dbPTM

PO5F1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PO5F1_MOUSE
UniProt AC	P20263
Protein Name	POU domain, class 5, transcription factor 1
Gene Name	Pou5f1
Organism	Mus musculus (Mouse).
Sequence Length	352
Subcellular Localization	Cytoplasm . Nucleus . Expressed in a diffuse and slightly punctuate pattern (By similarity). Colocalizes with MAPK8 and MAPK9 in the nucleus (PubMed:29153991).
Protein Description	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). [PubMed: 1972777]
Protein Sequence	MAGHLASDFAFSPPPGGGDGSAGLEPGWVDPRTWLSFQGPPGGPGIGPGSEVLGISPCPPAYEFCGGMAYCGPQVGLGLVPQVGVETLQPEGQAGARVESNSEGTSSEPCADRPNAVKLEKVEPTPEESQDMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSLKNMCKLRPLLEKWVEEADNNENLQEICKSETLVQARKRKRTSIENRVRWSLETMFLKCPKPSLQQITHIANQLGLEKDVVRVWFCNRRQKGKRSSIEYSQREEYEATGTPFPGGAVSFPLPPGPHFGTPGYGSPHFTTLYSVPFPEGEAFPSVPVTALGSPMHSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LASDFAFSPPPGGGD CCCCCCCCCCCCCCC	32.82	22006019
106	Phosphorylation	ESNSEGTSSEPCADR ECCCCCCCCCCCCCC	43.49	-
118	Sumoylation	ADRPNAVKLEKVEPT CCCCCCEEEEECCCC	48.82	-
118	Ubiquitination	ADRPNAVKLEKVEPT CCCCCCEEEEECCCC	48.82	-
118	Sumoylation	ADRPNAVKLEKVEPT CCCCCCEEEEECCCC	48.82	17525163
137	Ubiquitination	QDMKALQKELEQFAK HHHHHHHHHHHHHHH	66.18	-
144	Ubiquitination	KELEQFAKLLKQKRI HHHHHHHHHHHHCCC	56.49	-
199	Ubiquitination	KLRPLLEKWVEEADN HHHHHHHHHHHHHCC	57.41	-
215	Ubiquitination	ENLQEICKSETLVQA CCHHHHHHHHHHHHH	57.92	-
228	Phosphorylation	QARKRKRTSIENRVR HHHHHHCCCHHHHHH	36.77	-
228	O-linked_Glycosylation	QARKRKRTSIENRVR HHHHHHCCCHHHHHH	36.77	22608532
229	Phosphorylation	ARKRKRTSIENRVRW HHHHHCCCHHHHHHH	31.75	-
229	O-linked_Glycosylation	ARKRKRTSIENRVRW HHHHHCCCHHHHHHH	31.75	22608532
282	Phosphorylation	RQKGKRSSIEYSQRE CCCCCCCCCCHHHHH	24.38	-
343	Phosphorylation	AFPSVPVTALGSPMH CCCCCCEEECCCCCC	15.30	-
347	Phosphorylation	VPVTALGSPMHSN-- CCEEECCCCCCCC--	21.65	29153991

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
106	S	Phosphorylation	Kinase	MAPK	-	Uniprot
347	S	Phosphorylation	Kinase	MAPK8	P45983	GPS
347	S	Phosphorylation	Kinase	MAPK8	Q91Y86	Uniprot
347	S	Phosphorylation	Kinase	MAPK9	P45984	GPS
347	S	Phosphorylation	Kinase	MAPK9	Q9WTU6	Uniprot
-	K	Ubiquitination	E3 ubiquitin ligase	Wwp2	Q9DBH0	PMID:22199232

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
106	S	Phosphorylation	29153991
ERK1/2-mediated phosphorylation at Ser-106 promotes nuclear exclusion and proteasomal degradation.
228	T	Phosphorylation	29153991
Phosphorylation at Thr-228 and Ser-229 decrease DNA-binding and alters ability to activate transcription (By similarity).
229	S	Phosphorylation	29153991
Phosphorylation at Thr-228 and Ser-229 decrease DNA-binding and alters ability to activate transcription (By similarity).
347	S	Phosphorylation	29153991
JNK1/2-mediated phosphorylation at Ser-347 promotes proteasomal degradation.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PO5F1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERR2_MOUSE	Esrrb	physical	18662995
MBD3_MOUSE	Mbd3	physical	20362541
MTA2_MOUSE	Mta2	physical	20362541
MTA1_MOUSE	Mta1	physical	20362541
CHD4_MOUSE	Chd4	physical	20362541
SALL4_MOUSE	Sall4	physical	20362541
KDM1A_MOUSE	Kdm1a	physical	20362541
P66A_MOUSE	Gatad2a	physical	20362541
P66B_MOUSE	Gatad2b	physical	20362541
HDAC1_MOUSE	Hdac1	physical	20362541
MTA3_MOUSE	Mta3	physical	20362541
HDAC2_MOUSE	Hdac2	physical	20362541
RBBP7_MOUSE	Rbbp7	physical	20362541
SMRC1_MOUSE	Smarcc1	physical	20362541
SMCA4_MOUSE	Smarca4	physical	20362541
PHC1_MOUSE	Phc1	physical	20362541
RING2_MOUSE	Rnf2	physical	20362541
RYBP_MOUSE	Rybp	physical	20362541
EP400_MOUSE	Ep400	physical	20362541
ZMYM2_MOUSE	Zmym2	physical	20362541
RCOR2_MOUSE	Rcor2	physical	20362541
ARI3B_MOUSE	Arid3b	physical	20362541
WDR5_MOUSE	Wdr5	physical	20362541
SOX2_MOUSE	Sox2	physical	20362541
MGAP_MOUSE	Mga	physical	20362541
UBIP1_MOUSE	Ubp1	physical	20362541
NACC1_MOUSE	Nacc1	physical	20362541
HCFC1_MOUSE	Hcfc1	physical	20362541
HELLS_MOUSE	Hells	physical	20362541
SUH_MOUSE	Rbpj	physical	20362541
TF2L1_MOUSE	Tfcp2l1	physical	20362541
REQU_MOUSE	Dpf2	physical	20362541
ERR2_MOUSE	Esrrb	physical	20362541
PML_MOUSE	Pml	physical	20362541
FOXP4_MOUSE	Foxp4	physical	20362541
CTBP2_MOUSE	Ctbp2	physical	20362541
NR0B1_MOUSE	Nr0b1	physical	20362541
ZN143_MOUSE	Zfp143	physical	20362541
KLF5_MOUSE	Klf5	physical	20362541
RIF1_MOUSE	Rif1	physical	20362541
LITD1_MOUSE	L1td1	physical	20362541
AKAP8_MOUSE	Akap8	physical	20362541
MSH2_MOUSE	Msh2	physical	20362541
OGT1_MOUSE	Ogt	physical	20362541
RBM14_MOUSE	Rbm14	physical	20362541
FRG1_MOUSE	Frg1	physical	20362541
SMC1A_MOUSE	Smc1a	physical	20362541
EMSY_MOUSE	2210018M11Rik	physical	20362541
BAP18_MOUSE	0610010K14Rik	physical	20362541
K1551_MOUSE	2810474O19Rik	physical	20362541
ZCHC8_MOUSE	Zcchc8	physical	20362541
RYBP_MOUSE	Rybp	physical	17093407
EWS_MOUSE	Ewsr1	physical	17093407
ARI3B_MOUSE	Arid3b	physical	17093407
ILF2_MOUSE	Ilf2	physical	17093407
HDAC2_MOUSE	Hdac2	physical	17093407
P66B_MOUSE	Gatad2b	physical	17093407
SP1_MOUSE	Sp1	physical	17093407
CDK1_MOUSE	Cdk1	physical	17093407
REQU_MOUSE	Dpf2	physical	17093407
NANOG_MOUSE	Nanog	physical	17093407
ACINU_MOUSE	Acin1	physical	20362542
ACL6A_MOUSE	Actl6a	physical	20362542
AMOL2_MOUSE	Amotl2	physical	20362542
KDM1A_MOUSE	Kdm1a	physical	20362542
ARI3B_MOUSE	Arid3b	physical	20362542
ASF1A_MOUSE	Asf1a	physical	20362542
ATF2_MOUSE	Atf2	physical	20362542
BRWD1_MOUSE	Brwd1	physical	20362542
PYR1_MOUSE	Cad	physical	20362542
CHD1_MOUSE	Chd1	physical	20362542
CHD4_MOUSE	Chd4	physical	20362542
CHD5_MOUSE	Chd5	physical	20362542
CREB1_MOUSE	Creb1	physical	20362542
CTBP1_MOUSE	Ctbp1	physical	20362542
CTBP2_MOUSE	Ctbp2	physical	20362542
CUBN_MOUSE	Cubn	physical	20362542
CUL4B_MOUSE	Cul4b	physical	20362542
DDB1_MOUSE	Ddb1	physical	20362542
DHX9_MOUSE	Dhx9	physical	20362542
DNJA1_MOUSE	Dnaja1	physical	20362542
DNM3A_MOUSE	Dnmt3a	physical	20362542
DNM3L_MOUSE	Dnmt3l	physical	20362542
EMD_MOUSE	Emd	physical	20362542
P66A_MOUSE	Gatad2a	physical	20362542
P66B_MOUSE	Gatad2b	physical	20362542
HCFC1_MOUSE	Hcfc1	physical	20362542
HDAC1_MOUSE	Hdac1	physical	20362542
HELLS_MOUSE	Hells	physical	20362542
HIRA_MOUSE	Hira	physical	20362542
H2B3B_MOUSE	Hist3h2bb-ps	physical	20362542
ROAA_MOUSE	Hnrnpab	physical	20362542
HNRPL_MOUSE	Hnrnpl	physical	20362542
HNRPU_MOUSE	Hnrnpu	physical	20362542
IFI2_MOUSE	Ifi202b	physical	20362542
INO80_MOUSE	Ino80	physical	20362542
KLF4_MOUSE	Klf4	physical	20362542
IMA1_MOUSE	Kpna2	physical	20362542
IMA4_MOUSE	Kpna3	physical	20362542
MATR3_MOUSE	Matr3	physical	20362542
MBD3_MOUSE	Mbd3	physical	20362542
MITF_MOUSE	Mitf	physical	20362542
MSH6_MOUSE	Msh6	physical	20362542
MTA1_MOUSE	Mta1	physical	20362542
MTA2_MOUSE	Mta2	physical	20362542
MTA3_MOUSE	Mta3	physical	20362542
KAT7_MOUSE	Kat7	physical	20362542
NFRKB_MOUSE	Nfrkb	physical	20362542
NFYC_MOUSE	Nfyc	physical	20362542
NUDC_MOUSE	Nudc	physical	20362542
OGT1_MOUSE	Ogt	physical	20362542
P4HA1_MOUSE	P4ha1	physical	20362542
JADE1_MOUSE	Jade1	physical	20362542
PO5F1_MOUSE	Pou5f1	physical	20362542
2AAA_MOUSE	Ppp2r1a	physical	20362542
PSB6_MOUSE	Psmb6	physical	20362542
RCOR2_MOUSE	Rcor2	physical	20362542
RFX2_MOUSE	Rfx2	physical	20362542
RFA1_MOUSE	Rpa1	physical	20362542
RFA3_MOUSE	Rpa3	physical	20362542
SALL3_MOUSE	Sall3	physical	20362542
SALL4_MOUSE	Sall4	physical	20362542
SMCA4_MOUSE	Smarca4	physical	20362542
SMCA5_MOUSE	Smarca5	physical	20362542
SMRC1_MOUSE	Smarcc1	physical	20362542
SP1_MOUSE	Sp1	physical	20362542
SSRP1_MOUSE	Ssrp1	physical	20362542
SP16H_MOUSE	Supt16	physical	20362542
TFE3_MOUSE	Tfe3	physical	20362542
TFEB_MOUSE	Tfeb	physical	20362542
TOP2A_MOUSE	Top2a	physical	20362542
TIF1A_MOUSE	Trim24	physical	20362542
TRI33_MOUSE	Trim33	physical	20362542
TTF2_MOUSE	Ttf2	physical	20362542
UBN2_MOUSE	Ubn2	physical	20362542
XRCC1_MOUSE	Xrcc1	physical	20362542
XRCC5_MOUSE	Xrcc5	physical	20362542
XRCC6_MOUSE	Xrcc6	physical	20362542
ZBT43_MOUSE	Zbtb43	physical	20362542
ZN513_MOUSE	Zfp513	physical	20362542
NANOG_MOUSE	Nanog	physical	18454139
HDAC2_MOUSE	Hdac2	physical	18454139
PO5F1_MOUSE	Pou5f1	physical	18454139
MTA1_MOUSE	Mta1	physical	18454139
MTA2_MOUSE	Mta2	physical	18454139
MBD3_MOUSE	Mbd3	physical	18454139
RBBP7_MOUSE	Rbbp7	physical	18454139
SOX2_MOUSE	Sox2	physical	15863505
SOX15_MOUSE	Sox15	physical	15863505
ZN143_MOUSE	Zfp143	physical	18687992
NUCL_MOUSE	Ncl	physical	21048921
PO5F1_MOUSE	Pou5f1	physical	22083510
ACL6A_MOUSE	Actl6a	physical	22083510
ARP3_MOUSE	Actr3	physical	22083510
AKAP8_MOUSE	Akap8	physical	22083510
ANR17_MOUSE	Ankrd17	physical	22083510
ANXA2_MOUSE	Anxa2	physical	22083510
AP2M1_MOUSE	Ap2m1	physical	22083510
APLP2_MOUSE	Aplp2	physical	22083510
ARI1A_MOUSE	Arid1a	physical	22083510
ARI3B_MOUSE	Arid3b	physical	22083510
ASH2L_MOUSE	Ash2l	physical	22083510
AT1A1_MOUSE	Atp1a1	physical	22083510
ATX10_MOUSE	Atxn10	physical	22083510
PRC2B_MOUSE	Prrc2b	physical	22083510
BRD3_MOUSE	Brd3	physical	22083510
BRD4_MOUSE	Brd4	physical	22083510
BZW2_MOUSE	Bzw2	physical	22083510
CALU_MOUSE	Calu	physical	22083510
TCPB_MOUSE	Cct2	physical	22083510
TCPG_MOUSE	Cct3	physical	22083510
TCPD_MOUSE	Cct4	physical	22083510
TCPE_MOUSE	Cct5	physical	22083510
TCPH_MOUSE	Cct7	physical	22083510
CDC73_MOUSE	Cdc73	physical	22083510
CHD4_MOUSE	Chd4	physical	22083510
CKAP5_MOUSE	Ckap5	physical	22083510
NEUA_MOUSE	Cmas	physical	22083510
CNN2_MOUSE	Cnn2	physical	22083510
CNN3_MOUSE	Cnn3	physical	22083510
CNOT1_MOUSE	Cnot1	physical	22083510
COIA1_MOUSE	Col18a1	physical	22083510
COPB_MOUSE	Copb1	physical	22083510
CPSF1_MOUSE	Cpsf1	physical	22083510
CPSF2_MOUSE	Cpsf2	physical	22083510
CPSF6_MOUSE	Cpsf6	physical	22083510
CSK21_MOUSE	Csnk2a1	physical	22083510
CTBP2_MOUSE	Ctbp2	physical	22083510
CTNB1_MOUSE	Ctnnb1	physical	22083510
CUL4B_MOUSE	Cul4b	physical	22083510
ODB2_MOUSE	Dbt	physical	22083510
DDX4_MOUSE	Ddx4	physical	22083510
DDX47_MOUSE	Ddx47	physical	22083510
DNJA1_MOUSE	Dnaja1	physical	22083510
DNJA2_MOUSE	Dnaja2	physical	22083510
REQU_MOUSE	Dpf2	physical	22083510
DYHC1_MOUSE	Dync1h1	physical	22083510
EF2_MOUSE	Eef2	physical	22083510
EHD4_MOUSE	Ehd4	physical	22083510
ELAV1_MOUSE	Elavl1	physical	22083510
ERR2_MOUSE	Esrrb	physical	22083510
ERR3_MOUSE	Esrrg	physical	22083510
ERF1_MOUSE	Etf1	physical	22083510
FLNA_MOUSE	Flna	physical	22083510
FLNB_MOUSE	Flnb	physical	22083510
FRG1_MOUSE	Frg1	physical	22083510
P66A_MOUSE	Gatad2a	physical	22083510
P66B_MOUSE	Gatad2b	physical	22083510
GFAP_MOUSE	Gfap	physical	22083510
GGYF2_MOUSE	Gigyf2	physical	22083510
GLI2_MOUSE	Gli2	physical	22083510
GBB1_MOUSE	Gnb1	physical	22083510
T2EA_MOUSE	Gtf2e1	physical	22083510
GTF2I_MOUSE	Gtf2i	physical	22083510
ECHA_MOUSE	Hadha	physical	22083510
HCFC1_MOUSE	Hcfc1	physical	22083510
HDAC1_MOUSE	Hdac1	physical	22083510
HDGF_MOUSE	Hdgf	physical	22083510
HELLS_MOUSE	Hells	physical	22083510
HELZ_MOUSE	Helz	physical	22083510
H12_MOUSE	Hist1h1c	physical	22083510
HXK2_MOUSE	Hk2	physical	22083510
HNRPL_MOUSE	Hnrnpl	physical	22083510
HNRPU_MOUSE	Hnrnpu	physical	22083510
CH60_MOUSE	Hspd1	physical	22083510
PGBM_MOUSE	Hspg2	physical	22083510
IDHG1_MOUSE	Idh3g	physical	22083510
ILF3_MOUSE	Ilf3	physical	22083510
ILK_MOUSE	Ilk	physical	22083510
JHD2C_MOUSE	Jmjd1c	physical	22083510
KDM1A_MOUSE	Kdm1a	physical	22083510
KIF11_MOUSE	Kif11	physical	22083510
KIF4_MOUSE	Kif4	physical	22083510
LITD1_MOUSE	L1td1	physical	22083510
LAMA1_MOUSE	Lama1	physical	22083510
LAMB1_MOUSE	Lamb1	physical	22083510
LEO1_MOUSE	Leo1	physical	22083510
LIMS1_MOUSE	Lims1	physical	22083510
LRC40_MOUSE	Lrrc40	physical	22083510
LRC47_MOUSE	Lrrc47	physical	22083510
MATR3_MOUSE	Matr3	physical	22083510
MBD3_MOUSE	Mbd3	physical	22083510
MDC1_MOUSE	Mdc1	physical	22083510
AF10_MOUSE	Mllt10	physical	22083510
AFAD_MOUSE	Mllt4	physical	22083510
MSH2_MOUSE	Msh2	physical	22083510
MSH6_MOUSE	Msh6	physical	22083510
MTA2_MOUSE	Mta2	physical	22083510
MTA3_MOUSE	Mta3	physical	22083510
NACAM_MOUSE	Naca	physical	22083510
NACA_MOUSE	Naca	physical	22083510
NACC1_MOUSE	Nacc1	physical	22083510
NCOR2_MOUSE	Ncor2	physical	22083510
NEDD4_MOUSE	Nedd4	physical	22083510
NID2_MOUSE	Nid2	physical	22083510
NONO_MOUSE	Nono	physical	22083510
NUP93_MOUSE	Nup93	physical	22083510
OGT1_MOUSE	Ogt	physical	22083510
ORC2_MOUSE	Orc2	physical	22083510
P4HA1_MOUSE	P4ha1	physical	22083510
PAF1_MOUSE	Paf1	physical	22083510
PAK4_MOUSE	Pak4	physical	22083510
PCBP2_MOUSE	Pcbp2	physical	22083510
PLK1_MOUSE	Plk1	physical	22083510
PP1A_MOUSE	Ppp1ca	physical	22083510
PP1B_MOUSE	Ppp1cb	physical	22083510
PP1G_MOUSE	Ppp1cc	physical	22083510
PP1RA_MOUSE	Ppp1r10	physical	22083510
PRP4B_MOUSE	Prpf4b	physical	22083510
PSPC1_MOUSE	Pspc1	physical	22083510
PTBP2_MOUSE	Ptbp2	physical	22083510
RAD21_MOUSE	Rad21	physical	22083510
RAI14_MOUSE	Rai14	physical	22083510
RBBP5_MOUSE	Rbbp5	physical	22083510
RBBP7_MOUSE	Rbbp7	physical	22083510
SCAF8_MOUSE	Scaf8	physical	22083510
SPF45_MOUSE	Rbm17	physical	22083510
RCOR2_MOUSE	Rcor2	physical	22083510
RFC1_MOUSE	Rfc1	physical	22083510
RFC4_MOUSE	Rfc4	physical	22083510
RFC5_MOUSE	Rfc5	physical	22083510
RIF1_MOUSE	Rif1	physical	22083510
RING2_MOUSE	Rnf2	physical	22083510
RFA1_MOUSE	Rpa1	physical	22083510
RPN1_MOUSE	Rpn1	physical	22083510
RPN2_MOUSE	Rpn2	physical	22083510
RTN4_MOUSE	Rtn4	physical	22083510
SALL4_MOUSE	Sall4	physical	22083510
SP130_MOUSE	Sap130	physical	22083510
S30BP_MOUSE	Sap30bp	physical	22083510
SEPT2_MOUSE	Sept2	physical	22083510
SERPH_MOUSE	Serpinh1	physical	22083510
SF3A3_MOUSE	Sf3a3	physical	22083510
SHOC2_MOUSE	Shoc2	physical	22083510
SIR6_MOUSE	Sirt6	physical	22083510
SMCA2_MOUSE	Smarca2	physical	22083510
SMCA4_MOUSE	Smarca4	physical	22083510
SMCA5_MOUSE	Smarca5	physical	22083510
SNF5_MOUSE	Smarcb1	physical	22083510
SMRC1_MOUSE	Smarcc1	physical	22083510
SMRC2_MOUSE	Smarcc2	physical	22083510
SMCE1_MOUSE	Smarce1	physical	22083510
SMHD1_MOUSE	Smchd1	physical	22083510
SND1_MOUSE	Snd1	physical	22083510
SRP68_MOUSE	Srp68	physical	22083510
SSRP1_MOUSE	Ssrp1	physical	22083510
SDS3_MOUSE	Suds3	physical	22083510
SP16H_MOUSE	Supt16	physical	22083510
TAF1_MOUSE	Taf1	physical	22083510
TAOK1_MOUSE	Taok1	physical	22083510
TBP_MOUSE	Tbp	physical	22083510
TCRG1_MOUSE	Tcerg1	physical	22083510
AP2A_MOUSE	Tfap2a	physical	22083510
TCOF_MOUSE	Tcof1	physical	22083510
TCPA_MOUSE	Tcp1	physical	22083510
TDH_MOUSE	Tdh	physical	22083510
TET1_MOUSE	Tet1	physical	22083510
LAP2B_MOUSE	Tmpo	physical	22083510
LAP2A_MOUSE	Tmpo	physical	22083510
TOP2B_MOUSE	Top2b	physical	22083510
TOX4_MOUSE	Tox4	physical	22083510
TPR_MOUSE	Tpr	physical	22083510
TP53B_MOUSE	Trp53bp1	physical	22083510
UBP2L_MOUSE	Ubap2l	physical	22083510
RENT1_MOUSE	Upf1	physical	22083510
VRK1_MOUSE	Vrk1	physical	22083510
WAPL_MOUSE	Wapal	physical	22083510
SYWC_MOUSE	Wars	physical	22083510
WDR33_MOUSE	Wdr33	physical	22083510
WDR5_MOUSE	Wdr5	physical	22083510
TUT4_MOUSE	Zcchc11	physical	22083510
ZMYM2_MOUSE	Zmym2	physical	22083510
CDC20_MOUSE	Cdc20	physical	22084091
CTNB1_MOUSE	Ctnnb1	physical	23444350
NANOG_MOUSE	Nanog	physical	23444350
CADH1_MOUSE	Cdh1	physical	23444350
SALL4_MOUSE	Sall4	physical	23269686
OGT1_MOUSE	Ogt	physical	22608532
RYBP_MOUSE	Rybp	physical	28111200

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PO5F1_MOUSE

Related Literatures of Post-Translational Modification

Sumoylation
Reference	PubMed
"Sumoylation of Oct4 enhances its stability, DNA binding, andtransactivation."; Wei F., Schoeler H.R., Atchison M.L.; J. Biol. Chem. 282:21551-21560(2007). Cited for: SUMOYLATION AT LYS-118, MUTAGENESIS OF LYS-118, FUNCTION, ANDSUBCELLULAR LOCATION.	17525163 [Abstract]
"Post-translational modification of POU domain transcription factorOct-4 by SUMO-1."; Zhang Z., Liao B., Xu M., Jin Y.; FASEB J. 21:3042-3051(2007). Cited for: SUMOYLATION AT LYS-118, MUTAGENESIS OF LYS-118; GLU-120; LYS-215 ANDLYS-244, FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH UBE2I.	17496161 [Abstract]
"Inhibition of DNA binding of Sox2 by the SUMO conjugation."; Tsuruzoe S., Ishihara K., Uchimura Y., Watanabe S., Sekita Y.,Aoto T., Saitoh H., Yuasa Y., Niwa H., Kawasuji M., Baba H., Nakao M.; Biochem. Biophys. Res. Commun. 351:920-926(2006). Cited for: SUMOYLATION AT LYS-118, AND MUTAGENESIS OF LYS-118.	17097055 [Abstract]

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