WDR33_MOUSE - dbPTM
WDR33_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WDR33_MOUSE
UniProt AC Q8K4P0
Protein Name pre-mRNA 3' end processing protein WDR33
Gene Name Wdr33
Organism Mus musculus (Mouse).
Sequence Length 1330
Subcellular Localization Nucleus .
Protein Description Essential for both cleavage and polyadenylation of pre-mRNA 3' ends..
Protein Sequence MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESSEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPISQIPQGFQQPHPSQQMPLVPQMGPPGPQGQFRAPGPQGQMGPQGPPMHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPASQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPASQGIQGPLMGLNPRGMQGPPGPRENQGPAPQGLMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDTRGPPNHHLGPMSERRHEQSGGPEHGPDRGPFRGGQDCRGPPDRRGSHPDFPDDFRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFNEGDGRGAARGPPGAWEGRRPGDDRFPRDPDDPRFRGRREESFRRGAPPRHEGRAPPRGRDNFPGPDDFGPEEGFDASDEAARGRDLRGRGRGTPRGGSRKCLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDAPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGSGTSEHREMEAQGGPSEDRGSKGRGGPGPSQRVPKSGRSSSLDGDHHDGYHRDEPFGGPPGSSSSSRGARSGSNWGRGSNMNSGPPRRGTSRGSGRGR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MATEIGSPP
------CCCCCCCCC		25.83-
3Phosphorylation-----MATEIGSPPR
-----CCCCCCCCCC		39.7421930439
7Phosphorylation-MATEIGSPPRFFHM
-CCCCCCCCCCCCCC		37.0726824392
16DimethylationPRFFHMPRFQHQAPR
CCCCCCCCCCCCCCH		35.96-
16MethylationPRFFHMPRFQHQAPR
CCCCCCCCCCCCCCH		35.9630763439
42PhosphorylationQQAMQQLTFDGKRMR
HHHHHHHHCCHHHHH		18.4930635358
46AcetylationQQLTFDGKRMRKAVN
HHHHCCHHHHHHHHH		44.8823806337
46UbiquitinationQQLTFDGKRMRKAVN
HHHHCCHHHHHHHHH		44.8822790023
196SuccinylationQSNMNNVKMFQAHKE
HHCCCCHHHHHHHHH		35.8026388266
321AcetylationLFDIRNLKEELQVFR
HHHHCCHHHHHHHHH		53.3319859221
776MethylationPLMGLNPRGMQGPPG
CCCCCCCCCCCCCCC		52.74-
890PhosphorylationPARGPHPSQGPIPFQ
CCCCCCCCCCCCCHH		44.7428285833
909MethylationPLLGDGPRAPFNQEG
CCCCCCCCCCCCCCC		61.4924129315
909Asymmetric dimethylargininePLLGDGPRAPFNQEG
CCCCCCCCCCCCCCC		61.49-
981MethylationGPEHGPDRGPFRGGQ
CCCCCCCCCCCCCCC		58.7924129315
999PhosphorylationGPPDRRGSHPDFPDD
CCCCCCCCCCCCCCC		29.9926824392
1023MethylationKRFGHRLREFEGRGG
CCHHHHHHHCCCCCC		46.6530989887
1028MethylationRLREFEGRGGPLPQE
HHHHCCCCCCCCCHH		39.4324129315
1060MethylationEFNEGDGRGAARGPP
CCCCCCCCCCCCCCC		36.0058860289
1137MethylationDASDEAARGRDLRGR
CCCHHHHHCCCCCCC		47.9616289355
1139MethylationSDEAARGRDLRGRGR
CHHHHHCCCCCCCCC		33.9518959313
1175PhosphorylationEGGRKPDSWDGNREP
CCCCCCCCCCCCCCC		35.2824719451
1204PhosphorylationHPPHDGHSPASRERS
CCCCCCCCHHHHHHH		27.9127087446
1207PhosphorylationHDGHSPASRERSSSL
CCCCCHHHHHHHHHC		37.7525159016
1211PhosphorylationSPASRERSSSLQGMD
CHHHHHHHHHCCCCC		21.3726239621
1212PhosphorylationPASRERSSSLQGMDM
HHHHHHHHHCCCCCH		41.0926239621
1213PhosphorylationASRERSSSLQGMDMA
HHHHHHHHCCCCCHH		26.4222942356
1221PhosphorylationLQGMDMASLPPRKRP
CCCCCHHHCCCCCCC		34.4728833060
1256MethylationEDRGSKGRGGPGPSQ
CCCCCCCCCCCCCCC		51.1124129315
1271PhosphorylationRVPKSGRSSSLDGDH
CCCCCCCCCCCCCCC		28.0125159016
1272PhosphorylationVPKSGRSSSLDGDHH
CCCCCCCCCCCCCCC		33.2925159016
1273PhosphorylationPKSGRSSSLDGDHHD
CCCCCCCCCCCCCCC		31.5530635358
1309MethylationRSGSNWGRGSNMNSG
CCCCCCCCCCCCCCC		36.6624129315
1309Asymmetric dimethylarginineRSGSNWGRGSNMNSG
CCCCCCCCCCCCCCC		36.66-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WDR33_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WDR33_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WDR33_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of WDR33_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WDR33_MOUSE

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Related Literatures of Post-Translational Modification

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