| UniProt ID | MTA2_MOUSE | |
|---|---|---|
| UniProt AC | Q9R190 | |
| Protein Name | Metastasis-associated protein MTA2 | |
| Gene Name | Mta2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 668 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.. | |
| Protein Sequence | MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLADSNAREFEEESKQPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDILNQYLDKEDCFFYSLVFDPVQKTLLADQGEIRVGCKFQAEIPDRLAEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISVGSKPGMNGAGFQKGLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPTQLEGAARGTTEPHSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRLARRMCRDLLQPRRAARRPYAPINANAIKAECSIRLPKAAKTPLKIHPLVRLPLATIVKDLVAQAPLKPKTPRGTKTPINRNQLTQNRGLGGIMVKRSYETMAGAGVPFSANGRPLASGIRSSSQPAAKRQKLNPADAPNPVVFVATKDTRALRKALTHLEMRRAARRPNLPLKVKPTLMTVRPPVPLPASSHPASTNEPIVLED | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Ubiquitination | RRIEELNKTANGNVE HHHHHHHHHCCCCEE | 62.73 | - | |
| 52 | Phosphorylation | LFRRRDISSSLNSLA EEECCCCHHHHHHHH | 20.40 | 25619855 | |
| 53 | Phosphorylation | FRRRDISSSLNSLAD EECCCCHHHHHHHHH | 38.90 | 25619855 | |
| 54 | Phosphorylation | RRRDISSSLNSLADS ECCCCHHHHHHHHHH | 25.44 | 25521595 | |
| 57 | Phosphorylation | DISSSLNSLADSNAR CCHHHHHHHHHHCHH | 30.17 | 25619855 | |
| 61 | Phosphorylation | SLNSLADSNAREFEE HHHHHHHHCHHHHHH | 27.12 | 25619855 | |
| 71 | Ubiquitination | REFEEESKQPGVSEQ HHHHHHHCCCCCCHH | 64.89 | - | |
| 122 | Ubiquitination | DILNQYLDKEDCFFY HHHHHHCCHHHCEEE | 47.57 | 27667366 | |
| 152 | Acetylation | GEIRVGCKFQAEIPD CCEEEEEEEEEECCH | 34.28 | 23806337 | |
| 152 | Ubiquitination | GEIRVGCKFQAEIPD CCEEEEEEEEEECCH | 34.28 | - | |
| 152 | Malonylation | GEIRVGCKFQAEIPD CCEEEEEEEEEECCH | 34.28 | 26320211 | |
| 173 | Ubiquitination | SDNRNQQKMEMKVWD CCCHHHHCCEEEECC | 27.36 | - | |
| 194 | Ubiquitination | DRQIDQFLVVARAVG HHHHHHHHHHHHHHH | 2.23 | 27667366 | |
| 209 | S-nitrosocysteine | TFARALDCSSSIRQP HHHHHHCCCCCCCCC | 4.40 | - | |
| 209 | S-nitrosylation | TFARALDCSSSIRQP HHHHHHCCCCCCCCC | 4.40 | 20925432 | |
| 210 | Phosphorylation | FARALDCSSSIRQPS HHHHHCCCCCCCCCC | 27.13 | 21454597 | |
| 211 | Phosphorylation | ARALDCSSSIRQPSL HHHHCCCCCCCCCCH | 35.79 | 21454597 | |
| 217 | Phosphorylation | SSSIRQPSLHMSAAA CCCCCCCCHHHHHHH | 23.67 | 27566939 | |
| 221 | Phosphorylation | RQPSLHMSAAAASRD CCCCHHHHHHHHHCC | 12.19 | 21454597 | |
| 341 | Ubiquitination | VYIPTYTKPNPNQII EECCCCCCCCCCCEE | 32.17 | 27667366 | |
| 392 | Ubiquitination | NMQCRLCASCWIYWK CHHCCHHHHHHHHHH | 16.59 | 27667366 | |
| 406 | Phosphorylation | KKYGGLKTPTQLEGA HHCCCCCCCCCCCHH | 36.29 | 27600695 | |
| 427 | Phosphorylation | PHSRGHLSRPEAQSL CCCCCCCCCHHHHCC | 39.86 | 25619855 | |
| 433 | Phosphorylation | LSRPEAQSLSPYTTS CCCHHHHCCCCCCCC | 37.55 | 27742792 | |
| 435 | Phosphorylation | RPEAQSLSPYTTSAN CHHHHCCCCCCCCHH | 22.55 | 27087446 | |
| 437 | Phosphorylation | EAQSLSPYTTSANRA HHHCCCCCCCCHHHH | 21.19 | 25619855 | |
| 438 | Phosphorylation | AQSLSPYTTSANRAK HHCCCCCCCCHHHHH | 20.05 | 25619855 | |
| 439 | Phosphorylation | QSLSPYTTSANRAKL HCCCCCCCCHHHHHH | 21.72 | 25619855 | |
| 440 | Phosphorylation | SLSPYTTSANRAKLL CCCCCCCCHHHHHHH | 18.75 | 25619855 | |
| 453 | Phosphorylation | LLAKNRQTFLLQTTK HHHHCCCHHHHHHHH | 17.02 | 29176673 | |
| 460 | Acetylation | TFLLQTTKLTRLARR HHHHHHHHHHHHHHH | 51.77 | 23806337 | |
| 464 | Ubiquitination | QTTKLTRLARRMCRD HHHHHHHHHHHHHHH | 3.51 | 27667366 | |
| 505 | Phosphorylation | RLPKAAKTPLKIHPL ECCCCCCCCCCCCCC | 29.18 | - | |
| 508 | Acetylation | KAAKTPLKIHPLVRL CCCCCCCCCCCCCCC | 39.92 | 22826441 | |
| 508 | Ubiquitination | KAAKTPLKIHPLVRL CCCCCCCCCCCCCCC | 39.92 | - | |
| 522 | Acetylation | LPLATIVKDLVAQAP CCHHHHHHHHHHCCC | 41.30 | 23806337 | |
| 531 | Acetylation | LVAQAPLKPKTPRGT HHHCCCCCCCCCCCC | 43.33 | 23806337 | |
| 534 | Phosphorylation | QAPLKPKTPRGTKTP CCCCCCCCCCCCCCC | 27.09 | 26824392 | |
| 539 | Malonylation | PKTPRGTKTPINRNQ CCCCCCCCCCCCHHH | 55.94 | 26320211 | |
| 540 | Phosphorylation | KTPRGTKTPINRNQL CCCCCCCCCCCHHHC | 29.28 | - | |
| 559 | Acetylation | GLGGIMVKRSYETMA CCCCEEEEECEECCC | 20.46 | 7614651 | |
| 573 | Phosphorylation | AGAGVPFSANGRPLA CCCCCCCCCCCCCCC | 18.11 | 29514104 | |
| 611 | Ubiquitination | PVVFVATKDTRALRK CEEEEEECCHHHHHH | 47.57 | 27667366 | |
| 611 | Acetylation | PVVFVATKDTRALRK CEEEEEECCHHHHHH | 47.57 | 7629397 | |
| 618 | Acetylation | KDTRALRKALTHLEM CCHHHHHHHHHHHHH | 48.90 | 7629407 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MTA2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MTA2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTA2_MOUSE !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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