dbPTM

RFC5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RFC5_MOUSE
UniProt AC	Q9D0F6
Protein Name	Replication factor C subunit 5
Gene Name	Rfc5
Organism	Mus musculus (Mouse).
Sequence Length	339
Subcellular Localization	Nucleus .
Protein Description	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1..
Protein Sequence	MTAAAPSQQRPAAARARNLPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKTDIANILDWMLNQDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MTAAAPSQQRPAAA -CCCCCCCCCCHHHH	33.93	26824392
237	S-nitrosocysteine	TEETVYTCTGHPLKT CEECEEEECCCCCHH	2.05	-
237	S-nitrosylation	TEETVYTCTGHPLKT CEECEEEECCCCCHH	2.05	20925432
259	Phosphorylation	WMLNQDFTTAYKNIM HHHCCCHHHHHHHHH	20.85	-
294	Phosphorylation	VHRVDFPSSVRIHLL HHCCCCCHHHHHHHH	41.27	28066266
295	Phosphorylation	HRVDFPSSVRIHLLT HCCCCCHHHHHHHHH	18.69	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RFC5_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RFC5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RFC5_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RFC5_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RFC5_MOUSE

Related Literatures of Post-Translational Modification