dbPTM

K1671_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	K1671_HUMAN
UniProt AC	Q9BY89
Protein Name	Uncharacterized protein KIAA1671
Gene Name	KIAA1671
Organism	Homo sapiens (Human).
Sequence Length	1806
Subcellular Localization
Protein Description
Protein Sequence	MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVTPEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGRDPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHLENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPADLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEEHCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQARTHPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDTFSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSPVEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEALEMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGPRPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLDIDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRPSLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSFCKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTEEKSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQSLYENQV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MATRVEVGSI -----CCCEEECCCC	47.29	20068231
3 (in isoform 2)	Phosphorylation	-	47.29	23663014
4 (in isoform 2)	Phosphorylation	-	29.65	23663014
5 (in isoform 2)	Phosphorylation	-	6.41	23663014
8 (in isoform 2)	Phosphorylation	-	10.38	23663014
9	Phosphorylation	ATRVEVGSITPLTAV CCEEECCCCCCCCCC	28.59	20068231
11	Phosphorylation	RVEVGSITPLTAVPG EEECCCCCCCCCCCC	17.59	28555341
14	Phosphorylation	VGSITPLTAVPGLGE CCCCCCCCCCCCCCC	27.15	27251275
27	Phosphorylation	GEMGKEETLTRTYFL CCCCCHHCEEEEEEH	34.22	19664995
29	Phosphorylation	MGKEETLTRTYFLQA CCCHHCEEEEEEHHH	28.52	19664995
52	Phosphorylation	ARILEAKSPLRSPAR HHHHCCCCCCCCCCH	35.89	25159151
56	Phosphorylation	EAKSPLRSPARLLPL CCCCCCCCCCHHCCC	30.51	25159151
79	Phosphorylation	SKEQDVKSPVPSLRP CCCCCCCCCCCCCCC	30.86	25159151
83	Phosphorylation	DVKSPVPSLRPSSTG CCCCCCCCCCCCCCC	36.93	21712546
87	Phosphorylation	PVPSLRPSSTGPSPS CCCCCCCCCCCCCCC	33.81	25159151
88	Phosphorylation	VPSLRPSSTGPSPSG CCCCCCCCCCCCCCC	39.81	25159151
89	Phosphorylation	PSLRPSSTGPSPSGG CCCCCCCCCCCCCCC	58.40	25159151
92	Phosphorylation	RPSSTGPSPSGGLSE CCCCCCCCCCCCCCC	32.80	25159151
94	Phosphorylation	SSTGPSPSGGLSEEP CCCCCCCCCCCCCCH	50.24	24732914
98	Phosphorylation	PSPSGGLSEEPAAKD CCCCCCCCCCHHHHC	43.09	21082442
104	Ubiquitination	LSEEPAAKDLDNRMP CCCCHHHHCCCCCCC	62.01	29967540
120	Phosphorylation	LVGQEVGSGEGPRTS CCCCCCCCCCCCCCC	38.56	22199227
126	Phosphorylation	GSGEGPRTSSPLFNK CCCCCCCCCCCCCCC	36.37	23403867
127	Phosphorylation	SGEGPRTSSPLFNKA CCCCCCCCCCCCCCE	31.10	25159151
128	Phosphorylation	GEGPRTSSPLFNKAV CCCCCCCCCCCCCEE	25.63	30266825
140	Phosphorylation	KAVFLRPSSSTMILF CEEEECCCCCEEEEE	30.41	27732954
141	Phosphorylation	AVFLRPSSSTMILFE EEEECCCCCEEEEEE	32.29	27732954
142	Phosphorylation	VFLRPSSSTMILFET EEECCCCCEEEEEEE	26.74	27732954
143	Phosphorylation	FLRPSSSTMILFETT EECCCCCEEEEEEEC	15.35	27732954
149	Phosphorylation	STMILFETTKSGPAL CEEEEEEECCCCHHH	31.99	27732954
150	Phosphorylation	TMILFETTKSGPALG EEEEEEECCCCHHHH	18.93	27732954
152	Phosphorylation	ILFETTKSGPALGKA EEEEECCCCHHHHHH	48.17	27251275
161	Phosphorylation	PALGKAVSEGAEEAK HHHHHHHHCCHHHHH	34.86	24719451
172	Phosphorylation	EEAKLGVSGSRPEVA HHHHCCCCCCCCHHH	29.29	25627689
174	Phosphorylation	AKLGVSGSRPEVAAK HHCCCCCCCCHHHCC	36.84	23312004
186	Phosphorylation	AAKPALPTQKPAGTL HCCCCCCCCCCCCCC	50.50	27732954
192	Phosphorylation	PTQKPAGTLPRSAPL CCCCCCCCCCCCCCC	35.38	23403867
222	Phosphorylation	DHPPSKASSVEDTAR CCCCCCCCCHHHCCC	38.36	27251275
223	Phosphorylation	HPPSKASSVEDTARP CCCCCCCCHHHCCCC	34.09	27251275
244	Phosphorylation	RLKRRPVSAIFTESI CCCCCCCEEEEECCC	20.52	29255136
245	Ubiquitination	LKRRPVSAIFTESIQ CCCCCCEEEEECCCC	10.93	21890473
245 (in isoform 2)	Ubiquitination	-	10.93	21890473
248	Phosphorylation	RPVSAIFTESIQPQK CCCEEEEECCCCCCC	23.78	29255136
250	Phosphorylation	VSAIFTESIQPQKPG CEEEEECCCCCCCCC	24.38	29255136
263	Phosphorylation	PGPGAAATVGKVPPT CCCCCCCCCCCCCCC	25.68	27080861
270	Phosphorylation	TVGKVPPTPPEKTWV CCCCCCCCCCCCCCC	45.46	21815630
284	Phosphorylation	VRKPRPLSMDLTARF CCCCCCCCCCCHHHH	16.97	30266825
288	Phosphorylation	RPLSMDLTARFENKE CCCCCCCHHHHCCHH	16.12	30266825
306	Phosphorylation	RKVADEGSGPTAGDM HHHHHCCCCCCHHHC	39.28	28555341
309	Phosphorylation	ADEGSGPTAGDMAGL HHCCCCCCHHHCCCC	46.96	23828894
323	Phosphorylation	LERPRAASKLDRDCL CCCHHHHHHCCHHHH	32.54	24719451
357	Acetylation	KIRERKEKMLSKPEM HHHHHHHHHHCCCCC	48.45	26051181
360	Phosphorylation	ERKEKMLSKPEMGSP HHHHHHHCCCCCCCC	42.54	24732914
361	Acetylation	RKEKMLSKPEMGSPR HHHHHHCCCCCCCCC	40.82	26051181
366	Phosphorylation	LSKPEMGSPRALVGG HCCCCCCCCCEECCC	15.20	25159151
375	Phosphorylation	RALVGGSSGVTPSND CEECCCCCCCCCCCC	40.32	20068231
378	Phosphorylation	VGGSSGVTPSNDQSP CCCCCCCCCCCCCCH	25.23	20068231
380	Phosphorylation	GSSGVTPSNDQSPWE CCCCCCCCCCCCHHH	43.61	20068231
384	Phosphorylation	VTPSNDQSPWEEKAK CCCCCCCCHHHHHCC	34.54	25159151
389	Ubiquitination	DQSPWEEKAKLDPEP CCCHHHHHCCCCCCH	39.03	29967540
402	Phosphorylation	EPEKAAESPSPRLGR CHHHHCCCCCCCCCC	26.42	29255136
404	Phosphorylation	EKAAESPSPRLGRGL HHHCCCCCCCCCCCH	31.75	29255136
409	Methylation	SPSPRLGRGLELAEV CCCCCCCCCHHHHHH	51.63	115481085
417	Ubiquitination	GLELAEVKSRVADGE CHHHHHHHHHHCCCC	24.85	29967540
442	Phosphorylation	RSVRKCISLFREDST HHHHHHHHHHCCCCE	30.81	29802988
448	Phosphorylation	ISLFREDSTLALAVG HHHHCCCCEEEEEEC	22.14	26657352
449	Phosphorylation	SLFREDSTLALAVGS HHHCCCCEEEEEECC	28.50	26657352
456	Phosphorylation	TLALAVGSESPLATP EEEEEECCCCCCCCC	28.44	22199227
458	Phosphorylation	ALAVGSESPLATPAS EEEECCCCCCCCCCC	27.23	22199227
462	Phosphorylation	GSESPLATPASPSAA CCCCCCCCCCCCCCC	27.37	22199227
465	Phosphorylation	SPLATPASPSAAPEP CCCCCCCCCCCCCCC	22.16	30278072
467	Phosphorylation	LATPASPSAAPEPEK CCCCCCCCCCCCCCC	34.27	22199227
490	Phosphorylation	IRGWTAESSEAKPEV HCCCCCCCCCCCHHH	30.89	27251275
501	Phosphorylation	KPEVRRRTFQARPLS CHHHHHHHHHCCCCC	20.49	23403867
508	Phosphorylation	TFQARPLSADLTKLF HHHCCCCCHHHHHHH	23.55	30266825
512	Phosphorylation	RPLSADLTKLFSSSA CCCCHHHHHHHHCCC	26.67	30266825
516	Phosphorylation	ADLTKLFSSSASSNE HHHHHHHHCCCCCCC	33.54	29802988
517	Phosphorylation	DLTKLFSSSASSNEV HHHHHHHCCCCCCCC	23.69	28348404
518	Phosphorylation	LTKLFSSSASSNEVK HHHHHHCCCCCCCCE	30.85	25159151
520	Phosphorylation	KLFSSSASSNEVKYE HHHHCCCCCCCCEEE	35.33	28348404
521	Phosphorylation	LFSSSASSNEVKYEK HHHCCCCCCCCEEEH	36.40	28348404
526	Phosphorylation	ASSNEVKYEKSAELS CCCCCCEEEHHHHHC	33.49	27642862
528	Ubiquitination	SNEVKYEKSAELSGE CCCCEEEHHHHHCCC	52.45	29967540
533	Phosphorylation	YEKSAELSGEFPKEP EEHHHHHCCCCCCCH	27.99	21815630
538	Ubiquitination	ELSGEFPKEPREKQK HHCCCCCCCHHHHCC	82.65	29967540
549	Phosphorylation	EKQKEGHSLDGACIP HHCCCCCCCCCCCCC	38.73	23927012
558	Phosphorylation	DGACIPRSPWKPGTL CCCCCCCCCCCCCCC	29.74	27422710
564	Phosphorylation	RSPWKPGTLRDKSRQ CCCCCCCCCCCCCCC	27.44	23927012
589	Phosphorylation	PDSCRGGSSVEAPCP CCCCCCCCCCCCCCC	33.75	22167270
590	Phosphorylation	DSCRGGSSVEAPCPS CCCCCCCCCCCCCCC	27.53	29496963
597	Phosphorylation	SVEAPCPSDVTPEDD CCCCCCCCCCCCCCC	51.97	30266825
600	Phosphorylation	APCPSDVTPEDDRSF CCCCCCCCCCCCCCH	26.42	30266825
628	Phosphorylation	RHTVADQSGRCLSTT HCEEECCCCCCCCCC	28.84	30631047
633	Phosphorylation	DQSGRCLSTTPPGDM CCCCCCCCCCCCCCC	33.58	23403867
634	Phosphorylation	QSGRCLSTTPPGDMA CCCCCCCCCCCCCCC	30.30	23927012
635	Phosphorylation	SGRCLSTTPPGDMAH CCCCCCCCCCCCCCC	24.90	23927012
646	Phosphorylation	DMAHARVSEPRPRPE CCCCCCCCCCCCCCC	36.01	25159151
656	Phosphorylation	RPRPEMGSWLGRDPP CCCCCCCCCCCCCCC	20.16	-
673	Phosphorylation	TKLKKENSRGFDNPE HHHHHHHCCCCCCHH	34.57	25159151
683	Ubiquitination	FDNPETEKLGPTTLL CCCHHHHCCCCCCEE	67.19	29967540
697	Phosphorylation	LNGELRPYHTPLRDK ECCCCCCCCCCCCCC	16.34	27642862
699	Phosphorylation	GELRPYHTPLRDKYP CCCCCCCCCCCCCCC	20.41	25159151
704	Ubiquitination	YHTPLRDKYPLSENH CCCCCCCCCCCCCCC	42.19	29967540
725	Phosphorylation	KHLENPPTSQRIEPR HHCCCCCCCCCCCCC	38.46	25627689
726	Phosphorylation	HLENPPTSQRIEPRY HCCCCCCCCCCCCCC	24.20	25627689
733	Phosphorylation	SQRIEPRYDIVHAVG CCCCCCCCHHHHHCC	22.27	25394399
745	Phosphorylation	AVGERVHSEAISPAP HCCCHHHHCCCCCCC	26.35	23403867
749	Phosphorylation	RVHSEAISPAPEEKA HHHHCCCCCCCHHHH	23.27	29255136
755	Ubiquitination	ISPAPEEKAVTLRSL CCCCCHHHHHHHHHH	46.63	29967540
758	Phosphorylation	APEEKAVTLRSLRSW CCHHHHHHHHHHHHH	22.70	22210691
761	Phosphorylation	EKAVTLRSLRSWLSL HHHHHHHHHHHHHCC	31.11	22210691
764	Phosphorylation	VTLRSLRSWLSLKDR HHHHHHHHHHCCCHH	37.35	20860994
767	Phosphorylation	RSLRSWLSLKDRQLS HHHHHHHCCCHHHHC	27.41	24501219
774	Phosphorylation	SLKDRQLSQEVTPAD CCCHHHHCCCCCHHH	18.89	25159151
778	Phosphorylation	RQLSQEVTPADLECG HHHCCCCCHHHHHCC	16.41	25394399
792	Phosphorylation	GLEGQAGSVQRASLI CCCCCCCCCCHHHHH	20.35	20068231
797	Phosphorylation	AGSVQRASLIWEARG CCCCCHHHHHHHHCC	23.68	28857561
812	Ubiquitination	MPEASGPKFGGNCPF CCCCCCCCCCCCCCC	61.23	29967540
821	Acetylation	GGNCPFPKWTGGAVV CCCCCCCCCCCCEEE	58.74	26051181
823	Phosphorylation	NCPFPKWTGGAVVSS CCCCCCCCCCEEEEC	31.68	21955146
829	Phosphorylation	WTGGAVVSSHKATVA CCCCEEEECCEEEEE	21.81	21955146
830	Phosphorylation	TGGAVVSSHKATVAV CCCEEEECCEEEEEE	19.87	21955146
834	Phosphorylation	VVSSHKATVAVSEEH EEECCEEEEEECHHH	17.50	21955146
838	Phosphorylation	HKATVAVSEEHCAPG CEEEEEECHHHCCCC	27.77	21955146
842	S-nitrosylation	VAVSEEHCAPGATSV EEECHHHCCCCCCHH	5.74	22178444
847	Phosphorylation	EHCAPGATSVRAIKA HHCCCCCCHHHHHHH	33.40	21955146
848	Phosphorylation	HCAPGATSVRAIKAA HCCCCCCHHHHHHHH	14.74	21955146
853	Methylation	ATSVRAIKAAIWESQ CCHHHHHHHHHHHCC	30.68	115972039
853	Ubiquitination	ATSVRAIKAAIWESQ CCHHHHHHHHHHHCC	30.68	29967540
859	Phosphorylation	IKAAIWESQHEGPEG HHHHHHHCCCCCCCC	23.11	28348404
951	Phosphorylation	MDRWRRRTLPPNVKF HHHHHHCCCCCCCCC	41.63	27273156
960	Phosphorylation	PPNVKFDTFSSLVPE CCCCCCCCHHHCCCC	28.66	23312004
962	Phosphorylation	NVKFDTFSSLVPEDS CCCCCCHHHCCCCCC	25.51	23312004
963	Phosphorylation	VKFDTFSSLVPEDSP CCCCCHHHCCCCCCC	29.24	21712546
969	Phosphorylation	SSLVPEDSPHVGHRR HHCCCCCCCCCCCCC	18.42	25159151
977	Phosphorylation	PHVGHRRTDYVSPTA CCCCCCCCCCCCCCH	31.47	28152594
979	Phosphorylation	VGHRRTDYVSPTASA CCCCCCCCCCCCHHH	11.38	28152594
981	Phosphorylation	HRRTDYVSPTASALR CCCCCCCCCCHHHHH	15.42	25159151
983	Phosphorylation	RTDYVSPTASALRKP CCCCCCCCHHHHHCC	26.24	28152594
985	Phosphorylation	DYVSPTASALRKPQL CCCCCCHHHHHCCCC	30.25	25159151
989	Ubiquitination	PTASALRKPQLSHYR CCHHHHHCCCCCCEE	37.66	29967540
999	Phosphorylation	LSHYRVETQEVNPGA CCCEEEEEEECCCCC	27.46	23312004
1007	Phosphorylation	QEVNPGASRDQTSPA EECCCCCCCCCCCCC	42.16	25159151
1011	Phosphorylation	PGASRDQTSPAVKQG CCCCCCCCCCCHHCC	40.75	26657352
1012	Phosphorylation	GASRDQTSPAVKQGS CCCCCCCCCCHHCCC	12.77	25159151
1019	Phosphorylation	SPAVKQGSPVEPKAT CCCHHCCCCCCCCCE	24.23	25159151
1026	Phosphorylation	SPVEPKATFFAVTYQ CCCCCCCEEEEEEEE	25.97	21945579
1031	Phosphorylation	KATFFAVTYQIPNTQ CCEEEEEEEECCCCC	13.28	21945579
1032	Phosphorylation	ATFFAVTYQIPNTQK CEEEEEEEECCCCCC	9.61	21945579
1037	Phosphorylation	VTYQIPNTQKAKGVV EEEECCCCCCCCEEE	26.54	21945579
1050	Phosphorylation	VVLSGAESLLEHSRK EEEECHHHHHHHHHC	37.41	28857561
1055	Phosphorylation	AESLLEHSRKITPPS HHHHHHHHHCCCCCC	26.37	28555341
1059	Phosphorylation	LEHSRKITPPSSPHS HHHHHCCCCCCCCCC	31.98	25159151
1062	Phosphorylation	SRKITPPSSPHSLTS HHCCCCCCCCCCHHH	58.67	25159151
1063	Phosphorylation	RKITPPSSPHSLTST HCCCCCCCCCCHHHH	32.19	25159151
1066	Phosphorylation	TPPSSPHSLTSTLVS CCCCCCCCHHHHHHH	36.40	21712546
1068	Phosphorylation	PSSPHSLTSTLVSLG CCCCCCHHHHHHHCC	23.76	21712546
1069	Phosphorylation	SSPHSLTSTLVSLGH CCCCCHHHHHHHCCH	25.66	23403867
1070	Phosphorylation	SPHSLTSTLVSLGHE CCCCHHHHHHHCCHH	26.41	26657352
1073	Phosphorylation	SLTSTLVSLGHEEAL CHHHHHHHCCHHHHH	31.57	23403867
1085	Phosphorylation	EALEMAGSKNWMKGR HHHHHHCCCCCCCCC	17.18	23403867
1098	Phosphorylation	GREHENASILKTLKP CCCCCCCCHHHHCCC	39.78	24719451
1102	Phosphorylation	ENASILKTLKPTDRP CCCCHHHHCCCCCCC	36.25	28348404
1106	Phosphorylation	ILKTLKPTDRPSSLG HHHHCCCCCCCCCCC	42.95	28348404
1110	Phosphorylation	LKPTDRPSSLGAWSL CCCCCCCCCCCCEEE	38.80	25159151
1111	Phosphorylation	KPTDRPSSLGAWSLD CCCCCCCCCCCEEEC	33.24	25106551
1132	Phosphorylation	IDVDALWSHRGSEDG EEHHHHHHCCCCCCC	12.26	24719451
1136	Phosphorylation	ALWSHRGSEDGPRPQ HHHHCCCCCCCCCCC	32.25	27174698
1144	Phosphorylation	EDGPRPQSNWKESAN CCCCCCCCCHHHHHH	47.55	27174698
1149	Phosphorylation	PQSNWKESANKMSPS CCCCHHHHHHCCCCC	33.15	24732914
1154	Phosphorylation	KESANKMSPSGGAPQ HHHHHCCCCCCCCCC	19.95	25159151
1156	Phosphorylation	SANKMSPSGGAPQTT HHHCCCCCCCCCCCC	42.42	23927012
1162	Phosphorylation	PSGGAPQTTPTLRSR CCCCCCCCCCCHHCC	33.41	25159151
1163	Phosphorylation	SGGAPQTTPTLRSRP CCCCCCCCCCHHCCC	14.72	25159151
1165	Phosphorylation	GAPQTTPTLRSRPKD CCCCCCCCHHCCCCC	32.48	24732914
1179	Phosphorylation	DLPVRRKTDVISDTF CCCCCCCCCCCCCCC	33.42	27273156
1183	Phosphorylation	RRKTDVISDTFPGKI CCCCCCCCCCCCCCC	30.37	30266825
1185	Phosphorylation	KTDVISDTFPGKIRD CCCCCCCCCCCCCCC	25.57	30266825
1196	Phosphorylation	KIRDGYRSSVLDIDA CCCCCCHHCCCCHHH	19.13	28348404
1197	Phosphorylation	IRDGYRSSVLDIDAL CCCCCHHCCCCHHHH	20.08	28348404
1208	Phosphorylation	IDALMAEYQELSLKV HHHHHHHHHHHHCCC	9.57	27642862
1212	Phosphorylation	MAEYQELSLKVPGEA HHHHHHHHCCCCCCH	25.95	27174698
1224	Phosphorylation	GEAQERRSPTVEPST CCHHHCCCCCCCCCC	31.01	29255136
1226	Phosphorylation	AQERRSPTVEPSTLP HHHCCCCCCCCCCCC	38.45	29255136
1230	Phosphorylation	RSPTVEPSTLPRERP CCCCCCCCCCCCCCC	29.13	23927012
1231	Phosphorylation	SPTVEPSTLPRERPV CCCCCCCCCCCCCCC	52.04	23927012
1249	Phosphorylation	GVEQRRRSLKEMPDT CHHHHHHHHHCCCCC	41.82	24719451
1264	Phosphorylation	GGLWKPASSAEINHS CCCCCCCCCCCCCCC	38.31	25159151
1265	Phosphorylation	GLWKPASSAEINHSF CCCCCCCCCCCCCCC	31.84	28348404
1271	Phosphorylation	SSAEINHSFTPGLGK CCCCCCCCCCCCHHH	26.74	25159151
1273	Phosphorylation	AEINHSFTPGLGKQL CCCCCCCCCCHHHHH	21.33	25159151
1283	Phosphorylation	LGKQLAETLETAMGT HHHHHHHHHHHHHCC	25.04	25599653
1292	Phosphorylation	ETAMGTKSSPPFWAL HHHHCCCCCCCCCCC	48.17	30266825
1293	Phosphorylation	TAMGTKSSPPFWALP HHHCCCCCCCCCCCC	37.84	30266825
1308	Phosphorylation	PSAPSERYPGGSPIP CCCCCCCCCCCCCCC	11.37	21712546
1312	Phosphorylation	SERYPGGSPIPADPR CCCCCCCCCCCCCCC	26.10	25159151
1358	Phosphorylation	SGREDPGSGVRVSPK CCCCCCCCCCCCCCC	39.23	23312004
1363	Phosphorylation	PGSGVRVSPKSPPTD CCCCCCCCCCCCCCC	18.95	30266825
1366	Phosphorylation	GVRVSPKSPPTDQKK CCCCCCCCCCCCCCC	39.22	25159151
1369	Phosphorylation	VSPKSPPTDQKKGTP CCCCCCCCCCCCCCC	55.22	30266825
1379	Phosphorylation	KKGTPRKSTGRGEED CCCCCCCCCCCCCCC	37.06	28985074
1380	Phosphorylation	KGTPRKSTGRGEEDS CCCCCCCCCCCCCCC	33.65	25106551
1382	Methylation	TPRKSTGRGEEDSVA CCCCCCCCCCCCCHH	49.81	115481089
1387	Phosphorylation	TGRGEEDSVAQWGDH CCCCCCCCHHHCCCC	23.72	25159151
1409	Phosphorylation	PLDIKRAYSEKGPPA CCCHHHHHHCCCCCC	22.77	23312004
1410	Phosphorylation	LDIKRAYSEKGPPAN CCHHHHHHCCCCCCC	31.67	26657352
1441	Phosphorylation	EQPKGRPSLTGENLE HCCCCCCCCCCCCCC	36.88	25159151
1443	Phosphorylation	PKGRPSLTGENLEAK CCCCCCCCCCCCCCC	46.95	25849741
1465	Ubiquitination	SGTGDSHKVLPRDLE CCCCCCCCCCCHHHC	49.79	-
1488	Phosphorylation	ERPLQQVSPVASVPW CCCHHHCCCCCCCCC	14.87	22167270
1492	Phosphorylation	QQVSPVASVPWRSHS HHCCCCCCCCCCCCC	29.01	23403867
1497	Phosphorylation	VASVPWRSHSFCKDR CCCCCCCCCCCCCCC	21.44	24719451
1499	Phosphorylation	SVPWRSHSFCKDRRS CCCCCCCCCCCCCCC	33.32	30576142
1506	Phosphorylation	SFCKDRRSGPFVDQL CCCCCCCCCCHHHHH	52.27	30266825
1522	Phosphorylation	QCFSRQPTEPKDTDT HHHHCCCCCCCCCCC	57.49	-
1527	Phosphorylation	QPTEPKDTDTLVHEA CCCCCCCCCCCEECC	36.69	29978859
1529	Phosphorylation	TEPKDTDTLVHEAGS CCCCCCCCCEECCCC	32.54	29978859
1536	Phosphorylation	TLVHEAGSQYGTWTE CCEECCCCCCCCCCC	27.55	29978859
1538	Phosphorylation	VHEAGSQYGTWTEQC EECCCCCCCCCCCCC	20.44	29978859
1540	Phosphorylation	EAGSQYGTWTEQCQS CCCCCCCCCCCCCCC	25.03	29978859
1542	Phosphorylation	GSQYGTWTEQCQSGE CCCCCCCCCCCCCCC	18.93	29978859
1547	Phosphorylation	TWTEQCQSGESLATE CCCCCCCCCCCCCCC	52.75	29978859
1550	Phosphorylation	EQCQSGESLATESPD CCCCCCCCCCCCCCC	27.16	29978859
1553	Phosphorylation	QSGESLATESPDSSA CCCCCCCCCCCCCCC	42.14	28348404
1555	Phosphorylation	GESLATESPDSSATS CCCCCCCCCCCCCCC	29.65	29978859
1569	Phosphorylation	STRKQPPSSRLSSLS CCCCCCCCHHHHHCC	34.47	24719451
1573	Phosphorylation	QPPSSRLSSLSSQTE CCCCHHHHHCCCCCC	28.29	25159151
1574	Phosphorylation	PPSSRLSSLSSQTEP CCCHHHHHCCCCCCC	36.54	25159151
1576	Phosphorylation	SSRLSSLSSQTEPTS CHHHHHCCCCCCCCC	23.50	25106551
1577	Phosphorylation	SRLSSLSSQTEPTSA HHHHHCCCCCCCCCC	46.55	30108239
1579	Phosphorylation	LSSLSSQTEPTSAGD HHHCCCCCCCCCCCC	45.97	30108239
1582	Phosphorylation	LSSQTEPTSAGDQYD CCCCCCCCCCCCCCC	25.61	23090842
1583	Phosphorylation	SSQTEPTSAGDQYDC CCCCCCCCCCCCCCC	40.75	30108239
1588	Phosphorylation	PTSAGDQYDCSRDQR CCCCCCCCCCCCCCC	24.53	27642862
1596	Phosphorylation	DCSRDQRSTSVDHSS CCCCCCCCCCCCCCC	21.28	23927012
1597	Phosphorylation	CSRDQRSTSVDHSST CCCCCCCCCCCCCCC	34.65	23663014
1598	Phosphorylation	SRDQRSTSVDHSSTD CCCCCCCCCCCCCCC	27.13	23663014
1602	Phosphorylation	RSTSVDHSSTDLEST CCCCCCCCCCCCCCC	30.39	23663014
1603	Phosphorylation	STSVDHSSTDLESTD CCCCCCCCCCCCCCC	23.63	23663014
1604	Phosphorylation	TSVDHSSTDLESTDG CCCCCCCCCCCCCCC	47.84	23663014
1608	Phosphorylation	HSSTDLESTDGMEGP CCCCCCCCCCCCCCC	38.81	23663014
1609	Phosphorylation	SSTDLESTDGMEGPP CCCCCCCCCCCCCCC	27.48	23663014
1630	Phosphorylation	EKRVDDFSFIDQTSV CCCCCCCCCCCCCCC	28.43	-
1650	Phosphorylation	LKTRVQLSKRSRRRA HHHHHHHCHHHHHHC	14.66	24719451
1653	Phosphorylation	RVQLSKRSRRRAPIS HHHHCHHHHHHCCCC	33.60	28258704
1660	Phosphorylation	SRRRAPISHSLRRSR HHHHCCCCHHHHHHC	13.13	30266825
1662	Phosphorylation	RRAPISHSLRRSRFS HHCCCCHHHHHHCCC	19.44	30266825
1666	Phosphorylation	ISHSLRRSRFSESES CCHHHHHHCCCCCCC	31.10	30108239
1669	Phosphorylation	SLRRSRFSESESRSP HHHHHCCCCCCCCCC	38.82	23911959
1671	Phosphorylation	RRSRFSESESRSPLE HHHCCCCCCCCCCCC	39.41	30108239
1673	Phosphorylation	SRFSESESRSPLEDE HCCCCCCCCCCCCCC	47.54	30108239
1675	Phosphorylation	FSESESRSPLEDETD CCCCCCCCCCCCCCC	43.02	28348404
1681	Phosphorylation	RSPLEDETDNTWMFK CCCCCCCCCCCCCCC	47.04	23090842
1684	Phosphorylation	LEDETDNTWMFKDST CCCCCCCCCCCCCCC	22.55	23090842
1690	Phosphorylation	NTWMFKDSTEEKSPR CCCCCCCCCCCCCCC	38.01	29449344
1691	Phosphorylation	TWMFKDSTEEKSPRK CCCCCCCCCCCCCCC	59.29	29449344
1695	Phosphorylation	KDSTEEKSPRKEESD CCCCCCCCCCCCCCC	32.96	30576142
1701	Phosphorylation	KSPRKEESDEEETAS CCCCCCCCCHHHHHH	51.95	23401153
1706	Phosphorylation	EESDEEETASKAERT CCCCHHHHHHHHHCC	39.24	30576142
1708	Phosphorylation	SDEEETASKAERTPV CCHHHHHHHHHCCCC	39.56	23927012
1713	Phosphorylation	TASKAERTPVSHPQR HHHHHHCCCCCCCCC	21.39	25159151
1716	Phosphorylation	KAERTPVSHPQRMPA HHHCCCCCCCCCCCC	30.56	27251275
1733	Ubiquitination	GMDPAVLKAQLHKRP CCCHHHHHHHHCCCC	27.73	22817900
1738	Ubiquitination	VLKAQLHKRPEVDSP HHHHHHCCCCCCCCC	77.55	22817900
1738 (in isoform 1)	Ubiquitination	-	77.55	21890473
1744	Phosphorylation	HKRPEVDSPGETPSW CCCCCCCCCCCCCCC	39.72	30266825
1748	Phosphorylation	EVDSPGETPSWAPQP CCCCCCCCCCCCCCC	28.65	30266825
1750	Phosphorylation	DSPGETPSWAPQPKS CCCCCCCCCCCCCCC	43.20	30266825
1757	Phosphorylation	SWAPQPKSPKSPFQP CCCCCCCCCCCCCCC	44.22	28355574
1760	Phosphorylation	PQPKSPKSPFQPGVL CCCCCCCCCCCCCCC	34.04	30266825
1769	Phosphorylation	FQPGVLGSRVLPSSM CCCCCCCCCCCCCCC	18.30	20068231
1774	Phosphorylation	LGSRVLPSSMDKDER CCCCCCCCCCCCCCC	33.85	23403867
1775	Phosphorylation	GSRVLPSSMDKDERS CCCCCCCCCCCCCCC	29.12	23403867
1782	Phosphorylation	SMDKDERSDEPSPQW CCCCCCCCCCCCHHH	44.25	30266825
1786	Phosphorylation	DERSDEPSPQWLKEL CCCCCCCCHHHHHHH	27.89	30266825
1800	Phosphorylation	LKSKKRQSLYENQV- HHHHHHHHHHHCCC-	36.63	19664994
1802	Phosphorylation	SKKRQSLYENQV--- HHHHHHHHHCCC---	20.34	23403867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of K1671_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of K1671_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of K1671_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of K1671_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of K1671_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-128 AND THR-600, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"Large-scale phosphoproteome analysis of human liver tissue byenrichment and fractionation of phosphopeptides with strong anionexchange chromatography."; Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D.,Zou H., Gu J.; Proteomics 8:1346-1361(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1701, AND MASSSPECTROMETRY.	18318008 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-52; SER-56; SER-79;SER-83; SER-87; SER-88; THR-89; SER-92; SER-98; SER-128; SER-384;SER-508; SER-749; THR-1059; SER-1063; SER-1224; SER-1366; SER-1441;SER-1488; SER-1506; SER-1757; SER-1760 AND SER-1786, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-402; SER-465 ANDSER-1019, AND MASS SPECTROMETRY.	19007248 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-985, AND MASSSPECTROMETRY.	17924679 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1059 AND SER-1062, ANDMASS SPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1574, AND MASSSPECTROMETRY.	15302935 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-248, AND MASSSPECTROMETRY.	18187866 [Abstract]