| UniProt ID | BARX1_HUMAN | |
|---|---|---|
| UniProt AC | Q9HBU1 | |
| Protein Name | Homeobox protein BarH-like 1 | |
| Gene Name | BARX1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 254 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.. | |
| Protein Sequence | MQRPGEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKDAEKPAEVPGEPSDRSRED | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 126 | Acetylation | LELQLRGKLEAAGPG EEEEECCEEECCCCC | 36.40 | 26051181 | |
| 150 | Phosphorylation | RRSRTVFTELQLMGL CCCCCHHHHHHHCCH | 31.30 | 26074081 | |
| 169 | Phosphorylation | EKQKYLSTPDRIDLA HHHCCCCCCCHHHHH | 26.98 | 28387310 | |
| 209 | Phosphorylation | LQGGGLESPTKPKGR EECCCCCCCCCCCCC | 42.80 | 28450419 | |
| 211 | Phosphorylation | GGGLESPTKPKGRPK CCCCCCCCCCCCCCC | 70.07 | 28450419 | |
| 212 | Acetylation | GGLESPTKPKGRPKK CCCCCCCCCCCCCCC | 48.38 | 26051181 | |
| 221 | Phosphorylation | KGRPKKNSIPTSEQL CCCCCCCCCCCHHHH | 38.53 | 26657352 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BARX1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BARX1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BARX1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CP17A_HUMAN | CYP17A1 | physical | 21988832 | |
| HXD9_HUMAN | HOXD9 | physical | 21988832 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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