PTCD2_HUMAN - dbPTM
PTCD2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PTCD2_HUMAN
UniProt AC Q8WV60
Protein Name Pentatricopeptide repeat-containing protein 2, mitochondrial
Gene Name PTCD2
Organism Homo sapiens (Human).
Sequence Length 388
Subcellular Localization Mitochondrion .
Protein Description Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function..
Protein Sequence MVRDSMAAAFRPSNRVLLQALQILVYPGVGGSGSVSCRCPLGAKRYLLTDNVVKLKEFQQKKVAVACNLSGTKETYFRNLKKKLTQNKLILKGELITLLHLCESRDHVELAKNVIYRYHAENKNFTLGEYKFGPLFVRLCYELDLEESAVELMKDQHLRGFFSDSTSFNILMDMLFIKGKYKSALQVLIEMKNQDVKFTKDTYVLAFAICYKLNSPESFKICTTLREEALLKGEILSRRASCFAVALALNQNEMAKAVSIFSQIMNPESIACINLNIIIHIQSNMLENLIKTLKNAAEGNLSKFVKRHVFSEEVLAKVREKVKDVPALVAKFDEIYGTLHITGQVTTDSLDAVLCHTPRDRKSHTLLLNKRMVSRRTFQPLSQSLLAE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
26PhosphorylationQALQILVYPGVGGSG
HHHEEHHCCCCCCCC		7.2724043423
32PhosphorylationVYPGVGGSGSVSCRC
HCCCCCCCCCEECCC		23.2024043423
34PhosphorylationPGVGGSGSVSCRCPL
CCCCCCCCEECCCCC		16.7424043423
36PhosphorylationVGGSGSVSCRCPLGA
CCCCCCEECCCCCCC		9.5024043423
112UbiquitinationRDHVELAKNVIYRYH
CCHHHHHHHHHHHEE		65.4621890473
123UbiquitinationYRYHAENKNFTLGEY
HHEECCCCCEECCEE		44.9721890473
181PhosphorylationMLFIKGKYKSALQVL
HHHHCCCHHHHHHHH		20.8824719451
183PhosphorylationFIKGKYKSALQVLIE
HHCCCHHHHHHHHHH		30.9924719451
212UbiquitinationLAFAICYKLNSPESF
HHHHHHHHCCCHHHC		36.46-
223PhosphorylationPESFKICTTLREEAL
HHHCCCCHHHCHHHH		32.1324719451
224PhosphorylationESFKICTTLREEALL
HHCCCCHHHCHHHHH		21.2924719451
237PhosphorylationLLKGEILSRRASCFA
HHCCCHHHHHHHHHH		25.9424719451
259PhosphorylationNEMAKAVSIFSQIMN
HHHHHHHHHHHHHCC		23.8327174698
262PhosphorylationAKAVSIFSQIMNPES
HHHHHHHHHHCCHHH		19.6827174698
269PhosphorylationSQIMNPESIACINLN
HHHCCHHHCEEEEEC		19.4227174698
283PhosphorylationNIIIHIQSNMLENLI
CEEEECCCCHHHHHH		24.4927174698
294MalonylationENLIKTLKNAAEGNL
HHHHHHHHHHHHCCH		50.1732601280
363PhosphorylationHTPRDRKSHTLLLNK
CCCCCCCCCEEEECC		23.6919664994
365PhosphorylationPRDRKSHTLLLNKRM
CCCCCCCEEEECCCC		26.6219664994
382PhosphorylationRRTFQPLSQSLLAE-
HHCCCCHHHHHHCC-		25.1414702039
384PhosphorylationTFQPLSQSLLAE---
CCCCHHHHHHCC---		23.2123917254
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PTCD2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PTCD2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PTCD2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PTCD2_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PTCD2_HUMAN

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Related Literatures of Post-Translational Modification

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