TAF6_MOUSE - dbPTM
TAF6_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TAF6_MOUSE
UniProt AC Q62311
Protein Name Transcription initiation factor TFIID subunit 6
Gene Name Taf6
Organism Mus musculus (Mouse).
Sequence Length 678
Subcellular Localization Nucleus.
Protein Description TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors (By similarity)..
Protein Sequence MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGSGSVQKYIVVSLPPTGEGKGGPPSHPSPVPPSSSSPSPLGGSTLCGGKQEAGDSPPPAPGTPKANGSQPTGPGSPQPAL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
120PhosphorylationDLSDIINTPLPRVPL
CHHHHCCCCCCCCCH		18.78-
137PhosphorylationCLKAHWLSIEGCQPA
HHHHHEEEECCCCCC		17.2525159016
248PhosphorylationEALQSIATDPGLYQM
HHHHHHCCCHHHHHH		40.85-
253PhosphorylationIATDPGLYQMLPRFS
HCCCHHHHHHHHHHH		9.59-
260PhosphorylationYQMLPRFSTFISEGV
HHHHHHHHHHHCCCC		24.5622802335
261PhosphorylationQMLPRFSTFISEGVR
HHHHHHHHHHCCCCC		23.4422802335
264PhosphorylationPRFSTFISEGVRVNV
HHHHHHHCCCCCCEE		24.89-
294PhosphorylationKALMDNPTLYLEKYV
HHHHHCCHHHHHHHH		34.0029895711
296PhosphorylationLMDNPTLYLEKYVHE
HHHCCHHHHHHHHHH		18.4529895711
345PhosphorylationAQICKHFSTTTNNIQ
HHHHHHHHCCCCCHH		25.2722802335
353PhosphorylationTTTNNIQSRITKTFT
CCCCCHHHHHHHHHC		23.1222802335
481O-linked_GlycosylationAQQVNRTTLTITQPR
HHHCCCCEEEEEECC		20.7551588483
524MethylationVQTLVSARAAAPPQP
HHHHHHHHHCCCCCC		19.7724129315
532PhosphorylationAAAPPQPSPPPTKFI
HCCCCCCCCCCCEEE		44.8026824392
536PhosphorylationPQPSPPPTKFIVMSS
CCCCCCCCEEEEEEC		44.3425619855
568PhosphorylationPGSGSTTTSPVTTTV
CCCCCCCCCCCCCCC		30.99-
589PhosphorylationVKLVSTATTAPPSTA
EEHHHCCCCCCCCCC		24.47-
594PhosphorylationTATTAPPSTAPAGSG
CCCCCCCCCCCCCCC		35.82-
623PhosphorylationEGKGGPPSHPSPVPP
CCCCCCCCCCCCCCC		51.6825619855
626PhosphorylationGGPPSHPSPVPPSSS
CCCCCCCCCCCCCCC		32.8621082442
631PhosphorylationHPSPVPPSSSSPSPL
CCCCCCCCCCCCCCC		36.4625619855
632PhosphorylationPSPVPPSSSSPSPLG
CCCCCCCCCCCCCCC		40.3825619855
633PhosphorylationSPVPPSSSSPSPLGG
CCCCCCCCCCCCCCC		51.0825619855
634PhosphorylationPVPPSSSSPSPLGGS
CCCCCCCCCCCCCCC		31.2021082442
636PhosphorylationPPSSSSPSPLGGSTL
CCCCCCCCCCCCCCC		34.4025619855
641PhosphorylationSPSPLGGSTLCGGKQ
CCCCCCCCCCCCCCC		19.1925619855
642PhosphorylationPSPLGGSTLCGGKQE
CCCCCCCCCCCCCCC		29.3725619855
653PhosphorylationGKQEAGDSPPPAPGT
CCCCCCCCCCCCCCC		38.0925521595
660PhosphorylationSPPPAPGTPKANGSQ
CCCCCCCCCCCCCCC		22.1325521595
666PhosphorylationGTPKANGSQPTGPGS
CCCCCCCCCCCCCCC		32.5625619855
669PhosphorylationKANGSQPTGPGSPQP
CCCCCCCCCCCCCCC		48.6625619855
673PhosphorylationSQPTGPGSPQPAL--
CCCCCCCCCCCCC--		24.4025521595
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TAF6_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TAF6_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TAF6_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TAF6_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TAF6_MOUSE

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Related Literatures of Post-Translational Modification

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