| UniProt ID | TPR_MOUSE | |
|---|---|---|
| UniProt AC | F6ZDS4 | |
| Protein Name | Nucleoprotein TPR | |
| Gene Name | Tpr | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 2431 | |
| Subcellular Localization |
Nucleus . Nucleus membrane Peripheral membrane protein Nucleoplasmic side . Nucleus envelope . Nucleus, nuclear pore complex . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Nucleus membrane Peripheral membrane |
|
| Protein Description | Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Negatively regulates both the association of CTE-containing mRNA with large polyribosomes and translation initiation. Does not play any role in Rev response element (RRE)-mediated export of unspliced mRNAs. Implicated in nuclear export of mRNAs transcribed from heat shock gene promoters; associates both with chromatin in the HSP70 promoter and with mRNAs transcribed from this promoter under stress-induced conditions. Plays a limited role in the regulation of nuclear protein export. Modulates the nucleocytoplasmic transport of activated MAPK1/ERK2 and huntingtin/HTT and may serve as a docking site for the XPO1/CRM1-mediated nuclear export complex. Plays also a role as a structural and functional element of the perinuclear chromatin distribution; involved in the formation and/or maintenance of NPC-associated perinuclear heterochromatin exclusion zones (HEZs). Finally, acts as a spatial regulator of the spindle-assembly checkpoint (SAC) response ensuring a timely and effective recruitment of spindle checkpoint proteins like MAD1L1 and MAD2L1 to unattached kinetochore during the metaphase-anaphase transition before chromosome congression. Its N-terminus is involved in activation of oncogenic kinases (By similarity).. | |
| Protein Sequence | MTSGGSASRSGHRGVPMTSRGFDGSRRGSLRRAGARETASEAADGAAPAAGLRASPCSLASPSAAAAVAAIPADMAAVLQQVLERPELNKLPKSTQNKLEKFLAEQQSEIDCLKGRHEKFKVESEQQYFEIEKRLSQSQERLVTETRECQNLRLELEKLNNQVKVLTEKTKELETAQDRNLGIQSQFTRAKEELEAEKRDLIRTNERLSQEVEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVAVKYREKRLEQEKELLHNQNSWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKQENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSAKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLFALRELGETREREEQETTSSKIAELQHKLENSLAELEQLRESRQHQMQLVDSIVRQRDMYRILLSQTTGMAIPLQASSLDDISLLSTPKRSSTSQTVSTPAPEPVIDSTEAIEAKAALKQLQEIFENYKKEKIDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLNSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATLKQHLNNMEAQLASQSTQRTGKGQPGDRDDVDDLKSQLRQAEEQVNDLKERLKTSTSNVEQYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSTVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMTSIRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDLEKQNRLLHDQIEKLSDKVVTSMKDAVQAPLNVSLNEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNVEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQNLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQQLINQQKDPDTEEYRKLLSEKEIHTKRIQQLNEEVGRLKAEIARSNASLTNNQNLIQSLREDLSKARTEKEGIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEELKAQQNKAMETSTQSSGDHQEQHISVQEMQELKDTLSQSETKTKSLEGQVENLQKTLSEKETEARSLQEQTVQLQSELSRLRQDLQDKTTEEQLRQQMNEKTWKTLALAKSKITHLSGVKDQLTKEIEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLERELREHQERHLEQRDEPQEPTNKAPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPVFGNASGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPTNQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTMEAGDQVSEDTVEMPLPKKLKMVTPVGTEEEVMAEESTDGEAETQAYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTSSQDGQGKGDDVIVIDSDDEDDDEENDGEHEDYEEDEDDDDDEEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGAESHQRAADSQNSGEGNTSAAESSFSQEVAREQQPTSASERQTPQAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETAAGDDGDEVFVEAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGISHAMGGRGGINRGNIN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MTSGGSASR ------CCCCCCCCC | 28576409 | ||
| 18 | Phosphorylation | GHRGVPMTSRGFDGS CCCCCCCCCCCCCCC | 24719451 | ||
| 19 | Phosphorylation | HRGVPMTSRGFDGSR CCCCCCCCCCCCCCC | 24719451 | ||
| 55 | Phosphorylation | PAAGLRASPCSLASP CCCCCCCCCCCCCCH | 30352176 | ||
| 58 | Phosphorylation | GLRASPCSLASPSAA CCCCCCCCCCCHHHH | 30352176 | ||
| 61 | Phosphorylation | ASPCSLASPSAAAAV CCCCCCCCHHHHHHH | 30352176 | ||
| 63 | Phosphorylation | PCSLASPSAAAAVAA CCCCCCHHHHHHHHH | 30352176 | ||
| 209 | Phosphorylation | IRTNERLSQEVEYLT HHHCHHHHHHHHHHH | 25338131 | ||
| 214 | Phosphorylation | RLSQEVEYLTEDVKR HHHHHHHHHHHHHHH | 25293948 | ||
| 216 | Phosphorylation | SQEVEYLTEDVKRLN HHHHHHHHHHHHHHH | 25293948 | ||
| 279 | Phosphorylation | NTELKTKTDELLALG HHHHHHHHHHHHHHC | 25890499 | ||
| 326 | Acetylation | TSNEHLQKHVEDLLT CCHHHHHHHHHHHHH | - | ||
| 364 | Ubiquitination | IKLSNLYKSAADDSE HHHHHHHHHHCCCHH | - | ||
| 386 | Acetylation | RAVDELHKLLKEAGE HHHHHHHHHHHHHHH | - | ||
| 419 | Acetylation | MEKEMLEKIGKLEKE HHHHHHHHHHHHHHH | - | ||
| 438 | Ubiquitination | NDLLSATKRKGAILS HHHHHHHHHCCCCCC | 27667366 | ||
| 445 | Phosphorylation | KRKGAILSEEELAAM HHCCCCCCHHHHHCC | 26239621 | ||
| 453 | Phosphorylation | EEELAAMSPTAAAVA HHHHHCCCHHHHHHH | 25521595 | ||
| 455 | Phosphorylation | ELAAMSPTAAAVAKI HHHCCCHHHHHHHHH | 22942356 | ||
| 464 | Ubiquitination | AAVAKIVKPGMKLTE HHHHHHHCCCCCHHH | 27667366 | ||
| 502 | Acetylation | KYLDEIVKEVEAKAP HHHHHHHHHHHHHCH | - | ||
| 507 | Ubiquitination | IVKEVEAKAPILKRQ HHHHHHHHCHHHHHH | 27667366 | ||
| 523 | Acetylation | EEYERAQKAVASLSA HHHHHHHHHHHHHHH | - | ||
| 531 | Acetylation | AVASLSAKLEQAMKE HHHHHHHHHHHHHHH | - | ||
| 531 | Ubiquitination | AVASLSAKLEQAMKE HHHHHHHHHHHHHHH | - | ||
| 548 | Ubiquitination | RLQEDTDKANKHSSV HHHHHHHHHHHHHHH | 27667366 | ||
| 551 | Acetylation | EDTDKANKHSSVLER HHHHHHHHHHHHHHH | 23806337 | ||
| 568 | Ubiquitination | QRMEIQIKDLSQQIR CCEEEEHHHHHHHHH | - | ||
| 596 | Phosphorylation | VIRDEEVSSADISSS CCCCCCCCCCCCCCC | 25777480 | ||
| 597 | Phosphorylation | IRDEEVSSADISSSS CCCCCCCCCCCCCCH | 26824392 | ||
| 601 | Phosphorylation | EVSSADISSSSEVIS CCCCCCCCCCHHHHH | 25521595 | ||
| 602 | Phosphorylation | VSSADISSSSEVISQ CCCCCCCCCHHHHHH | 25777480 | ||
| 603 | Phosphorylation | SSADISSSSEVISQH CCCCCCCCHHHHHHH | 25293948 | ||
| 604 | Phosphorylation | SADISSSSEVISQHL CCCCCCCHHHHHHHH | 25777480 | ||
| 608 | Phosphorylation | SSSSEVISQHLVSYR CCCHHHHHHHHHHCC | 25777480 | ||
| 613 | Phosphorylation | VISQHLVSYRNIEEL HHHHHHHHCCCHHHH | 25777480 | ||
| 614 | Phosphorylation | ISQHLVSYRNIEELQ HHHHHHHCCCHHHHH | 25777480 | ||
| 693 | Phosphorylation | DMYRILLSQTTGMAI HHHHHHHCCCCCCCC | 25777480 | ||
| 695 | Phosphorylation | YRILLSQTTGMAIPL HHHHHCCCCCCCCCC | 25777480 | ||
| 696 | Phosphorylation | RILLSQTTGMAIPLQ HHHHCCCCCCCCCCC | 25777480 | ||
| 705 | Phosphorylation | MAIPLQASSLDDISL CCCCCCCCCCCCCCC | 25159016 | ||
| 706 | Phosphorylation | AIPLQASSLDDISLL CCCCCCCCCCCCCCC | 25159016 | ||
| 711 | Phosphorylation | ASSLDDISLLSTPKR CCCCCCCCCCCCCCC | 25777480 | ||
| 714 | Phosphorylation | LDDISLLSTPKRSST CCCCCCCCCCCCCCC | 26239621 | ||
| 715 | Phosphorylation | DDISLLSTPKRSSTS CCCCCCCCCCCCCCC | 26824392 | ||
| 719 | Phosphorylation | LLSTPKRSSTSQTVS CCCCCCCCCCCCCCC | 23684622 | ||
| 720 | Phosphorylation | LSTPKRSSTSQTVST CCCCCCCCCCCCCCC | 23684622 | ||
| 721 | Phosphorylation | STPKRSSTSQTVSTP CCCCCCCCCCCCCCC | 22942356 | ||
| 722 | Phosphorylation | TPKRSSTSQTVSTPA CCCCCCCCCCCCCCC | 23684622 | ||
| 724 | Phosphorylation | KRSSTSQTVSTPAPE CCCCCCCCCCCCCCC | 25521595 | ||
| 726 | Phosphorylation | SSTSQTVSTPAPEPV CCCCCCCCCCCCCCC | 23684622 | ||
| 727 | Phosphorylation | STSQTVSTPAPEPVI CCCCCCCCCCCCCCC | 26824392 | ||
| 736 | Phosphorylation | APEPVIDSTEAIEAK CCCCCCCCHHHHHHH | 28833060 | ||
| 737 | Phosphorylation | PEPVIDSTEAIEAKA CCCCCCCHHHHHHHH | 28833060 | ||
| 756 | Phosphorylation | LQEIFENYKKEKIDS HHHHHHHHHHHCCCH | 26824392 | ||
| 787 | Acetylation | DLRSQNTKISTQLDF HHHHCCHHHHHHHHH | 23806337 | ||
| 797 | Acetylation | TQLDFASKRYEMLQD HHHHHHHHHHHHHHH | 7669769 | ||
| 822 | Acetylation | SLQERNQKLTATTQK HHHHHHHHCCCHHHH | 23806337 | ||
| 829 | Acetylation | KLTATTQKQEQIINT HCCCHHHHHHHHHHH | 23806337 | ||
| 829 | Ubiquitination | KLTATTQKQEQIINT HCCCHHHHHHHHHHH | - | ||
| 847 | Ubiquitination | DLRGANEKLAVAEVR HHCCCCHHHHHHHHH | 27667366 | ||
| 994 | Phosphorylation | AQLASQSTQRTGKGQ HHHHHHHHCCCCCCC | 22668510 | ||
| 1028 | Ubiquitination | QVNDLKERLKTSTSN HHHHHHHHHHHCCCC | 27667366 | ||
| 1030 | Ubiquitination | NDLKERLKTSTSNVE HHHHHHHHHCCCCHH | 27667366 | ||
| 1044 | Phosphorylation | EQYRAMVTSLEDSLN HHHHHHHHHHHHHHC | - | ||
| 1115 | Phosphorylation | SELKKTLSTVQNEVQ HHHHHHHHHHHHHHH | 28285833 | ||
| 1202 | Acetylation | ESQLLECKASWEERE HHHHHHHHCCHHHHH | - | ||
| 1221 | Phosphorylation | DEVSKSVSRCEDLEK HHHHHHHHCCHHHHH | 20531401 | ||
| 1259 | Phosphorylation | VQAPLNVSLNEEGKS HHCCCCCCCCCCCCC | 26824392 | ||
| 1340 | Phosphorylation | HEELMKKTETMNVVM HHHHHHHHCHHHHHH | 28576409 | ||
| 1501 | Ubiquitination | KIIDIQEKVKTITQV HEEEHHHHHHHHHHH | - | ||
| 1536 | Phosphorylation | AMETSTQSSGDHQEQ HHCHHCCCCCCCCHH | - | ||
| 1546 | Phosphorylation | DHQEQHISVQEMQEL CCCHHHCCHHHHHHH | - | ||
| 1558 | Phosphorylation | QELKDTLSQSETKTK HHHHHHHCCCHHHHH | 27841257 | ||
| 1563 | Ubiquitination | TLSQSETKTKSLEGQ HHCCCHHHHHHHHHH | 27667366 | ||
| 1565 | Ubiquitination | SQSETKTKSLEGQVE CCCHHHHHHHHHHHH | 27667366 | ||
| 1579 | Ubiquitination | ENLQKTLSEKETEAR HHHHHHHCHHHHHHH | 27667366 | ||
| 1581 | Ubiquitination | LQKTLSEKETEARSL HHHHHCHHHHHHHHH | 27667366 | ||
| 1623 | Ubiquitination | RQQMNEKTWKTLALA HHHHHHHHHHHHHHH | 27667366 | ||
| 1625 | Malonylation | QMNEKTWKTLALAKS HHHHHHHHHHHHHHH | 26320211 | ||
| 1625 | Ubiquitination | QMNEKTWKTLALAKS HHHHHHHHHHHHHHH | 27667366 | ||
| 1631 | Malonylation | WKTLALAKSKITHLS HHHHHHHHHHCHHHH | 26320211 | ||
| 1632 | Phosphorylation | KTLALAKSKITHLSG HHHHHHHHHCHHHHC | 24719451 | ||
| 1635 | Phosphorylation | ALAKSKITHLSGVKD HHHHHHCHHHHCCHH | 24719451 | ||
| 1638 | Phosphorylation | KSKITHLSGVKDQLT HHHCHHHHCCHHHHH | 24719451 | ||
| 1650 | Ubiquitination | QLTKEIEELKQRNGA HHHHHHHHHHHHCCC | 27667366 | ||
| 1652 | Ubiquitination | TKEIEELKQRNGALD HHHHHHHHHHCCCHH | 27667366 | ||
| 1654 | Dimethylation | EIEELKQRNGALDQQ HHHHHHHHCCCHHHH | - | ||
| 1654 | Methylation | EIEELKQRNGALDQQ HHHHHHHHCCCHHHH | 54541789 | ||
| 1681 | Phosphorylation | SQYEGRISRLERELR HHHHHHHHHHHHHHH | 25338131 | ||
| 1705 | Ubiquitination | RDEPQEPTNKAPEQQ CCCCCCCCCCCHHHH | 27667366 | ||
| 1707 | Ubiquitination | EPQEPTNKAPEQQRQ CCCCCCCCCHHHHHC | 27667366 | ||
| 1716 | Ubiquitination | PEQQRQITLKTTPAS HHHHHCEEEEECCCC | 27667366 | ||
| 1718 | Ubiquitination | QQRQITLKTTPASGE HHHCEEEEECCCCCC | 27667366 | ||
| 1719 | Phosphorylation | QRQITLKTTPASGER HHCEEEEECCCCCCC | 22802335 | ||
| 1720 | Phosphorylation | RQITLKTTPASGERG HCEEEEECCCCCCCC | 22802335 | ||
| 1723 | Phosphorylation | TLKTTPASGERGIAS EEEECCCCCCCCCCC | 22802335 | ||
| 1730 | Phosphorylation | SGERGIASTSDPPTA CCCCCCCCCCCCCCC | 25266776 | ||
| 1731 | Phosphorylation | GERGIASTSDPPTAN CCCCCCCCCCCCCCC | 25266776 | ||
| 1732 | Phosphorylation | ERGIASTSDPPTANI CCCCCCCCCCCCCCC | 26643407 | ||
| 1736 | Phosphorylation | ASTSDPPTANIKPTP CCCCCCCCCCCCCCC | 26643407 | ||
| 1742 | Phosphorylation | PTANIKPTPVVSTPS CCCCCCCCCCCCCCC | 25263469 | ||
| 1746 | Phosphorylation | IKPTPVVSTPSKVTA CCCCCCCCCCCHHHH | 26239621 | ||
| 1747 | Phosphorylation | KPTPVVSTPSKVTAA CCCCCCCCCCHHHHH | 22942356 | ||
| 1749 | Phosphorylation | TPVVSTPSKVTAAAM CCCCCCCCHHHHHHH | 24453211 | ||
| 1752 | Phosphorylation | VSTPSKVTAAAMAGN CCCCCHHHHHHHCCC | 22802335 | ||
| 1760 | Acetylation | AAAMAGNKSTPRASI HHHHCCCCCCCCCCC | 23806337 | ||
| 1761 | Phosphorylation | AAMAGNKSTPRASIR HHHCCCCCCCCCCCC | 26745281 | ||
| 1762 | Phosphorylation | AMAGNKSTPRASIRP HHCCCCCCCCCCCCC | 26745281 | ||
| 1780 | Phosphorylation | PATVTNPTTTPTATV CCEECCCCCCCCCEE | 25338131 | ||
| 1963 | Phosphorylation | YNQDSQDSIGEGVTQ CCCCCCCCCCCCCCC | - | ||
| 2080 | Phosphorylation | DAEGGDGTDPGTETE CCCCCCCCCCCCCCC | - | ||
| 2084 | Phosphorylation | GDGTDPGTETEESMG CCCCCCCCCCCCCCC | 20531401 | ||
| 2086 | Phosphorylation | GTDPGTETEESMGGA CCCCCCCCCCCCCCH | - | ||
| 2102 | Phosphorylation | SHQRAADSQNSGEGN HHHHHHHCCCCCCCC | 26239621 | ||
| 2105 | Phosphorylation | RAADSQNSGEGNTSA HHHHCCCCCCCCCHH | 23684622 | ||
| 2110 | Phosphorylation | QNSGEGNTSAAESSF CCCCCCCCHHHHHHH | 26239621 | ||
| 2111 | Phosphorylation | NSGEGNTSAAESSFS CCCCCCCHHHHHHHH | 25293948 | ||
| 2115 | Phosphorylation | GNTSAAESSFSQEVA CCCHHHHHHHHHHHH | 28833060 | ||
| 2116 | Phosphorylation | NTSAAESSFSQEVAR CCHHHHHHHHHHHHH | 28833060 | ||
| 2118 | Phosphorylation | SAAESSFSQEVAREQ HHHHHHHHHHHHHHH | 28833060 | ||
| 2128 | Phosphorylation | VAREQQPTSASERQT HHHHHCCCCHHHCCC | 23684622 | ||
| 2129 | Phosphorylation | AREQQPTSASERQTP HHHHCCCCHHHCCCC | 29514104 | ||
| 2131 | Phosphorylation | EQQPTSASERQTPQA HHCCCCHHHCCCCCC | 23684622 | ||
| 2135 | Phosphorylation | TSASERQTPQAPQSP CCHHHCCCCCCCCCC | 27742792 | ||
| 2141 | Phosphorylation | QTPQAPQSPRRPPHP CCCCCCCCCCCCCCC | 27087446 | ||
| 2174 | Methylation | QRIQMTRRQSVGRGL CEEECCCHHCCCCCC | 24129315 | ||
| 2176 | Phosphorylation | IQMTRRQSVGRGLQL EECCCHHCCCCCCCC | 23737553 | ||
| 2179 | Dimethylation | TRRQSVGRGLQLTPG CCHHCCCCCCCCCCC | - | ||
| 2179 | Methylation | TRRQSVGRGLQLTPG CCHHCCCCCCCCCCC | 24129315 | ||
| 2184 | Phosphorylation | VGRGLQLTPGIGGMQ CCCCCCCCCCCCCCC | 25521595 | ||
| 2201 | Phosphorylation | FFDDEDRTVPSTPTL CCCCCCCCCCCCCEE | 28833060 | ||
| 2204 | Phosphorylation | DEDRTVPSTPTLVVP CCCCCCCCCCEEEEC | 20469934 | ||
| 2205 | Phosphorylation | EDRTVPSTPTLVVPH CCCCCCCCCEEEECC | 26824392 | ||
| 2207 | Phosphorylation | RTVPSTPTLVVPHRT CCCCCCCEEEECCCC | 28833060 | ||
| 2214 | Phosphorylation | TLVVPHRTDGFAEAI EEEECCCCCCHHHHH | 28833060 | ||
| 2223 | Phosphorylation | GFAEAIHSPQVAGVP CHHHHHCCCCCCCCC | 27087446 | ||
| 2231 | Methylation | PQVAGVPRFRFGPPE CCCCCCCCCCCCCCC | 24129315 | ||
| 2398 | Phosphorylation | FRRVRLQTTLRQGVR CCEEHHHHHHHHCCC | 29514104 | ||
| 2411 | Asymmetric dimethylarginine | VRGRQFNRQRGISHA CCCCCHHHHHCCCHH | - | ||
| 2411 | Methylation | VRGRQFNRQRGISHA CCCCCHHHHHCCCHH | 24129315 | ||
| 2413 | Asymmetric dimethylarginine | GRQFNRQRGISHAMG CCCHHHHHCCCHHHC | - | ||
| 2413 | Methylation | GRQFNRQRGISHAMG CCCHHHHHCCCHHHC | 24129315 | ||
| 2422 | Asymmetric dimethylarginine | ISHAMGGRGGINRGN CCHHHCCCCCCCCCC | - | ||
| 2422 | Methylation | ISHAMGGRGGINRGN CCHHHCCCCCCCCCC | 24129315 | ||
| 2427 | Dimethylation | GGRGGINRGNIN--- CCCCCCCCCCCC--- | - | ||
| 2427 | Methylation | GGRGGINRGNIN--- CCCCCCCCCCCC--- | 54541773 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TPR_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TPR_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| AHNK_HUMAN | AHNAK | physical | 20360068 | |
| TRI29_HUMAN | TRIM29 | physical | 20360068 | |
| PPIA_HUMAN | PPIA | physical | 20360068 | |
| TPR_HUMAN | TPR | physical | 20360068 | |
| KPYM_HUMAN | PKM | physical | 20360068 | |
| POF1B_HUMAN | POF1B | physical | 20360068 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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