RFPLA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RFPLA_HUMAN
• UniProt AC: A6NLU0
• Protein Name: Ret finger protein-like 4A
• Gene Name: RFPL4A
• Organism: Homo sapiens (Human).
• Sequence Length: 287
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Sequence: MAEHFKQIIRCPVCLKDLEEAVQLKCGYACCLQCLNSLQKEPDGEGLLCRFCSVVSQKDDIKPKYKLRALVSIIKELEPKLKSVLTMNPRMRKFQVDMTFDVDTANNYLIISEDLRSFRSGDLSQNRKEQAERFDTALCVLGTPRFTSGRHYWEVDVGTSQVWDVGVCKESVNRQGKIVLSSEHGFLTVGCREGKVFAASTVPMTPLWVSPQLHRVGIFLDVGMRSIAFYNVSDGCHIYTFIEIPVCEPWRPFFAHKRGSQDDQSILSICSVINPSAASAPVSSEGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Ubiquitination	--MAEHFKQIIRCPV --CHHHHHHHHCCCC	42.36	23000965
63	Ubiquitination	SQKDDIKPKYKLRAL ECCCCCCCHHHHHHH	45.61	23000965
72	Phosphorylation	YKLRALVSIIKELEP HHHHHHHHHHHHHCH	21.32	24719451
83	Phosphorylation	ELEPKLKSVLTMNPR HHCHHHHHHHHCCHH	32.56	-
112	Phosphorylation	ANNYLIISEDLRSFR CCCEEEECCCHHHHH	20.33	23186163
188	Phosphorylation	SSEHGFLTVGCREGK EECCCEEEEEECCCC	16.76	27732954
260	Phosphorylation	FFAHKRGSQDDQSIL CCCCCCCCCCHHHHH	34.17	22468782
279	Phosphorylation	VINPSAASAPVSSEG CCCCCCCCCCCCCCC	32.59	22468782

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RFPLA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RFPLA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RFPLA_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RFPLA_HUMAN	RFPL4A	physical	16364311

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.