HSFY1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HSFY1_HUMAN
• UniProt AC: Q96LI6
• Protein Name: Heat shock transcription factor, Y-linked
• Gene Name: HSFY1
• Organism: Homo sapiens (Human).
• Sequence Length: 401
• Subcellular Localization: Nucleus . Cytoplasm .
• Protein Sequence: MAHVSSETQDVSPKDELTASEASTRSPLCEHTFPGDSDLRSMIEEHAFQVLSQGSLLESPSYTVCVSEPDKDDDFLSLNFPRKLWKIVESDQFKSISWDENGTCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQLNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRIGVKNASPISTLFNEDFNKKHFRAGANMENHNSALAAEASEESLFSASKNLNMPLTRESSVRQIIANSSVPIRSGFPPPSPSTSVGPSEQIATDQHAILNQLTTIHMHSHSTYMQARGHIVNFITTTTSQYHIISPLQNGYFGLTVEPSAVPTRYPLVSVNEAPYRNMLPAGNPWLQMPTIADRSAAPHSRLALQPSPLDKYHPNYN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Acetylation	ETQDVSPKDELTASE CCCCCCHHHHCCHHH	57.22	25038526
95	Phosphorylation	VESDQFKSISWDENG HCCCCCCCCEECCCC	24.12	28842319
97	Phosphorylation	SDQFKSISWDENGTC CCCCCCCEECCCCCE	35.25	28842319
175	Phosphorylation	VLSKLKFYYNPNFKR HHHHHEEEECCCCCC	10.76	19658100
176	Phosphorylation	LSKLKFYYNPNFKRG HHHHEEEECCCCCCC	27.55	19658100
180 (in isoform 2)	Phosphorylation	-	6.35	30206219
181	Acetylation	FYYNPNFKRGYPQLL EEECCCCCCCCCHHH	52.10	25038526
182 (in isoform 2)	Phosphorylation	-	45.82	30206219
183 (in isoform 2)	Phosphorylation	-	38.78	30206219
184 (in isoform 2)	Phosphorylation	-	7.58	30206219
185 (in isoform 2)	Phosphorylation	-	22.59	30206219
201	Phosphorylation	RIGVKNASPISTLFN HHCCCCCCCCHHHCC	31.96	30622161
204	Phosphorylation	VKNASPISTLFNEDF CCCCCCCHHHCCCCC	23.57	30622161
205	Phosphorylation	KNASPISTLFNEDFN CCCCCCHHHCCCCCC	35.77	30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HSFY1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HSFY1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HSFY1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
E2F7_HUMAN	E2F7	physical	25036637
NDUS1_HUMAN	NDUFS1	physical	25036637
PPM1A_HUMAN	PPM1A	physical	25036637
AIF1_HUMAN	AIF1	physical	25036637
RABE1_HUMAN	RABEP1	physical	25036637
TBA3C_HUMAN	TUBA3C	physical	28514442
SATB2_HUMAN	SATB2	physical	28514442
POTEF_HUMAN	POTEF	physical	28514442
CHD4_HUMAN	CHD4	physical	28514442
CHD3_HUMAN	CHD3	physical	28514442
MIS12_HUMAN	MIS12	physical	28514442
NDUS1_HUMAN	NDUFS1	physical	28514442
RAD51_HUMAN	RAD51	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.