TTC31_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC31_HUMAN
• UniProt AC: Q49AM3
• Protein Name: Tetratricopeptide repeat protein 31
• Gene Name: TTC31
• Organism: Homo sapiens (Human).
• Sequence Length: 519
• Protein Sequence: MAPIPKTVGRIKLDCSLRPSCPLEVAAAPKLCKEFGPEDYGEEDIVDFLRRLVESDPQGLHRIHVDGSSGRLQLWHHDYLLGHLDDEGKSTGQSDRGKGAEGLGTYCGLRKSFLYPPQESEPCPQSPSASATFPSVSDSLLQVAMPQKLLVTEEEANRLAEELVAEEERMKQKAEKKRLKKKRQKERKRQERLEQYCGEPKASTTSDGDESPPSSPGNPVQGQCGEEEDSLDLSSTFVSLALRKVGDWPLSARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKVQASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRSCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRCPRSTALRSPGLSPLLHYPSCHRSHPNQPLSQTQSRRPHPLKPQDPSKGWDILGLGLQHLSQAR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Ubiquitination	--MAPIPKTVGRIKL --CCCCCCCCCEEEE	57.47	29967540
7	Phosphorylation	-MAPIPKTVGRIKLD -CCCCCCCCCEEEEE	23.88	-
12	Ubiquitination	PKTVGRIKLDCSLRP CCCCCEEEEECCCCC	36.59	29967540
30	Ubiquitination	LEVAAAPKLCKEFGP HHHHHHHHHHHHHCC	62.89	29967540
98	Ubiquitination	TGQSDRGKGAEGLGT CCCCCCCCCCCCCCC	56.70	29967540
126	Phosphorylation	ESEPCPQSPSASATF CCCCCCCCCCCCCCC	13.13	28348404
128	Phosphorylation	EPCPQSPSASATFPS CCCCCCCCCCCCCCC	39.85	28348404
130	Phosphorylation	CPQSPSASATFPSVS CCCCCCCCCCCCCCC	31.98	28348404
132	Phosphorylation	QSPSASATFPSVSDS CCCCCCCCCCCCCHH	33.32	28348404
135	Phosphorylation	SASATFPSVSDSLLQ CCCCCCCCCCHHHHH	30.02	28348404
137	Phosphorylation	SATFPSVSDSLLQVA CCCCCCCCHHHHHHH	26.31	28348404
139	Phosphorylation	TFPSVSDSLLQVAMP CCCCCCHHHHHHHCC	24.39	28348404
171	Acetylation	VAEEERMKQKAEKKR HHHHHHHHHHHHHHH	55.67	12655589
244	Ubiquitination	FVSLALRKVGDWPLS HHHHHHHHHCCCCCH	51.96	-
256	Ubiquitination	PLSARREKGLNQEPQ CCHHHHHCCCCCCCC	67.87	29967540
265	Methylation	LNQEPQGRGLALQKM CCCCCCCHHHHHHHC	31.53	115919089
271	Ubiquitination	GRGLALQKMGQEEES CHHHHHHHCCCCCCC	45.94	29967540
278	Phosphorylation	KMGQEEESPPREERP HCCCCCCCCCCCCCC	43.41	29255136
288	Phosphorylation	REERPQQSPKVQASP CCCCCCCCCCCCCCH	22.80	29255136
290	Ubiquitination	ERPQQSPKVQASPGL CCCCCCCCCCCCHHH	52.83	29967540
294	Phosphorylation	QSPKVQASPGLLAAA CCCCCCCCHHHHHHH	11.47	27050516
381	Ubiquitination	RGLFRLGKALMGLQR HHHHHHHHHHHHHHH	42.83	-
404	Phosphorylation	QETLRGGSQPDAARE HHHHCCCCCCHHHHH	41.17	22210691
414	Phosphorylation	DAARELRSCLLHLTL HHHHHHHHHHHHHHH	23.03	22210691
434	Phosphorylation	GICAPPLSPGALQPL CCCCCCCCCCCCCCC	27.36	26657352
453	Phosphorylation	LAPSGLPSLRCPRST CCCCCCCCCCCCCCH	33.22	24719451
464	Phosphorylation	PRSTALRSPGLSPLL CCCHHCCCCCCCHHC	24.95	20873877
468	Phosphorylation	ALRSPGLSPLLHYPS HCCCCCCCHHCCCCC	21.29	20873877
475	Phosphorylation	SPLLHYPSCHRSHPN CHHCCCCCCCCCCCC	18.52	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC31_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC31_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC31_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TTC31_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.