MARF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MARF1_HUMAN
• UniProt AC: Q9Y4F3
• Protein Name: Meiosis regulator and mRNA stability factor 1 {ECO:0000312|HGNC:HGNC:29562}
• Gene Name: MARF1 {ECO:0000312|HGNC:HGNC:29562}
• Organism: Homo sapiens (Human).
• Sequence Length: 1742
• Subcellular Localization: Peroxisome .
• Protein Description: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity)..
• Protein Sequence: MMEGNGTENSCSRTRGWLQQDNDAKPWLWKFSNCFSRPEQTLPHSPQTKEYMENKKVAVELKDVPSPLHAGSKLFPAVPLPDIRSLQQPKIQLSSVPKVSCCAHCPNEPSTSPMRFGGGGGGSGGTSSLIHPGALLDSQSTRTITCQVGSGFAFQSASSLQNASARNNLAGIASDFPSMCLESNLSSCKHLPCCGKLHFQSCHGNVHKLHQFPSLQGCTSAGYFPCSDFTSGAPGHLEEHISQSELTPHLCTNSLHLNVVPPVCLKGSLYCEDCLNKPARNSIIDAAKVWPNIPPPNTQPAPLAVPLCNGCGTKGTGKETTLLLATSLGKAASKFGSPEVAVAGQVLENLPPIGVFWDIENCSVPSGRSATAVVQRIREKFFKGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANELIRFEEFISDLPPRLPLKMPQCHTLLYVYNLPANKDGKSVSNRLRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENEDVFGNRIIVSFTPKNRELCETKSSNAIADKVKSPKKLKNPKLCLIKDASEQSSSAKATPGKGSQANSGSATKNTNVKSLQELCRMESKTGHRNSEHQQGHLRLVVPTHGNSSAAVSTPKNSGVAEPVYKTSQKKENLSARSVTSSPVEKKDKEETVFQVSYPSAFSKLVASRQVSPLLASQSWSSRSMSPNLLNRASPLAFNIANSSSEADCPDPFANGADVQVSNIDYRLSRKELQQLLQEAFARHGKVKSVELSPHTDYQLKAVVQMENLQDAIGAVNSLHRYKIGSKKILVSLATGAASKSLSLLSAETMSVLQDAPACCLPLFKFTDIYEKKFGHKLNVSDLYKLTDTVAIREQGNGRLVCLLPSSQARQSPLGSSQSHDGSSTNCSPIIFEELEYHEPVCRQHCSNKDFSEHEFDPDSYKIPFVILSLKTFAPQVHSLLQTHEGTVPLLSFPDCYIAEFGDLEVVQENQGGVPLEHFITCVPGVNIATAQNGIKVVKWIHNKPPPPNTDPWLLRSKSPVGNPQLIQFSREVIDLLKSQPSCVIPISHFIPSYHHHFAKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLLTLTHRAQVKRFTQDLLKLLKSQASKQVIVREFSQAYHWCFSKDWDVTEYGVCELIDIVSEIPDTTICLSQQDNEMVICIPKRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELFEAIPDTLQVLECGEEKILTLTEVERFKALAAQFVKLLRSQKDNCLMMTDLLTEYAKTFGYTFRLQDYDVSSISALTQKLCHVVKVADIESGRQIQLINRKSLRSLTAQLLVLLMSWEGTTHLSVEELKRHYESTHNTPLNPCEYGFMTLTELLKSLPYLVEVFTNDKMEECVKLTSLYLFAKNVRSLLHTYHYQQIFLHEFSMAYTKYVGETLQPKTYGHSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKSRLSSLSLSPANHENQPSEGERILEVPESHTASELKLGADGSGPSHTEQELLRLTDDSPVDLLCAPVPSCLPSPQLRPDPVILQSADLIQFEERPQEPSEIMILNQEEKMEIPIPGKSKTLTSDSSSSCISAAVPVPPCPSSETSESLLSKDPVESPAKKQPKNRVKLAANFSLAPITKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MMEGNGTENSCSRT -CCCCCCCCCCCCCC	35.67	25690035
10	Phosphorylation	EGNGTENSCSRTRGW CCCCCCCCCCCCCCC	13.77	25690035
25	Ubiquitination	LQQDNDAKPWLWKFS HHCCCCCCCCHHHCC	39.32	29967540
36	Phosphorylation	WKFSNCFSRPEQTLP HHCCCCCCCCHHCCC	49.48	28555341
45	Phosphorylation	PEQTLPHSPQTKEYM CHHCCCCCHHHHHHH	19.43	25159151
48	Phosphorylation	TLPHSPQTKEYMENK CCCCCHHHHHHHHCC	29.27	-
56	Ubiquitination	KEYMENKKVAVELKD HHHHHCCCEEEEECC	47.19	29967540
62	Acetylation	KKVAVELKDVPSPLH CCEEEEECCCCCCCC	43.08	30589675
62	Ubiquitination	KKVAVELKDVPSPLH CCEEEEECCCCCCCC	43.08	29967540
66	Phosphorylation	VELKDVPSPLHAGSK EEECCCCCCCCCCCC	39.68	25159151
72	Phosphorylation	PSPLHAGSKLFPAVP CCCCCCCCCCCCCCC	27.28	23403867
73	Acetylation	SPLHAGSKLFPAVPL CCCCCCCCCCCCCCC	53.91	25953088
73	Ubiquitination	SPLHAGSKLFPAVPL CCCCCCCCCCCCCCC	53.91	23503661
73 (in isoform 3)	Ubiquitination	-	53.91	-
89 (in isoform 3)	Ubiquitination	-	23.82	21906983
90	Ubiquitination	IRSLQQPKIQLSSVP HHHCCCCCEECCCCC	38.45	22817900
90 (in isoform 1)	Ubiquitination	-	38.45	21906983
98	Ubiquitination	IQLSSVPKVSCCAHC EECCCCCCEEEECCC	44.62	29967540
110	Phosphorylation	AHCPNEPSTSPMRFG CCCCCCCCCCCCCCC	35.03	28348404
111	Phosphorylation	HCPNEPSTSPMRFGG CCCCCCCCCCCCCCC	47.79	25159151
112	Phosphorylation	CPNEPSTSPMRFGGG CCCCCCCCCCCCCCC	22.49	25159151
135	Ubiquitination	SLIHPGALLDSQSTR CCCCCCCEECCCCCC	7.28	23503661
139	Ubiquitination	PGALLDSQSTRTITC CCCEECCCCCCEEEE	48.79	23503661
151	Ubiquitination	ITCQVGSGFAFQSAS EEEEECCCCCCCCHH	16.39	23503661
155	Ubiquitination	VGSGFAFQSASSLQN ECCCCCCCCHHHHCC	34.36	23503661
189	Ubiquitination	ESNLSSCKHLPCCGK HCCCCCCCCCCCCCE	50.56	-
196	Ubiquitination	KHLPCCGKLHFQSCH CCCCCCCEEEEECCC	25.52	-
277	Ubiquitination	YCEDCLNKPARNSII EEHHHCCCCCCCCCC	27.40	22505724
282	Phosphorylation	LNKPARNSIIDAAKV CCCCCCCCCCHHHHH	18.50	24719451
288	Ubiquitination	NSIIDAAKVWPNIPP CCCCHHHHHCCCCCC	46.70	-
298	Phosphorylation	PNIPPPNTQPAPLAV CCCCCCCCCCCCCCC	41.52	22210691
313	Phosphorylation	PLCNGCGTKGTGKET EECCCCCCCCCCHHH	30.31	22210691
314	Ubiquitination	LCNGCGTKGTGKETT ECCCCCCCCCCHHHH	39.50	23503661
316	Phosphorylation	NGCGTKGTGKETTLL CCCCCCCCCHHHHHH	46.79	28387310
318	Ubiquitination	CGTKGTGKETTLLLA CCCCCCCHHHHHHHH	52.29	23503661
318 (in isoform 3)	Ubiquitination	-	52.29	-
326	Phosphorylation	ETTLLLATSLGKAAS HHHHHHHHHHHHHHH	25.18	22210691
327	Phosphorylation	TTLLLATSLGKAASK HHHHHHHHHHHHHHH	29.53	22210691
330	Ubiquitination	LLATSLGKAASKFGS HHHHHHHHHHHHHCC	46.18	23503661
330 (in isoform 3)	Ubiquitination	-	46.18	-
334	Ubiquitination	SLGKAASKFGSPEVA HHHHHHHHHCCHHHH	49.36	23503661
380	Ubiquitination	VVQRIREKFFKGHRE HHHHHHHHHHCCCCC	46.37	-
395	Ubiquitination	AEFICVCDISKENKE EEEEEEEECCHHHHH	28.00	29967540
398	Ubiquitination	ICVCDISKENKEVIQ EEEEECCHHHHHHHH	66.69	29967540
401	Ubiquitination	CDISKENKEVIQELN EECCHHHHHHHHHHH	55.22	29967540
406	Ubiquitination	ENKEVIQELNNCQVT HHHHHHHHHHCCEEE	42.20	27667366
419	Ubiquitination	VTVAHINATAKNAAD EEEEEEHHCCCCCCC	14.34	29967540
422	Ubiquitination	AHINATAKNAADDKL EEEHHCCCCCCCHHH	42.64	29967540
432	Phosphorylation	ADDKLRQSLRRFANT CCHHHHHHHHHHHHC	19.87	29496963
460	Phosphorylation	VNFALELSDLRHRHG CCHHHHHHHCCHHCC	25.81	24719451
536	Phosphorylation	SNRLRRLSDNCGGKV HHHHHHHHCCCCCCE	25.60	-
542	Ubiquitination	LSDNCGGKVLSITGC HHCCCCCCEEEEECH	25.86	-
582	Phosphorylation	GNRIIVSFTPKNREL CCEEEEECCCCCHHH	10.57	17081983
582	Ubiquitination	GNRIIVSFTPKNREL CCEEEEECCCCCHHH	10.57	27667366
583	Phosphorylation	NRIIVSFTPKNRELC CEEEEECCCCCHHHH	26.33	22817900
584	Ubiquitination	RIIVSFTPKNRELCE EEEEECCCCCHHHHC	29.88	27667366
585	Malonylation	IIVSFTPKNRELCET EEEECCCCCHHHHCC	66.63	26320211
585	Ubiquitination	IIVSFTPKNRELCET EEEECCCCCHHHHCC	66.63	27667366
585 (in isoform 3)	Ubiquitination	-	66.63	-
590	Ubiquitination	TPKNRELCETKSSNA CCCCHHHHCCCCCCH	5.52	29967540
592	Ubiquitination	KNRELCETKSSNAIA CCHHHHCCCCCCHHH	34.92	29967540
593	Ubiquitination	NRELCETKSSNAIAD CHHHHCCCCCCHHHH	29.59	29967540
594	Phosphorylation	RELCETKSSNAIADK HHHHCCCCCCHHHHH	35.92	23312004
595	Phosphorylation	ELCETKSSNAIADKV HHHCCCCCCHHHHHC	31.66	23312004
604	Phosphorylation	AIADKVKSPKKLKNP HHHHHCCCCHHCCCC	44.96	23927012
614	Ubiquitination	KLKNPKLCLIKDASE HCCCCCEEEEECCCC	4.63	29967540
616	Ubiquitination	KNPKLCLIKDASEQS CCCCEEEEECCCCCC	3.56	29967540
617	Ubiquitination	NPKLCLIKDASEQSS CCCEEEEECCCCCCC	34.00	29967540
620	Phosphorylation	LCLIKDASEQSSSAK EEEEECCCCCCCCCC	46.43	-
629	Phosphorylation	QSSSAKATPGKGSQA CCCCCCCCCCCCCCC	31.69	30576142
629	Ubiquitination	QSSSAKATPGKGSQA CCCCCCCCCCCCCCC	31.69	29967540
631	Ubiquitination	SSAKATPGKGSQANS CCCCCCCCCCCCCCC	42.47	29967540
632	Ubiquitination	SAKATPGKGSQANSG CCCCCCCCCCCCCCC	57.50	29967540
638	Phosphorylation	GKGSQANSGSATKNT CCCCCCCCCCCCCCC	36.82	30576142
640	Phosphorylation	GSQANSGSATKNTNV CCCCCCCCCCCCCCH	32.36	30576142
640	Ubiquitination	GSQANSGSATKNTNV CCCCCCCCCCCCCCH	32.36	29967540
641	Ubiquitination	SQANSGSATKNTNVK CCCCCCCCCCCCCHH	26.56	23503661
642	Phosphorylation	QANSGSATKNTNVKS CCCCCCCCCCCCHHH	26.90	30576142
642	Ubiquitination	QANSGSATKNTNVKS CCCCCCCCCCCCHHH	26.90	23503661
643	Ubiquitination	ANSGSATKNTNVKSL CCCCCCCCCCCHHHH	62.58	23503661
644	Ubiquitination	NSGSATKNTNVKSLQ CCCCCCCCCCHHHHH	32.31	23503661
645	Ubiquitination	SGSATKNTNVKSLQE CCCCCCCCCHHHHHH	42.83	29967540
647	Ubiquitination	SATKNTNVKSLQELC CCCCCCCHHHHHHHH	4.13	29967540
648	Ubiquitination	ATKNTNVKSLQELCR CCCCCCHHHHHHHHH	47.74	29967540
649	Phosphorylation	TKNTNVKSLQELCRM CCCCCHHHHHHHHHH	30.88	27470641
658	Phosphorylation	QELCRMESKTGHRNS HHHHHHHCCCCCCCC	26.61	-
677	Ubiquitination	GHLRLVVPTHGNSSA CEEEEEEECCCCCCC	15.93	23503661
678	Ubiquitination	HLRLVVPTHGNSSAA EEEEEEECCCCCCCC	30.70	23503661
679	Ubiquitination	LRLVVPTHGNSSAAV EEEEEECCCCCCCCC	27.63	23503661
680	Ubiquitination	RLVVPTHGNSSAAVS EEEEECCCCCCCCCC	37.89	23503661
686	Phosphorylation	HGNSSAAVSTPKNSG CCCCCCCCCCCCCCC	7.00	24719451
687	Phosphorylation	GNSSAAVSTPKNSGV CCCCCCCCCCCCCCC	33.98	28857561
687	Ubiquitination	GNSSAAVSTPKNSGV CCCCCCCCCCCCCCC	33.98	29967540
688	Phosphorylation	NSSAAVSTPKNSGVA CCCCCCCCCCCCCCC	31.51	25159151
689	Ubiquitination	SSAAVSTPKNSGVAE CCCCCCCCCCCCCCC	26.73	29967540
690	Ubiquitination	SAAVSTPKNSGVAEP CCCCCCCCCCCCCCC	64.93	29967540
697	Ubiquitination	KNSGVAEPVYKTSQK CCCCCCCCCCCCCCC	25.63	29967540
699	Phosphorylation	SGVAEPVYKTSQKKE CCCCCCCCCCCCCCC	21.18	19702290
699	Ubiquitination	SGVAEPVYKTSQKKE CCCCCCCCCCCCCCC	21.18	29967540
700	Ubiquitination	GVAEPVYKTSQKKEN CCCCCCCCCCCCCCC	41.77	29967540
701	Phosphorylation	VAEPVYKTSQKKENL CCCCCCCCCCCCCCC	20.78	29214152
702	Phosphorylation	AEPVYKTSQKKENLS CCCCCCCCCCCCCCC	35.53	29214152
709	Phosphorylation	SQKKENLSARSVTSS CCCCCCCCCCCCCCC	32.97	30576142
711	Phosphorylation	KKENLSARSVTSSPV CCCCCCCCCCCCCCC	28.43	27251275
712	Phosphorylation	KENLSARSVTSSPVE CCCCCCCCCCCCCCC	29.48	25159151
714	Phosphorylation	NLSARSVTSSPVEKK CCCCCCCCCCCCCCC	25.41	23403867
715	Phosphorylation	LSARSVTSSPVEKKD CCCCCCCCCCCCCCC	30.41	25072903
716	Phosphorylation	SARSVTSSPVEKKDK CCCCCCCCCCCCCCC	24.49	25159151
717	Ubiquitination	ARSVTSSPVEKKDKE CCCCCCCCCCCCCCC	37.75	29967540
719	Ubiquitination	SVTSSPVEKKDKEET CCCCCCCCCCCCCCC	58.74	29967540
720	Ubiquitination	VTSSPVEKKDKEETV CCCCCCCCCCCCCCE	67.51	29967540
726	Phosphorylation	EKKDKEETVFQVSYP CCCCCCCCEEEEECH	27.93	28450419
731	Phosphorylation	EETVFQVSYPSAFSK CCCEEEEECHHHHHH	22.12	23312004
732	Phosphorylation	ETVFQVSYPSAFSKL CCEEEEECHHHHHHH	11.44	28450419
734	Phosphorylation	VFQVSYPSAFSKLVA EEEEECHHHHHHHHH	33.44	27762562
735	Ubiquitination	FQVSYPSAFSKLVAS EEEECHHHHHHHHHH	14.29	29967540
737	Phosphorylation	VSYPSAFSKLVASRQ EECHHHHHHHHHHCC	25.46	27762562
737	Ubiquitination	VSYPSAFSKLVASRQ EECHHHHHHHHHHCC	25.46	29967540
738	Ubiquitination	SYPSAFSKLVASRQV ECHHHHHHHHHHCCC	40.29	29967540
745	Phosphorylation	KLVASRQVSPLLASQ HHHHHCCCCHHHHCC	6.55	24719451
745 (in isoform 5)	Phosphorylation	-	6.55	24719451
746	Phosphorylation	LVASRQVSPLLASQS HHHHCCCCHHHHCCC	11.07	22199227
751	Phosphorylation	QVSPLLASQSWSSRS CCCHHHHCCCCCCCC	25.39	27080861
753	Phosphorylation	SPLLASQSWSSRSMS CHHHHCCCCCCCCCC	26.82	29083192
755	Phosphorylation	LLASQSWSSRSMSPN HHHCCCCCCCCCCHH	22.56	27080861
756	Phosphorylation	LASQSWSSRSMSPNL HHCCCCCCCCCCHHH	23.32	27080861
758	Phosphorylation	SQSWSSRSMSPNLLN CCCCCCCCCCHHHHH	26.09	23403867
760	Phosphorylation	SWSSRSMSPNLLNRA CCCCCCCCHHHHHHC	16.34	23401153
760 (in isoform 5)	Phosphorylation	-	16.34	24260401
767	Ubiquitination	SPNLLNRASPLAFNI CHHHHHHCCCHHHCC	17.90	23503661
768	Phosphorylation	PNLLNRASPLAFNIA HHHHHHCCCHHHCCC	19.74	27251275
768 (in isoform 5)	Phosphorylation	-	19.74	30131370
769	Ubiquitination	NLLNRASPLAFNIAN HHHHHCCCHHHCCCC	27.07	23503661
777	Phosphorylation	LAFNIANSSSEADCP HHHCCCCCCCCCCCC	26.64	27080861
778	Phosphorylation	AFNIANSSSEADCPD HHCCCCCCCCCCCCC	31.82	27080861
779	Phosphorylation	FNIANSSSEADCPDP HCCCCCCCCCCCCCC	36.30	27080861
802	Ubiquitination	VSNIDYRLSRKELQQ EHHCCHHCCHHHHHH	4.77	29967540
805	Ubiquitination	IDYRLSRKELQQLLQ CCHHCCHHHHHHHHH	60.44	29967540
811	Ubiquitination	RKELQQLLQEAFARH HHHHHHHHHHHHHHC	3.62	23503661
813	Ubiquitination	ELQQLLQEAFARHGK HHHHHHHHHHHHCCC	45.80	23503661
817	Ubiquitination	LLQEAFARHGKVKSV HHHHHHHHCCCCEEE	32.41	23503661
819	Ubiquitination	QEAFARHGKVKSVEL HHHHHHCCCCEEEEC	30.79	23503661
820	Ubiquitination	EAFARHGKVKSVELS HHHHHCCCCEEEECC	40.12	23503661
821	Ubiquitination	AFARHGKVKSVELSP HHHHCCCCEEEECCC	7.09	23503661
822	Ubiquitination	FARHGKVKSVELSPH HHHCCCCEEEECCCC	52.88	23503661
822 (in isoform 3)	Ubiquitination	-	52.88	-
823	Phosphorylation	ARHGKVKSVELSPHT HHCCCCEEEECCCCC	24.66	30624053
823	Ubiquitination	ARHGKVKSVELSPHT HHCCCCEEEECCCCC	24.66	23503661
827	Phosphorylation	KVKSVELSPHTDYQL CCEEEECCCCCCHHH	10.92	25159151
832	Ubiquitination	ELSPHTDYQLKAVVQ ECCCCCCHHHHHHHE	19.53	29967540
835	Ubiquitination	PHTDYQLKAVVQMEN CCCCHHHHHHHEECC	24.49	29967540
866	Phosphorylation	GSKKILVSLATGAAS CCCHHHHHHHHCHHH	14.61	29396449
869	Phosphorylation	KILVSLATGAASKSL HHHHHHHHCHHHHHH	32.42	20068231
873	Phosphorylation	SLATGAASKSLSLLS HHHHCHHHHHHHHHC	23.42	20068231
903	Ubiquitination	PLFKFTDIYEKKFGH EEEEECHHHHHHHCC	4.32	29967540
904	Ubiquitination	LFKFTDIYEKKFGHK EEEECHHHHHHHCCC	25.22	29967540
906	Ubiquitination	KFTDIYEKKFGHKLN EECHHHHHHHCCCCC	36.11	29967540
907	Ubiquitination	FTDIYEKKFGHKLNV ECHHHHHHHCCCCCH	44.64	29967540
908	Ubiquitination	TDIYEKKFGHKLNVS CHHHHHHHCCCCCHH	21.47	29967540
911	Ubiquitination	YEKKFGHKLNVSDLY HHHHHCCCCCHHHHH	41.98	29967540
913	Ubiquitination	KKFGHKLNVSDLYKL HHHCCCCCHHHHHHC	35.73	23503661
914	Phosphorylation	KFGHKLNVSDLYKLT HHCCCCCHHHHHHCC	7.35	17081983
914	Ubiquitination	KFGHKLNVSDLYKLT HHCCCCCHHHHHHCC	7.35	23503661
915	Phosphorylation	FGHKLNVSDLYKLTD HCCCCCHHHHHHCCC	22.33	17081983
916	Ubiquitination	GHKLNVSDLYKLTDT CCCCCHHHHHHCCCE	50.13	29967540
919	Ubiquitination	LNVSDLYKLTDTVAI CCHHHHHHCCCEEEE	52.81	29967540
946	Phosphorylation	PSSQARQSPLGSSQS ECHHCCCCCCCCCCC	19.28	26471730
949	Ubiquitination	QARQSPLGSSQSHDG HCCCCCCCCCCCCCC	28.74	23503661
950	Phosphorylation	ARQSPLGSSQSHDGS CCCCCCCCCCCCCCC	32.65	28122231
950	Ubiquitination	ARQSPLGSSQSHDGS CCCCCCCCCCCCCCC	32.65	23503661
951	Phosphorylation	RQSPLGSSQSHDGSS CCCCCCCCCCCCCCC	33.63	28122231
953	Phosphorylation	SPLGSSQSHDGSSTN CCCCCCCCCCCCCCC	26.03	28122231
957	Phosphorylation	SSQSHDGSSTNCSPI CCCCCCCCCCCCCCC	39.79	28122231
958	Phosphorylation	SQSHDGSSTNCSPII CCCCCCCCCCCCCCE	29.21	28122231
959	Phosphorylation	QSHDGSSTNCSPIIF CCCCCCCCCCCCCEE	41.77	28122231
962	Phosphorylation	DGSSTNCSPIIFEEL CCCCCCCCCCEEEHH	22.62	28348404
980	Ubiquitination	EPVCRQHCSNKDFSE CCHHHHHHCCCCCCC	3.47	29967540
983	Ubiquitination	CRQHCSNKDFSEHEF HHHHHCCCCCCCCCC	43.80	29967540
993	Ubiquitination	SEHEFDPDSYKIPFV CCCCCCCCCCCCCEE	67.45	29967540
996	Ubiquitination	EFDPDSYKIPFVILS CCCCCCCCCCEEEEE	48.10	29967540
1003	Phosphorylation	KIPFVILSLKTFAPQ CCCEEEEECCCCHHH	19.39	24719451
1032 (in isoform 3)	Phosphorylation	-	3.58	25849741
1033 (in isoform 3)	Ubiquitination	-	4.60	-
1034 (in isoform 3)	Phosphorylation	-	40.37	25849741
1039	Ubiquitination	IAEFGDLEVVQENQG EEECCCEEEEEECCC	45.44	23503661
1070	Ubiquitination	ATAQNGIKVVKWIHN ECCCCCCEEEEEHHC	42.23	29967540
1073	Ubiquitination	QNGIKVVKWIHNKPP CCCCEEEEEHHCCCC	43.34	29967540
1075	Ubiquitination	GIKVVKWIHNKPPPP CCEEEEEHHCCCCCC	1.81	29967540
1078	Ubiquitination	VVKWIHNKPPPPNTD EEEEHHCCCCCCCCC	44.75	29967540
1083	Ubiquitination	HNKPPPPNTDPWLLR HCCCCCCCCCCCHHC	63.99	23503661
1089	Ubiquitination	PNTDPWLLRSKSPVG CCCCCCHHCCCCCCC	5.26	23503661
1090	Phosphorylation	NTDPWLLRSKSPVGN CCCCCHHCCCCCCCC	39.61	32645325
1091	Phosphorylation	TDPWLLRSKSPVGNP CCCCHHCCCCCCCCH	37.14	22167270
1091	Ubiquitination	TDPWLLRSKSPVGNP CCCCHHCCCCCCCCH	37.14	23503661
1092	Phosphorylation	DPWLLRSKSPVGNPQ CCCHHCCCCCCCCHH	52.96	18669648
1092	Ubiquitination	DPWLLRSKSPVGNPQ CCCHHCCCCCCCCHH	52.96	23503661
1093	Phosphorylation	PWLLRSKSPVGNPQL CCHHCCCCCCCCHHH	26.51	22167270
1093	Ubiquitination	PWLLRSKSPVGNPQL CCHHCCCCCCCCHHH	26.51	23503661
1131	Ubiquitination	FIPSYHHHFAKQCRV CCCCCCHHHHHHCCC	15.85	29967540
1134	Ubiquitination	SYHHHFAKQCRVSDY CCCHHHHHHCCCCCC	49.33	29967540
1145	Acetylation	VSDYGYSKLIELLEA CCCCCHHHHHHHHHH	45.03	19815777
1185	Ubiquitination	RFTQDLLKLLKSQAS HHHHHHHHHHHHHHC	60.10	29967540
1188	Ubiquitination	QDLLKLLKSQASKQV HHHHHHHHHHHCCHH	51.46	29967540
1193	Ubiquitination	LLKSQASKQVIVREF HHHHHHCCHHHHHHH	52.15	-
1258	Ubiquitination	ERTQDEIERTKQFSK CCCHHHHHHHHHHCH	52.85	29967540
1259	Ubiquitination	RTQDEIERTKQFSKD CCHHHHHHHHHHCHH	53.54	25015289
1260	Ubiquitination	TQDEIERTKQFSKDV CHHHHHHHHHHCHHH	19.19	25015289
1261	Ubiquitination	QDEIERTKQFSKDVV HHHHHHHHHHCHHHH	56.41	29967540
1262	Ubiquitination	DEIERTKQFSKDVVD HHHHHHHHHCHHHHH	47.43	29967540
1265	Ubiquitination	ERTKQFSKDVVDLLR HHHHHHCHHHHHHHH	56.69	29967540
1295	Ubiquitination	YHHHFGRQCKLAYYG HHHHHHHHHHHHHCH	29.13	25015289
1296	Ubiquitination	HHHFGRQCKLAYYGF HHHHHHHHHHHHCHH	3.62	25015289
1331	Phosphorylation	EEKILTLTEVERFKA CCEEEEHHHHHHHHH	32.52	25159151
1334	Ubiquitination	ILTLTEVERFKALAA EEEHHHHHHHHHHHH	46.28	29967540
1337	Ubiquitination	LTEVERFKALAAQFV HHHHHHHHHHHHHHH	49.03	29967540
1342	Ubiquitination	RFKALAAQFVKLLRS HHHHHHHHHHHHHHC	37.75	29967540
1345	Ubiquitination	ALAAQFVKLLRSQKD HHHHHHHHHHHCCCC	42.99	29967540
1385	Ubiquitination	DVSSISALTQKLCHV CHHHHHHHHHHHCCE	4.10	25015289
1388	Ubiquitination	SISALTQKLCHVVKV HHHHHHHHHCCEEEH	48.09	29967540
1391	Ubiquitination	ALTQKLCHVVKVADI HHHHHHCCEEEHHHC	37.53	29967540
1394	Ubiquitination	QKLCHVVKVADIESG HHHCCEEEHHHCCCC	30.53	29967540
1411	Phosphorylation	IQLINRKSLRSLTAQ EEEECHHHHHHHHHH	26.27	-
1414	Phosphorylation	INRKSLRSLTAQLLV ECHHHHHHHHHHHHH	35.05	-
1425	Phosphorylation	QLLVLLMSWEGTTHL HHHHHHHCCCCCCCC	23.19	25348772
1429	Phosphorylation	LLMSWEGTTHLSVEE HHHCCCCCCCCCHHH	10.26	25348772
1429	Ubiquitination	LLMSWEGTTHLSVEE HHHCCCCCCCCCHHH	10.26	25015289
1430	Phosphorylation	LMSWEGTTHLSVEEL HHCCCCCCCCCHHHH	31.51	25348772
1433	Phosphorylation	WEGTTHLSVEELKRH CCCCCCCCHHHHHHH	21.63	25348772
1435	Ubiquitination	GTTHLSVEELKRHYE CCCCCCHHHHHHHHH	54.99	25015289
1437	Ubiquitination	THLSVEELKRHYEST CCCCHHHHHHHHHHC	3.60	25015289
1438	Ubiquitination	HLSVEELKRHYESTH CCCHHHHHHHHHHCC	40.17	25015289
1439	Ubiquitination	LSVEELKRHYESTHN CCHHHHHHHHHHCCC	50.69	25015289
1501	Phosphorylation	VRSLLHTYHYQQIFL HHHHHHHHHHHHHHH	6.43	18083107
1515	Phosphorylation	LHEFSMAYTKYVGET HHHHHHHHHHHCCCC	8.63	18083107
1518	Phosphorylation	FSMAYTKYVGETLQP HHHHHHHHCCCCCCC	13.09	18083107
1558	Ubiquitination	HKRIVVLKNDMKSRL CCEEEEEECHHHHHH	39.01	-
1559	Ubiquitination	KRIVVLKNDMKSRLS CEEEEEECHHHHHHH	50.91	29967540
1562	Ubiquitination	VVLKNDMKSRLSSLS EEEECHHHHHHHHCC	34.98	29967540
1563	Phosphorylation	VLKNDMKSRLSSLSL EEECHHHHHHHHCCC	31.64	28450419
1566	Phosphorylation	NDMKSRLSSLSLSPA CHHHHHHHHCCCCCC	28.29	30266825
1567	Phosphorylation	DMKSRLSSLSLSPAN HHHHHHHHCCCCCCC	26.94	30266825
1568	Phosphorylation	MKSRLSSLSLSPANH HHHHHHHCCCCCCCC	5.54	32142685
1569	Phosphorylation	KSRLSSLSLSPANHE HHHHHHCCCCCCCCC	28.84	30266825
1571	Phosphorylation	RLSSLSLSPANHENQ HHHHCCCCCCCCCCC	20.70	23401153
1580	Phosphorylation	ANHENQPSEGERILE CCCCCCCCCCCEEEE	48.77	23403867
1595	Ubiquitination	VPESHTASELKLGAD CCCCCCCCEECCCCC	44.62	29967540
1598	Ubiquitination	SHTASELKLGADGSG CCCCCEECCCCCCCC	40.60	29967540
1635	Phosphorylation	PVPSCLPSPQLRPDP CCCCCCCCCCCCCCC	16.60	26074081
1685	Phosphorylation	GKSKTLTSDSSSSCI CCCCCCCCCCCCCCE	38.31	30576142
1703	Phosphorylation	VPVPPCPSSETSESL CCCCCCCCCCCCHHH	47.74	30576142
1709	Phosphorylation	PSSETSESLLSKDPV CCCCCCHHHHCCCCC	34.08	24719451
1718	Phosphorylation	LSKDPVESPAKKQPK HCCCCCCCCCCCCCC	30.32	29255136

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MARF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MARF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MARF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NISCH_HUMAN	NISCH	physical	27173435
PCGF5_HUMAN	PCGF5	physical	27173435
PCGF3_HUMAN	PCGF3	physical	27173435
K1671_HUMAN	KIAA1671	physical	27173435
ARI3A_HUMAN	ARID3A	physical	27173435
RB_HUMAN	RB1	physical	27173435
P121A_HUMAN	POM121	physical	27173435
ARI3B_HUMAN	ARID3B	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1091, AND MASSSPECTROMETRY.
PubMed: 19690332

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-583 AND SER-915, ANDMASS SPECTROMETRY.
PubMed: 17081983