KLF5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KLF5_MOUSE
• UniProt AC: Q9Z0Z7
• Protein Name: Krueppel-like factor 5
• Gene Name: Klf5
• Organism: Mus musculus (Mouse).
• Sequence Length: 446
• Subcellular Localization: Nucleus.
• Protein Description: Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes..
• Protein Sequence: MPTRVLTMSARLGPLPQPPAAQDEPVFAQLKPVLGAANPARDAALFSGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGIPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPPAPTQALPEFTSIFSSHQTTAPPQEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNPHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPTLPPVRYNRRSNPDLEKRRIHFCDYNGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCMVCQRSFSRSDHLALHMKRHQN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	AAGPRLPSEELVQTR CCCCCCCCHHHHHHH	48.58	28066266
151	Sumoylation	RPCVTQIKTEPVTIF CCCEEEEECCCEEEE	36.70	-
151	Sumoylation	RPCVTQIKTEPVTIF CCCEEEEECCCEEEE	36.70	-
202	Sumoylation	EVNNIFIKQELPIPD HHCCEEEECCCCCCC	27.28	-
202	Sumoylation	EVNNIFIKQELPIPD HHCCEEEECCCCCCC	27.28	-
340	Phosphorylation	PATLPVNSPTLPPVR CCCCCCCCCCCCCCC	21.35	26824392
348	Phosphorylation	PTLPPVRYNRRSNPD CCCCCCCCCCCCCCC	17.16	-
352	Phosphorylation	PVRYNRRSNPDLEKR CCCCCCCCCCCHHHC	49.86	-
380	Ubiquitination	YTKSSHLKAHLRTHT EECCHHHHHHHHHCC	28.47	-
387	Phosphorylation	KAHLRTHTGEKPYKC HHHHHHCCCCCCEEE	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KLF5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KLF5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KLF5_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HDAC1_MOUSE	Hdac1	physical	18983969
HDAC2_MOUSE	Hdac2	physical	18983969
MTA2_MOUSE	Mta2	physical	18983969
SUMO1_MOUSE	Sumo1	physical	18782761

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.