TCRG1_MOUSE - dbPTM
TCRG1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TCRG1_MOUSE
UniProt AC Q8CGF7
Protein Name Transcription elongation regulator 1
Gene Name Tcerg1
Organism Mus musculus (Mouse).
Sequence Length 1100
Subcellular Localization Nucleus.
Protein Description Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity)..
Protein Sequence MAERGGDGGEGERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPGAPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAVGAPTPTTSSPAPAVSTSTPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPVKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEPIKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20MethylationRFNPGELRMAQQQAL
CCCHHHHHHHHHHHH		17.6818967053
28MethylationMAQQQALRFRGPAPP
HHHHHHHHHCCCCCC		23.4124129315
28Asymmetric dimethylarginineMAQQQALRFRGPAPP
HHHHHHHHHCCCCCC		23.41-
30Asymmetric dimethylarginineQQQALRFRGPAPPPN
HHHHHHHCCCCCCCC		43.69-
30MethylationQQQALRFRGPAPPPN
HHHHHHHCCCCCCCC		43.6924129315
41Asymmetric dimethylargininePPPNAVMRGPPPLMR
CCCCCCCCCCCCCCC		48.11-
41MethylationPPPNAVMRGPPPLMR
CCCCCCCCCCCCCCC		48.1124129315
48Asymmetric dimethylarginineRGPPPLMRPPPPFGM
CCCCCCCCCCCCCCC		48.53-
48MethylationRGPPPLMRPPPPFGM
CCCCCCCCCCCCCCC		48.53-
446UbiquitinationEYKTADGKTYYYNNR
EEECCCCCEEEECCE		33.62-
450PhosphorylationADGKTYYYNNRTLES
CCCCEEEECCEECHH		8.7828576409
483PhosphorylationKEPIKEASEEPLPME
HHHHHHHCCCCCCCC		43.5126643407
605PhosphorylationSIQKWQFSMSAIKEE
HHHHHHHCHHHHHHH		9.2022324799
607PhosphorylationQKWQFSMSAIKEEQE
HHHHHCHHHHHHHHH		26.1622324799
640PhosphorylationDDNKDIDSEKEAAME
CCCCCCCHHHHHHHH		51.4025266776
748PhosphorylationAKFNPRATFSEFAAK
HCCCCCCCHHHHHHH		29.0429176673
750PhosphorylationFNPRATFSEFAAKHA
CCCCCCHHHHHHHHH		27.7029176673
755AcetylationTFSEFAAKHAKDSRF
CHHHHHHHHHHCHHH		40.4422826441
834PhosphorylationPRYKAVDSSSMREDL
CCCCCCCCHHHHHHH		20.0829176673
835PhosphorylationRYKAVDSSSMREDLF
CCCCCCCHHHHHHHH		24.5629176673
836PhosphorylationYKAVDSSSMREDLFK
CCCCCCHHHHHHHHH		26.3025266776
870PhosphorylationRQARIEASLRERERE
HHHHHHHHHHHHHHH		18.3729176673
919PhosphorylationMVRSSDVSWSDTRRT
HHHHCCCCHHHHHHH		26.3430635358
921PhosphorylationRSSDVSWSDTRRTLR
HHCCCCHHHHHHHHH		22.9230635358
923PhosphorylationSDVSWSDTRRTLRKD
CCCCHHHHHHHHHHH		19.2830635358
935PhosphorylationRKDHRWESGSLLERE
HHHCCCCCCCCCCHH		27.0728066266
937PhosphorylationDHRWESGSLLEREEK
HCCCCCCCCCCHHHH		38.7728066266
994UbiquitinationKEDPRCIKFSSSDRK
HHCCCCEECCCCHHH		42.70-
1099PhosphorylationSEPTRRSTK------
CCCCCCCCC------		38.6729514104
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TCRG1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TCRG1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TCRG1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SMN_MOUSESmn1physical
17218272
FMN1_MOUSEFmn1physical
8605874
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TCRG1_MOUSE

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Related Literatures of Post-Translational Modification

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