MYOF_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYOF_HUMAN
• UniProt AC: Q9NZM1
• Protein Name: Myoferlin
• Gene Name: MYOF
• Organism: Homo sapiens (Human).
• Sequence Length: 2061
• Subcellular Localization: Cell membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein. Cytoplasmic vesicle membrane; Single-pass type II membrane protein. Concentrated at the membrane sites of both myoblast-myoblast and myoblast
• Protein Description: Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity)..
• Protein Sequence: MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDLVIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGKDGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKPNV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6 (in isoform 8)	Phosphorylation	-	4.32	30266825
8	Phosphorylation	MLRVIVESASNIPKT CCEEEEECCCCCCCC	26.55	21712546
10	Phosphorylation	RVIVESASNIPKTKF EEEEECCCCCCCCCC	44.57	21712546
11 (in isoform 8)	Phosphorylation	-	55.06	30622161
14	Malonylation	ESASNIPKTKFGKPD ECCCCCCCCCCCCCC	61.62	26320211
14	Ubiquitination	ESASNIPKTKFGKPD ECCCCCCCCCCCCCC	61.62	33845483
16	Acetylation	ASNIPKTKFGKPDPI CCCCCCCCCCCCCCE	59.24	26051181
33 (in isoform 2)	Phosphorylation	-	64.72	24043423
40 (in isoform 2)	Phosphorylation	-	59.65	24043423
42 (in isoform 2)	Phosphorylation	-	12.61	24043423
53	Ubiquitination	WNEILEFDLRGIPLD HHHHHHEECCCCCCC	26.53	27667366
60 (in isoform 2)	Ubiquitination	-	35.71	21890473
84	Ubiquitination	QNKLIGTATVALKDL CCCCEEEEEEEEHHC	8.55	23000965
84 (in isoform 8)	Ubiquitination	-	8.55	21890473
89	Ubiquitination	GTATVALKDLTGDQS EEEEEEEHHCCCCCC	40.74	29967540
98	Phosphorylation	LTGDQSRSLPYKLIS CCCCCCCCCCHHHHH	38.65	24719451
101	Phosphorylation	DQSRSLPYKLISLLN CCCCCCCHHHHHHHH	24.58	24719451
102	Ubiquitination	QSRSLPYKLISLLNE CCCCCCHHHHHHHHH	37.09	23000965
102 (in isoform 1)	Ubiquitination	-	37.09	21890473
102 (in isoform 3)	Ubiquitination	-	37.09	21890473
102 (in isoform 4)	Ubiquitination	-	37.09	21890473
102 (in isoform 5)	Ubiquitination	-	37.09	21890473
102 (in isoform 6)	Ubiquitination	-	37.09	21890473
102 (in isoform 7)	Ubiquitination	-	37.09	21890473
105	Phosphorylation	SLPYKLISLLNEKGQ CCCHHHHHHHHHCCC	36.92	24719451
125 (in isoform 2)	Ubiquitination	-	43.34	21890473
149 (in isoform 8)	Ubiquitination	-	67.88	21890473
167	Malonylation	AVRGPGPKGPVGTVS CCCCCCCCCCCCCCC	80.09	26320211
167	Ubiquitination	AVRGPGPKGPVGTVS CCCCCCCCCCCCCCC	80.09	33845483
167 (in isoform 1)	Ubiquitination	-	80.09	21890473
167 (in isoform 3)	Ubiquitination	-	80.09	21890473
167 (in isoform 5)	Ubiquitination	-	80.09	21890473
167 (in isoform 6)	Ubiquitination	-	80.09	21890473
167 (in isoform 7)	Ubiquitination	-	80.09	21890473
172	Phosphorylation	GPKGPVGTVSEAQLA CCCCCCCCCCHHHHH	22.54	30266825
174	Phosphorylation	KGPVGTVSEAQLARR CCCCCCCCHHHHHHH	27.35	19664994
177	Ubiquitination	VGTVSEAQLARRLTK CCCCCHHHHHHHHHH	31.44	27667366
183	Phosphorylation	AQLARRLTKVKNSRR HHHHHHHHHHHHHHH	31.79	25056879
188	Phosphorylation	RLTKVKNSRRMLSNK HHHHHHHHHHHHCCC	18.62	30622161
193	Phosphorylation	KNSRRMLSNKPQDFQ HHHHHHHCCCCCCCE	33.20	20068231
195	Ubiquitination	SRRMLSNKPQDFQIR HHHHHCCCCCCCEEE	40.45	33845483
212	Phosphorylation	VIEGRQLSGNNIRPV EEECCCCCCCCCCCE	31.01	28355574
264	Ubiquitination	MDEIISIRVYNSHSL HHHHHEEEEECCCCC	20.34	23503661
265	Ubiquitination	DEIISIRVYNSHSLR HHHHEEEEECCCCCC	5.17	23503661
266	Phosphorylation	EIISIRVYNSHSLRA HHHEEEEECCCCCCC	10.91	28152594
288	Phosphorylation	KIDVGFVYDEPGHAV EEEEEEEECCCCCCE	16.60	-
298	Ubiquitination	PGHAVMRKWLLLNDP CCCCEEEEEEECCCC	24.89	29967540
308	Phosphorylation	LLNDPEDTSSGSKGY ECCCCCCCCCCCCCC	24.11	27732954
309	Phosphorylation	LNDPEDTSSGSKGYM CCCCCCCCCCCCCCE	45.05	27732954
310	Phosphorylation	NDPEDTSSGSKGYMK CCCCCCCCCCCCCEE	49.53	27732954
312	Phosphorylation	PEDTSSGSKGYMKVS CCCCCCCCCCCEEEE	25.51	27732954
325	Phosphorylation	VSMFVLGTGDEPPPE EEEEEEECCCCCCCC	36.98	-
340	Phosphorylation	RRDRDNDSDDVESNL CCCCCCCCCCHHHHC	41.80	30266825
345	Phosphorylation	NDSDDVESNLLLPAG CCCCCHHHHCHHCHH	32.40	22199227
359	Phosphorylation	GIALRWVTFLLKIYR HHHHHHHHHHHHHHC	11.12	27174698
364 (in isoform 2)	Ubiquitination	-	2.58	-
365	Phosphorylation	VTFLLKIYRAEDIPQ HHHHHHHHCHHHCCC	11.37	27174698
382	Ubiquitination	DAFSQTVKEIFGGNA HHHHHHHHHHHCCCC	48.78	29967540
385	Ubiquitination	SQTVKEIFGGNADKK HHHHHHHHCCCCCCC	12.28	23503661
388	Ubiquitination	VKEIFGGNADKKNLV HHHHHCCCCCCCCCC	45.40	23503661
389	Ubiquitination	KEIFGGNADKKNLVD HHHHCCCCCCCCCCC	33.02	23503661
391	2-Hydroxyisobutyrylation	IFGGNADKKNLVDPF HHCCCCCCCCCCCCC	40.94	-
391	Ubiquitination	IFGGNADKKNLVDPF HHCCCCCCCCCCCCC	40.94	33845483
392	Ubiquitination	FGGNADKKNLVDPFV HCCCCCCCCCCCCCE	56.94	29967540
405	Ubiquitination	FVEVSFAGKKVCTNI CEEEEECCHHHHHHH	28.45	23503661
406	2-Hydroxyisobutyrylation	VEVSFAGKKVCTNII EEEEECCHHHHHHHH	38.31	-
406	Acetylation	VEVSFAGKKVCTNII EEEEECCHHHHHHHH	38.31	26051181
406	Ubiquitination	VEVSFAGKKVCTNII EEEEECCHHHHHHHH	38.31	23503661
407	Acetylation	EVSFAGKKVCTNIIE EEEECCHHHHHHHHH	41.44	30590627
407	Malonylation	EVSFAGKKVCTNIIE EEEECCHHHHHHHHH	41.44	26320211
407	Ubiquitination	EVSFAGKKVCTNIIE EEEECCHHHHHHHHH	41.44	23503661
410	Ubiquitination	FAGKKVCTNIIEKNA ECCHHHHHHHHHHCC	32.23	23503661
411	Ubiquitination	AGKKVCTNIIEKNAN CCHHHHHHHHHHCCC	28.28	23503661
425	Ubiquitination	NPEWNQVVNLQIKFP CCCHHHEEEEEEECH	4.22	23503661
431	Ubiquitination	VVNLQIKFPSVCEKI EEEEEEECHHHHHEE	6.11	23503661
437	2-Hydroxyisobutyrylation	KFPSVCEKIKLTIYD ECHHHHHEEEEEEEE	39.76	-
439	Ubiquitination	PSVCEKIKLTIYDWD HHHHHEEEEEEEEHH	51.12	29967540
450	Ubiquitination	YDWDRLTKNDVVGTT EEHHHCCCCCCCCCE	56.60	33845483
456	Phosphorylation	TKNDVVGTTYLHLSK CCCCCCCCEEEEHHH	10.72	28152594
457	Phosphorylation	KNDVVGTTYLHLSKI CCCCCCCEEEEHHHH	20.39	28152594
458	Phosphorylation	NDVVGTTYLHLSKIA CCCCCCEEEEHHHHH	7.61	28152594
462	Phosphorylation	GTTYLHLSKIAASGG CCEEEEHHHHHHCCC	15.98	28152594
485 (in isoform 2)	Ubiquitination	-	12.56	21890473
505 (in isoform 2)	Ubiquitination	-	12.54	-
509	Ubiquitination	CYLNLYGSPREYTGF EEEECCCCCCCCCCC	13.76	23503661
513	Phosphorylation	LYGSPREYTGFPDPY CCCCCCCCCCCCCCC	17.28	-
514	Phosphorylation	YGSPREYTGFPDPYD CCCCCCCCCCCCCCC	27.82	-
514	Ubiquitination	YGSPREYTGFPDPYD CCCCCCCCCCCCCCC	27.82	23503661
514 (in isoform 6)	Ubiquitination	-	27.82	21890473
520	Phosphorylation	YTGFPDPYDELNTGK CCCCCCCCCCCCCCC	29.45	-
525 (in isoform 2)	Ubiquitination	-	53.55	-
527	Ubiquitination	YDELNTGKGEGVAYR CCCCCCCCCCCCHHH	52.31	21906983
527 (in isoform 1)	Ubiquitination	-	52.31	21890473
527 (in isoform 3)	Ubiquitination	-	52.31	21890473
527 (in isoform 5)	Ubiquitination	-	52.31	21890473
529	Ubiquitination	ELNTGKGEGVAYRGR CCCCCCCCCCHHHHH	54.72	23503661
534	Ubiquitination	KGEGVAYRGRILVEL CCCCCHHHHHHHHHH	20.41	23503661
535	Ubiquitination	GEGVAYRGRILVELA CCCCHHHHHHHHHHH	14.33	23503661
539	Ubiquitination	AYRGRILVELATFLE HHHHHHHHHHHHHHH	5.43	23503661
540	Ubiquitination	YRGRILVELATFLEK HHHHHHHHHHHHHHH	29.28	23503661
547	Ubiquitination	ELATFLEKTPPDKKL HHHHHHHHCCCCCCC	69.36	23503661
548	Phosphorylation	LATFLEKTPPDKKLE HHHHHHHCCCCCCCC	30.58	22199227
549	Ubiquitination	ATFLEKTPPDKKLEP HHHHHHCCCCCCCCC	46.27	23503661
552	Ubiquitination	LEKTPPDKKLEPISN HHHCCCCCCCCCCCC	66.10	23503661
553	Acetylation	EKTPPDKKLEPISND HHCCCCCCCCCCCCC	66.52	-
553	Malonylation	EKTPPDKKLEPISND HHCCCCCCCCCCCCC	66.52	26320211
553	Ubiquitination	EKTPPDKKLEPISND HHCCCCCCCCCCCCC	66.52	23503661
554	Ubiquitination	KTPPDKKLEPISNDD HCCCCCCCCCCCCCC	13.42	29901268
555	Ubiquitination	TPPDKKLEPISNDDL CCCCCCCCCCCCCCE	49.85	23503661
558	Phosphorylation	DKKLEPISNDDLLVV CCCCCCCCCCCEEEE	44.94	29514088
560	Ubiquitination	KLEPISNDDLLVVEK CCCCCCCCCEEEEHH	40.94	23503661
567	Acetylation	DDLLVVEKYQRRRKY CCEEEEHHHHHHHCC	34.76	26051181
567	Ubiquitination	DDLLVVEKYQRRRKY CCEEEEHHHHHHHCC	34.76	29901268
570	Ubiquitination	LVVEKYQRRRKYSLS EEEHHHHHHHCCCHH	36.96	23503661
573	Ubiquitination	EKYQRRRKYSLSAVF HHHHHHHCCCHHHHH	37.06	23503661
598	Ubiquitination	EAIQFEVSIGNYGNK HHHEEEEECCCCCCC	19.99	29901268
608	Phosphorylation	NYGNKFDTTCKPLAS CCCCCCCCCCCCCCC	36.91	26846344
609	Phosphorylation	YGNKFDTTCKPLAST CCCCCCCCCCCCCCC	22.00	26846344
611	Ubiquitination	NKFDTTCKPLASTTQ CCCCCCCCCCCCCCC	40.76	29901268
615	Phosphorylation	TTCKPLASTTQYSRA CCCCCCCCCCCCEEE	39.40	26846344
616	Phosphorylation	TCKPLASTTQYSRAV CCCCCCCCCCCEEEE	16.59	26846344
617	Phosphorylation	CKPLASTTQYSRAVF CCCCCCCCCCEEEEE	24.02	26846344
619	Phosphorylation	PLASTTQYSRAVFDG CCCCCCCCEEEEECC	9.68	26846344
620	Phosphorylation	LASTTQYSRAVFDGN CCCCCCCEEEEECCC	12.16	26846344
637	Phosphorylation	YYLPWAHTKPVVTLT EEECCCCCCCEEEEE	29.33	20058876
642	Phosphorylation	AHTKPVVTLTSYWED CCCCCEEEEEHHHHH	25.26	20058876
670 (in isoform 2)	Ubiquitination	-	19.69	-
675	2-Hydroxyisobutyrylation	QTNIEALKSGIQGKI HHHHHHHHHHCCCCC	54.40	-
675	Acetylation	QTNIEALKSGIQGKI HHHHHHHHHHCCCCC	54.40	26051181
682	Ubiquitination	KSGIQGKIPANQLAE HHHCCCCCCHHHHHH	5.08	27667366
694	Ubiquitination	LAELWLKLIDEVIED HHHHHHHHHHHHHHH	5.82	23503661
699	Ubiquitination	LKLIDEVIEDTRYTL HHHHHHHHHHCCCEE	3.59	29901268
712	2-Hydroxyisobutyrylation	TLPLTEGKANVTVLD EEECCCCCCCEEEEH	30.47	-
712	Ubiquitination	TLPLTEGKANVTVLD EEECCCCCCCEEEEH	30.47	29901268
720	Phosphorylation	ANVTVLDTQIRKLRS CCEEEEHHHHHHHHH	23.02	28851738
727	Phosphorylation	TQIRKLRSRSLSQIH HHHHHHHHCCHHHHH	36.34	23927012
729	Phosphorylation	IRKLRSRSLSQIHEA HHHHHHCCHHHHHHH	33.35	29255136
731	Phosphorylation	KLRSRSLSQIHEAAV HHHHCCHHHHHHHHH	28.47	29255136
795	Ubiquitination	YARIPAHQVLYSTSG EEEECHHHEEECCCC	29.08	33845483
798	Phosphorylation	IPAHQVLYSTSGENA ECHHHEEECCCCCCC	15.85	28152594
799	Phosphorylation	PAHQVLYSTSGENAS CHHHEEECCCCCCCC	16.37	28152594
799	Ubiquitination	PAHQVLYSTSGENAS CHHHEEECCCCCCCC	16.37	33845483
800	Phosphorylation	AHQVLYSTSGENASG HHHEEECCCCCCCCC	27.48	28152594
801	Phosphorylation	HQVLYSTSGENASGK HHEEECCCCCCCCCC	37.86	28152594
805	Ubiquitination	YSTSGENASGKYCGK ECCCCCCCCCCCCCC	18.50	23503661
806	Ubiquitination	STSGENASGKYCGKT CCCCCCCCCCCCCCE	47.61	27667366
808	2-Hydroxyisobutyrylation	SGENASGKYCGKTQT CCCCCCCCCCCCEEE	34.57	-
808	Acetylation	SGENASGKYCGKTQT CCCCCCCCCCCCEEE	34.57	26051181
808	Ubiquitination	SGENASGKYCGKTQT CCCCCCCCCCCCEEE	34.57	33845483
811	Ubiquitination	NASGKYCGKTQTIFL CCCCCCCCCEEEEEE	32.72	27667366
812	Ubiquitination	ASGKYCGKTQTIFLK CCCCCCCCEEEEEEE	33.62	33845483
824	2-Hydroxyisobutyrylation	FLKYPQEKNNGPKVP EEECCHHHCCCCCCC	50.93	-
824	Ubiquitination	FLKYPQEKNNGPKVP EEECCHHHCCCCCCC	50.93	27667366
847	2-Hydroxyisobutyrylation	LGLSAVEKKFNSFAE EECHHHHHHHHHHCC	56.94	-
847	Acetylation	LGLSAVEKKFNSFAE EECHHHHHHHHHHCC	56.94	66727007
864	Phosphorylation	FTVFAEMYENQALMF EEEEEEEHHCCEECC	11.84	30576142
871	Acetylation	YENQALMFGKWGTSG HHCCEECCCCCCCCC	10.67	19608861
871	Ubiquitination	YENQALMFGKWGTSG HHCCEECCCCCCCCC	10.67	29967540
876	Phosphorylation	LMFGKWGTSGLVGRH ECCCCCCCCCCCCCC	20.64	22199227
877	Phosphorylation	MFGKWGTSGLVGRHK CCCCCCCCCCCCCCC	26.62	22199227
878	Ubiquitination	FGKWGTSGLVGRHKF CCCCCCCCCCCCCCC	24.99	29901268
884	2-Hydroxyisobutyrylation	SGLVGRHKFSDVTGK CCCCCCCCCCCCCCC	45.24	-
884	Acetylation	SGLVGRHKFSDVTGK CCCCCCCCCCCCCCC	45.24	19608861
884	Malonylation	SGLVGRHKFSDVTGK CCCCCCCCCCCCCCC	45.24	32601280
884	Ubiquitination	SGLVGRHKFSDVTGK CCCCCCCCCCCCCCC	45.24	19608861
891	Ubiquitination	KFSDVTGKIKLKREF CCCCCCCCEEEEEEE	27.57	29901268
905 (in isoform 2)	Ubiquitination	-	17.41	-
918	Phosphorylation	WIVDPERSLLTEADA EEECCCCCCCCHHCC	26.52	23663014
921	Phosphorylation	DPERSLLTEADAGHT CCCCCCCCHHCCCCC	34.13	23663014
928	Phosphorylation	TEADAGHTEFTDEVY CHHCCCCCCCCHHHH	31.69	23663014
929	Ubiquitination	EADAGHTEFTDEVYQ HHCCCCCCCCHHHHC	40.66	23503661
931	Phosphorylation	DAGHTEFTDEVYQNE CCCCCCCCHHHHCCC	25.64	-
934	Ubiquitination	HTEFTDEVYQNESRY CCCCCHHHHCCCCCC	7.11	23503661
935	Phosphorylation	TEFTDEVYQNESRYP CCCCHHHHCCCCCCC	11.99	-
947	Ubiquitination	RYPGGDWKPAEDTYT CCCCCCCCCCCCCCC	38.81	23503661
953	Phosphorylation	WKPAEDTYTDANGDK CCCCCCCCCCCCCCC	18.23	-
963	Phosphorylation	ANGDKAASPSELTCP CCCCCCCCHHHCCCC	33.54	28348404
965	Phosphorylation	GDKAASPSELTCPPG CCCCCCHHHCCCCCC	42.62	28348404
967	Ubiquitination	KAASPSELTCPPGWE CCCCHHHCCCCCCCC	7.58	21963094
968	Phosphorylation	AASPSELTCPPGWEW CCCHHHCCCCCCCCC	20.93	28102081
971	Ubiquitination	PSELTCPPGWEWEDD HHHCCCCCCCCCCCC	63.78	23503661
973	Ubiquitination	ELTCPPGWEWEDDAW HCCCCCCCCCCCCCE	17.19	23503661
978	Ubiquitination	PGWEWEDDAWSYDIN CCCCCCCCCEEEECC	38.12	33845483
991	Malonylation	INRAVDEKGWEYGIT CCHHHHCCCCCCCCC	65.93	26320211
991	Ubiquitination	INRAVDEKGWEYGIT CCHHHHCCCCCCCCC	65.93	33845483
1013	2-Hydroxyisobutyrylation	KSWVAAEKMYHTHRR CCHHHHHHHHHHHHH	39.78	-
1015	Phosphorylation	WVAAEKMYHTHRRRR HHHHHHHHHHHHHHH	18.03	28152594
1015	Ubiquitination	WVAAEKMYHTHRRRR HHHHHHHHHHHHHHH	18.03	29967540
1016	Ubiquitination	VAAEKMYHTHRRRRL HHHHHHHHHHHHHHH	16.23	29967540
1017	Phosphorylation	AAEKMYHTHRRRRLV HHHHHHHHHHHHHHH	10.29	28152594
1028	Ubiquitination	RRLVRKRKKDLTQTA HHHHHHHHHHHHHHH	54.39	29967540
1029	Ubiquitination	RLVRKRKKDLTQTAS HHHHHHHHHHHHHHH	63.10	29967540
1032	Phosphorylation	RKRKKDLTQTASSTA HHHHHHHHHHHHHHH	33.73	23403867
1034	Phosphorylation	RKKDLTQTASSTARA HHHHHHHHHHHHHHH	24.22	23403867
1036	Phosphorylation	KDLTQTASSTARAME HHHHHHHHHHHHHHH	31.44	25849741
1037	Phosphorylation	DLTQTASSTARAMEE HHHHHHHHHHHHHHH	24.50	23403867
1038	Phosphorylation	LTQTASSTARAMEEL HHHHHHHHHHHHHHH	20.05	23403867
1064	Methylation	IGWKFHWKQRSSDTF HCCEEECCCCCCHHH	27.54	115973559
1066	Ubiquitination	WKFHWKQRSSDTFRR CEEECCCCCCHHHHH	34.11	33845483
1067	Phosphorylation	KFHWKQRSSDTFRRR EEECCCCCCHHHHHH	30.03	20860994
1067 (in isoform 2)	Ubiquitination	-	30.03	21890473
1068	Phosphorylation	FHWKQRSSDTFRRRR EECCCCCCHHHHHHH	42.74	20860994
1070	Phosphorylation	WKQRSSDTFRRRRWR CCCCCCHHHHHHHHH	22.46	28102081
1079	Ubiquitination	RRRRWRRKMAPSETH HHHHHHHHCCCCCCC	30.73	33845483
1081	Ubiquitination	RRWRRKMAPSETHGA HHHHHHCCCCCCCCH	13.91	23503661
1091	Ubiquitination	ETHGAAAIFKLEGAL CCCCHHHHEEEECCC	2.41	21963094
1095	Ubiquitination	AAAIFKLEGALGADT HHHHEEEECCCCCCC	42.90	23503661
1096	Ubiquitination	AAIFKLEGALGADTT HHHEEEECCCCCCCC	36.22	21963094
1096 (in isoform 6)	Ubiquitination	-	36.22	21890473
1097	Ubiquitination	AIFKLEGALGADTTE HHEEEECCCCCCCCC	8.08	23503661
1100	Ubiquitination	KLEGALGADTTEDGD EEECCCCCCCCCCCC	16.30	23503661
1102	Phosphorylation	EGALGADTTEDGDEK ECCCCCCCCCCCCHH	31.39	29514088
1102	Ubiquitination	EGALGADTTEDGDEK ECCCCCCCCCCCCHH	31.39	23503661
1103	Phosphorylation	GALGADTTEDGDEKS CCCCCCCCCCCCHHH	32.40	30266825
1105	Ubiquitination	LGADTTEDGDEKSLE CCCCCCCCCCHHHHH	68.69	23503661
1109	Acetylation	TTEDGDEKSLEKQKH CCCCCCHHHHHHHHC	66.15	26051181
1109	Ubiquitination	TTEDGDEKSLEKQKH CCCCCCHHHHHHHHC	66.15	21906983
1109 (in isoform 1)	Ubiquitination	-	66.15	21890473
1109 (in isoform 3)	Ubiquitination	-	66.15	21890473
1109 (in isoform 5)	Ubiquitination	-	66.15	21890473
1110	Phosphorylation	TEDGDEKSLEKQKHS CCCCCHHHHHHHHCH	39.45	30266825
1113	Ubiquitination	GDEKSLEKQKHSATT CCHHHHHHHHCHHEE	70.69	23503661
1115	Ubiquitination	EKSLEKQKHSATTVF HHHHHHHHCHHEEEE	51.07	23503661
1126	Phosphorylation	TTVFGANTPIVSCNF EEEECCCCCEEECCC	17.54	27050516
1132	Ubiquitination	NTPIVSCNFDRVYIY CCCEEECCCCEEEEE	34.05	27667366
1137	Phosphorylation	SCNFDRVYIYHLRCY ECCCCEEEEEEHHHH	9.17	23312004
1163	Phosphorylation	KDSFSDPYAHICFLH CCCCCCCCCEEEEEE	18.79	-
1174	Phosphorylation	CFLHRSKTTEIIHST EEEECCCCCCEECCC	30.79	-
1181	Phosphorylation	TTEIIHSTLNPTWDQ CCCEECCCCCCCCCC	19.18	-
1181 (in isoform 2)	Ubiquitination	-	19.18	21890473
1195 (in isoform 2)	Ubiquitination	-	6.12	21890473
1202	Ubiquitination	VEIYGEPQTVLQNPP EEECCCCEEHHCCCC	39.68	23000965
1205	Ubiquitination	YGEPQTVLQNPPKVI CCCCEEHHCCCCCEE	4.65	23000965
1205 (in isoform 2)	Ubiquitination	-	4.65	-
1206	Ubiquitination	GEPQTVLQNPPKVIM CCCEEHHCCCCCEEE	56.92	23000965
1210	Ubiquitination	TVLQNPPKVIMELFD EHHCCCCCEEECCCC	45.72	29901268
1210 (in isoform 6)	Ubiquitination	-	45.72	21890473
1219	Ubiquitination	IMELFDNDQVGKDEF EECCCCCCCCCCCCC	46.52	23503661
1223	Ubiquitination	FDNDQVGKDEFLGRS CCCCCCCCCCCCCCC	56.05	21906983
1223 (in isoform 1)	Ubiquitination	-	56.05	21890473
1223 (in isoform 3)	Ubiquitination	-	56.05	21890473
1224	Ubiquitination	DNDQVGKDEFLGRSI CCCCCCCCCCCCCCC	46.05	23503661
1224 (in isoform 6)	Ubiquitination	-	46.05	21890473
1229	Ubiquitination	GKDEFLGRSIFSPVV CCCCCCCCCCCCCEE	28.82	23503661
1232 (in isoform 2)	Ubiquitination	-	7.72	-
1233	Phosphorylation	FLGRSIFSPVVKLNS CCCCCCCCCEECCCC	18.34	22985185
1234	Ubiquitination	LGRSIFSPVVKLNSE CCCCCCCCEECCCCC	24.95	23503661
1237	Ubiquitination	SIFSPVVKLNSEMDI CCCCCEECCCCCCCC	42.03	21906983
1237 (in isoform 1)	Ubiquitination	-	42.03	21890473
1237 (in isoform 3)	Ubiquitination	-	42.03	21890473
1240	Phosphorylation	SPVVKLNSEMDITPK CCEECCCCCCCCCHH	44.74	-
1247	Ubiquitination	SEMDITPKLLWHPVM CCCCCCHHHCEEECC	47.78	23503661
1256	Ubiquitination	LWHPVMNGDKACGDV CEEECCCCCCCCCCE	21.50	27667366
1261	Ubiquitination	MNGDKACGDVLVTAE CCCCCCCCCEEEEEE	32.68	33845483
1274	Malonylation	AELILRGKDGSNLPI EEEEECCCCCCCCCC	53.10	26320211
1274	Ubiquitination	AELILRGKDGSNLPI EEEEECCCCCCCCCC	53.10	33845483
1294	Ubiquitination	APNLYMVPQGIRPVV CCCEEECCCCCCCHH	15.34	23503661
1300	Ubiquitination	VPQGIRPVVQLTAIE CCCCCCCHHHHHHHH	2.85	23503661
1302 (in isoform 2)	Ubiquitination	-	33.07	-
1317	Acetylation	AWGLRNMKNFQMASI HHHHHCCCCEEEEEC	59.15	155465
1321 (in isoform 5)	Ubiquitination	-	2.50	21890473
1326	Ubiquitination	FQMASITSPSLVVEC EEEEECCCCCEEEEE	15.72	23000965
1329	Ubiquitination	ASITSPSLVVECGGE EECCCCCEEEEECCE	5.93	23000965
1330	Ubiquitination	SITSPSLVVECGGER ECCCCCEEEEECCEE	3.90	23000965
1331	Ubiquitination	ITSPSLVVECGGERV CCCCCEEEEECCEEE	6.46	23000965
1333	Ubiquitination	SPSLVVECGGERVES CCCEEEEECCEEEEE	6.00	23503661
1334	Ubiquitination	PSLVVECGGERVESV CCEEEEECCEEEEEE	27.73	23000965
1334 (in isoform 5)	Ubiquitination	-	27.73	21890473
1335	Ubiquitination	SLVVECGGERVESVV CEEEEECCEEEEEEE	31.06	23000965
1343	Ubiquitination	ERVESVVIKNLKKTP EEEEEEEEECCCCCC	1.99	21963094
1344	Ubiquitination	RVESVVIKNLKKTPN EEEEEEEECCCCCCC	44.62	23000965
1347	Ubiquitination	SVVIKNLKKTPNFPS EEEEECCCCCCCCCC	65.09	23000965
1348	Malonylation	VVIKNLKKTPNFPSS EEEECCCCCCCCCCC	72.83	26320211
1348	Ubiquitination	VVIKNLKKTPNFPSS EEEECCCCCCCCCCC	72.83	23000965
1352	Ubiquitination	NLKKTPNFPSSVLFM CCCCCCCCCCCCEEE	6.99	29967540
1363	Ubiquitination	VLFMKVFLPKEELYM CEEEEEECCHHHHCC	7.11	33845483
1365	Acetylation	FMKVFLPKEELYMPP EEEEECCHHHHCCCC	67.00	66727349
1365	Ubiquitination	FMKVFLPKEELYMPP EEEEECCHHHHCCCC	67.00	29967540
1369	Phosphorylation	FLPKEELYMPPLVIK ECCHHHHCCCCEEEE	15.74	-
1373	Ubiquitination	EELYMPPLVIKVIDH HHHCCCCEEEEEECC	5.25	33845483
1374 (in isoform 2)	Ubiquitination	-	4.99	-
1376	Acetylation	YMPPLVIKVIDHRQF CCCCEEEEEECCCCC	26.17	27452117
1376	Ubiquitination	YMPPLVIKVIDHRQF CCCCEEEEEECCCCC	26.17	33845483
1379	Ubiquitination	PLVIKVIDHRQFGRK CEEEEEECCCCCCCC	33.63	23503661
1384	Ubiquitination	VIDHRQFGRKPVVGQ EECCCCCCCCCCCCE	28.50	23503661
1386	Malonylation	DHRQFGRKPVVGQCT CCCCCCCCCCCCEEE	42.41	26320211
1386	Ubiquitination	DHRQFGRKPVVGQCT CCCCCCCCCCCCEEE	42.41	33845483
1393	Phosphorylation	KPVVGQCTIERLDRF CCCCCEEEEEEHHHC	20.27	23898821
1394 (in isoform 2)	Ubiquitination	-	3.69	21890473
1395	Ubiquitination	VVGQCTIERLDRFRC CCCEEEEEEHHHCCC	29.10	33845483
1398	Ubiquitination	QCTIERLDRFRCDPY EEEEEEHHHCCCCCC	54.62	23503661
1403	Ubiquitination	RLDRFRCDPYAGKED EHHHCCCCCCCCCCC	34.68	33845483
1408	Ubiquitination	RCDPYAGKEDIVPQL CCCCCCCCCCCHHHH	44.00	33845483
1414 (in isoform 2)	Ubiquitination	-	44.71	-
1416	2-Hydroxyisobutyrylation	EDIVPQLKASLLSAP CCCHHHHHHHHHCCC	30.59	-
1416	Methylation	EDIVPQLKASLLSAP CCCHHHHHHHHHCCC	30.59	115973567
1416	Ubiquitination	EDIVPQLKASLLSAP CCCHHHHHHHHHCCC	30.59	33845483
1418	Phosphorylation	IVPQLKASLLSAPPC CHHHHHHHHHCCCCC	28.40	28674419
1418	Ubiquitination	IVPQLKASLLSAPPC CHHHHHHHHHCCCCC	28.40	23503661
1423	Ubiquitination	KASLLSAPPCRDIVI HHHHHCCCCCCEEEE	25.75	33845483
1423 (in isoform 6)	Ubiquitination	-	25.75	21890473
1424	Ubiquitination	ASLLSAPPCRDIVIE HHHHCCCCCCEEEEE	26.03	23503661
1429	Ubiquitination	APPCRDIVIEMEDTK CCCCCEEEEEECCCH	3.38	33845483
1432	Sulfoxidation	CRDIVIEMEDTKPLL CCEEEEEECCCHHHH	3.77	28465586
1433	Ubiquitination	RDIVIEMEDTKPLLA CEEEEEECCCHHHHH	50.14	33845483
1436	Ubiquitination	VIEMEDTKPLLASKL EEEECCCHHHHHHHC	46.09	21906983
1436 (in isoform 1)	Ubiquitination	-	46.09	21890473
1436 (in isoform 3)	Ubiquitination	-	46.09	21890473
1441	Phosphorylation	DTKPLLASKLTEKEE CCHHHHHHHCCCCHH	28.32	-
1442	Ubiquitination	TKPLLASKLTEKEEE CHHHHHHHCCCCHHH	54.54	33845483
1443	Ubiquitination	KPLLASKLTEKEEEI HHHHHHHCCCCHHHH	7.48	23503661
1444	Phosphorylation	PLLASKLTEKEEEIV HHHHHHCCCCHHHHH	49.07	-
1444 (in isoform 5)	Ubiquitination	-	49.07	21890473
1446	Ubiquitination	LASKLTEKEEEIVDW HHHHCCCCHHHHHHH	66.25	33845483
1453	Ubiquitination	KEEEIVDWWSKFYAS CHHHHHHHHHHHHHC	7.14	21963094
1456	Ubiquitination	EIVDWWSKFYASSGE HHHHHHHHHHHCCCC	28.77	23000965
1456 (in isoform 3)	Phosphorylation	-	28.77	25159151
1457	Ubiquitination	IVDWWSKFYASSGEH HHHHHHHHHHCCCCC	5.27	23503661
1458	Phosphorylation	VDWWSKFYASSGEHE HHHHHHHHHCCCCCH	14.87	28152594
1460	Phosphorylation	WWSKFYASSGEHEKC HHHHHHHCCCCCHHH	27.74	-
1461	Phosphorylation	WSKFYASSGEHEKCG HHHHHHCCCCCHHHH	39.77	17081983
1461	Ubiquitination	WSKFYASSGEHEKCG HHHHHHCCCCCHHHH	39.77	23000965
1462	Ubiquitination	SKFYASSGEHEKCGQ HHHHHCCCCCHHHHH	37.47	23000965
1465 (in isoform 2)	Ubiquitination	-	45.82	21890473
1466	Ubiquitination	ASSGEHEKCGQYIQK HCCCCCHHHHHHHHH	45.64	21963094
1467	Ubiquitination	SSGEHEKCGQYIQKG CCCCCHHHHHHHHHC	3.60	21963094
1472	Ubiquitination	EKCGQYIQKGYSKLK HHHHHHHHHCCCCEE	28.34	21963094
1474 (in isoform 3)	Phosphorylation	-	18.64	22798277
1475	Ubiquitination	GQYIQKGYSKLKIYN HHHHHHCCCCEEEEE	15.07	23503661
1477	Acetylation	YIQKGYSKLKIYNCE HHHHCCCCEEEEECE	45.36	20167786
1479 (in isoform 2)	Ubiquitination	-	47.05	-
1485	Ubiquitination	LKIYNCELENVAEFE EEEEECEECCEEEEC	6.72	21963094
1489	Ubiquitination	NCELENVAEFEGLTD ECEECCEEEECCCCC	27.61	23503661
1494	Ubiquitination	NVAEFEGLTDFSDTF CEEEECCCCCCHHHH	3.06	33845483
1494 (in isoform 6)	Ubiquitination	-	3.06	21890473
1502	Ubiquitination	TDFSDTFKLYRGKSD CCCHHHHHHHCCCCC	46.86	23503661
1503	Ubiquitination	DFSDTFKLYRGKSDE CCHHHHHHHCCCCCC	2.85	23503661
1507	Acetylation	TFKLYRGKSDENEDP HHHHHCCCCCCCCCC	45.82	-
1507	Malonylation	TFKLYRGKSDENEDP HHHHHCCCCCCCCCC	45.82	26320211
1507	Ubiquitination	TFKLYRGKSDENEDP HHHHHCCCCCCCCCC	45.82	33845483
1507 (in isoform 1)	Ubiquitination	-	45.82	21890473
1508	Phosphorylation	FKLYRGKSDENEDPS HHHHCCCCCCCCCCC	53.64	23663014
1508	Ubiquitination	FKLYRGKSDENEDPS HHHHCCCCCCCCCCC	53.64	23503661
1510	Ubiquitination	LYRGKSDENEDPSVV HHCCCCCCCCCCCCC	70.39	23503661
1513	Ubiquitination	GKSDENEDPSVVGEF CCCCCCCCCCCCEEE	52.97	23503661
1515	Phosphorylation	SDENEDPSVVGEFKG CCCCCCCCCCEEEEC	41.58	-
1521	Ubiquitination	PSVVGEFKGSFRIYP CCCCEEEECEEEEEE	49.71	23503661
1522	Ubiquitination	SVVGEFKGSFRIYPL CCCEEEECEEEEEEC	37.02	23503661
1526	Ubiquitination	EFKGSFRIYPLPDDP EEECEEEEEECCCCC	3.80	23503661
1526 (in isoform 3)	Ubiquitination	-	3.80	21890473
1527	Ubiquitination	FKGSFRIYPLPDDPS EECEEEEEECCCCCC	8.41	23503661
1540	Ubiquitination	PSVPAPPRQFRELPD CCCCCCCHHHCCCCC	47.40	23503661
1561	Ubiquitination	TVRIYIVRGLELQPQ EEEEEEEECCCCCCC	34.13	27667366
1566	Ubiquitination	IVRGLELQPQDNNGL EEECCCCCCCCCCCC	25.00	23000965
1571	Ubiquitination	ELQPQDNNGLCDPYI CCCCCCCCCCCCCCE	53.77	23000965
1572	Ubiquitination	LQPQDNNGLCDPYIK CCCCCCCCCCCCCEE	33.66	23000965
1579	Ubiquitination	GLCDPYIKITLGKKV CCCCCCEEEEECCEE	24.64	23000965
1580	Ubiquitination	LCDPYIKITLGKKVI CCCCCEEEEECCEEE	2.52	23000965
1584	Ubiquitination	YIKITLGKKVIEDRD CEEEEECCEEECCCC	47.16	23000965
1585	Ubiquitination	IKITLGKKVIEDRDH EEEEECCEEECCCCC	46.80	23000965
1586	Ubiquitination	KITLGKKVIEDRDHY EEEECCEEECCCCCC	7.07	23000965
1590	Ubiquitination	GKKVIEDRDHYIPNT CCEEECCCCCCCCCC	21.58	23000965
1591	Ubiquitination	KKVIEDRDHYIPNTL CEEECCCCCCCCCCC	51.79	23000965
1591 (in isoform 2)	Ubiquitination	-	51.79	-
1598	Ubiquitination	DHYIPNTLNPVFGRM CCCCCCCCCHHHHEE	9.66	23000965
1603	Ubiquitination	NTLNPVFGRMYELSC CCCCHHHHEEEEEEE	17.43	23000965
1604	Ubiquitination	TLNPVFGRMYELSCY CCCHHHHEEEEEEEE	17.03	23000965
1616	2-Hydroxyisobutyrylation	SCYLPQEKDLKISVY EEECCCCCCCEEEEE	64.21	-
1620	Ubiquitination	PQEKDLKISVYDYDT CCCCCCEEEEEECCC	4.35	33845483
1621	Phosphorylation	QEKDLKISVYDYDTF CCCCCEEEEEECCCC	17.03	23663014
1623	Phosphorylation	KDLKISVYDYDTFTR CCCEEEEEECCCCCC	11.29	23663014
1625	Phosphorylation	LKISVYDYDTFTRDE CEEEEEECCCCCCCC	10.13	23663014
1627	Phosphorylation	ISVYDYDTFTRDEKV EEEEECCCCCCCCCC	22.22	23663014
1629	Phosphorylation	VYDYDTFTRDEKVGE EEECCCCCCCCCCCC	39.02	24719451
1633	2-Hydroxyisobutyrylation	DTFTRDEKVGETIID CCCCCCCCCCCEEEE	60.88	-
1633	Ubiquitination	DTFTRDEKVGETIID CCCCCCCCCCCEEEE	60.88	33845483
1634	Ubiquitination	TFTRDEKVGETIIDL CCCCCCCCCCEEEEH	8.67	23503661
1636	Ubiquitination	TRDEKVGETIIDLEN CCCCCCCCEEEEHHH	39.56	23503661
1639	Ubiquitination	EKVGETIIDLENRFL CCCCCEEEEHHHHHH	6.89	23503661
1642 (in isoform 2)	Ubiquitination	-	42.48	-
1652	Ubiquitination	FLSRFGSHCGIPEEY HHHHHHCCCCCCHHH	17.75	23503661
1671	Ubiquitination	VNTWRDQLRPTQLLQ CCHHHHHCCHHHHHH	9.20	33845483
1675	Ubiquitination	RDQLRPTQLLQNVAR HHHCCHHHHHHHHHH	42.74	23503661
1682	Ubiquitination	QLLQNVARFKGFPQP HHHHHHHHHCCCCCC	29.53	21963094
1684	Ubiquitination	LQNVARFKGFPQPIL HHHHHHHCCCCCCCC	54.83	33845483
1685	Ubiquitination	QNVARFKGFPQPILS HHHHHHCCCCCCCCC	36.43	27667366
1690	Ubiquitination	FKGFPQPILSEDGSR HCCCCCCCCCCCCCC	5.79	27667366
1692	Phosphorylation	GFPQPILSEDGSRIR CCCCCCCCCCCCCEE	34.07	-
1695	Ubiquitination	QPILSEDGSRIRYGG CCCCCCCCCCEEECC	18.12	23503661
1701	Ubiquitination	DGSRIRYGGRDYSLD CCCCEEECCCCCCCC	18.14	29901268
1703	Ubiquitination	SRIRYGGRDYSLDEF CCEEECCCCCCCCHH	35.02	27667366
1705	Phosphorylation	IRYGGRDYSLDEFEA EEECCCCCCCCHHHH	15.12	-
1705	Ubiquitination	IRYGGRDYSLDEFEA EEECCCCCCCCHHHH	15.12	27667366
1706	Phosphorylation	RYGGRDYSLDEFEAN EECCCCCCCCHHHHH	33.36	-
1714	Ubiquitination	LDEFEANKILHQHLG CCHHHHHHHHHHHCC	54.41	29901268
1717 (in isoform 2)	Ubiquitination	-	19.25	-
1746	Ubiquitination	PEHVETRTLHSTFQP CCCCCCCCCCCCCCC	35.92	23503661
1756 (in isoform 2)	Ubiquitination	-	39.25	-
1759	Ubiquitination	QPNISQGKLQMWVDV CCCCCCCCEEEEEEE	28.10	23503661
1760	Ubiquitination	PNISQGKLQMWVDVF CCCCCCCEEEEEEEC	5.58	23503661
1763 (in isoform 2)	Ubiquitination	-	3.11	21890473
1765	Ubiquitination	GKLQMWVDVFPKSLG CCEEEEEEECCHHHC	22.34	23503661
1776 (in isoform 2)	Ubiquitination	-	35.76	21890473
1778	Ubiquitination	LGPPGPPFNITPRKA HCCCCCCCCCCHHHC	13.38	23503661
1781	Phosphorylation	PGPPFNITPRKAKKY CCCCCCCCHHHCCCE	20.39	28355574
1785	Ubiquitination	FNITPRKAKKYYLRV CCCCHHHCCCEEEEE	18.17	23503661
1789	Phosphorylation	PRKAKKYYLRVIIWN HHHCCCEEEEEEEEE	9.27	29457462
1791	Ubiquitination	KAKKYYLRVIIWNTK HCCCEEEEEEEEECC	11.06	23503661
1792	Ubiquitination	AKKYYLRVIIWNTKD CCCEEEEEEEEECCC	3.25	21963094
1792 (in isoform 6)	Ubiquitination	-	3.25	21890473
1795	Ubiquitination	YYLRVIIWNTKDVIL EEEEEEEEECCCEEE	8.70	23503661
1795 (in isoform 3)	Ubiquitination	-	8.70	21890473
1797	Phosphorylation	LRVIIWNTKDVILDE EEEEEEECCCEEECC	17.39	29457462
1798	Ubiquitination	RVIIWNTKDVILDEK EEEEEECCCEEECCC	46.95	23503661
1799	Ubiquitination	VIIWNTKDVILDEKS EEEEECCCEEECCCC	30.56	23503661
1804	Ubiquitination	TKDVILDEKSITGEE CCCEEECCCCCCCCC	45.30	23503661
1805	Ubiquitination	KDVILDEKSITGEEM CCEEECCCCCCCCCC	46.99	21906983
1805 (in isoform 1)	Ubiquitination	-	46.99	21890473
1805 (in isoform 6)	Ubiquitination	-	46.99	21890473
1806	Phosphorylation	DVILDEKSITGEEMS CEEECCCCCCCCCCC	24.28	22199227
1806	Ubiquitination	DVILDEKSITGEEMS CEEECCCCCCCCCCC	24.28	21963094
1808	Phosphorylation	ILDEKSITGEEMSDI EECCCCCCCCCCCCE	45.70	24245541
1808 (in isoform 3)	Ubiquitination	-	45.70	21890473
1811	Ubiquitination	EKSITGEEMSDIYVK CCCCCCCCCCCEEEE	45.38	21963094
1813	Ubiquitination	SITGEEMSDIYVKGW CCCCCCCCCEEEECC	24.92	27667366
1815	Ubiquitination	TGEEMSDIYVKGWIP CCCCCCCEEEECCCC	3.14	33845483
1816	Phosphorylation	GEEMSDIYVKGWIPG CCCCCCEEEECCCCC	10.91	19060867
1817	Ubiquitination	EEMSDIYVKGWIPGN CCCCCEEEECCCCCC	4.77	23503661
1818	Ubiquitination	EMSDIYVKGWIPGNE CCCCEEEECCCCCCH	31.40	21906983
1818 (in isoform 1)	Ubiquitination	-	31.40	21890473
1819	Ubiquitination	MSDIYVKGWIPGNEE CCCEEEECCCCCCHH	19.94	23503661
1821	Ubiquitination	DIYVKGWIPGNEENK CEEEECCCCCCHHHC	4.22	23503661
1824	Ubiquitination	VKGWIPGNEENKQKT EECCCCCCHHHCCCC	48.32	21963094
1828	Malonylation	IPGNEENKQKTDVHY CCCCHHHCCCCEEEE	57.35	26320211
1828	Ubiquitination	IPGNEENKQKTDVHY CCCCHHHCCCCEEEE	57.35	27667366
1829	Ubiquitination	PGNEENKQKTDVHYR CCCHHHCCCCEEEEE	66.52	27667366
1834	Ubiquitination	NKQKTDVHYRSLDGE HCCCCEEEEEECCCC	18.33	27667366
1835	Phosphorylation	KQKTDVHYRSLDGEG CCCCEEEEEECCCCC	11.18	26356563
1837	Ubiquitination	KTDVHYRSLDGEGNF CCEEEEEECCCCCCC	24.52	23503661
1847	Ubiquitination	GEGNFNWRFVFPFDY CCCCCEEEEEEECCC	20.96	27667366
1866	Malonylation	QLCIVAKKEHFWSID HEEEEEECCCEEECC	46.84	26320211
1876 (in isoform 2)	Ubiquitination	-	27.56	-
1886 (in isoform 2)	Ubiquitination	-	24.59	21890473
1891	Ubiquitination	IIQIWDNDKFSLDDY EEEEECCCCCCHHHH	51.40	21963094
1892 (in isoform 2)	Ubiquitination	-	43.01	-
1901	Ubiquitination	SLDDYLGFLELDLRH CHHHHHCHHEEEECC	4.41	33845483
1902 (in isoform 2)	Ubiquitination	-	6.40	-
1905	Ubiquitination	YLGFLELDLRHTIIP HHCHHEEEECCCCCC	32.08	23503661
1909	Phosphorylation	LELDLRHTIIPAKSP HEEEECCCCCCCCCH	17.73	30266825
1914	Ubiquitination	RHTIIPAKSPEKCRL CCCCCCCCCHHHCCC	62.28	33845483
1915	Phosphorylation	HTIIPAKSPEKCRLD CCCCCCCCHHHCCCC	40.16	22167270
1915	Ubiquitination	HTIIPAKSPEKCRLD CCCCCCCCHHHCCCC	40.16	21963094
1915 (in isoform 6)	Ubiquitination	-	40.16	21890473
1918	Ubiquitination	IPAKSPEKCRLDMIP CCCCCHHHCCCCCCC	28.21	23503661
1918 (in isoform 3)	Ubiquitination	-	28.21	21890473
1919	Ubiquitination	PAKSPEKCRLDMIPD CCCCHHHCCCCCCCC	5.08	23503661
1920	Ubiquitination	AKSPEKCRLDMIPDL CCCHHHCCCCCCCCH	44.80	23503661
1921	Ubiquitination	KSPEKCRLDMIPDLK CCHHHCCCCCCCCHH	8.00	33845483
1923	Ubiquitination	PEKCRLDMIPDLKAM HHHCCCCCCCCHHHC	5.92	27667366
1924	Ubiquitination	EKCRLDMIPDLKAMN HHCCCCCCCCHHHCC	2.10	23503661
1928	Ubiquitination	LDMIPDLKAMNPLKA CCCCCCHHHCCCCCH	53.63	21963094
1928 (in isoform 1)	Ubiquitination	-	53.63	21890473
1929	Ubiquitination	DMIPDLKAMNPLKAK CCCCCHHHCCCCCHH	15.41	21963094
1931	Ubiquitination	IPDLKAMNPLKAKTA CCCHHHCCCCCHHCH	43.54	33845483
1933	Ubiquitination	DLKAMNPLKAKTASL CHHHCCCCCHHCHHH	7.76	23503661
1934	Malonylation	LKAMNPLKAKTASLF HHHCCCCCHHCHHHH	49.44	26320211
1934	Methylation	LKAMNPLKAKTASLF HHHCCCCCHHCHHHH	49.44	109060311
1934	Ubiquitination	LKAMNPLKAKTASLF HHHCCCCCHHCHHHH	49.44	21963094
1935	Ubiquitination	KAMNPLKAKTASLFE HHCCCCCHHCHHHHH	23.32	23503661
1936	2-Hydroxyisobutyrylation	AMNPLKAKTASLFEQ HCCCCCHHCHHHHHH	42.93	-
1936	Malonylation	AMNPLKAKTASLFEQ HCCCCCHHCHHHHHH	42.93	26320211
1936	Ubiquitination	AMNPLKAKTASLFEQ HCCCCCHHCHHHHHH	42.93	27667366
1937	Ubiquitination	MNPLKAKTASLFEQK CCCCCHHCHHHHHHH	26.74	27667366
1939	Phosphorylation	PLKAKTASLFEQKSM CCCHHCHHHHHHHHC	38.53	26852163
1940	Ubiquitination	LKAKTASLFEQKSMK CCHHCHHHHHHHHCC	5.20	23503661
1942	Ubiquitination	AKTASLFEQKSMKGW HHCHHHHHHHHCCCC	63.49	27667366
1943	Ubiquitination	KTASLFEQKSMKGWW HCHHHHHHHHCCCCC	35.47	33845483
1944	Ubiquitination	TASLFEQKSMKGWWP CHHHHHHHHCCCCCC	45.37	33845483
1945	Phosphorylation	ASLFEQKSMKGWWPC HHHHHHHHCCCCCCE	25.97	17081983
1945	Ubiquitination	ASLFEQKSMKGWWPC HHHHHHHHCCCCCCE	25.97	23503661
1947	Ubiquitination	LFEQKSMKGWWPCYA HHHHHHCCCCCCEEE	59.47	21963094
1948	Ubiquitination	FEQKSMKGWWPCYAE HHHHHCCCCCCEEEE	24.04	23503661
1950	Ubiquitination	QKSMKGWWPCYAEKD HHHCCCCCCEEEECC	5.03	23503661
1953	Ubiquitination	MKGWWPCYAEKDGAR CCCCCCEEEECCCCE	17.45	23503661
1955	Ubiquitination	GWWPCYAEKDGARVM CCCCEEEECCCCEEE	25.79	27667366
1956	Ubiquitination	WWPCYAEKDGARVMA CCCEEEECCCCEEEE	53.97	33845483
1963	Ubiquitination	KDGARVMAGKVEMTL CCCCEEEEEEEEEEE	16.29	29901268
1966	Ubiquitination	ARVMAGKVEMTLEIL CEEEEEEEEEEEEHH	6.26	23503661
1969	Phosphorylation	MAGKVEMTLEILNEK EEEEEEEEEEHHCCH	14.03	20068231
1976	Ubiquitination	TLEILNEKEADERPA EEEHHCCHHHCCCCC	58.07	29901268
1982	Ubiquitination	EKEADERPAGKGRDE CHHHCCCCCCCCCCC	43.23	29967540
1995	Ubiquitination	DEPNMNPKLDLPNRP CCCCCCCCCCCCCCC	50.02	29967540
2001	Ubiquitination	PKLDLPNRPETSFLW CCCCCCCCCCCEEEE	28.61	21963094
2004	Phosphorylation	DLPNRPETSFLWFTN CCCCCCCCEEEEECC	27.71	25159151
2004	Ubiquitination	DLPNRPETSFLWFTN CCCCCCCCEEEEECC	27.71	33845483
2005	Phosphorylation	LPNRPETSFLWFTNP CCCCCCCEEEEECCC	19.38	29083192
2013	S-palmitoylation	FLWFTNPCKTMKFIV EEEECCCCCCCCHHH	6.59	29575903
2014	Ubiquitination	LWFTNPCKTMKFIVW EEECCCCCCCCHHHH	53.57	21963094
2015	Ubiquitination	WFTNPCKTMKFIVWR EECCCCCCCCHHHHH	32.10	21963094
2017	Ubiquitination	TNPCKTMKFIVWRRF CCCCCCCCHHHHHHH	36.85	33845483
2020	Ubiquitination	CKTMKFIVWRRFKWV CCCCCHHHHHHHHHH	3.51	21963094
2033	Ubiquitination	WVIIGLLFLLILLLF HHHHHHHHHHHHHHH	6.66	21963094
2051	Phosphorylation	LLYSLPNYLSMKIVK HHHHCCCHHCCEECC	9.75	-
2053	Phosphorylation	YSLPNYLSMKIVKPN HHCCCHHCCEECCCC	13.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYOF_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYOF_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYOF_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DYN2_MOUSE	Dnm2	physical	17702744

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-884, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY.
PubMed: 18669648

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1915 AND SER-1945, ANDMASS SPECTROMETRY.
PubMed: 17081983

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY.
PubMed: 15302935

"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer.";
Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.;
Cell 131:1190-1203(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-458 AND TYR-1816, ANDMASS SPECTROMETRY.
PubMed: 18083107