RABL3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RABL3_HUMAN
• UniProt AC: Q5HYI8
• Protein Name: Rab-like protein 3
• Gene Name: RABL3
• Organism: Homo sapiens (Human).
• Sequence Length: 236
• Protein Sequence: MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIIFVHDLTNKKSSQNLRRWSLEALNRDLVPTGVLVTNGDYDQEQFADNQIPLLVIGTKLDQIHETKRHEVLTRTAFLAEDFNPEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLREGNQIPGFPDRKRFGAGTLKSLHYD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASLDRVKVL -----CCCCCCEEEE	29.51	21406692
8	2-Hydroxyisobutyrylation	MASLDRVKVLVLGDS CCCCCCEEEEEECCC	30.64	-
8	Ubiquitination	MASLDRVKVLVLGDS CCCCCCEEEEEECCC	30.64	29967540
15	Phosphorylation	KVLVLGDSGVGKSSL EEEEECCCCCCHHHH	33.31	20068231
20	Phosphorylation	GDSGVGKSSLVHLLC CCCCCCHHHHHHHHH	23.99	21406692
21	Phosphorylation	DSGVGKSSLVHLLCQ CCCCCHHHHHHHHHC	37.59	21406692
36	Phosphorylation	NQVLGNPSWTVGCSV CCCCCCCCEEECEEE	39.10	21406692
38	Phosphorylation	VLGNPSWTVGCSVDV CCCCCCEEECEEEEE	16.03	21406692
42	Phosphorylation	PSWTVGCSVDVRVHD CCEEECEEEEEEEEE	18.54	21406692
51	Ubiquitination	DVRVHDYKEGTPEEK EEEEEECCCCCCCCC	56.58	-
58	Acetylation	KEGTPEEKTYYIELW CCCCCCCCEEEEEEE	39.92	30591753
85	Phosphorylation	KSTRAVFYNSVNGII CCCEEEEEECCCEEE	10.42	-
110	Phosphorylation	SQNLRRWSLEALNRD CHHHHHHCHHHHCCC	17.96	28450419
130	Phosphorylation	VLVTNGDYDQEQFAD EEEECCCCCHHHHCC	22.41	23532336
156	2-Hydroxyisobutyrylation	LDQIHETKRHEVLTR HHHHHHHHHHHHHHH	49.09	-
156	Ubiquitination	LDQIHETKRHEVLTR HHHHHHHHHHHHHHH	49.09	29967540
180	Glutathionylation	PEEINLDCTNPRYLA HHHCCCCCCCHHHCC	4.45	22555962
185	Phosphorylation	LDCTNPRYLAAGSSN CCCCCHHHCCCCCCC	11.27	29496907
191	Phosphorylation	RYLAAGSSNAVKLSR HHCCCCCCCCHHHHH	28.08	22461510
195	Ubiquitination	AGSSNAVKLSRFFDK CCCCCCHHHHHHHHH	38.03	29967540
202	Ubiquitination	KLSRFFDKVIEKRYF HHHHHHHHHHHHHHH	39.70	24816145
206	Ubiquitination	FFDKVIEKRYFLREG HHHHHHHHHHHHCCC	41.07	-
207	Ubiquitination	FDKVIEKRYFLREGN HHHHHHHHHHHCCCC	18.04	21890473
221	Ubiquitination	NQIPGFPDRKRFGAG CCCCCCCCCCCCCCC	67.48	21890473
222	Methylation	QIPGFPDRKRFGAGT CCCCCCCCCCCCCCC	32.08	115490007
229	Phosphorylation	RKRFGAGTLKSLHYD CCCCCCCCCCCCCCC	30.40	28857561
231	Methylation	RFGAGTLKSLHYD-- CCCCCCCCCCCCC--	51.30	42366077
231	Ubiquitination	RFGAGTLKSLHYD-- CCCCCCCCCCCCC--	51.30	21906983
232	Phosphorylation	FGAGTLKSLHYD--- CCCCCCCCCCCC---	24.40	29214152
235	Phosphorylation	GTLKSLHYD------ CCCCCCCCC------	28.74	-
245	Ubiquitination	---------------- ----------------		21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RABL3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RABL3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RABL3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
SIR5_HUMAN	SIRT5	physical	28514442
RELL1_HUMAN	RELL1	physical	28514442
RHOA_HUMAN	RHOA	physical	28514442
GDS1_HUMAN	RAP1GDS1	physical	28514442
STOM_HUMAN	STOM	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.