| UniProt ID | RETR3_HUMAN | |
|---|---|---|
| UniProt AC | Q86VR2 | |
| Protein Name | Reticulophagy regulator 3 | |
| Gene Name | RETREG3 {ECO:0000312|HGNC:HGNC:27258} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 466 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | Mediates NRF1-enhanced neurite outgrowth.. | |
| Protein Sequence | MAEAEGVPTTPGPASGSTFRGRRDVSGSWERDQQVEAAQRALVEVLGPYEPLLSRVQAALVWERPARSALWCLGLNAAFWFFALTSLRLVFLLAFGLMIIVCIDQWKNKIWPEIKVPRPDALDNESWGFVHPRLLSVPELCHHVAEVWVSGTIFIRNVLLFKKQNPGKFCLLSCGILTFLAVLGRYVPGLLLSYLMLVTVMMWPLAVYHRLWDRAYVRLKPALQRLDFSVRGYMMSKQRERQLRRRALHPERAMDNHSDSEEELAAFCPQLDDSTVARELAITDSEHSDAEVSCTDNGTFNLSRGQTPLTEGSEDLDGHSDPEESFARDLPDFPSINMDPAGLDDEDDTSIGMPSLMYRSPPGAEEPQAPPASRDEAALPELLLGALPVGSNLTSNLASLVSQGMIQLALSGASQPGPSGAPAQRATRGFLRSPSSDLDTDAEGDDFELLDQSELSQLDPASSRSH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAEAEGVPT ------CCCCCCCCC | 22814378 | ||
| 9 | Phosphorylation | AEAEGVPTTPGPASG CCCCCCCCCCCCCCC | 29255136 | ||
| 10 | Phosphorylation | EAEGVPTTPGPASGS CCCCCCCCCCCCCCC | 29255136 | ||
| 15 | Phosphorylation | PTTPGPASGSTFRGR CCCCCCCCCCCCCCC | 25159151 | ||
| 17 | Phosphorylation | TPGPASGSTFRGRRD CCCCCCCCCCCCCCC | 25867546 | ||
| 18 | Phosphorylation | PGPASGSTFRGRRDV CCCCCCCCCCCCCCC | 25159151 | ||
| 25 | Ubiquitination | TFRGRRDVSGSWERD CCCCCCCCCCCCHHH | - | ||
| 26 | Phosphorylation | FRGRRDVSGSWERDQ CCCCCCCCCCCHHHH | 23401153 | ||
| 28 | Phosphorylation | GRRDVSGSWERDQQV CCCCCCCCCHHHHHH | 21712546 | ||
| 49 | Phosphorylation | LVEVLGPYEPLLSRV HHHHHCCCHHHHHHH | 22817900 | ||
| 115 | Ubiquitination | NKIWPEIKVPRPDAL CCCCCCCCCCCCCCC | 21890473 | ||
| 115 | Ubiquitination | NKIWPEIKVPRPDAL CCCCCCCCCCCCCCC | 21890473 | ||
| 220 | Ubiquitination | DRAYVRLKPALQRLD HHHHHHHHHHHHHCC | - | ||
| 229 | Phosphorylation | ALQRLDFSVRGYMMS HHHHCCHHHHHHHCH | 23911959 | ||
| 233 | Phosphorylation | LDFSVRGYMMSKQRE CCHHHHHHHCHHHHH | 22798277 | ||
| 236 | Phosphorylation | SVRGYMMSKQRERQL HHHHHHCHHHHHHHH | 21712546 | ||
| 258 | Phosphorylation | ERAMDNHSDSEEELA HHHCCCCCCCHHHHH | 29255136 | ||
| 260 | Phosphorylation | AMDNHSDSEEELAAF HCCCCCCCHHHHHHH | 29255136 | ||
| 274 | Phosphorylation | FCPQLDDSTVARELA HCCCCCCHHHHHHHC | 23927012 | ||
| 275 | Phosphorylation | CPQLDDSTVARELAI CCCCCCHHHHHHHCC | 23927012 | ||
| 283 | Phosphorylation | VARELAITDSEHSDA HHHHHCCCCCCCCCC | 22617229 | ||
| 285 | Phosphorylation | RELAITDSEHSDAEV HHHCCCCCCCCCCEE | 22617229 | ||
| 288 | Phosphorylation | AITDSEHSDAEVSCT CCCCCCCCCCEEEEC | 22617229 | ||
| 293 | Phosphorylation | EHSDAEVSCTDNGTF CCCCCEEEECCCCCE | 30108239 | ||
| 295 | Phosphorylation | SDAEVSCTDNGTFNL CCCEEEECCCCCEEE | 23090842 | ||
| 299 | Phosphorylation | VSCTDNGTFNLSRGQ EEECCCCCEEECCCC | 30576142 | ||
| 303 | Phosphorylation | DNGTFNLSRGQTPLT CCCCEEECCCCCCCC | 23090842 | ||
| 307 | Phosphorylation | FNLSRGQTPLTEGSE EEECCCCCCCCCCCC | 29255136 | ||
| 310 | Phosphorylation | SRGQTPLTEGSEDLD CCCCCCCCCCCCCCC | 29255136 | ||
| 313 | Phosphorylation | QTPLTEGSEDLDGHS CCCCCCCCCCCCCCC | 29255136 | ||
| 320 | Phosphorylation | SEDLDGHSDPEESFA CCCCCCCCCHHHHHH | 29255136 | ||
| 325 | Phosphorylation | GHSDPEESFARDLPD CCCCHHHHHHHCCCC | 23927012 | ||
| 335 | Phosphorylation | RDLPDFPSINMDPAG HCCCCCCCCCCCCCC | 20068231 | ||
| 349 | Phosphorylation | GLDDEDDTSIGMPSL CCCCCCCCCCCCCCC | 26657352 | ||
| 350 | Phosphorylation | LDDEDDTSIGMPSLM CCCCCCCCCCCCCCC | 29507054 | ||
| 355 | Phosphorylation | DTSIGMPSLMYRSPP CCCCCCCCCCCCCCC | 28102081 | ||
| 358 | Phosphorylation | IGMPSLMYRSPPGAE CCCCCCCCCCCCCCC | - | ||
| 360 | Phosphorylation | MPSLMYRSPPGAEEP CCCCCCCCCCCCCCC | 30266825 | ||
| 373 | Phosphorylation | EPQAPPASRDEAALP CCCCCCCCCCHHHHH | 25849741 | ||
| 433 | Phosphorylation | ATRGFLRSPSSDLDT HHCCCCCCCCCCCCC | 26503892 | ||
| 435 | Phosphorylation | RGFLRSPSSDLDTDA CCCCCCCCCCCCCCC | 30278072 | ||
| 436 | Phosphorylation | GFLRSPSSDLDTDAE CCCCCCCCCCCCCCC | 30278072 | ||
| 440 | Phosphorylation | SPSSDLDTDAEGDDF CCCCCCCCCCCCCCC | 26503892 | ||
| 453 | Phosphorylation | DFELLDQSELSQLDP CCHHCCHHHHHHCCC | 28464451 | ||
| 456 | Phosphorylation | LLDQSELSQLDPASS HCCHHHHHHCCCCCC | 28450419 | ||
| 462 | Phosphorylation | LSQLDPASSRSH--- HHHCCCCCCCCC--- | 28634120 | ||
| 463 | Phosphorylation | SQLDPASSRSH---- HHCCCCCCCCC---- | 28634120 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RETR3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RETR3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RETR3_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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