TAF9_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF9_MOUSE
• UniProt AC: Q8VI33
• Protein Name: Transcription initiation factor TFIID subunit 9
• Gene Name: Taf9
• Organism: Mus musculus (Mouse).
• Sequence Length: 264
• Subcellular Localization: Nucleus.
• Protein Description: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity)..
• Protein Sequence: MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKAPAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATSTVQNVLINPSLIGSKNILITTNMVSQNTAESANALKRKREDDDDDDDDDDDDDYDNM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Acetylation	---MESGKMASPKSM ---CCCCCCCCCCCC	40.34	-
8	Phosphorylation	MESGKMASPKSMPKD CCCCCCCCCCCCCHH	29.39	24759943
84	Phosphorylation	CRADQSFTSPPPRDF ECCCCCCCCCCCCHH	45.64	28066266
85	Phosphorylation	RADQSFTSPPPRDFL CCCCCCCCCCCCHHH	33.14	28066266
128	Methylation	CLTAPNYRLKSLQKK EECCCCCHHHHHHHH	42.13	26542203
144	Phosphorylation	PAPAGRITVPRLSVG CCCCCCEEECEEEEC	24.09	25266776
149	Phosphorylation	RITVPRLSVGSVSSR CEEECEEEECCCCCC	26.22	25521595
152	Phosphorylation	VPRLSVGSVSSRPST ECEEEECCCCCCCCC	19.37	22942356
154	Phosphorylation	RLSVGSVSSRPSTPT EEEECCCCCCCCCCC	23.48	25521595
155	Phosphorylation	LSVGSVSSRPSTPTL EEECCCCCCCCCCCC	46.16	27087446
158	Phosphorylation	GSVSSRPSTPTLGTP CCCCCCCCCCCCCCC	46.00	25521595
159	Phosphorylation	SVSSRPSTPTLGTPT CCCCCCCCCCCCCCC	23.99	25521595
161	Phosphorylation	SSRPSTPTLGTPTPQ CCCCCCCCCCCCCCC	37.60	25521595
164	Phosphorylation	PSTPTLGTPTPQTMS CCCCCCCCCCCCEEE	27.40	27087446
166	Phosphorylation	TPTLGTPTPQTMSVS CCCCCCCCCCEEEEE	28.06	25619855
169	Phosphorylation	LGTPTPQTMSVSTKV CCCCCCCEEEEEEEE	16.77	25619855
171	Phosphorylation	TPTPQTMSVSTKVGT CCCCCEEEEEEEECC	19.12	25619855
173	Phosphorylation	TPQTMSVSTKVGTPM CCCEEEEEEEECCCC	18.40	25619855
174	Phosphorylation	PQTMSVSTKVGTPMS CCEEEEEEEECCCCC	27.82	25619855
178	Phosphorylation	SVSTKVGTPMSLTGQ EEEEEECCCCCCCCC	20.85	26643407
181	Phosphorylation	TKVGTPMSLTGQRFT EEECCCCCCCCCEEE	24.79	24759943
183	Phosphorylation	VGTPMSLTGQRFTVQ ECCCCCCCCCEEEEE	24.78	24759943
194	Phosphorylation	FTVQMPASQSPAVKA EEEEECCCCCCCCCC	25.89	26745281
196	Phosphorylation	VQMPASQSPAVKASI EEECCCCCCCCCCCC	16.60	25266776

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF9_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF9_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF9_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TAF9_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.