dbPTM

F210B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	F210B_HUMAN
UniProt AC	Q96KR6
Protein Name	Protein FAM210B, mitochondrial {ECO:0000305}
Gene Name	FAM210B {ECO:0000312\|HGNC:HGNC:16102}
Organism	Homo sapiens (Human).
Sequence Length	192
Subcellular Localization	Mitochondrion . Mitochondrion outer membrane Multi-pass membrane protein .
Protein Description	Plays a role in erythroid differentiation. [PubMed: 26968549 Involved in cell proliferation and tumor cell growth suppression]
Protein Sequence	MAGLLALLGPAGRVGARVRPRATWLLGATAPCAPPPLALALLPPRLDARLLRTARGDCRGHQDPSQATGTTGSSVSCTEEKKQSKSQQLKKIFQEYGTVGVSLHIGISLISLGIFYMVVSSGVDMPAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRISITLVSVPLIVRYFRKVGFFKPPAAKP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Phosphorylation	HQDPSQATGTTGSSV CCCHHHCCCCCCCCC	27.68	24114839
70	Phosphorylation	DPSQATGTTGSSVSC CHHHCCCCCCCCCCC	24.51	24114839
74	Phosphorylation	ATGTTGSSVSCTEEK CCCCCCCCCCCCHHH	21.28	24114839
147	Phosphorylation	QSKMAAGTSTFVVAY HHHHCCCCCHHHHHH	21.62	-
148	Phosphorylation	SKMAAGTSTFVVAYA HHHCCCCCHHHHHHH	20.94	-
149	Phosphorylation	KMAAGTSTFVVAYAI HHCCCCCHHHHHHHH	21.93	-
166	Phosphorylation	LFAPVRISITLVSVP HHCCEEEEEEEEEHH	10.04	24719451
168	Phosphorylation	APVRISITLVSVPLI CCEEEEEEEEEHHHH	17.83	24719451
178	Phosphorylation	SVPLIVRYFRKVGFF EHHHHHHHHHHCCCC	9.24	24719451
181	Acetylation	LIVRYFRKVGFFKPP HHHHHHHHCCCCCCC	36.49	18603123
191	Acetylation	FFKPPAAKP------ CCCCCCCCC------	54.06	18603131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of F210B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of F210B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of F210B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of F210B_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of F210B_HUMAN

Related Literatures of Post-Translational Modification