REEP5_HUMAN - dbPTM
REEP5_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID REEP5_HUMAN
UniProt AC Q00765
Protein Name Receptor expression-enhancing protein 5
Gene Name REEP5
Organism Homo sapiens (Human).
Sequence Length 189
Subcellular Localization Membrane
Multi-pass membrane protein . Endoplasmic reticulum . Localizes to endoplasmic reticulum tubular network.
Protein Description May promote functional cell surface expression of olfactory receptors..
Protein Sequence MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSAAMRERF
------CCHHHHHHH		25.4119413330
16UbiquitinationFDRFLHEKNCMTDLL
HHHHHHHCCHHHHHH		44.7021890473
162-HydroxyisobutyrylationFDRFLHEKNCMTDLL
HHHHHHHCCHHHHHH		44.70-
16UbiquitinationFDRFLHEKNCMTDLL
HHHHHHHCCHHHHHH		44.7022817900
16MalonylationFDRFLHEKNCMTDLL
HHHHHHHCCHHHHHH		44.7026320211
252-HydroxyisobutyrylationCMTDLLAKLEAKTGV
HHHHHHHHHHHHHCC		46.99-
25UbiquitinationCMTDLLAKLEAKTGV
HHHHHHHHHHHHHCC		46.9929967540
29UbiquitinationLLAKLEAKTGVNRSF
HHHHHHHHHCCCHHH		36.1127667366
147UbiquitinationIIRPFFLKHESQMDS
HHHHHHHCCHHHHHH		39.9221890473
147UbiquitinationIIRPFFLKHESQMDS
HHHHHHHCCHHHHHH		39.9221963094
150PhosphorylationPFFLKHESQMDSVVK
HHHHCCHHHHHHHHH		30.4425159151
154PhosphorylationKHESQMDSVVKDLKD
CCHHHHHHHHHHHHH		24.3825159151
157UbiquitinationSQMDSVVKDLKDKAK
HHHHHHHHHHHHHHH		56.0121890473
157UbiquitinationSQMDSVVKDLKDKAK
HHHHHHHHHHHHHHH		56.0122817900
160UbiquitinationDSVVKDLKDKAKETA
HHHHHHHHHHHHHHH		68.2822817900
162AcetylationVVKDLKDKAKETADA
HHHHHHHHHHHHHHH		60.8219608861
1622-HydroxyisobutyrylationVVKDLKDKAKETADA
HHHHHHHHHHHHHHH		60.82-
162UbiquitinationVVKDLKDKAKETADA
HHHHHHHHHHHHHHH		60.8222817900
164AcetylationKDLKDKAKETADAIT
HHHHHHHHHHHHHHH		62.4319608861
164UbiquitinationKDLKDKAKETADAIT
HHHHHHHHHHHHHHH		62.4327667366
172UbiquitinationETADAITKEAKKATV
HHHHHHHHHHHHHHH		49.9527667366
175UbiquitinationDAITKEAKKATVNLL
HHHHHHHHHHHHHHC		43.9922817900
176UbiquitinationAITKEAKKATVNLLG
HHHHHHHHHHHHHCC		57.2327667366
178PhosphorylationTKEAKKATVNLLGEE
HHHHHHHHHHHCCCC		20.8527050516
186UbiquitinationVNLLGEEKKST----
HHHCCCCCCCC----		47.9627667366
186MalonylationVNLLGEEKKST----
HHHCCCCCCCC----		47.9632601280
188PhosphorylationLLGEEKKST------
HCCCCCCCC------		50.8723911959
189PhosphorylationLGEEKKST-------
CCCCCCCC-------		52.0523911959
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of REEP5_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of REEP5_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of REEP5_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ACSL3_HUMANACSL3physical
26496610
GALT2_HUMANGALNT2physical
26496610
SMCA4_HUMANSMARCA4physical
26496610
ZMYM3_HUMANZMYM3physical
26496610
MED17_HUMANMED17physical
26496610
SCAM2_HUMANSCAMP2physical
26496610
DNJC8_HUMANDNAJC8physical
26496610
KDM2A_HUMANKDM2Aphysical
26496610
CNOT1_HUMANCNOT1physical
26496610
VPP2_HUMANATP6V0A2physical
26496610
FABD_HUMANMCATphysical
26496610
BRD7_HUMANBRD7physical
26496610
DERL2_HUMANDERL2physical
26496610
GOT1B_HUMANGOLT1Bphysical
26496610
IMPCT_HUMANIMPACTphysical
26496610
DOCK6_HUMANDOCK6physical
26496610
MTHSD_HUMANMTHFSDphysical
26496610
PSRC1_HUMANPSRC1physical
26496610
USMG5_HUMANUSMG5physical
26496610
REEP6_HUMANREEP6physical
26496610
SCAM4_HUMANSCAMP4physical
26496610
DGKH_HUMANDGKHphysical
26496610
GDE1_HUMANGDE1physical
28514442
MFN2_HUMANMFN2physical
28514442
TMM68_HUMANTMEM68physical
28514442
F210B_HUMANFAM210Bphysical
28514442
REEP6_HUMANREEP6physical
28514442
GLT16_HUMANGALNT16physical
28514442
TMUB2_HUMANTMUB2physical
28514442
SOGA3_HUMANSOGA3physical
28514442
PLS1_HUMANPLSCR1physical
28514442
GALT7_HUMANGALNT7physical
28514442
NCAM1_HUMANNCAM1physical
28514442
CD032_HUMANC4orf32physical
28514442
RNFT1_HUMANRNFT1physical
28514442
PRAF1_HUMANRABAC1physical
28514442
SCAM1_HUMANSCAMP1physical
28514442
CJ035_HUMANC10orf35physical
28514442
PRAF2_HUMANPRAF2physical
28514442
AT1B3_HUMANATP1B3physical
28514442
MRP4_HUMANABCC4physical
28514442
KDSR_HUMANKDSRphysical
28514442
SCAM4_HUMANSCAMP4physical
28514442
IFN21_HUMANIFNA21physical
28514442
EBP_HUMANEBPphysical
28514442
RETR3_HUMANFAM134Cphysical
28514442
TMPPE_HUMANTMPPEphysical
28514442
GP107_HUMANGPR107physical
28514442
FAM3C_HUMANFAM3Cphysical
28514442
AKAP1_HUMANAKAP1physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of REEP5_HUMAN

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Related Literatures of Post-Translational Modification

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