F90A1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F90A1_HUMAN
• UniProt AC: Q86YD7
• Protein Name: Protein FAM90A1
• Gene Name: FAM90A1
• Organism: Homo sapiens (Human).
• Sequence Length: 464
• Protein Sequence: MMARRDPKPGAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCEAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENLKPWKPQVEANPGPLNKDKGEKEERPRPQDPQRKALLHIFSRKPPEKPLPNQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHSSPAGGCREVPQAASKTHGLLQAVSPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRSAPAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPRTSPQTGTRTPAQVLSGDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLTAPSFHSPEKPGAFLAQSPHVSEKSEGPCVRVPPSVLYEDLQVPSSSEDSDSDLE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
79	Ubiquitination	NFGEKEGKENLKPWK CCCCCCCHHHCCCCC	44.51	32015554
137	Phosphorylation	LPNQKGSTESSDYLR CCCCCCCCCCCCCEE	48.86	24719451
139	Phosphorylation	NQKGSTESSDYLRVA CCCCCCCCCCCEEEC	28.70	24719451
142	Phosphorylation	GSTESSDYLRVASGP CCCCCCCCEEECCCC	9.80	24719451
155	Phosphorylation	GPMPVHTTSKRPRVD CCCCCCCCCCCCCCC	19.85	-
156	Phosphorylation	PMPVHTTSKRPRVDP CCCCCCCCCCCCCCC	28.02	-
171	Phosphorylation	VLSDRSATEMSDRGS CCCCCCCCCCCCHHC	33.20	28787133
174	Phosphorylation	DRSATEMSDRGSVLA CCCCCCCCCHHCHHH	20.23	-
182	Phosphorylation	DRGSVLASLSPLRKA CHHCHHHHCCHHHHH	25.81	23403867
184	Phosphorylation	GSVLASLSPLRKASL HCHHHHCCHHHHHHC	21.28	21815630
190	Phosphorylation	LSPLRKASLSSSSSL CCHHHHHHCCCCCCC	31.64	21964256
192	Phosphorylation	PLRKASLSSSSSLGP HHHHHHCCCCCCCCH	26.19	21964256
193	Phosphorylation	LRKASLSSSSSLGPK HHHHHCCCCCCCCHH	39.26	21964256
194	Phosphorylation	RKASLSSSSSLGPKE HHHHCCCCCCCCHHH	22.14	21964256
195	Phosphorylation	KASLSSSSSLGPKER HHHCCCCCCCCHHHH	31.37	23612710
204	Phosphorylation	LGPKERQTGAAADIP CCHHHHCCCCCCCCC	34.70	-
282	Phosphorylation	THSLGLGSNLSFGPG CCCCCCCCCCCCCCC	39.37	-
306	Acetylation	QACLNFPKKPRLGPF HHHCCCCCCCCCCCC	71.87	7406579

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F90A1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F90A1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F90A1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
CEP55_HUMAN	CEP55	physical	25416956
CEP72_HUMAN	CEP72	physical	25416956
GOPC_HUMAN	GOPC	physical	25416956
RINT1_HUMAN	RINT1	physical	25416956
GNPTA_HUMAN	GNPTAB	physical	25416956
CEP76_HUMAN	CEP76	physical	25416956
FSD2_HUMAN	FSD2	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
KASH5_HUMAN	CCDC155	physical	25416956
STAC3_HUMAN	STAC3	physical	25416956
CCD57_HUMAN	CCDC57	physical	25416956
FLNA_HUMAN	FLNA	physical	26186194
BRD4_HUMAN	BRD4	physical	26186194
BRD2_HUMAN	BRD2	physical	26186194
BRD3_HUMAN	BRD3	physical	26186194
RFPLB_HUMAN	RFPL4B	physical	26186194
SNX5_HUMAN	SNX5	physical	26186194
KDM5B_HUMAN	KDM5B	physical	26186194
MTMRE_HUMAN	MTMR14	physical	26186194
SNX1_HUMAN	SNX1	physical	26186194
SNX2_HUMAN	SNX2	physical	26186194
SUFU_HUMAN	SUFU	physical	26186194
WRP73_HUMAN	WRAP73	physical	26186194
RFPLA_HUMAN	RFPL4A	physical	26186194
TRAF4_HUMAN	TRAF4	physical	21516116
BRD3_HUMAN	BRD3	physical	28514442
BRD4_HUMAN	BRD4	physical	28514442
BRD2_HUMAN	BRD2	physical	28514442
KDM5B_HUMAN	KDM5B	physical	28514442
RFPLA_HUMAN	RFPL4A	physical	28514442
MTMRE_HUMAN	MTMR14	physical	28514442
FLNA_HUMAN	FLNA	physical	28514442
RFPLB_HUMAN	RFPL4B	physical	28514442
SNX1_HUMAN	SNX1	physical	28514442
SUFU_HUMAN	SUFU	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.