DGC6L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DGC6L_HUMAN
• UniProt AC: Q9BY27
• Protein Name: Protein DGCR6L
• Gene Name: DGCR6L
• Organism: Homo sapiens (Human).
• Sequence Length: 220
• Subcellular Localization: Nucleus . Predominantly nuclear.
• Protein Description: May play a role in neural crest cell migration into the third and fourth pharyngeal pouches..
• Protein Sequence: MERYAAALEEVADGARQQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQALRQKHQEAQQACRPHNLPVVQAAQQRELEAVEHRIREEQRAMDQKIILELDRKVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQRGCRAGNAALGLGGPWQSPAAQCDQKGSPVPP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	ARQQERHYQLLSALQ HHHHHHHHHHHHHHH	13.69	-
99	Ubiquitination	LRQALRQKHQEAQQA HHHHHHHHHHHHHHH	40.60	-
140	Ubiquitination	EQRAMDQKIILELDR HHHHHHHHHHHHHHH	27.70	-
148	Ubiquitination	IILELDRKVADQQST HHHHHHHHHHHHHHH	41.25	29967540
206	Phosphorylation	GLGGPWQSPAAQCDQ CCCCCCCCCCHHCCC	16.79	28555341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DGC6L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DGC6L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DGC6L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCNRG_HUMAN	KCNRG	physical	16189514
RIM3A_HUMAN	RIMBP3	physical	25416956
DEUP1_HUMAN	CCDC67	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.