dbPTM

DDX47_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DDX47_MOUSE
UniProt AC	Q9CWX9
Protein Name	Probable ATP-dependent RNA helicase DDX47
Gene Name	Ddx47
Organism	Mus musculus (Mouse).
Sequence Length	455
Subcellular Localization	Nucleus, nucleolus. Localizes in the nucleolar-organizing region during ribosome biogenesis..
Protein Description	Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA precursors (By similarity)..
Protein Sequence	MAADEEPDSPSGALQTAAEEEETKTFKDLGVTDVLCEACDQLGWAKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQCAVIVGGIDSMSQSLALAKKPHIVIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYLFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPVFPTQDEEVMMLTERVNEAQRFARMELREHGEKKKRKREDAGDDDDKEGAIGVRNKVAGGKMKKRKGR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAADEEPDS ------CCCCCCCCC	24.50	-
9	Phosphorylation	AADEEPDSPSGALQT CCCCCCCCCCCHHHH	31.51	26824392
11	Phosphorylation	DEEPDSPSGALQTAA CCCCCCCCCHHHHHH	40.42	26824392
16	Phosphorylation	SPSGALQTAAEEEET CCCCHHHHHHHHHHH	28.78	25619855
23	Phosphorylation	TAAEEEETKTFKDLG HHHHHHHHCCHHHCC	38.37	25619855
149	Phosphorylation	KPHIVIATPGRLIDH CCCEEEECCCCHHHH	18.36	-
193	Acetylation	TEVDKILKVIPRDRK HHHHHHHHHCCCCCC	41.41	22826441

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DDX47_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DDX47_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DDX47_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DDX47_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DDX47_MOUSE

Related Literatures of Post-Translational Modification