GPHRA_HUMAN - dbPTM
GPHRA_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GPHRA_HUMAN
UniProt AC B7ZAQ6
Protein Name Golgi pH regulator A
Gene Name GPR89A
Organism Homo sapiens (Human).
Sequence Length 455
Subcellular Localization Golgi apparatus membrane
Multi-pass membrane protein.
Protein Description Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance..
Protein Sequence MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
135PhosphorylationGDPFPILSPKHGILS
CCCCCCCCCCCCCCC
32.4024719451
180N-linked_GlycosylationYMSYFLRNVTDTDIL
HHHHHHHCCCHHHHH
43.09UniProtKB CARBOHYD
182PhosphorylationSYFLRNVTDTDILAL
HHHHHCCCHHHHHHH
36.41-
203AcetylationTMDMIISKKKRMAMA
HHHHHHHHHHHHHHH
52.4811174259
203UbiquitinationTMDMIISKKKRMAMA
HHHHHHHHHHHHHHH
52.4821906983
204AcetylationMDMIISKKKRMAMAR
HHHHHHHHHHHHHHH
38.5311174269
204UbiquitinationMDMIISKKKRMAMAR
HHHHHHHHHHHHHHH
38.53-
217UbiquitinationARRTMFQKGEVHNKP
HHHHHHHHCCCCCCC
45.86-
223UbiquitinationQKGEVHNKPSGFWGM
HHCCCCCCCCCCCCC
26.19-
243N-linked_GlycosylationTSASGSENLTLIQQE
ECCCCCCCEEHHHHH
39.77UniProtKB CARBOHYD
272UbiquitinationTADLYATKERIEYSK
HHHHHHCHHHHHHCH
36.5021906983
279UbiquitinationKERIEYSKTFKGKYF
HHHHHHCHHHCCCCH
58.012190698
285PhosphorylationSKTFKGKYFNFLGYF
CHHHCCCCHHHHHHH
16.6625907765
291PhosphorylationKYFNFLGYFFSIYCV
CCHHHHHHHHHHHHH
12.0025907765
294PhosphorylationNFLGYFFSIYCVWKI
HHHHHHHHHHHHHHH
11.6225907765
296PhosphorylationLGYFFSIYCVWKIFM
HHHHHHHHHHHHHHH
4.6325907765

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GPHRA_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GPHRA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GPHRA_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of GPHRA_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GPHRA_HUMAN

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Related Literatures of Post-Translational Modification

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