YIPF5_HUMAN - dbPTM
YIPF5_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YIPF5_HUMAN
UniProt AC Q969M3
Protein Name Protein YIPF5
Gene Name YIPF5
Organism Homo sapiens (Human).
Sequence Length 257
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane
Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle . Enriched at the endoplasmic reticulum exit sites. Colocalizes with RA
Protein Description Plays a role in transport between endoplasmic reticulum and Golgi..
Protein Sequence MSGFENLNTDFYQTSYSIDDQSQQSYDYGGSGGPYSKQYAGYDYSQQGRFVPPDMMQPQQPYTGQIYQPTQAYTPASPQPFYGNNFEDEPPLLEELGINFDHIWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMFCLLNLMSMTGVSFGCVASVLGYCLLPMILLSSFAVIFSLQGMVGIILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVFALISVF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationSGFENLNTDFYQTSY
CCCCCCCCCCEECCC		30.5628348404
12PhosphorylationENLNTDFYQTSYSID
CCCCCCCEECCCCCC		17.4328348404
14PhosphorylationLNTDFYQTSYSIDDQ
CCCCCEECCCCCCCC		20.4628348404
15PhosphorylationNTDFYQTSYSIDDQS
CCCCEECCCCCCCCC		11.0228348404
16PhosphorylationTDFYQTSYSIDDQSQ
CCCEECCCCCCCCCC		17.0328348404
17PhosphorylationDFYQTSYSIDDQSQQ
CCEECCCCCCCCCCC		21.2228348404
22PhosphorylationSYSIDDQSQQSYDYG
CCCCCCCCCCCCCCC		36.8628348404
25PhosphorylationIDDQSQQSYDYGGSG
CCCCCCCCCCCCCCC		16.6028348404
26PhosphorylationDDQSQQSYDYGGSGG
CCCCCCCCCCCCCCC		14.6228348404
28PhosphorylationQSQQSYDYGGSGGPY
CCCCCCCCCCCCCCC		18.36-
35PhosphorylationYGGSGGPYSKQYAGY
CCCCCCCCCCCCCCC		31.6025884760
37UbiquitinationGSGGPYSKQYAGYDY
CCCCCCCCCCCCCCC		41.29-
39PhosphorylationGGPYSKQYAGYDYSQ
CCCCCCCCCCCCCCC		13.0121945579
42PhosphorylationYSKQYAGYDYSQQGR
CCCCCCCCCCCCCCC		11.9721945579
44PhosphorylationKQYAGYDYSQQGRFV
CCCCCCCCCCCCCCC		10.4121945579
45PhosphorylationQYAGYDYSQQGRFVP
CCCCCCCCCCCCCCC		17.0921945579
67PhosphorylationQPYTGQIYQPTQAYT
CCCCCCCCCCCCCCC		10.68-
77PhosphorylationTQAYTPASPQPFYGN
CCCCCCCCCCCCCCC		25.8526657352
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YIPF5_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YIPF5_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YIPF5_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AT1A1_HUMANATP1A1physical
26496610
ATPA_HUMANATP5A1physical
26496610
ATPB_HUMANATP5Bphysical
26496610
ATPO_HUMANATP5Ophysical
26496610
CAV1_HUMANCAV1physical
26496610
COX5B_HUMANCOX5Bphysical
26496610
CX6B1_HUMANCOX6B1physical
26496610
PHB_HUMANPHBphysical
26496610
AAAT_HUMANSLC1A5physical
26496610
SSRG_HUMANSSR3physical
26496610
STX3_HUMANSTX3physical
26496610
TAF9_HUMANTAF9physical
26496610
CEPT1_HUMANCEPT1physical
26496610
YIF1A_HUMANYIF1Aphysical
26496610
PHB2_HUMANPHB2physical
26496610
TMCO1_HUMANTMCO1physical
26496610
MPP8_HUMANMPHOSPH8physical
26496610
T161A_HUMANTMEM161Aphysical
26496610
MACOI_HUMANTMEM57physical
26496610
ELOV5_HUMANELOVL5physical
26496610
MBOA7_HUMANMBOAT7physical
26496610
ARI5B_HUMANARID5Bphysical
26496610
YIF1B_HUMANYIF1Bphysical
26496610
S38A5_HUMANSLC38A5physical
26496610
CAVN3_HUMANPRKCDBPphysical
26496610
CAVN1_HUMANPTRFphysical
26496610
RABL3_HUMANRABL3physical
26496610
PTAR1_HUMANPTAR1physical
26496610
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YIPF5_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Immunoaffinity profiling of tyrosine phosphorylation in cancercells.";
Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H.,Zha X.-M., Polakiewicz R.D., Comb M.J.;
Nat. Biotechnol. 23:94-101(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-39 AND TYR-44, AND MASSSPECTROMETRY.

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