dbPTM

GOT1B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GOT1B_HUMAN
UniProt AC	Q9Y3E0
Protein Name	Vesicle transport protein GOT1B
Gene Name	GOLT1B
Organism	Homo sapiens (Human).
Sequence Length	138
Subcellular Localization	Golgi apparatus membrane Multi-pass membrane protein .
Protein Description	May be involved in fusion of ER-derived transport vesicles with the Golgi complex..
Protein Sequence	MISLTDTQKIGMGLTGFGVFFLFFGMILFFDKALLAIGNVLFVAGLAFVIGLERTFRFFFQKHKMKATGFFLGGVFVVLIGWPLIGMIFEIYGFFLLFRGFFPVVVGFIRRVPVLGSLLNLPGIRSFVDKVGESNNMV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MISLTDTQ -------CCCCCCHH	4.19	22223895
62	Ubiquitination	TFRFFFQKHKMKATG HHHHHHHHHCCHHHC	39.78	22817900
64	Ubiquitination	RFFFQKHKMKATGFF HHHHHHHCCHHHCHH	49.48	22817900
66	Ubiquitination	FFQKHKMKATGFFLG HHHHHCCHHHCHHHC	47.83	22817900
130	Ubiquitination	GIRSFVDKVGESNNM CHHHHHHHHCCCCCC	47.00	21906983
137	Sulfoxidation	KVGESNNMV------ HHCCCCCCC------	4.41	21406390

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GOT1B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GOT1B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GOT1B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANXA1_HUMAN	ANXA1	physical	26496610
AT1A1_HUMAN	ATP1A1	physical	26496610
AT2A2_HUMAN	ATP2A2	physical	26496610
ATPA_HUMAN	ATP5A1	physical	26496610
ATPB_HUMAN	ATP5B	physical	26496610
ATP5J_HUMAN	ATP5J	physical	26496610
VATA_HUMAN	ATP6V1A	physical	26496610
VATB2_HUMAN	ATP6V1B2	physical	26496610
VATE1_HUMAN	ATP6V1E1	physical	26496610
VPP1_HUMAN	ATP6V0A1	physical	26496610
VAS1_HUMAN	ATP6AP1	physical	26496610
ATPO_HUMAN	ATP5O	physical	26496610
C1QBP_HUMAN	C1QBP	physical	26496610
CALU_HUMAN	CALU	physical	26496610
CAV1_HUMAN	CAV1	physical	26496610
CD59_HUMAN	CD59	physical	26496610
CD97_HUMAN	CD97	physical	26496610
CDC42_HUMAN	CDC42	physical	26496610
CLCN7_HUMAN	CLCN7	physical	26496610
COX41_HUMAN	COX4I1	physical	26496610
CBPM_HUMAN	CPM	physical	26496610
CY1_HUMAN	CYC1	physical	26496610
DSG2_HUMAN	DSG2	physical	26496610
STOM_HUMAN	STOM	physical	26496610
ETFB_HUMAN	ETFB	physical	26496610
EXTL2_HUMAN	EXTL2	physical	26496610
FLOT2_HUMAN	FLOT2	physical	26496610
GOGA2_HUMAN	GOLGA2	physical	26496610
PDIA3_HUMAN	PDIA3	physical	26496610
PLAK_HUMAN	JUP	physical	26496610
KTN1_HUMAN	KTN1	physical	26496610
LBR_HUMAN	LBR	physical	26496610
LEG1_HUMAN	LGALS1	physical	26496610
LIFR_HUMAN	LIFR	physical	26496610
M3K4_HUMAN	MAP3K4	physical	26496610
RAB8A_HUMAN	RAB8A	physical	26496610
MGST3_HUMAN	MGST3	physical	26496610
NDUA2_HUMAN	NDUFA2	physical	26496610
NDUA5_HUMAN	NDUFA5	physical	26496610
NDUA6_HUMAN	NDUFA6	physical	26496610
NDUA7_HUMAN	NDUFA7	physical	26496610
NDUA8_HUMAN	NDUFA8	physical	26496610
NDUA9_HUMAN	NDUFA9	physical	26496610
NDUAA_HUMAN	NDUFA10	physical	26496610
NDUB1_HUMAN	NDUFB1	physical	26496610
NDUB4_HUMAN	NDUFB4	physical	26496610
NDUB7_HUMAN	NDUFB7	physical	26496610
NDUB8_HUMAN	NDUFB8	physical	26496610
NDUS1_HUMAN	NDUFS1	physical	26496610
NDUS2_HUMAN	NDUFS2	physical	26496610
NDUS3_HUMAN	NDUFS3	physical	26496610
NDUV1_HUMAN	NDUFV1	physical	26496610
NDUS4_HUMAN	NDUFS4	physical	26496610
NDUS5_HUMAN	NDUFS5	physical	26496610
NDUS6_HUMAN	NDUFS6	physical	26496610
NDUS8_HUMAN	NDUFS8	physical	26496610
NDUV2_HUMAN	NDUFV2	physical	26496610
NDUV3_HUMAN	NDUFV3	physical	26496610
DDR2_HUMAN	DDR2	physical	26496610
PCDH7_HUMAN	PCDH7	physical	26496610
CHM1A_HUMAN	CHMP1A	physical	26496610
PHB_HUMAN	PHB	physical	26496610
KPB2_HUMAN	PHKA2	physical	26496610
HTRA1_HUMAN	HTRA1	physical	26496610
ABCD3_HUMAN	ABCD3	physical	26496610
P5CS_HUMAN	ALDH18A1	physical	26496610
RAB5C_HUMAN	RAB5C	physical	26496610
RECQ1_HUMAN	RECQL	physical	26496610
SNTB2_HUMAN	SNTB2	physical	26496610
SOAT1_HUMAN	SOAT1	physical	26496610
TFR1_HUMAN	TFRC	physical	26496610
TGFR1_HUMAN	TGFBR1	physical	26496610
TPIS_HUMAN	TPI1	physical	26496610
QCR1_HUMAN	UQCRC1	physical	26496610
QCR2_HUMAN	UQCRC2	physical	26496610
UCRI_HUMAN	UQCRFS1	physical	26496610
VDAC1_HUMAN	VDAC1	physical	26496610
VDAC2_HUMAN	VDAC2	physical	26496610
CXCR4_HUMAN	CXCR4	physical	26496610
RAI3_HUMAN	GPRC5A	physical	26496610
VA0D1_HUMAN	ATP6V0D1	physical	26496610
HGS_HUMAN	HGS	physical	26496610
XPR1_HUMAN	XPR1	physical	26496610
VAPB_HUMAN	VAPB	physical	26496610
VAPA_HUMAN	VAPA	physical	26496610
RB11B_HUMAN	RAB11B	physical	26496610
VATF_HUMAN	ATP6V1F	physical	26496610
COX5A_HUMAN	COX5A	physical	26496610
ABCG2_HUMAN	ABCG2	physical	26496610
PTGES_HUMAN	PTGES	physical	26496610
VATG1_HUMAN	ATP6V1G1	physical	26496610
SC22B_HUMAN	SEC22B	physical	26496610
MLEC_HUMAN	MLEC	physical	26496610
PIEZ1_HUMAN	PIEZO1	physical	26496610
SPCS2_HUMAN	SPCS2	physical	26496610
IST1_HUMAN	IST1	physical	26496610
PDC6I_HUMAN	PDCD6IP	physical	26496610
PDCD6_HUMAN	PDCD6	physical	26496610
BAP31_HUMAN	BCAP31	physical	26496610
FLOT1_HUMAN	FLOT1	physical	26496610
VPP3_HUMAN	TCIRG1	physical	26496610
HYOU1_HUMAN	HYOU1	physical	26496610
PRAF1_HUMAN	RABAC1	physical	26496610
ERLN1_HUMAN	ERLIN1	physical	26496610
CKAP4_HUMAN	CKAP4	physical	26496610
MIC60_HUMAN	IMMT	physical	26496610
ERLN2_HUMAN	ERLIN2	physical	26496610
PHB2_HUMAN	PHB2	physical	26496610
CHSS1_HUMAN	CHSY1	physical	26496610
ENDD1_HUMAN	ENDOD1	physical	26496610
SUN2_HUMAN	SUN2	physical	26496610
INT7_HUMAN	INTS7	physical	26496610
CHM2B_HUMAN	CHMP2B	physical	26496610
DRS7B_HUMAN	DHRS7B	physical	26496610
LRP10_HUMAN	LRP10	physical	26496610
MYOF_HUMAN	MYOF	physical	26496610
AT2C1_HUMAN	ATP2C1	physical	26496610
QCR8_HUMAN	UQCRQ	physical	26496610
GOLI4_HUMAN	GOLIM4	physical	26496610
ASTE1_HUMAN	ASTE1	physical	26496610
STML2_HUMAN	STOML2	physical	26496610
ITSN2_HUMAN	ITSN2	physical	26496610
NDUAD_HUMAN	NDUFA13	physical	26496610
VATD_HUMAN	ATP6V1D	physical	26496610
FA8A1_HUMAN	FAM8A1	physical	26496610
VATH_HUMAN	ATP6V1H	physical	26496610
SARAF_HUMAN	SARAF	physical	26496610
S38A2_HUMAN	SLC38A2	physical	26496610
CHPF2_HUMAN	CHPF2	physical	26496610
MIC19_HUMAN	CHCHD3	physical	26496610
DJC11_HUMAN	DNAJC11	physical	26496610
PLRKT_HUMAN	PLGRKT	physical	26496610
NDUAC_HUMAN	NDUFA12	physical	26496610
KDIS_HUMAN	KIDINS220	physical	26496610
NCK5L_HUMAN	NCKAP5L	physical	26496610
RM14_HUMAN	MRPL14	physical	26496610
TM237_HUMAN	TMEM237	physical	26496610
FUND2_HUMAN	FUNDC2	physical	26496610
VKOR1_HUMAN	VKORC1	physical	26496610
TM109_HUMAN	TMEM109	physical	26496610
MBOA7_HUMAN	MBOAT7	physical	26496610
TMM43_HUMAN	TMEM43	physical	26496610
CYBR1_HUMAN	CYBRD1	physical	26496610
REEP4_HUMAN	REEP4	physical	26496610
SGPP1_HUMAN	SGPP1	physical	26496610
YIPF5_HUMAN	YIPF5	physical	26496610
TMUB1_HUMAN	TMUB1	physical	26496610
MIC25_HUMAN	CHCHD6	physical	26496610
CC115_HUMAN	CCDC115	physical	26496610
MCU_HUMAN	MCU	physical	26496610
PP4P1_HUMAN	TMEM55B	physical	26496610
RN185_HUMAN	RNF185	physical	26496610
ACBD5_HUMAN	ACBD5	physical	26496610
MYADM_HUMAN	MYADM	physical	26496610
MMGT1_HUMAN	MMGT1	physical	26496610
CAVN3_HUMAN	PRKCDBP	physical	26496610
OSBL8_HUMAN	OSBPL8	physical	26496610
CHM4B_HUMAN	CHMP4B	physical	26496610
TM199_HUMAN	TMEM199	physical	26496610
CAVN1_HUMAN	PTRF	physical	26496610
RABL3_HUMAN	RABL3	physical	26496610
UBAC2_HUMAN	UBAC2	physical	26496610
SFT2B_HUMAN	SFT2D2	physical	26496610
CF120_HUMAN	C6orf120	physical	26496610
LNP_HUMAN	KIAA1715	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GOT1B_HUMAN

Related Literatures of Post-Translational Modification