CPEB2_HUMAN - dbPTM
CPEB2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CPEB2_HUMAN
UniProt AC Q7Z5Q1
Protein Name Cytoplasmic polyadenylation element-binding protein 2
Gene Name CPEB2
Organism Homo sapiens (Human).
Sequence Length 589
Subcellular Localization Cytoplasm .
Protein Description May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers (By similarity). Required for cell cycle progression, specifically for the transition from metaphase to anaphase. [PubMed: 26398195]
Protein Sequence MPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTGSMSWGAMHGRDHRRTGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNGRSSLFPIDDGLLDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
89PhosphorylationQQPQSRRSPVSPQLQ
CCCCCCCCCCCHHHH		28.6630266825
92PhosphorylationQSRRSPVSPQLQQQH
CCCCCCCCHHHHHHH		15.4330266825
112PhosphorylationAFLQQRNSYNHHQPL
HHHHHHHCCCCCCCH		29.5127251275
113PhosphorylationFLQQRNSYNHHQPLL
HHHHHHCCCCCCCHH		23.2828555341
149 (in isoform 9)Phosphorylation-41.99-
149 (in isoform 8)Phosphorylation-41.99-
151PhosphorylationHGRDHRRTGNMGIPG
CCCCCCCCCCCCCCC		32.6322210691
154 (in isoform 8)Phosphorylation-5.64-
154 (in isoform 9)Phosphorylation-5.64-
159PhosphorylationGNMGIPGTMNQISPL
CCCCCCCCCHHCCCC		13.9522199227
161 (in isoform 8)Phosphorylation-35.5527251275
161 (in isoform 9)Phosphorylation-35.5527251275
162 (in isoform 8)Phosphorylation-27.0627251275
162PhosphorylationGIPGTMNQISPLKKP
CCCCCCHHCCCCCCC		27.0627251275
162 (in isoform 9)Phosphorylation-27.0627251275
164PhosphorylationPGTMNQISPLKKPFS
CCCCHHCCCCCCCCC		17.8922199227
171PhosphorylationSPLKKPFSGNVIAPP
CCCCCCCCCCCCCCC		37.6822210691
175 (in isoform 8)Phosphorylation-5.74-
175 (in isoform 9)Phosphorylation-5.74-
176 (in isoform 8)Phosphorylation-15.29-
176 (in isoform 9)Phosphorylation-15.29-
183 (in isoform 8)Phosphorylation-41.4328842319
183PhosphorylationAPPKFTRSTPSLTPK
CCCCCCCCCCCCCCC		41.4324719451
183 (in isoform 9)Phosphorylation-41.4328842319
184PhosphorylationPPKFTRSTPSLTPKS
CCCCCCCCCCCCCCH		17.3828555341
188PhosphorylationTRSTPSLTPKSWIED
CCCCCCCCCCHHHCC		32.7722210691
191PhosphorylationTPSLTPKSWIEDNVF
CCCCCCCHHHCCCEE		34.1928555341
204PhosphorylationVFRTDNNSNTLLPLQ
EEECCCCCCCEEEEE		37.1328555341
209 (in isoform 8)Phosphorylation-24.7027732954
209 (in isoform 9)Phosphorylation-24.7027732954
254PhosphorylationYDSLNMHSLENSLID
HHHCCHHHHHHHHHH		26.98-
258PhosphorylationNMHSLENSLIDIMRA
CHHHHHHHHHHHHHH		19.82-
267 (in isoform 8)Phosphorylation-40.7928348404
267 (in isoform 9)Phosphorylation-40.7928348404
275PhosphorylationDPLKGRLSYPHPGTD
CCCCCCCCCCCCCCC		34.9528555341
276PhosphorylationPLKGRLSYPHPGTDN
CCCCCCCCCCCCCCC		15.3428555341
314PhosphorylationDQVGVLNSPTCYSAH
CCEEECCCCCCCCCC		19.8828348404
319PhosphorylationLNSPTCYSAHQNGER
CCCCCCCCCCCCCHH		22.7821712546
371PhosphorylationHKAESKSYFPPKGYA
CCCCCCCCCCCCCEE		24.68-
464PhosphorylationAMIMDRLYGGVCYAG
HHHHHHHHCCCCCCC		16.84-
469PhosphorylationRLYGGVCYAGIDTDP
HHHCCCCCCCCCCCC		12.88-
474PhosphorylationVCYAGIDTDPELKYP
CCCCCCCCCCCCCCC		52.08-
480PhosphorylationDTDPELKYPKGAGRV
CCCCCCCCCCCCCCE		23.85-
495PhosphorylationAFSNQQSYIAAISAR
EECCCHHHHHHHHHH		7.11-
526PhosphorylationPYVLDDQMCDECQGA
CEECCHHHCHHHCCC		3.9124719451
529PhosphorylationLDDQMCDECQGARCG
CCHHHCHHHCCCCCC		24.6624719451
549PhosphorylationFFCANVTCLQYYCEF
HHCCCHHHHHHHHHH		1.6224719451
601Phosphorylation-------------------
-------------------		27251275
620Phosphorylation--------------------------------------
--------------------------------------		24719451
625Phosphorylation-------------------------------------------
-------------------------------------------		24719451
712Phosphorylation----------------------------------------------------------------------------------------------------------------------------------
----------------------------------------------------------------------------------------------------------------------------------		27251275
759Phosphorylation---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		27251275
764Phosphorylation--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		-
859Ubiquitination-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CPEB2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CPEB2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CPEB2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CPEB2_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CPEB2_HUMAN

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Related Literatures of Post-Translational Modification

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