SOX15_HUMAN - dbPTM
SOX15_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SOX15_HUMAN
UniProt AC O60248
Protein Name Protein SOX-15
Gene Name SOX15
Organism Homo sapiens (Human).
Sequence Length 233
Subcellular Localization Nucleus .
Protein Description Binds to the 5'-AACAAT-3' sequence..
Protein Sequence MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MALPGSSQDQAWSL
-CCCCCCCCCCCCCC
43.6324719451
37PhosphorylationQEREGAGSPAAPGTL
CCCCCCCCCCCCCCC
15.7219664994
43PhosphorylationGSPAAPGTLPLEKVK
CCCCCCCCCCHHHCC
24.9223927012
60PhosphorylationMNAFMVWSSAQRRQM
CEEHHHHHHHHHHHH
12.3724043423
61PhosphorylationNAFMVWSSAQRRQMA
EEHHHHHHHHHHHHH
16.8324043423
77PhosphorylationQNPKMHNSEISKRLG
HCCCCCHHHHHHHHC
22.9429759185
80PhosphorylationKMHNSEISKRLGAQW
CCCHHHHHHHHCCHH
13.9929759185
113PhosphorylationRARHLRDYPDYKYRP
HHHHHCCCCCCCCCC
7.5028387310
116PhosphorylationHLRDYPDYKYRPRRK
HHCCCCCCCCCCCCC
12.86-
169PhosphorylationGYRPPSYSTAYLPGS
CCCCCCCCEEECCCC
15.7630576142
172PhosphorylationPPSYSTAYLPGSYGS
CCCCCEEECCCCCCC
17.3327642862
176PhosphorylationSTAYLPGSYGSSHCK
CEEECCCCCCCCCCE
25.1230576142
177PhosphorylationTAYLPGSYGSSHCKL
EEECCCCCCCCCCEE
27.2630576142
188PhosphorylationHCKLEAPSPCSLPQS
CCEECCCCCCCCCCC
45.6625394399
191PhosphorylationLEAPSPCSLPQSDPR
ECCCCCCCCCCCCCC
46.6027794612
195PhosphorylationSPCSLPQSDPRLQGE
CCCCCCCCCCCCCCC
47.8727794612
206PhosphorylationLQGELLPTYTHYLPP
CCCCCCCCCCCCCCC
40.8123090842
207PhosphorylationQGELLPTYTHYLPPG
CCCCCCCCCCCCCCC
6.9223090842
208PhosphorylationGELLPTYTHYLPPGS
CCCCCCCCCCCCCCC
13.4123090842
210PhosphorylationLLPTYTHYLPPGSPT
CCCCCCCCCCCCCCC
17.0727251275
215PhosphorylationTHYLPPGSPTPYNPP
CCCCCCCCCCCCCCC
31.2323090842
217PhosphorylationYLPPGSPTPYNPPLA
CCCCCCCCCCCCCCC
39.8523090842
219PhosphorylationPPGSPTPYNPPLAGA
CCCCCCCCCCCCCCC
42.6625394399

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SOX15_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SOX15_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SOX15_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BHE40_HUMANBHLHE40physical
25416956
HSFY1_HUMANHSFY1physical
25416956

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SOX15_HUMAN

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Related Literatures of Post-Translational Modification

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