ERR2_MOUSE - dbPTM
ERR2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERR2_MOUSE
UniProt AC Q61539
Protein Name Steroid hormone receptor ERR2 {ECO:0000305}
Gene Name Esrrb {ECO:0000312|MGI:MGI:1346832}
Organism Mus musculus (Mouse).
Sequence Length 433
Subcellular Localization Nucleus . Cytoplasm . Chromosome .
Protein Description Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcriptional activity. [PubMed: 27601327]
Protein Sequence MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGIALSTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYNCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLNLPISPPAKKPLTKIVSNLLGVEQDKLYAMPPNDIPEGDIKALTTLCELADRELVFLINWAKHIPGFPSLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLDLYRAILQLVRRYKKLKVEKEEFMILKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25O-linked_GlycosylationTEPSSPSSGIDALSH
CCCCCCCCCCCCHHC		43.0531492838
75PhosphorylationGGNPCRKSYEDCTSG
CCCCCCCCHHHHCCC		17.8822006019
81PhosphorylationKSYEDCTSGIMEDSA
CCHHHHCCCHHCCHH		32.4328973931
149UbiquitinationTNECEITKRRRKSCQ
CCCCCHHHHHHHHHH		49.95-
154PhosphorylationITKRRRKSCQACRFM
HHHHHHHHHHHHHHH		15.06-
170UbiquitinationCLKVGMLKEGVRLDR
HHHHCCCCCCCCHHH		43.46-
194PhosphorylationRRLDSENSPYLNLPI
HHCCCCCCCCCCCCC		15.7421082442
202PhosphorylationPYLNLPISPPAKKPL
CCCCCCCCCCCCCCH		23.9226239621
211UbiquitinationPAKKPLTKIVSNLLG
CCCCCHHHHHHHHHC		49.12-
214PhosphorylationKPLTKIVSNLLGVEQ
CCHHHHHHHHHCCCC		25.8222006019
391UbiquitinationEEPRRAGKLLLTLPL
CCCHHHHHHHHHHHH		39.15-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERR2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERR2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERR2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PO5F1_MOUSEPou5f1physical
18662995
SMRC1_MOUSESmarcc1physical
20362541
ARI1A_MOUSEArid1aphysical
20362541
SMCA4_MOUSESmarca4physical
20362541
SMRD1_MOUSESmarcd1physical
20362541
EP400_MOUSEEp400physical
20362541
YETS4_MOUSEYeats4physical
20362541
DMAP1_MOUSEDmap1physical
20362541
BRD8_MOUSEBrd8physical
20362541
ING3_MOUSEIng3physical
20362541
MRGBP_MOUSEMrgbpphysical
20362541
CHD4_MOUSEChd4physical
20362541
P66A_MOUSEGatad2aphysical
20362541
MTA2_MOUSEMta2physical
20362541
MTA1_MOUSEMta1physical
20362541
P66B_MOUSEGatad2bphysical
20362541
MTA3_MOUSEMta3physical
20362541
MBD3_MOUSEMbd3physical
20362541
HDAC1_MOUSEHdac1physical
20362541
HDAC2_MOUSEHdac2physical
20362541
RBBP4_MOUSERbbp4physical
20362541
MED14_MOUSEMed14physical
20362541
MED12_MOUSEMed12physical
20362541
MED23_MOUSEMed23physical
20362541
MED24_MOUSEMed24physical
20362541
MED17_MOUSEMed17physical
20362541
MED1_MOUSEMed1physical
20362541
MED16_MOUSEMed16physical
20362541
MED13_MOUSEMed13physical
20362541
MED27_MOUSEMed27physical
20362541
MED25_MOUSEMed25physical
20362541
MD13L_MOUSEMed13lphysical
20362541
MED4_MOUSEMed4physical
20362541
MED26_MOUSEMed26physical
20362541
MED6_MOUSEMed6physical
20362541
MED8_MOUSEMed8physical
20362541
CCNC_MOUSECcncphysical
20362541
MED30_MOUSEMed30physical
20362541
MED7_MOUSEMed7physical
20362541
MED29_MOUSEMed29physical
20362541
CDK8_MOUSECdk8physical
20362541
MED18_MOUSEMed18physical
20362541
MED19_MOUSEMed19physical
20362541
RPB1_MOUSEPolr2aphysical
20362541
RPB2_MOUSEPolr2bphysical
20362541
RPB7_MOUSEPolr2gphysical
20362541
TAF9_MOUSETaf9physical
20362541
TAF6_MOUSETaf6physical
20362541
TAF10_MOUSETaf10physical
20362541
TBP_MOUSETbpphysical
20362541
WDR5_MOUSEWdr5physical
20362541
HCFC1_MOUSEHcfc1physical
20362541
ASH2L_MOUSEAsh2lphysical
20362541
RBBP5_MOUSERbbp5physical
20362541
SALL4_MOUSESall4physical
20362541
NR0B1_MOUSENr0b1physical
20362541
TF2L1_MOUSETfcp2l1physical
20362541
FKB15_MOUSEFkbp15physical
20362541
ERR1_MOUSEEsrraphysical
20362541
UBIP1_MOUSEUbp1physical
20362541
NRIP1_MOUSENrip1physical
20362541
CDK1_MOUSECdk1physical
20362541
ZBTB9_MOUSEZbtb9physical
20362541
SMCA5_MOUSESmarca5physical
20362541
WIZ_MOUSEWizphysical
20362541
REQU_MOUSEDpf2physical
20362541
JHD2C_MOUSEJmjd1cphysical
20362541
TFCP2_MOUSETfcp2physical
20362541
LMBL2_MOUSEL3mbtl2physical
20362541
PO5F1_MOUSEPou5f1physical
20362541
KAT8_MOUSEKat8physical
20362541
EHMT1_MOUSEEhmt1physical
20362541
RIF1_MOUSERif1physical
20362541
OGT1_MOUSEOgtphysical
20362541
CO4A5_HUMANCOL4A5physical
26496610
CRY1_HUMANCRY1physical
26496610
ERR1_HUMANESRRAphysical
26496610
MUTA_HUMANMUTphysical
26496610
MYH1_HUMANMYH1physical
26496610
TACC1_HUMANTACC1physical
26496610
WASL_HUMANWASLphysical
26496610
DCAF1_HUMANVPRBPphysical
26496610
ACINU_HUMANACIN1physical
26496610
SIR1_HUMANSIRT1physical
26496610
NECT3_HUMANPVRL3physical
26496610
HERC4_HUMANHERC4physical
26496610
ZN638_HUMANZNF638physical
26496610
CI072_HUMANC9orf72physical
26496610
SOX2_MOUSESox2physical
23169531
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERR2_MOUSE

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Related Literatures of Post-Translational Modification

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