ZN774_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN774_HUMAN
• UniProt AC: Q6NX45
• Protein Name: Zinc finger protein 774
• Gene Name: ZNF774
• Organism: Homo sapiens (Human).
• Sequence Length: 483
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MWLGTSGKSGLPGHCLENPLQECHPAQLEEWALKGISRPSVISQPEQKEEPWVLPLQNFEARKIPRESHTDCEHQVAKLNQDNSETAEQCGTSSERTNKDLSHTLSWGGNWEQGLELEGQHGTLPGEGQLESFSQERDLNKLLDGYVGEKPMCAECGKSFNQSSYLIRHLRTHTGERPYTCIECGKGFKQSSDLVTHRRTHTGEKPYQCKGCEKKFSDSSTLIKHQRTHTGERPYECPECGKTFGRKPHLIMHQRTHTGEKPYACLECHKSFSRSSNFITHQRTHTGVKPYRCNDCGESFSQSSDLIKHQRTHTGERPFKCPECGKGFRDSSHFVAHMSTHSGERPFSCPDCHKSFSQSSHLVTHQRTHTGERPFKCENCGKGFADSSALIKHQRIHTGERPYKCGECGKSFNQSSHFITHQRIHLGDRPYRCPECGKTFNQRSHFLTHQRTHTGEKPFHCSKCNKSFRQKAHLLCHQNTHLI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	ISRPSVISQPEQKEE CCCCHHCCCCCCCCC	37.21	-
70	Phosphorylation	KIPRESHTDCEHQVA CCCCCCCCCHHHHHH	52.18	-
84	Phosphorylation	AKLNQDNSETAEQCG HHHHCCCHHHHHHHC	44.61	-
86	Phosphorylation	LNQDNSETAEQCGTS HHCCCHHHHHHHCCC	35.00	-
200	Phosphorylation	DLVTHRRTHTGEKPY CCEECCCCCCCCCCC	24.60	-
202	Phosphorylation	VTHRRTHTGEKPYQC EECCCCCCCCCCCCC	46.56	-
256	Phosphorylation	HLIMHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	-
258	Phosphorylation	IMHQRTHTGEKPYAC EEEECCCCCCCCEEE	46.56	-
273	Phosphorylation	LECHKSFSRSSNFIT EHHHHHHCCCCCCCE	38.04	17081983
312	Phosphorylation	DLIKHQRTHTGERPF HHHHHCCCCCCCCCC	19.74	28555341
314	Phosphorylation	IKHQRTHTGERPFKC HHHCCCCCCCCCCCC	39.87	25159151
320	Sumoylation	HTGERPFKCPECGKG CCCCCCCCCCCCCCC	52.11	-
320	Sumoylation	HTGERPFKCPECGKG CCCCCCCCCCCCCCC	52.11	-
368	Phosphorylation	HLVTHQRTHTGERPF CCEEECCCCCCCCCE	19.74	28555341
370	Phosphorylation	VTHQRTHTGERPFKC EEECCCCCCCCCEEC	39.87	26270265
398	Phosphorylation	IKHQRIHTGERPYKC HHCCCCCCCCCCEEC	38.06	24719451
404	Sumoylation	HTGERPYKCGECGKS CCCCCCEECCCCCCC	38.15	-
404	Sumoylation	HTGERPYKCGECGKS CCCCCCEECCCCCCC	38.15	-
452	Phosphorylation	HFLTHQRTHTGEKPF HCHHCCCCCCCCCCC	19.74	-
454	Phosphorylation	LTHQRTHTGEKPFHC HHCCCCCCCCCCCCC	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN774_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN774_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN774_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN774_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.