dbPTM

MMGT1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MMGT1_HUMAN
UniProt AC	Q8N4V1
Protein Name	Membrane magnesium transporter 1
Gene Name	MMGT1
Organism	Homo sapiens (Human).
Sequence Length	131
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein . Golgi apparatus membrane Multi-pass membrane protein . Early endosome membrane Multi-pass membrane protein .
Protein Description	Mediates Mg(2+) transport..
Protein Sequence	MAPSLWKGLVGIGLFALAHAAFSAAQHRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTANSSNQDALSSNTSLKLRKLESLRR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Malonylation	MDATSELKNKTFDTL CCCCHHHCCCCHHHH	52.96	26320211
79	Acetylation	ATSELKNKTFDTLRN CCHHHCCCCHHHHHC	49.32	26051181
122 (in isoform 1)	Ubiquitination	-	46.11	21890473
187 (in isoform 2)	Ubiquitination	-		21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MMGT1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MMGT1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MMGT1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
OCAD2_HUMAN	OCIAD2	physical	22939629
ODP2_HUMAN	DLAT	physical	22939629
MPV17_HUMAN	MPV17	physical	22939629
NDUAC_HUMAN	NDUFA12	physical	22939629
NDUB8_HUMAN	NDUFB8	physical	22939629
MTX2_HUMAN	MTX2	physical	22939629
MRP2_HUMAN	ABCC2	physical	22939629
RM01_HUMAN	MRPL1	physical	22939629
TM9S2_HUMAN	TM9SF2	physical	22939629
EMC9_HUMAN	EMC9	physical	22119785
UBQL2_HUMAN	UBQLN2	physical	22119785
EMC8_HUMAN	EMC8	physical	22119785
EMC2_HUMAN	EMC2	physical	22119785
EMC3_HUMAN	EMC3	physical	22119785
EMC10_HUMAN	EMC10	physical	22119785
EMC6_HUMAN	EMC6	physical	22119785
EMC1_HUMAN	EMC1	physical	22119785
EMC7_HUMAN	EMC7	physical	22119785
EMC4_HUMAN	EMC4	physical	22119785
DSRAD_HUMAN	ADAR	physical	26496610
CAV1_HUMAN	CAV1	physical	26496610
COX41_HUMAN	COX4I1	physical	26496610
FLOT2_HUMAN	FLOT2	physical	26496610
GALT2_HUMAN	GALNT2	physical	26496610
ROA2_HUMAN	HNRNPA2B1	physical	26496610
IMDH1_HUMAN	IMPDH1	physical	26496610
IMDH2_HUMAN	IMPDH2	physical	26496610
KTN1_HUMAN	KTN1	physical	26496610
DNLI3_HUMAN	LIG3	physical	26496610
MFAP1_HUMAN	MFAP1	physical	26496610
NDUA2_HUMAN	NDUFA2	physical	26496610
NDUA7_HUMAN	NDUFA7	physical	26496610
NDUB7_HUMAN	NDUFB7	physical	26496610
NDUS1_HUMAN	NDUFS1	physical	26496610
NDUS6_HUMAN	NDUFS6	physical	26496610
NDUV2_HUMAN	NDUFV2	physical	26496610
PHB_HUMAN	PHB	physical	26496610
DPOLB_HUMAN	POLB	physical	26496610
P52K_HUMAN	PRKRIR	physical	26496610
RS11_HUMAN	RPS11	physical	26496610
QCR1_HUMAN	UQCRC1	physical	26496610
VDAC1_HUMAN	VDAC1	physical	26496610
VDAC2_HUMAN	VDAC2	physical	26496610
DEK_HUMAN	DEK	physical	26496610
RBM10_HUMAN	RBM10	physical	26496610
RIOK3_HUMAN	RIOK3	physical	26496610
EMC2_HUMAN	EMC2	physical	26496610
MED24_HUMAN	MED24	physical	26496610
RBM6_HUMAN	RBM6	physical	26496610
RBM5_HUMAN	RBM5	physical	26496610
FLOT1_HUMAN	FLOT1	physical	26496610
EMC8_HUMAN	EMC8	physical	26496610
KIF1C_HUMAN	KIF1C	physical	26496610
CIKS_HUMAN	TRAF3IP2	physical	26496610
PLPL6_HUMAN	PNPLA6	physical	26496610
CKAP4_HUMAN	CKAP4	physical	26496610
MIC60_HUMAN	IMMT	physical	26496610
PHB2_HUMAN	PHB2	physical	26496610
DNJC8_HUMAN	DNAJC8	physical	26496610
SCAF8_HUMAN	SCAF8	physical	26496610
EMC1_HUMAN	EMC1	physical	26496610
SF3B1_HUMAN	SF3B1	physical	26496610
BRD4_HUMAN	BRD4	physical	26496610
OSBL3_HUMAN	OSBPL3	physical	26496610
GOLI4_HUMAN	GOLIM4	physical	26496610
FABD_HUMAN	MCAT	physical	26496610
NOP53_HUMAN	GLTSCR2	physical	26496610
STML2_HUMAN	STOML2	physical	26496610
EMC4_HUMAN	EMC4	physical	26496610
GOLM1_HUMAN	GOLM1	physical	26496610
BRWD1_HUMAN	BRWD1	physical	26496610
ANLN_HUMAN	ANLN	physical	26496610
RC3H2_HUMAN	RC3H2	physical	26496610
MIC19_HUMAN	CHCHD3	physical	26496610
CCAR1_HUMAN	CCAR1	physical	26496610
EMC3_HUMAN	EMC3	physical	26496610
DMAP1_HUMAN	DMAP1	physical	26496610
NDUAC_HUMAN	NDUFA12	physical	26496610
CT024_HUMAN	C20orf24	physical	26496610
PARD3_HUMAN	PARD3	physical	26496610
EMC7_HUMAN	EMC7	physical	26496610
PCNP_HUMAN	PCNP	physical	26496610
K1143_HUMAN	KIAA1143	physical	26496610
K1522_HUMAN	KIAA1522	physical	26496610
ZMAT3_HUMAN	ZMAT3	physical	26496610
TTC31_HUMAN	TTC31	physical	26496610
CS043_HUMAN	C19orf43	physical	26496610
TM109_HUMAN	TMEM109	physical	26496610
DERL1_HUMAN	DERL1	physical	26496610
TMM43_HUMAN	TMEM43	physical	26496610
CORO7_HUMAN	CORO7	physical	26496610
NSRP1_HUMAN	NSRP1	physical	26496610
MIC25_HUMAN	CHCHD6	physical	26496610
HDGR2_HUMAN	HDGFRP2	physical	26496610
SPF45_HUMAN	RBM17	physical	26496610
PPIL4_HUMAN	PPIL4	physical	26496610
PP4P1_HUMAN	TMEM55B	physical	26496610
ACBD5_HUMAN	ACBD5	physical	26496610
CAVN3_HUMAN	PRKCDBP	physical	26496610
CC124_HUMAN	CCDC124	physical	26496610
CE024_HUMAN	C5orf24	physical	26496610
TTC9C_HUMAN	TTC9C	physical	26496610
CAVN1_HUMAN	PTRF	physical	26496610
EMC10_HUMAN	EMC10	physical	26496610
CT451_HUMAN	CT45A1	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MMGT1_HUMAN

Related Literatures of Post-Translational Modification