ARI3B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARI3B_MOUSE
• UniProt AC: Q9Z1N7
• Protein Name: AT-rich interactive domain-containing protein 3B
• Gene Name: Arid3b
• Organism: Mus musculus (Mouse).
• Sequence Length: 568
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor involved in the production of cranial mesenchymal tissues. Favors nuclear targeting of ARID3A..
• Protein Sequence: MEPLQQQQQQQQQKQPQQPLLQMDAREKQGPQTRESQFLYASKLGTQPALLSITPGRPSGSSVLGPLARVPPATPVARMSEQSNVNSEPEEEEGGLEDEDGDDDVAEVAEKEAQAASKYFHMQKVTRQEPRATPMSSLLPVPGLSPQGQQTKEDHTKDASKAPPSVPTAGQPSWSLDEQLKQNGALAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAAAAAAAAAAAAAASAASAGTPALLSSPKIRFSILGLGSSSGTSASSPRIPPASTLRKGDGVPVPVPNRLAVSGTLAGQQAGNRPGPLEHLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGREDRAEPSAPALNLTTSNIGSINMSVDIDGTTYTGVLFAQKPVVHLIAGSTPQSIGSSASSSNSSSSHCSPSPTSSRGTPSAEPSTSWSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEPLQQQQ -------CCHHHHHH	12.35	-
54	Phosphorylation	QPALLSITPGRPSGS CCEEEEECCCCCCCC	19.13	22006019
80	Phosphorylation	ATPVARMSEQSNVNS CCCCHHHHHCCCCCC	27.25	25293948
83	Phosphorylation	VARMSEQSNVNSEPE CHHHHHCCCCCCCCH	38.40	25293948
87	Phosphorylation	SEQSNVNSEPEEEEG HHCCCCCCCCHHHCC	50.69	25293948
137	Phosphorylation	PRATPMSSLLPVPGL CCCCCCHHHCCCCCC	27.89	28285833
145	Phosphorylation	LLPVPGLSPQGQQTK HCCCCCCCCCCCCCC	22.54	25293948
151	Phosphorylation	LSPQGQQTKEDHTKD CCCCCCCCCCCCCCC	28.63	21189417
296	Phosphorylation	LRTQYMKYLYAYECE HHHHHHHHHHHHHHH	6.60	27357545
298	Phosphorylation	TQYMKYLYAYECEKK HHHHHHHHHHHHHHH	12.21	27357545
300	Phosphorylation	YMKYLYAYECEKKAL HHHHHHHHHHHHHHC	13.93	27357545
309	Phosphorylation	CEKKALSSPAELQAA HHHHHCCCHHHHHHH	29.04	-
370	Methylation	LLSSPKIRFSILGLG HHCCCCEEEEEECCC	25.94	24129315
370	Asymmetric dimethylarginine	LLSSPKIRFSILGLG HHCCCCEEEEEECCC	25.94	-
372	Phosphorylation	SSPKIRFSILGLGSS CCCCEEEEEECCCCC	13.68	23737553
378	Phosphorylation	FSILGLGSSSGTSAS EEEECCCCCCCCCCC	26.77	23737553
379	Phosphorylation	SILGLGSSSGTSASS EEECCCCCCCCCCCC	30.87	23737553
380	Phosphorylation	ILGLGSSSGTSASSP EECCCCCCCCCCCCC	48.03	23737553
382	Phosphorylation	GLGSSSGTSASSPRI CCCCCCCCCCCCCCC	24.06	23737553
383	Phosphorylation	LGSSSGTSASSPRIP CCCCCCCCCCCCCCC	29.67	23737553
385	Phosphorylation	SSSGTSASSPRIPPA CCCCCCCCCCCCCCH	40.41	23737553
386	Phosphorylation	SSGTSASSPRIPPAS CCCCCCCCCCCCCHH	20.22	23737553
393	Phosphorylation	SPRIPPASTLRKGDG CCCCCCHHHCCCCCC	33.47	23737553
394	Phosphorylation	PRIPPASTLRKGDGV CCCCCHHHCCCCCCC	32.46	23737553
448	Phosphorylation	EKKASRLSEEEQRLV HHHHHHCCHHHHHHH	41.68	23140645

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARI3B_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARI3B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARI3B_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ARI3B_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.