ZMYM2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZMYM2_MOUSE
• UniProt AC: Q9CU65
• Protein Name: Zinc finger MYM-type protein 2
• Gene Name: Zmym2
• Organism: Mus musculus (Mouse).
• Sequence Length: 1376
• Subcellular Localization: Nucleus .
• Protein Description: May function as a transcription factor..
• Protein Sequence: MDTSSVGTLELTDQTPVLLGSTAMATSLTNVGNSFSGPPNPLVSRSSKFQNSSVEDDDDVVFIEPVQPPPSSAPLVADQRPITFTSSKNEELQGNDPKILPSSKELAPQKGSVSETIVIDDEEDMETNQGQEKSSSNFIERRPSETKNRTNDVDFSSSTFSRSKVNAGVSNSGITTEPDSEIQIANVTTLETGVSSVSDGQLESTDGRDMNLMITHVTSLHNTSLGDGSNGLQSSNFGVNIQTYTPSLTSQTKAGVGPFNPGRMNVAGDVFQNGESAPHHNPDSWISQSASFPRNQKQQGVDSLSPVASLPKQIFQPSNQQPTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQSPAKGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAGNNVLVVDGQQKRFCCQSCVTEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPSDIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLGLRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQEWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMTGSAPPPSPTPNKEMKNKAILCKPLTMTKATYCKPHMQTKSCQTDENWKTEYVPVPIPVPVYVPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPATVEDLKSKVSSDPLDSELLTMTDMMTEEEGKAEASNINSVIIETDIIGSDLTKNSDPDIQSNMPDVPYEPDLDIEIDFPRAAEELDMENEFLLPPVFGEEYEEQPRPRSKKKGTKRKAVSGYQSHDDSSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLVLDELKSSKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQMFEQELNKILRSWQPSILPDGSIFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVSSLCGTDNEDKIATGKRKHEDDEPVFEQVENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRNTLENMLVRVLLVKDIYDKDNYELDEDTD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Phosphorylation	RSSKFQNSSVEDDDD CCCCCCCCCCCCCCC	25.61	25338131
112	Phosphorylation	ELAPQKGSVSETIVI HCCCCCCCCCEEEEE	29.52	25338131
114	Phosphorylation	APQKGSVSETIVIDD CCCCCCCCEEEEECC	30.62	27087446
116	Phosphorylation	QKGSVSETIVIDDEE CCCCCCEEEEECCHH	17.03	27087446
136	Phosphorylation	QGQEKSSSNFIERRP CCCCCCCCCCCCCCC	42.73	23375375
144	Phosphorylation	NFIERRPSETKNRTN CCCCCCCCCCCCCCC	56.96	25266776
146	Phosphorylation	IERRPSETKNRTNDV CCCCCCCCCCCCCCC	37.65	25266776
303	Phosphorylation	QKQQGVDSLSPVASL CCCCCCCCCCCCCCC	28.48	22942356
305	Phosphorylation	QQGVDSLSPVASLPK CCCCCCCCCCCCCCC	22.68	23527152
309	Phosphorylation	DSLSPVASLPKQIFQ CCCCCCCCCCCCCCC	45.50	28833060
349	Phosphorylation	TAYQRKGSAHLFCST CHHHCCCCCEEEEEC	18.62	22807455
355	Phosphorylation	GSAHLFCSTTCLSSF CCCEEEEECHHHHHC	21.29	22807455
357	Phosphorylation	AHLFCSTTCLSSFSH CEEEEECHHHHHCCC	8.65	22807455
363	Phosphorylation	TTCLSSFSHKPAPKK CHHHHHCCCCCCCCC	32.33	22807455
594	Phosphorylation	KRNSLPQYQATMPDG HHCCCCCEEEECCCC	9.74	-
623	Phosphorylation	QALSMQSSPNGQFVA HHHHCCCCCCCCEEC	12.90	22006019
670	Phosphorylation	SKTCSDDYKKLHCIV HHHCCCHHHHHHEEE	18.27	-
679	Phosphorylation	KLHCIVTYCEYCQEE HHHEEEHHHHHHHHH	3.41	-
682	Phosphorylation	CIVTYCEYCQEEKTL EEEHHHHHHHHHCCH	8.89	-
728	Phosphorylation	LRCVTCNYCSQLCKK CEEEECHHHHHHHHC	8.81	-
818	Phosphorylation	KGPENLHYDQGCQTS CCCCCCCCCCCCCCC	17.09	-
830	Phosphorylation	QTSRTKMTGSAPPPS CCCCCCCCCCCCCCC	29.55	25159016
832	Phosphorylation	SRTKMTGSAPPPSPT CCCCCCCCCCCCCCC	28.56	25159016
837	Phosphorylation	TGSAPPPSPTPNKEM CCCCCCCCCCCCHHH	47.37	26824392
839	Phosphorylation	SAPPPSPTPNKEMKN CCCCCCCCCCHHHCC	43.78	21149613
861	Phosphorylation	LTMTKATYCKPHMQT CCCCCCCCCCCCCCC	11.88	-
937	Ubiquitination	PATVEDLKSKVSSDP CCCHHHHHHHHCCCC	61.63	22790023
1051	Phosphorylation	GTKRKAVSGYQSHDD CCCCCCCCCCCCCCC	36.32	21149613
1053	Phosphorylation	KRKAVSGYQSHDDSS CCCCCCCCCCCCCCC	10.19	21149613
1055	Phosphorylation	KAVSGYQSHDDSSDN CCCCCCCCCCCCCCC	22.02	21149613
1059	Phosphorylation	GYQSHDDSSDNSECS CCCCCCCCCCCCCCC	45.72	21149613
1060	Phosphorylation	YQSHDDSSDNSECSF CCCCCCCCCCCCCCC	48.05	21149613
1063	Phosphorylation	HDDSSDNSECSFPFK CCCCCCCCCCCCCCE	44.99	21149613
1066	Phosphorylation	SSDNSECSFPFKYTY CCCCCCCCCCCEEEE	31.72	25293948
1098	Ubiquitination	LLVLDELKSSKSVKL EEHHHHHHCCCCCCC	51.11	22790023
1279	Acetylation	EDKIATGKRKHEDDE CCCCCCCCCCCCCCC	54.65	91103
1325	Phosphorylation	NQRMDVFYLQPECSS HHCCEEEEECCCCCC	12.32	23567750
1331	Phosphorylation	FYLQPECSSSTDSPV EEECCCCCCCCCCCC	26.17	23567750
1341	Phosphorylation	TDSPVWYTSTSLDRN CCCCCEEECCCCCHH	15.15	23567750
1361	Acetylation	LVRVLLVKDIYDKDN HHHHHHHHHHHCCCC	38.08	7619251
1375	Phosphorylation	NYELDEDTD------ CCCCCCCCC------	41.37	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZMYM2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZMYM2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZMYM2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ZMYM2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.