GLT16_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLT16_HUMAN
• UniProt AC: Q8N428
• Protein Name: Polypeptide N-acetylgalactosaminyltransferase 16
• Gene Name: GALNT16
• Organism: Homo sapiens (Human).
• Sequence Length: 558
• Subcellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein.
• Protein Description: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor..
• Protein Sequence: MRKIRANAIAILTVAWILGTFYYLWQDNRAHAASSGGRGAQRAGRRSEQLREDRTIPLIVTGTPSKGFDEKAYLSAKQLKAGEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSDLPATSVIITFHNEARSTLLRTVKSVLNRTPANLIQEIILVDDFSSDPEDCLLLTRIPKVKCLRNDRREGLIRSRVRGADVAAATVLTFLDSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPLEQKMTRTDPTRPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQRKKMNCKSFRWYLENVYPELTVPVKEALPGIIKQGVNCLESQGQNTAGDFLLGMGICRGSAKNPQPAQAWLFSDHLIQQQGKCLAATSTLMSSPGSPVILQMCNPREGKQKWRRKGSFIQHSVSGLCLETKPAQLVTSKCQADAQAQQWQLLPHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
55	O-linked_Glycosylation	EQLREDRTIPLIVTG HHHHCCCCCCEEEEC		55824893
61	O-linked_Glycosylation	RTIPLIVTGTPSKGF CCCCEEEECCCCCCC		55828103
63	O-linked_Glycosylation	IPLIVTGTPSKGFDE CCEEEECCCCCCCCH		55828109
80	Ubiquitination	YLSAKQLKAGEDPYR HHCHHHHHCCCCHHH		-
244	Phosphorylation	SPIIDVISLDNFAYL CCCEEEEECCCHHHH		22210691
250	Phosphorylation	ISLDNFAYLAASADL EECCCHHHHHHCCCC		22210691
378	Phosphorylation	AEVWMDEYKQYYYEA EEEHHHHHHHHHHHH		-
411	Phosphorylation	RKKMNCKSFRWYLEN HHCCCCHHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLT16_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLT16_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLT16_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RHG17_HUMAN	ARHGAP17	physical	28514442
IPO8_HUMAN	IPO8	physical	28514442
G3PT_HUMAN	GAPDHS	physical	28514442
S39AB_HUMAN	SLC39A11	physical	28514442
RMND1_HUMAN	RMND1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.