPLSDEQRLLP CCCCCCCCHHHHHHH | 23663014 | ||
| 231 | Phosphorylation | QRLLPAASSDAESGT HHHHHCCCCCCCCCC | 30266825 | ||
| 232 | Phosphorylation | RLLPAASSDAESGTG HHHHCCCCCCCCCCC | 30266825 | ||
| 236 | Phosphorylation | AASSDAESGTGSSDR CCCCCCCCCCCCCCC | 30206219 | ||
| 238 | Phosphorylation | SSDAESGTGSSDREP CCCCCCCCCCCCCCC | 30206219 | ||
| 240 | Phosphorylation | DAESGTGSSDREPPR CCCCCCCCCCCCCCC | 27174698 | ||
| 241 | Phosphorylation | AESGTGSSDREPPRG CCCCCCCCCCCCCCC | 27174698 | ||
| 251 | Phosphorylation | EPPRGAPTPSPAARG CCCCCCCCCCHHHCC | 29396449 | ||
| 253 | Phosphorylation | PRGAPTPSPAARGAP CCCCCCCCHHHCCCC | 21815630 | ||
| 258 | Phosphorylation | TPSPAARGAPPGSPE CCCHHHCCCCCCCCC | 20068231 | ||
| 261 | Phosphorylation | PAARGAPPGSPEPPA HHHCCCCCCCCCCCH | 20068231 | ||
| 262 | Phosphorylation | AARGAPPGSPEPPAL HHCCCCCCCCCCCHH | 18669648 | ||
| 263 | Phosphorylation | ARGAPPGSPEPPALL HCCCCCCCCCCCHHH | 29255136 | ||
| 284 | Phosphorylation | GACPGGRSIPSGVSG CCCCCCCCCCCCCCC | 26270265 | ||
| 287 | Phosphorylation | PGGRSIPSGVSGGFA CCCCCCCCCCCCCCC | 26270265 | ||
| 290 | Phosphorylation | RSIPSGVSGGFAGPG CCCCCCCCCCCCCCC | 26270265 | ||
| 306 | Phosphorylation | AEDVRGRSPPERPVP HHCCCCCCCCCCCCC | 30266825 | ||
| 315 | Phosphorylation | PERPVPGTPKEPSLG CCCCCCCCCCCCCCC | 25159151 | ||
| 320 | Phosphorylation | PGTPKEPSLGEQSRL CCCCCCCCCCCCCCC | 19691289 | ||
| 325 | Phosphorylation | EPSLGEQSRLVPAAE CCCCCCCCCCCCHHH | 19691289 | ||
| 345 | Phosphorylation | REMEELRSENDYLKD HHHHHHHHCCHHHHH | 25159151 | ||
| 351 | Ubiquitination | RSENDYLKDELDELR HHCCHHHHHHHHHHH | 33845483 | ||
| 354 | Ubiquitination | NDYLKDELDELRAEM CHHHHHHHHHHHHHH | 29967540 | ||
| 368 | Phosphorylation | MEEMRDSYLEEDVYQ HHHHHHHHHHHHHHH | 24275569 | ||
| 374 | Phosphorylation | SYLEEDVYQLQELRR HHHHHHHHHHHHHHH | 27642862 | ||
| 396 | Phosphorylation | NCRILQYRLRKAEQK HHHHHHHHHHHHHHH | 19691289 | ||
| 404 | Phosphorylation | LRKAEQKSLKVAETG HHHHHHHCCCHHHCC | 28348404 | ||
| 416 | Phosphorylation | ETGQVDGELIRSLEQ HCCCCCHHHHHHHHH | 19691289 | ||
| 432 | Phosphorylation | LKVAKDVSVRLHHEL HHHHHHHHHHHHHHH | 19007248 | ||
| 446 | Ubiquitination | LKTVEEKRAKAEDEN HHHHHHHHHHCHHHC | 33845483 | ||
| 480 | Phosphorylation | ELERLKESSLKRRST HHHHHHHHHHHHHHH | 26699800 | ||
| 481 | Phosphorylation | LERLKESSLKRRSTR HHHHHHHHHHHHHHH | 26699800 | ||
| 486 | Phosphorylation | ESSLKRRSTREMYKE HHHHHHHHHHHHHHH | 29449344 | ||
| 487 | Phosphorylation | SSLKRRSTREMYKEK HHHHHHHHHHHHHHH | 29449344 | ||
| 491 | Phosphorylation | RRSTREMYKEKKTFN HHHHHHHHHHHHCCC | 29449344 | ||
| 540 | Phosphorylation | LEQELQKYKSLYGDV HHHHHHHHHHHHCCC | 30576142 | ||
| 542 | Phosphorylation | QELQKYKSLYGDVDS HHHHHHHHHHCCCCC | 23403867 | ||
| 544 | Phosphorylation | LQKYKSLYGDVDSPL HHHHHHHHCCCCCCC | 23403867 | ||
| 549 | Phosphorylation | SLYGDVDSPLPTGEA HHHCCCCCCCCCCCC | 25159151 | ||
| 553 | Phosphorylation | DVDSPLPTGEAGGPP CCCCCCCCCCCCCCC | 28176443 | ||
| 561 | Phosphorylation | GEAGGPPSTREAELK CCCCCCCCHHHHHHH | 23403867 | ||
| 562 | Phosphorylation | EAGGPPSTREAELKL CCCCCCCHHHHHHHH | 23403867 | ||
| 563 | Phosphorylation | AGGPPSTREAELKLR CCCCCCHHHHHHHHH | 19691289 | ||
| 570 | Ubiquitination | REAELKLRLKLVEEE HHHHHHHHHHHHHHH | 29967540 | ||
| 581 | Ubiquitination | VEEEANILGRKIVEL HHHHHHHHCCEEEEE | 33845483 | ||
| 609 | Phosphorylation | MRGQQEREGPGRDHA HCCCCCCCCCCCCCC | 18669648 | ||
| 612 | Phosphorylation | QQEREGPGRDHAPSI CCCCCCCCCCCCCCC | 18669648 | ||
| 613 | Phosphorylation | QEREGPGRDHAPSIP CCCCCCCCCCCCCCC | 18669648 | ||
| 618 | Phosphorylation | PGRDHAPSIPTSPFG CCCCCCCCCCCCCCC | 30266825 | ||
| 621 | Phosphorylation | DHAPSIPTSPFGDSL CCCCCCCCCCCCCCC | 30266825 | ||
| 622 | Phosphorylation | HAPSIPTSPFGDSLE CCCCCCCCCCCCCCC | 30266825 | ||
| 627 | Phosphorylation | PTSPFGDSLESSTEL CCCCCCCCCCCCHHH | 30266825 | ||
| 630 | Phosphorylation | PFGDSLESSTELRRH CCCCCCCCCHHHHHH | 30266825 | ||
| 631 | Phosphorylation | FGDSLESSTELRRHL CCCCCCCCHHHHHHH | 23663014 | ||
| 632 | Phosphorylation | GDSLESSTELRRHLQ CCCCCCCHHHHHHHH | 23663014 | ||
| 651 | Phosphorylation | EAELLRRSISEIEDH HHHHHHHHHHHHHHH | 25159151 | ||
| 653 | Phosphorylation | ELLRRSISEIEDHNR HHHHHHHHHHHHHHH | 26699800 | ||
| 663 | O-linked_Glycosylation | EDHNRQLTHELSKFK HHHHHHHHHHHHCCC | 30379171 | ||
| 676 | Phosphorylation | FKFEPPREPGWLGEG CCCCCCCCCCCCCCC | 18669648 | ||
| 685 | Phosphorylation | GWLGEGASPGAGGGA CCCCCCCCCCCCCCC | 25159151 | ||
| 704 | Ubiquitination | ELKSARLQISELSGK HHHHCCHHHHHHHHC | 29967540 | ||
| 711 | Ubiquitination | QISELSGKVLKLQHE HHHHHHHCHHHHHHH | 33845483 | ||
| 736 | Ubiquitination | CDLAAHLGLRAPSPR HHHHHHHCCCCCCCC | 29967540 | ||
| 741 | Phosphorylation | HLGLRAPSPRDSDAE HHCCCCCCCCCCCCC | 23663014 | ||
| 745 | O-linked_Glycosylation | RAPSPRDSDAESDAG CCCCCCCCCCCCCCC | 30379171 | ||
| 745 | Phosphorylation | RAPSPRDSDAESDAG CCCCCCCCCCCCCCC | 23663014 | ||
| 749 | Phosphorylation | PRDSDAESDAGKKES CCCCCCCCCCCCCCC | 20166139 | ||
| 756 | Phosphorylation | SDAGKKESDGEESRL CCCCCCCCCCCCCCC | 25159151 | ||
| 761 | Phosphorylation | KESDGEESRLPQPKR CCCCCCCCCCCCCCC | 20873877 | ||
| 767 | Phosphorylation | ESRLPQPKREGPVGG CCCCCCCCCCCCCCC | 18669648 | ||
| 776 | Phosphorylation | EGPVGGESDSEEMFE CCCCCCCCCHHHHHH | 29255136 | ||
| 778 | Phosphorylation | PVGGESDSEEMFEKT CCCCCCCHHHHHHHC | 30266825 | ||
| 785 | Phosphorylation | SEEMFEKTSGFGSGK HHHHHHHCCCCCCCC | 25627689 | ||
| 786 | Phosphorylation | EEMFEKTSGFGSGKP HHHHHHCCCCCCCCC | 23312004 | ||
| 790 | Phosphorylation | EKTSGFGSGKPSEAS HHCCCCCCCCCCCCC | 25159151 | ||
| 794 | Phosphorylation | GFGSGKPSEASEPCP CCCCCCCCCCCCCCC | 23312004 | ||
| 806 | Ubiquitination | PCPTELLKAREDSEY CCCHHHHHHCCCCCC | 33845483 | ||
| 811 | Ubiquitination | LLKAREDSEYLVTLK HHHHCCCCCCEEHHH | 29967540 | ||
| 876 | Ubiquitination | PQLLGTINAKMKAFK CHHHHHHHHHHHHHH | 33845483 | ||
| 887 | Ubiquitination | KAFKKELQAFLEQVN HHHHHHHHHHHHHHH | 29967540 | ||
| 898 | Phosphorylation | EQVNRIGDGLSPLPH HHHHHHCCCCCCCCC | 18669648 | ||
| 901 | Phosphorylation | NRIGDGLSPLPHLTE HHHCCCCCCCCCCCC | 29255136 | ||
| 907 | Phosphorylation | LSPLPHLTESSSFLS CCCCCCCCCCCCHHH | 25850435 | ||
| 909 | Phosphorylation | PLPHLTESSSFLSTV CCCCCCCCCCHHHHH | 25850435 | ||
| 910 | Phosphorylation | LPHLTESSSFLSTVT CCCCCCCCCHHHHHH | 25850435 | ||
| 911 | Phosphorylation | PHLTESSSFLSTVTS CCCCCCCCHHHHHHH | 25850435 | ||
| 914 | Phosphorylation | TESSSFLSTVTSVSR CCCCCHHHHHHHCCC | 18669648 | ||
| 923 | Phosphorylation | VTSVSRDSPIGNLGK HHHCCCCCCCHHHHH | 25159151 | ||
| 926 | Ubiquitination | VSRDSPIGNLGKELG CCCCCCCHHHHHHHC | 29967540 | ||
| 933 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 935 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 937 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 938 | Phosphorylation | ELGPDLQSRLKEQLE HHCHHHHHHHHHHHH | - | ||
| 941 | Ubiquitination | PDLQSRLKEQLEWQL HHHHHHHHHHHHHHC | 33845483 | ||
| 941 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 946 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 947 (in isoform 4) | Phosphorylation | - | 23663014 | ||
| 956 | Ubiquitination | GPARGDERESLRLRA CCCCCCHHHHHHHHH | 29967540 | ||
| 966 (in isoform 4) | Phosphorylation | - | 20873877 | ||
| 971 | Ubiquitination | ARELHRRADGDTGSH HHHHHHHCCCCCCCC | 29967540 | ||
| 971 (in isoform 4) | Phosphorylation | - | 20873877 | ||
| 973 (in isoform 4) | Phosphorylation | - | 28796482 | ||
| 975 | Phosphorylation | HRRADGDTGSHGLGG HHHCCCCCCCCCCCC | 20860994 | ||
| 975 (in isoform 4) | Phosphorylation | - | 25159151 | ||
| 977 | Phosphorylation | RADGDTGSHGLGGQT HCCCCCCCCCCCCCC | 20860994 | ||
| 984 | Phosphorylation | SHGLGGQTCFSLEME CCCCCCCCEEEEEEC | 20860994 | ||
| 987 | Phosphorylation | LGGQTCFSLEMEEEH CCCCCEEEEEECHHH | - | ||
| 1007 | Phosphorylation | WKELEMHSLALQNTL HHHHHHHHHHHHHHH | 28555341 | ||
| 1010 | Ubiquitination | LEMHSLALQNTLHER HHHHHHHHHHHHHHC | 29967540 | ||
| 1013 | Phosphorylation | HSLALQNTLHERTWS HHHHHHHHHHHCCCH | 28555341 | ||
| 1018 | Phosphorylation | QNTLHERTWSDEKNL HHHHHHCCCHHHHHH | 21712546 | ||
| 1020 | Phosphorylation | TLHERTWSDEKNLMQ HHHHCCCHHHHHHHH | 21712546 | ||
| 1058 | Ubiquitination | WRQGKQMEEEGEEFT HHCCCCCHHCCCCCC | 29967540 | ||
| 1066 | Phosphorylation | EEGEEFTEGEHPETL HCCCCCCCCCCHHHH | 19691289 | ||
| 1069 | Phosphorylation | EEFTEGEHPETLSRL CCCCCCCCHHHHHHH | 18669648 | ||
| 1080 | Phosphorylation | LSRLGELGVQGGHQA HHHHHHCCCCCCCCC | 20068231 | ||
| 1086 | Ubiquitination | LGVQGGHQADGPDHD CCCCCCCCCCCCCCC | 29967540 | ||
| 1093 | Phosphorylation | QADGPDHDSDRGCGF CCCCCCCCCCCCCCC | 18669648 | ||
| 1094 | Phosphorylation | ADGPDHDSDRGCGFP CCCCCCCCCCCCCCC | 29449344 | ||
| 1098 | Phosphorylation | DHDSDRGCGFPVGEH CCCCCCCCCCCCCCC | 19651622 | ||
| 1102 | Phosphorylation | DRGCGFPVGEHSPHS CCCCCCCCCCCCCCC | 19651622 | ||
| 1106 | Phosphorylation | GFPVGEHSPHSRVQI CCCCCCCCCCCCCCC | 30266825 | ||
| 1108 | Phosphorylation | PVGEHSPHSRVQIGD CCCCCCCCCCCCCCC | 18669648 | ||
| 1109 | Phosphorylation | VGEHSPHSRVQIGDH CCCCCCCCCCCCCCC | 23663014 | ||
| 1114 | Ubiquitination | PHSRVQIGDHSLRLQ CCCCCCCCCCEEEEE | 33845483 | ||
| 1117 | Phosphorylation | RVQIGDHSLRLQTAD CCCCCCCEEEEEECC | 28857561 | ||
| 1119 | Phosphorylation | QIGDHSLRLQTADRG CCCCCEEEEEECCCC | 19691289 | ||
| 1122 | Phosphorylation | DHSLRLQTADRGQPH CCEEEEEECCCCCCC | 28555341 | ||
| 1169 | Phosphorylation | RLQQQYASDKAAWDV HHHHHHHHHHHHHHH | 24850871 | ||
| 1195 | Phosphorylation | LEEKTENKLGELGSS HHHHHHHCHHHHCCC | 19691289 | ||
| 1195 | Ubiquitination | LEEKTENKLGELGSS HHHHHHHCHHHHCCC | 33845483 | ||
| 1202 | Phosphorylation | KLGELGSSAESKGAL CHHHHCCCHHHHCCH | 21815630 | ||
| 1223 | Phosphorylation | HQKLLADSHSLVMDL HHHHHHCCCCHHHHH | 23403867 | ||
| 1225 | Phosphorylation | KLLADSHSLVMDLRW HHHHCCCCHHHHHHH | 23403867 | ||
| 1227 | Ubiquitination | LADSHSLVMDLRWQI HHCCCCHHHHHHHHH | 32015554 | ||
| 1236 | Ubiquitination | DLRWQIHHSEKNWNR HHHHHHHCCCCCCCH | 33845483 | ||
| 1241 | Phosphorylation | IHHSEKNWNREKVEL HHCCCCCCCHHHHHH | 18669648 | ||
| 1242 | Phosphorylation | HHSEKNWNREKVELL HCCCCCCCHHHHHHH | 18669648 | ||
| 1259 | Phosphorylation | LDRDRQEWERQKKEF HHHHHHHHHHHHHHH | 20068231 | ||
| 1263 | Phosphorylation | RQEWERQKKEFLWRI HHHHHHHHHHHHHHH | 18669648 | ||
| 1264 | Phosphorylation | QEWERQKKEFLWRIE HHHHHHHHHHHHHHH | 18669648 | ||
| 1269 | Phosphorylation | QKKEFLWRIEQLQKE HHHHHHHHHHHHHHH | 20068231 | ||
| 1273 | Phosphorylation | FLWRIEQLQKENSPR HHHHHHHHHHHCCCC | 18669648 | ||
| 1278 | Phosphorylation | EQLQKENSPRRGGSF HHHHHHCCCCCCCCC | 25159151 | ||
| 1278 | Ubiquitination | EQLQKENSPRRGGSF HHHHHHCCCCCCCCC | 29967540 | ||
| 1284 | Phosphorylation | NSPRRGGSFLCDQKD CCCCCCCCCCCCCCC | 20873877 | ||
| 1285 | Ubiquitination | SPRRGGSFLCDQKDG CCCCCCCCCCCCCCC | 29967540 | ||
| 1302 | Phosphorylation | RPFPHQGSLRMPRPV CCCCCCCCCCCCCCE | 20873877 | ||
| 1307 | Dimethylation | QGSLRMPRPVAMWPC CCCCCCCCCEEEEEC | - | ||
| 1307 | Methylation | QGSLRMPRPVAMWPC CCCCCCCCCEEEEEC | 30762495 | ||
| 1319 | Phosphorylation | WPCADADSIPFEDRP EECCCCCCCCCCCCC | 25159151 | ||
| 1328 | Phosphorylation | PFEDRPLSKLKESDR CCCCCCHHHCCHHHC | 23312004 | ||
| 1337 | Phosphorylation | LKESDRCSASENLYL CCHHHCCCCCCCEEE | 25627689 | ||
| 1342 | Phosphorylation | RCSASENLYLDALSL CCCCCCCEEEEECCC | 20068231 | ||
| 1348 | Phosphorylation | NLYLDALSLDDEPEE CEEEEECCCCCCCCC | 20068231 | ||
| 1356 | Phosphorylation | LDDEPEEPPAHRPER CCCCCCCCCCCCCHH | 16964243 | ||
| 1360 | Phosphorylation | PEEPPAHRPEREFRN CCCCCCCCCHHHHHH | 16964243 | ||
| 1362 | Phosphorylation | EPPAHRPEREFRNRL CCCCCCCHHHHHHCC | 16964243 | ||
| 1364 | Phosphorylation | PAHRPEREFRNRLPE CCCCCHHHHHHCCCH | 20068231 | ||
| 1376 | Phosphorylation | LPEEEENHKGNLQRA CCHHHHCCCCCHHHH | 18669648 | ||
| 1377 | Methylation | PEEEENHKGNLQRAV CHHHHCCCCCHHHHH | 72666633 | ||
| 1377 | Ubiquitination | PEEEENHKGNLQRAV CHHHHCCCCCHHHHH | - | ||
| 1379 | Phosphorylation | EEENHKGNLQRAVSV HHHCCCCCHHHHHHH | 18669648 | ||
| 1385 | Phosphorylation | GNLQRAVSVSSMSEF CCHHHHHHHHCHHHH | 29255136 | ||
| 1387 | Phosphorylation | LQRAVSVSSMSEFQR HHHHHHHHCHHHHHH | 29255136 | ||
| 1388 | Phosphorylation | QRAVSVSSMSEFQRL HHHHHHHCHHHHHHH | 25159151 | ||
| 1390 | Phosphorylation | AVSVSSMSEFQRLMD HHHHHCHHHHHHHHH | 22617229 | ||
| 1399 | Phosphorylation | FQRLMDISPFLPEKG HHHHHHCCCCCCCCC | 25159151 | ||
| 1403 | Phosphorylation | MDISPFLPEKGLPST HHCCCCCCCCCCCCC | 18669648 | ||
| 1408 | Phosphorylation | FLPEKGLPSTSSKED CCCCCCCCCCCCCCC | 18669648 | ||
| 1409 | Phosphorylation | LPEKGLPSTSSKEDV CCCCCCCCCCCCCCC | 23403867 | ||
| 1410 | Phosphorylation | PEKGLPSTSSKEDVT CCCCCCCCCCCCCCC | 23403867 | ||
| 1411 | Phosphorylation | EKGLPSTSSKEDVTP CCCCCCCCCCCCCCC | 23403867 | ||
| 1412 | Phosphorylation | KGLPSTSSKEDVTPP CCCCCCCCCCCCCCC | 28176443 | ||
| 1417 | Phosphorylation | TSSKEDVTPPLSPDD CCCCCCCCCCCCHHH | 29255136 | ||
| 1418 | Phosphorylation | SSKEDVTPPLSPDDL CCCCCCCCCCCHHHH | 18669648 | ||
| 1421 | Phosphorylation | EDVTPPLSPDDLKYI CCCCCCCCHHHHHHH | 29255136 | ||
| 1427 | Phosphorylation | LSPDDLKYIEEFNKS CCHHHHHHHHHHHHC | 18669648 | ||
| 1433 | Ubiquitination | KYIEEFNKSWDYTPN HHHHHHHHCCCCCCC | 33845483 | ||
| 1434 | Phosphorylation | YIEEFNKSWDYTPNR HHHHHHHCCCCCCCC | 22199227 | ||
| 1437 | Phosphorylation | EFNKSWDYTPNRGHN HHHHCCCCCCCCCCC | 19691289 | ||
| 1438 | Phosphorylation | FNKSWDYTPNRGHNG HHHCCCCCCCCCCCC | 19691289 | ||
| 1455 | Phosphorylation | PDLWADRTEVGRAGH CCCCCCCCCCCCCCC | 28555341 | ||
| 1470 | Phosphorylation | EDSTEPFPDSSWYLT CCCCCCCCCCCEEEE | 20068231 | ||
| 1474 | Ubiquitination | EPFPDSSWYLTTSVT CCCCCCCEEEEEEEE | 33845483 | ||
| 1488 | Phosphorylation | TMTTDTMTSPEHCQK EEECCCCCCHHHHHC | 26074081 | ||
| 1489 | Phosphorylation | MTTDTMTSPEHCQKQ EECCCCCCHHHHHCC | 26074081 | ||
| 1493 | Phosphorylation | TMTSPEHCQKQPLRS CCCCHHHHHCCCCCH | 18669648 | ||
| 1495 | Phosphorylation | TSPEHCQKQPLRSHV CCHHHHHCCCCCHHC | 18669648 | ||
| 1500 | Phosphorylation | CQKQPLRSHVLTEQS HHCCCCCHHCCCCCC | 28509920 | ||
| 1501 | Phosphorylation | QKQPLRSHVLTEQSG HCCCCCHHCCCCCCC | 18669648 | ||
| 1504 | Phosphorylation | PLRSHVLTEQSGLRV CCCHHCCCCCCCCEE | 28509920 | ||
| 1505 | Phosphorylation | LRSHVLTEQSGLRVL CCHHCCCCCCCCEEC | 18669648 | ||
| 1507 | Phosphorylation | SHVLTEQSGLRVLHS HHCCCCCCCCEECCC | 25159151 | ||
| 1512 | Phosphorylation | EQSGLRVLHSPPAVR CCCCCEECCCCCCEE | 18669648 | ||
| 1514 | Phosphorylation | SGLRVLHSPPAVRRV CCCEECCCCCCEEEC | 23927012 | ||
| 1523 | Phosphorylation | PAVRRVDSITAAGGE CCEEECCEEEECCCC | 25159151 | ||
| 1525 | Phosphorylation | VRRVDSITAAGGEGP EEECCEEEECCCCCC | 26462736 | ||
| 1535 | Phosphorylation | GGEGPFPTSRARGSP CCCCCCCCCCCCCCC | 21712546 | ||
| 1536 | Phosphorylation | GEGPFPTSRARGSPG CCCCCCCCCCCCCCC | 25159151 | ||
| 1541 | Phosphorylation | PTSRARGSPGDTKGG CCCCCCCCCCCCCCC | 23403867 | ||
| 1545 | Phosphorylation | ARGSPGDTKGGPPEP CCCCCCCCCCCCCCC | 29514088 | ||
| 1546 | Ubiquitination | RGSPGDTKGGPPEPM CCCCCCCCCCCCCCC | 32015554 | ||
| 1551 | Phosphorylation | DTKGGPPEPMLSRWP CCCCCCCCCCHHCCC | 18669648 | ||
| 1552 | Phosphorylation | TKGGPPEPMLSRWPC CCCCCCCCCHHCCCC | 18669648 | ||
| 1555 | Phosphorylation | GPPEPMLSRWPCTSP CCCCCCHHCCCCCCC | 25627689 | ||
| 1560 | Phosphorylation | MLSRWPCTSPRHSRD CHHCCCCCCCCCCCC | 30266825 | ||
| 1561 | Phosphorylation | LSRWPCTSPRHSRDY HHCCCCCCCCCCCCH | 30266825 | ||
| 1565 | Phosphorylation | PCTSPRHSRDYVEGA CCCCCCCCCCHHCCC | 26091039 | ||
| 1568 | Phosphorylation | SPRHSRDYVEGARRP CCCCCCCHHCCCCCC | - | ||
| 1569 | Phosphorylation | PRHSRDYVEGARRPL CCCCCCHHCCCCCCC | 18669648 | ||
| 1573 | Phosphorylation | RDYVEGARRPLDSPL CCHHCCCCCCCCCCC | 18669648 | ||
| 1574 | Phosphorylation | DYVEGARRPLDSPLC CHHCCCCCCCCCCCC | 18669648 | ||
| 1578 | Phosphorylation | GARRPLDSPLCTSLG CCCCCCCCCCCHHHC | 25159151 | ||
| 1579 | Phosphorylation | ARRPLDSPLCTSLGF CCCCCCCCCCHHHCC | 18669648 | ||
| 1582 | Phosphorylation | PLDSPLCTSLGFASP CCCCCCCHHHCCCCC | 23403867 | ||
| 1583 | Phosphorylation | LDSPLCTSLGFASPL CCCCCCHHHCCCCCH | 23403867 | ||
| 1587 | Ubiquitination | LCTSLGFASPLHSLE CCHHHCCCCCHHHHH | 32015554 | ||
| 1588 | O-linked_Glycosylation | CTSLGFASPLHSLEM CHHHCCCCCHHHHHH | 30379171 | ||
| 1588 | Phosphorylation | CTSLGFASPLHSLEM CHHHCCCCCHHHHHH | 25159151 | ||
| 1592 | Phosphorylation | GFASPLHSLEMSKNL CCCCCHHHHHHHCCC | 23403867 | ||
| 1596 | Phosphorylation | PLHSLEMSKNLSDDM CHHHHHHHCCCCHHH | 23403867 | ||
| 1600 | Phosphorylation | LEMSKNLSDDMKEVA HHHHCCCCHHHHHHH | 21712546 | ||
| 1609 | Phosphorylation | DMKEVAFSVRNAICS HHHHHHHHHHHHHHC | - | ||
| 1616 | Phosphorylation | SVRNAICSGPGELQV HHHHHHHCCCCCEEE | 25159151 | ||
| 1652 | Phosphorylation | SVGLQTEALRGSGVT EEEEECHHHCCCCCC | 18669648 | ||
| 1656 | Phosphorylation | QTEALRGSGVTSSPH ECHHHCCCCCCCCCC | 21712546 | ||
| 1658 | Phosphorylation | EALRGSGVTSSPHKC HHHCCCCCCCCCCCC | 18669648 | ||
| 1659 | Phosphorylation | ALRGSGVTSSPHKCL HHCCCCCCCCCCCCC | 23312004 | ||
| 1660 | Phosphorylation | LRGSGVTSSPHKCLT HCCCCCCCCCCCCCC | 20068231 | ||
| 1661 | Phosphorylation | RGSGVTSSPHKCLTP CCCCCCCCCCCCCCC | 26055452 | ||
| 1666 | Phosphorylation | TSSPHKCLTPKAGGG CCCCCCCCCCCCCCC | 18669648 | ||
| 1667 | Phosphorylation | SSPHKCLTPKAGGGA CCCCCCCCCCCCCCC | 18669648 | ||
| 1670 | Phosphorylation | HKCLTPKAGGGATPV CCCCCCCCCCCCCCC | 18669648 | ||
| 1672 | Phosphorylation | CLTPKAGGGATPVSS CCCCCCCCCCCCCCC | 18669648 | ||
| 1674 | Phosphorylation | TPKAGGGATPVSSPS CCCCCCCCCCCCCCC | 18669648 | ||
| 1675 | Phosphorylation | PKAGGGATPVSSPSR CCCCCCCCCCCCCCC | 30266825 | ||
| 1678 | Phosphorylation | GGGATPVSSPSRSLR CCCCCCCCCCCCCHH | 30266825 | ||
| 1679 | Phosphorylation | GGATPVSSPSRSLRS CCCCCCCCCCCCHHH | 30266825 | ||
| 1681 | Phosphorylation | ATPVSSPSRSLRSRQ CCCCCCCCCCHHHCC | 30266825 | ||
| 1683 | Phosphorylation | PVSSPSRSLRSRQVA CCCCCCCCHHHCCHH | 25159151 | ||
| 1686 | Phosphorylation | SPSRSLRSRQVAPAI CCCCCHHHCCHHHHH | 20068231 | ||
| 1703 | Phosphorylation | VQAKFERTCCSPKYG HHHHHHHHCCCCCCC | 29514088 | ||
| 1706 | Phosphorylation | KFERTCCSPKYGSPK HHHHHCCCCCCCCCH | 22199227 | ||
| 1711 | Phosphorylation | CCSPKYGSPKLQRKP CCCCCCCCCHHHCCC | 22199227 | ||
| 1729 | Phosphorylation | ADQPNNRTSPGMAQK CCCCCCCCCCCHHCC | 22199227 | ||
| 1730 | Phosphorylation | DQPNNRTSPGMAQKG CCCCCCCCCCHHCCC | 22199227 | ||
| 1746 | Phosphorylation | SESAWARSTTTRESP CCCCCCCCCCCCCCC | 27174698 | ||
| 1747 | Phosphorylation | ESAWARSTTTRESPV CCCCCCCCCCCCCCC | 27174698 | ||
| 1748 | Phosphorylation | SAWARSTTTRESPVH CCCCCCCCCCCCCCC | 27174698 | ||
| 1749 | Phosphorylation | AWARSTTTRESPVHT CCCCCCCCCCCCCCC | 27174698 | ||
| 1752 | Phosphorylation | RSTTTRESPVHTTIN CCCCCCCCCCCCCCC | 25159151 | ||
| 1756 | Phosphorylation | TRESPVHTTINDGLS CCCCCCCCCCCCCHH | 27174698 | ||
| 1757 | Phosphorylation | RESPVHTTINDGLSS CCCCCCCCCCCCHHH | 25627689 | ||
| 1772 | Phosphorylation | LFNIIDHSPVVQDPF HHHHHCCCCCCCCHH | 25159151 | ||
| 1787 | Phosphorylation | QKGLRAGSRSRSAEP HHCCCCCCCCCCCCC | 28102081 | ||
| 1789 | Phosphorylation | GLRAGSRSRSAEPRP CCCCCCCCCCCCCCC | 23403867 | ||
| 1791 | Phosphorylation | RAGSRSRSAEPRPEL CCCCCCCCCCCCCCC | 29255136 | ||
| 1803 | Phosphorylation | PELGPGQETGTNSRG CCCCCCCCCCCCCCC | 18669648 | ||
| 1804 | Phosphorylation | ELGPGQETGTNSRGR CCCCCCCCCCCCCCC | 22167270 | ||
| 1805 | Phosphorylation | LGPGQETGTNSRGRS CCCCCCCCCCCCCCC | 18669648 | ||
| 1806 | Phosphorylation | GPGQETGTNSRGRSP CCCCCCCCCCCCCCC | 30266825 | ||
| 1808 | Phosphorylation | GQETGTNSRGRSPSP CCCCCCCCCCCCCCC | 30266825 | ||
| 1811 | Phosphorylation | TGTNSRGRSPSPIGV CCCCCCCCCCCCCCC | 18669648 | ||
| 1812 | Phosphorylation | GTNSRGRSPSPIGVG CCCCCCCCCCCCCCC | 22167270 | ||
| 1814 | Phosphorylation | NSRGRSPSPIGVGSE CCCCCCCCCCCCCHH | 22167270 | ||
| 1820 | Phosphorylation | PSPIGVGSEMCREEG CCCCCCCHHHCHHCC | 22167270 | ||
| 1822 | Phosphorylation | PIGVGSEMCREEGGE CCCCCHHHCHHCCCC | 18669648 | ||
| 1831 | Phosphorylation | REEGGEGTPVKQDLS HHCCCCCCCCCCCCC | 22167270 | ||
| 1838 | Phosphorylation | TPVKQDLSAPPGYTL CCCCCCCCCCCCCCC | 21945579 | ||
| 1843 | Phosphorylation | DLSAPPGYTLTENVA CCCCCCCCCCHHHHH | 21945579 | ||
| 1844 | Phosphorylation | LSAPPGYTLTENVAR CCCCCCCCCHHHHHH | 21945579 | ||
| 1846 | Phosphorylation | APPGYTLTENVARIL CCCCCCCHHHHHHHH | 21945579 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MTCL1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MTCL1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTCL1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MARK2_HUMAN | MARK2 | physical | 23902687 | |
| MTCL1_HUMAN | MTCL1 | physical | 23902687 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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