NID2_MOUSE - dbPTM
NID2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NID2_MOUSE
UniProt AC O88322
Protein Name Nidogen-2
Gene Name Nid2
Organism Mus musculus (Mouse).
Sequence Length 1403
Subcellular Localization Secreted, extracellular space, extracellular matrix, basement membrane.
Protein Description Cell adhesion glycoprotein. Might be involved in osteoblast differentiation. It probably has a role in cell-extracellular matrix interactions..
Protein Sequence MFRDPTAGWLTPPSPLSLLVMLLLLSRVGALRPDELFPYGESWGDQLLPEGDDESSAAVKLAIPLRFYDAQFSSLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRGRILYREDTSGAVLSLAARYVRTGFPLSGSSFTPTHAFLATWEHVGAYEEVSRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKREALYFSLTNTEQSVKNLYQLSNLGIPGVWAFHIGSRFALDNVRPATVGGDPSTARSSALEHPFSHAAALESYTEDSFHYYDENEEDVEYPPVEPGEAPEGHSRIDVSFNSKADPGLVDVGTSSPGSDRASPWPYPAPGNWPSYRETESASLDPQTKQGRPVGEGEVLDFRDPAELLDQMGTRAPAPPEADAALLTPVNEDLGGRNTQSYPEAGPVPSEPDVPVPPLEGEVLPHYPESGHVPPLRGGKYVIGLEDHVGSNDQVFTYNGANLETCEHSHGRCSQHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGRLRVGHIPVHFTDVDLHAYIVGNDGRAYTAISHVPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSIKTNIEGQVPFIPANFTAHITPYKEFYHYRDSVVTSSSSRSFSLTSGSINQTWSYHIDQNITYQACRHAPRHLAIPATQQLTVDRAFALYSEDEGVLRFAVTNQIGPVEVDSAPVGVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGDGRSCVDVNECATGFHRCGPNSVCVNLVGSYRCECRSGYEFADDQHTCILIAPPPNPCLDGSHTCAPEGQARCIHHGGSSFSCACLPGFIGTGHQCSDVDECAENRCHEAAICYNTPGSFSCRCQPGYRGDGFHCTSDTVPEDSISGLKPCEYQQRYAQTQHAYPGSRIHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPGSTPPHCGPPPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQGTRSQPGTRPACIPTVAPPVVRPTPRPDVTPPSVGTFLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAELDGSERKVLFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSIVSYADHFYHTDWRRDGVISVNKDSGQFTDEFLPEQRSHLYGITAVYPYCPTGRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
85PhosphorylationGTNGIISTQDFPRET
ECCCEEECCCCCCCC
23.0426239621
129PhosphorylationILYREDTSGAVLSLA
EEEECCCCHHHHHHH
36.7629109428
345PhosphorylationGHSRIDVSFNSKADP
CCCCEEEEECCCCCC
18.2427180971
348PhosphorylationRIDVSFNSKADPGLV
CEEEEECCCCCCCCE
27.4927180971
361PhosphorylationLVDVGTSSPGSDRAS
CEEECCCCCCCCCCC
32.8725338131
384PhosphorylationNWPSYRETESASLDP
CCCCCCCCCCCCCCC
26.6627180971
386PhosphorylationPSYRETESASLDPQT
CCCCCCCCCCCCCCC
30.4926824392
681N-linked_GlycosylationQVPFIPANFTAHITP
CCCCCCCCEEEEECC
29.4619349973
716N-linked_GlycosylationSLTSGSINQTWSYHI
EEECCCCCEEEEEEE
34.62-
726N-linked_GlycosylationWSYHIDQNITYQACR
EEEEECCCEEHHHHC
25.48-
1058PhosphorylationRESLLEHYGGTPRDD
HHHHHHHCCCCCCCC
14.1024719451
1061PhosphorylationLLEHYGGTPRDDQYV
HHHHCCCCCCCCCCC
15.7024719451
1152N-linked_GlycosylationQIGHLPLNGSRLQKD
EEECCCCCCHHHHHH
44.44-
1248MethylationAELDGSERKVLFHTD
EECCCCCCEEEEECC
35.7616289347
1272PhosphorylationDPIRGNLYWTDWNRE
ECCCCCEEEECCCCC
15.4029899451
1274PhosphorylationIRGNLYWTDWNREAP
CCCCEEEECCCCCCC
19.9925521595
1336MethylationTLPDGTGRRVIQNHL
ECCCCCCCHHHHHCC
29.5424129315

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NID2_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NID2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NID2_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of NID2_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NID2_MOUSE

loading...

Related Literatures of Post-Translational Modification
N-linked Glycosylation
ReferencePubMed
"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.";
Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,Schiess R., Aebersold R., Watts J.D.;
Nat. Biotechnol. 27:378-386(2009).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-681, AND MASSSPECTROMETRY.

TOP