dbPTM

P66A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	P66A_HUMAN
UniProt AC	Q86YP4
Protein Name	Transcriptional repressor p66-alpha
Gene Name	GATAD2A
Organism	Homo sapiens (Human).
Sequence Length	633
Subcellular Localization	Nucleus speckle . Speckled nuclear localization requires both CR1 and CR2 regions.
Protein Description	Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B..
Protein Sequence	MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	RALERDPTEDDVESK HHHHCCCCHHHHHHH	57.23	23917254
26	Phosphorylation	PTEDDVESKKIKMER CCHHHHHHHHHHHHC	38.81	22985185
27	Acetylation	TEDDVESKKIKMERG CHHHHHHHHHHHHCC	45.04	25953088
30	Sumoylation	DVESKKIKMERGLLA HHHHHHHHHHCCCCH	43.52	-
30	Sumoylation	DVESKKIKMERGLLA HHHHHHHHHHCCCCH	43.52	-
38	Phosphorylation	MERGLLASDLNTDGD HHCCCCHHHCCCCCC	42.47	29978859
42	Phosphorylation	LLASDLNTDGDMRVT CCHHHCCCCCCCCCC	48.97	29255136
46	Sulfoxidation	DLNTDGDMRVTPEPG HCCCCCCCCCCCCCC	4.55	21406390
49	Phosphorylation	TDGDMRVTPEPGAGP CCCCCCCCCCCCCCC	16.15	19664994
57	Phosphorylation	PEPGAGPTQGLLRAT CCCCCCCCHHHHHHH	34.06	29978859
64	Phosphorylation	TQGLLRATEATAMAM CHHHHHHHHHHHHHC	21.51	27251275
67	Phosphorylation	LLRATEATAMAMGRG HHHHHHHHHHHCCCC	15.67	27251275
73	Methylation	ATAMAMGRGEGLVGD HHHHHCCCCCCCCCC	27.23	-
85	Sulfoxidation	VGDGPVDMRTSHSDM CCCCCCCCCCCHHHC	5.25	21406390
87	Phosphorylation	DGPVDMRTSHSDMKS CCCCCCCCCHHHCCC	24.93	24719451
88	Phosphorylation	GPVDMRTSHSDMKSE CCCCCCCCHHHCCCC	15.61	24719451
90	Phosphorylation	VDMRTSHSDMKSERR CCCCCCHHHCCCCCC	38.88	27251275
93	Sumoylation	RTSHSDMKSERRPPS CCCHHHCCCCCCCCC	54.90	-
93	Sumoylation	RTSHSDMKSERRPPS CCCHHHCCCCCCCCC	54.90	28112733
94	Phosphorylation	TSHSDMKSERRPPSP CCHHHCCCCCCCCCC	29.69	21406692
100	Phosphorylation	KSERRPPSPDVIVLS CCCCCCCCCCEEEEC	36.09	29255136
107	Phosphorylation	SPDVIVLSDNEQPSS CCCEEEECCCCCCCC	27.74	29255136
113	Phosphorylation	LSDNEQPSSPRVNGL ECCCCCCCCCCCCCE	53.31	29255136
114	Phosphorylation	SDNEQPSSPRVNGLT CCCCCCCCCCCCCEE	24.33	29255136
121	Phosphorylation	SPRVNGLTTVALKET CCCCCCEEEEEEEEC	22.18	22115753
122	Phosphorylation	PRVNGLTTVALKETS CCCCCEEEEEEEECC	14.61	22115753
128	Phosphorylation	TTVALKETSTEALMK EEEEEEECCHHHHHH	39.08	24732914
129	Phosphorylation	TVALKETSTEALMKS EEEEEECCHHHHHHC	25.91	21815630
130	Phosphorylation	VALKETSTEALMKSS EEEEECCHHHHHHCC	32.47	30624053
135	Ubiquitination	TSTEALMKSSPEERE CCHHHHHHCCHHHHH	48.94	-
135	Ubiquitination	TSTEALMKSSPEERE CCHHHHHHCCHHHHH	48.94	-
136	Phosphorylation	STEALMKSSPEERER CHHHHHHCCHHHHHH	36.84	24732914
137	Phosphorylation	TEALMKSSPEERERM HHHHHHCCHHHHHHH	30.71	24732914
153	Methylation	KQLKEELRLEEAKLV HHHHHHHCHHHHHHH	43.25	-
158	Ubiquitination	ELRLEEAKLVLLKKL HHCHHHHHHHHHHHH	42.27	-
172	Acetylation	LRQSQIQKEATAQKP HHHHHHHHHHHCCCC	51.44	7366045
175	Phosphorylation	SQIQKEATAQKPTGS HHHHHHHHCCCCCCC	30.61	21712546
178	Ubiquitination	QKEATAQKPTGSVGS HHHHHCCCCCCCCCC	41.92	-
178	Sumoylation	QKEATAQKPTGSVGS HHHHHCCCCCCCCCC	41.92	28112733
178	Ubiquitination	QKEATAQKPTGSVGS HHHHHCCCCCCCCCC	41.92	-
180	Phosphorylation	EATAQKPTGSVGSTV HHHCCCCCCCCCCEE	49.47	22115753
182	O-linked_Glycosylation	TAQKPTGSVGSTVTT HCCCCCCCCCCEECC	26.28	30059200
182	Phosphorylation	TAQKPTGSVGSTVTT HCCCCCCCCCCEECC	26.28	22115753
185	Phosphorylation	KPTGSVGSTVTTPPP CCCCCCCCEECCCCC	19.97	30266825
186	Phosphorylation	PTGSVGSTVTTPPPL CCCCCCCEECCCCCC	18.88	30266825
188	Phosphorylation	GSVGSTVTTPPPLVR CCCCCEECCCCCCCC	33.40	30266825
189	Phosphorylation	SVGSTVTTPPPLVRG CCCCEECCCCCCCCC	29.48	25159151
204	Ubiquitination	TQNIPAGKPSLQTSS CCCCCCCCCCCCCCC	33.27	-
204	Acetylation	TQNIPAGKPSLQTSS CCCCCCCCCCCCCCC	33.27	26051181
204	Sumoylation	TQNIPAGKPSLQTSS CCCCCCCCCCCCCCC	33.27	28112733
204	Ubiquitination	TQNIPAGKPSLQTSS CCCCCCCCCCCCCCC	33.27	-
206	Phosphorylation	NIPAGKPSLQTSSAR CCCCCCCCCCCCCCC	36.27	28555341
209	O-linked_Glycosylation	AGKPSLQTSSARMPG CCCCCCCCCCCCCCC	29.91	30059200
210	O-linked_Glycosylation	GKPSLQTSSARMPGS CCCCCCCCCCCCCCC	14.72	30059200
211	Phosphorylation	KPSLQTSSARMPGSV CCCCCCCCCCCCCCC	24.23	20068231
213	Methylation	SLQTSSARMPGSVIP CCCCCCCCCCCCCCC	33.50	-
214	Sulfoxidation	LQTSSARMPGSVIPP CCCCCCCCCCCCCCC	4.39	21406390
217	Phosphorylation	SSARMPGSVIPPPLV CCCCCCCCCCCCCEE	15.82	22210691
225	Methylation	VIPPPLVRGGQQASS CCCCCEECCCCCCHH	51.73	-
233	Ubiquitination	GGQQASSKLGPQASS CCCCCHHCCCCCCCC	55.77	-
233	Acetylation	GGQQASSKLGPQASS CCCCCHHCCCCCCCC	55.77	25953088
233	Sumoylation	GGQQASSKLGPQASS CCCCCHHCCCCCCCC	55.77	28112733
233	Ubiquitination	GGQQASSKLGPQASS CCCCCHHCCCCCCCC	55.77	-
239	Phosphorylation	SKLGPQASSQVVMPP HCCCCCCCCCCCCCC	18.96	26714015
240	Phosphorylation	KLGPQASSQVVMPPL CCCCCCCCCCCCCCC	29.97	26714015
244	Sulfoxidation	QASSQVVMPPLVRGA CCCCCCCCCCCCCCH	2.73	21406390
249	Dimethylation	VVMPPLVRGAQQIHS CCCCCCCCCHHHHHH	42.27	-
249	Methylation	VVMPPLVRGAQQIHS CCCCCCCCCHHHHHH	42.27	24129315
256	Phosphorylation	RGAQQIHSIRQHSST CCHHHHHHHHHCCCC	22.54	23401153
258	Dimethylation	AQQIHSIRQHSSTGP HHHHHHHHHCCCCCC	31.04	-
258	Methylation	AQQIHSIRQHSSTGP HHHHHHHHHCCCCCC	31.04	24129315
261	Phosphorylation	IHSIRQHSSTGPPPL HHHHHHCCCCCCCCE	22.66	23312004
262	Phosphorylation	HSIRQHSSTGPPPLL HHHHHCCCCCCCCEE	34.95	23312004
263	Phosphorylation	SIRQHSSTGPPPLLL HHHHCCCCCCCCEEE	57.64	23312004
273	Dimethylation	PPLLLAPRASVPSVQ CCEEECCCCCCCCEE	33.61	-
273	Methylation	PPLLLAPRASVPSVQ CCEEECCCCCCCCEE	33.61	24129315
275	Phosphorylation	LLLAPRASVPSVQIQ EEECCCCCCCCEEEC	35.52	29978859
278	Phosphorylation	APRASVPSVQIQGQR CCCCCCCCEEECCEE	25.21	23186163
285	Methylation	SVQIQGQRIIQQGLI CEEECCEEHHHCCCE	34.50	24129315
293	Methylation	IIQQGLIRVANVPNT HHHCCCEEEECCCCC	26.91	-
300	Phosphorylation	RVANVPNTSLLVNIP EEECCCCCEEEEECC	18.06	28122231
301	Phosphorylation	VANVPNTSLLVNIPQ EECCCCCEEEEECCC	26.75	28122231
310	Phosphorylation	LVNIPQPTPASLKGT EEECCCCCCCCCCCC	26.66	28122231
313	Phosphorylation	IPQPTPASLKGTTAT CCCCCCCCCCCCCCC	31.64	20068231
317	O-linked_Glycosylation	TPASLKGTTATSAQA CCCCCCCCCCCCCCC	16.21	30059200
317	Phosphorylation	TPASLKGTTATSAQA CCCCCCCCCCCCCCC	16.21	24732914
318	O-linked_Glycosylation	PASLKGTTATSAQAN CCCCCCCCCCCCCCC	36.28	30059200
318	Phosphorylation	PASLKGTTATSAQAN CCCCCCCCCCCCCCC	36.28	24732914
320	Phosphorylation	SLKGTTATSAQANST CCCCCCCCCCCCCCC	23.62	24732914
321	O-linked_Glycosylation	LKGTTATSAQANSTP CCCCCCCCCCCCCCC	18.87	30059200
321	Phosphorylation	LKGTTATSAQANSTP CCCCCCCCCCCCCCC	18.87	24732914
326	O-linked_Glycosylation	ATSAQANSTPTSVAS CCCCCCCCCCCCHHH	38.49	30059200
326	Phosphorylation	ATSAQANSTPTSVAS CCCCCCCCCCCCHHH	38.49	24732914
327	O-linked_Glycosylation	TSAQANSTPTSVASV CCCCCCCCCCCHHHH	30.32	30059200
327	Phosphorylation	TSAQANSTPTSVASV CCCCCCCCCCCHHHH	30.32	25159151
329	O-linked_Glycosylation	AQANSTPTSVASVVT CCCCCCCCCHHHHHH	35.60	30059200
329	Phosphorylation	AQANSTPTSVASVVT CCCCCCCCCHHHHHH	35.60	28176443
330	O-linked_Glycosylation	QANSTPTSVASVVTS CCCCCCCCHHHHHHC	19.52	30059200
330	Phosphorylation	QANSTPTSVASVVTS CCCCCCCCHHHHHHC	19.52	29255136
333	O-linked_Glycosylation	STPTSVASVVTSAES CCCCCHHHHHHCCCC	18.24	30059200
333	Phosphorylation	STPTSVASVVTSAES CCCCCHHHHHHCCCC	18.24	29255136
336	O-linked_Glycosylation	TSVASVVTSAESPAS CCHHHHHHCCCCHHH	21.77	30059200
336	Phosphorylation	TSVASVVTSAESPAS CCHHHHHHCCCCHHH	21.77	29255136
337	Phosphorylation	SVASVVTSAESPASR CHHHHHHCCCCHHHH	20.59	29255136
340	Phosphorylation	SVVTSAESPASRQAA HHHHCCCCHHHHHHH	26.03	29255136
343	O-linked_Glycosylation	TSAESPASRQAAAKL HCCCCHHHHHHHHHH	28.45	30059200
343	Phosphorylation	TSAESPASRQAAAKL HCCCCHHHHHHHHHH	28.45	29255136
349	Ubiquitination	ASRQAAAKLALRKQL HHHHHHHHHHHHHHH	29.57	-
404	Sulfoxidation	LLETQGRMSAATVLS HHHHCCCCCHHHHHC	4.01	21406390
405	Phosphorylation	LETQGRMSAATVLSR HHHCCCCCHHHHHCC	17.25	20068231
411	Phosphorylation	MSAATVLSREPYMCA CCHHHHHCCCCEEEC	30.20	20068230
421	Ubiquitination	PYMCAQCKTDFTCRW CEEECCCCCCCCCCC	38.76	-
422	Ubiquitination	YMCAQCKTDFTCRWR EEECCCCCCCCCCCC	43.93	-
432	Acetylation	TCRWREEKSGAIMCE CCCCCHHCCCCEEEE	49.81	26051181
432	Ubiquitination	TCRWREEKSGAIMCE CCCCCHHCCCCEEEE	49.81	-
451	Sumoylation	TNQKKALKVEHTSRL CCHHHCCCCHHHHHH	50.89	-
451	Sumoylation	TNQKKALKVEHTSRL CCHHHCCCCHHHHHH	50.89	-
452	Ubiquitination	NQKKALKVEHTSRLK CHHHCCCCHHHHHHH	7.29	-
455	Phosphorylation	KALKVEHTSRLKAAF HCCCCHHHHHHHHHH	11.31	20068231
456	Phosphorylation	ALKVEHTSRLKAAFV CCCCHHHHHHHHHHH	37.21	20068231
464	Sumoylation	RLKAAFVKALQQEQE HHHHHHHHHHHHHHH	36.60	28112733
464	Ubiquitination	RLKAAFVKALQQEQE HHHHHHHHHHHHHHH	36.60	21890473
464 (in isoform 1)	Ubiquitination	-	36.60	21890473
464 (in isoform 2)	Ubiquitination	-	36.60	21890473
465	Ubiquitination	LKAAFVKALQQEQEI HHHHHHHHHHHHHHH	12.80	21890473
487	Sumoylation	GTAPAQAKAEPTAAP CCCCHHHCCCCCCCC	41.00	-
487	Acetylation	GTAPAQAKAEPTAAP CCCCHHHCCCCCCCC	41.00	26051181
487	Sumoylation	GTAPAQAKAEPTAAP CCCCHHHCCCCCCCC	41.00	28112733
487	Ubiquitination	GTAPAQAKAEPTAAP CCCCHHHCCCCCCCC	41.00	-
488	Ubiquitination	TAPAQAKAEPTAAPH CCCHHHCCCCCCCCC	30.89	-
491	O-linked_Glycosylation	AQAKAEPTAAPHPVL HHHCCCCCCCCCHHH	27.27	OGP
499	Ubiquitination	AAPHPVLKQVIKPRR CCCCHHHHHHHCCCH	42.63	-
500	Ubiquitination	APHPVLKQVIKPRRK CCCHHHHHHHCCCHH	37.70	-
512	Phosphorylation	RRKLAFRSGEARDWS CHHHCCCCCCCCCCC	34.23	25159151
527	Phosphorylation	NGAVLQASSQLSRGS CCCEEEECCHHCCCC	12.98	18776048
528	Phosphorylation	GAVLQASSQLSRGSA CCEEEECCHHCCCCC	37.85	-
531	Phosphorylation	LQASSQLSRGSATTP EEECCHHCCCCCCCC	27.27	18776048
532	Methylation	QASSQLSRGSATTPR EECCHHCCCCCCCCC	52.24	-
534	Phosphorylation	SSQLSRGSATTPRGV CCHHCCCCCCCCCCE	22.72	21955146
537	Phosphorylation	LSRGSATTPRGVLHT HCCCCCCCCCCEEEE	15.65	18776048
539	Asymmetric dimethylarginine	RGSATTPRGVLHTFS CCCCCCCCCEEEECC	45.84	-
539	Methylation	RGSATTPRGVLHTFS CCCCCCCCCEEEECC	45.84	24129315
544	Phosphorylation	TPRGVLHTFSPSPKL CCCCEEEECCCCHHH	22.96	29255136
546	Phosphorylation	RGVLHTFSPSPKLQN CCEEEECCCCHHHCC	26.14	29255136
548	Phosphorylation	VLHTFSPSPKLQNSA EEEECCCCHHHCCCH	33.21	29255136
550	Sumoylation	HTFSPSPKLQNSASA EECCCCHHHCCCHHC	68.02	-
550	Acetylation	HTFSPSPKLQNSASA EECCCCHHHCCCHHC	68.02	26051181
550	Methylation	HTFSPSPKLQNSASA EECCCCHHHCCCHHC	68.02	-
550	Sumoylation	HTFSPSPKLQNSASA EECCCCHHHCCCHHC	68.02	28112733
550	Ubiquitination	HTFSPSPKLQNSASA EECCCCHHHCCCHHC	68.02	-
551	Ubiquitination	TFSPSPKLQNSASAT ECCCCHHHCCCHHCH	7.09	-
554	Phosphorylation	PSPKLQNSASATALV CCHHHCCCHHCHHHH	15.61	25159151
556	Phosphorylation	PKLQNSASATALVSR HHHCCCHHCHHHHCC	26.44	30576142
558	Phosphorylation	LQNSASATALVSRTG HCCCHHCHHHHCCCC	20.30	23312004
568	Phosphorylation	VSRTGRHSERTVSAG HCCCCCCCEEEEECC	27.67	20068231
571	Phosphorylation	TGRHSERTVSAGKGS CCCCCEEEEECCCCC	18.11	20068231
573	Phosphorylation	RHSERTVSAGKGSAT CCCEEEEECCCCCCC	30.59	20068231
576	Sumoylation	ERTVSAGKGSATSNW EEEEECCCCCCCCCC	49.78	-
576	Acetylation	ERTVSAGKGSATSNW EEEEECCCCCCCCCC	49.78	26051181
576	Sumoylation	ERTVSAGKGSATSNW EEEEECCCCCCCCCC	49.78	-
576	Ubiquitination	ERTVSAGKGSATSNW EEEEECCCCCCCCCC	49.78	-
577	Ubiquitination	RTVSAGKGSATSNWK EEEECCCCCCCCCCE	22.92	-
578	Phosphorylation	TVSAGKGSATSNWKK EEECCCCCCCCCCEE	31.68	20068231
580	Phosphorylation	SAGKGSATSNWKKTP ECCCCCCCCCCEECC	25.04	20068231
581	Phosphorylation	AGKGSATSNWKKTPL CCCCCCCCCCEECCC	40.17	20068231
585	Sumoylation	SATSNWKKTPLSTGG CCCCCCEECCCCCCC	47.17	28112733
586	O-linked_Glycosylation	ATSNWKKTPLSTGGT CCCCCEECCCCCCCE	26.24	30059200
586	Phosphorylation	ATSNWKKTPLSTGGT CCCCCEECCCCCCCE	26.24	24732914
589	O-linked_Glycosylation	NWKKTPLSTGGTLAF CCEECCCCCCCEEEE	26.64	30059200
589	Phosphorylation	NWKKTPLSTGGTLAF CCEECCCCCCCEEEE	26.64	24732914
590	O-linked_Glycosylation	WKKTPLSTGGTLAFV CEECCCCCCCEEEEE	47.52	30059200
590	Phosphorylation	WKKTPLSTGGTLAFV CEECCCCCCCEEEEE	47.52	24732914
593	O-linked_Glycosylation	TPLSTGGTLAFVSPS CCCCCCCEEEEECHH	19.09	30059200
593	Phosphorylation	TPLSTGGTLAFVSPS CCCCCCCEEEEECHH	19.09	24732914
598	Phosphorylation	GGTLAFVSPSLAVHK CCEEEEECHHHCCCC	11.43	25159151
600	Phosphorylation	TLAFVSPSLAVHKSS EEEEECHHHCCCCCC	22.81	25159151
605	Sumoylation	SPSLAVHKSSSAVDR CHHHCCCCCCCCHHH	45.49	28112733
625	O-linked_Glycosylation	LDMIPPRSIPQSATW HHHCCCCCCCCCCCC	44.38	30059200
629	Phosphorylation	PPRSIPQSATWK--- CCCCCCCCCCCC---	23.47	24719451
633	Methylation	IPQSATWK------- CCCCCCCC-------	46.21	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of P66A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of P66A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of P66A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBBP4_HUMAN	RBBP4	physical	22939629
RBBP7_HUMAN	RBBP7	physical	22939629
K1C40_HUMAN	KRT40	physical	25416956
CHD3_HUMAN	CHD3	physical	26344197
MBD2_HUMAN	MBD2	physical	26344197
MBD3_HUMAN	MBD3	physical	26344197
MTA1_HUMAN	MTA1	physical	26344197
RUVB1_HUMAN	RUVBL1	physical	26344197
CHD5_HUMAN	CHD5	physical	28514442
HDAC1_HUMAN	HDAC1	physical	28514442
CHD3_HUMAN	CHD3	physical	28514442
PKCB1_HUMAN	ZMYND8	physical	28514442
ZN592_HUMAN	ZNF592	physical	28514442
MBD2_HUMAN	MBD2	physical	28514442
MTA3_HUMAN	MTA3	physical	28514442
ZN687_HUMAN	ZNF687	physical	28514442
CHD4_HUMAN	CHD4	physical	28514442
MBD3_HUMAN	MBD3	physical	28514442
MTA1_HUMAN	MTA1	physical	28514442
MTA2_HUMAN	MTA2	physical	28514442
CDKA1_HUMAN	CDK2AP1	physical	28514442
APBP2_HUMAN	APPBP2	physical	28514442
RBBP4_HUMAN	RBBP4	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of P66A_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-49; SER-100; SER-107;SER-114; THR-189 AND SER-340, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-100; SER-107; SER-114AND SER-340, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-49; SER-100; SER-107;SER-114; SER-340; SER-546; SER-548 AND SER-598, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-49; SER-100; SER-107;SER-113 AND SER-114, AND MASS SPECTROMETRY.	18220336 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-546 AND SER-598, ANDMASS SPECTROMETRY.	17924679 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-100; SER-107 ANDSER-114, AND MASS SPECTROMETRY.	16964243 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-189, AND MASSSPECTROMETRY.	18691976 [Abstract]