ATX10_MOUSE - dbPTM
ATX10_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ATX10_MOUSE
UniProt AC P28658
Protein Name Ataxin-10
Gene Name Atxn10
Organism Mus musculus (Mouse).
Sequence Length 475
Subcellular Localization Cytoplasm, perinuclear region.
Protein Description Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis..
Protein Sequence MAAPRMPPSRLSGIMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTHAVELACRDPSQVEHLASSLQLITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEESQSIVWVHAFPELFMSCLNHPDKKIVAYCSMILFTSLNAERMKDLEENLNIAINVIEAHQKHPASEWPFLIISDHFLKSPELVEAMYGKLSNQERITLLDIVIAKLVGEEQLTKDDISIFVRHAELIANSFMDQCRNVLKLTSEPHTEDKEALVTIRLLDVLCEMTSNTELLGYLQVFPGLMERVIDVLRVIHEVGKESTNIFSPSDSLKAEGDIEHMTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPLILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDVIAKMEEQGLADASLLKKMGFEIEKSGDKLILKSNNDIPPP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationAAPRMPPSRLSGIMV
CCCCCCHHHCCCCCC		39.7326239621
10MethylationAPRMPPSRLSGIMVP
CCCCCHHHCCCCCCC		38.3524129315
12PhosphorylationRMPPSRLSGIMVPAP
CCCHHHCCCCCCCCC		25.7626824392
34UbiquitinationRALTALFKEQRNRET
HHHHHHHHHHHCCCC		54.5122790023
55UbiquitinationQRVLDILKKSTHAVE
HHHHHHHHHCCCHHH		45.0422790023
237UbiquitinationLVEAMYGKLSNQERI
HHHHHHHCCCCHHHH		31.1122790023
262UbiquitinationVGEEQLTKDDISIFV
HCCHHCCCCHHHHHH		63.0922790023
288UbiquitinationDQCRNVLKLTSEPHT
HHHHHHHHHCCCCCC		45.4922790023
345UbiquitinationRVIHEVGKESTNIFS
HHHHHHCCCCCCCCC		54.3822790023
347PhosphorylationIHEVGKESTNIFSPS
HHHHCCCCCCCCCCC		30.1826643407
348PhosphorylationHEVGKESTNIFSPSD
HHHCCCCCCCCCCCH		33.1626643407
352PhosphorylationKESTNIFSPSDSLKA
CCCCCCCCCCHHCCC		21.5025521595
354PhosphorylationSTNIFSPSDSLKAEG
CCCCCCCCHHCCCCC		38.3426643407
356PhosphorylationNIFSPSDSLKAEGDI
CCCCCCHHCCCCCCH		35.7926643407
358UbiquitinationFSPSDSLKAEGDIEH
CCCCHHCCCCCCHHH		48.6322790023
384UbiquitinationLIGNLCYKNKENQDK
HHHHHHHCCCCCHHH		61.6222790023
386UbiquitinationGNLCYKNKENQDKVN
HHHHHCCCCCHHHHH		54.62-
426PhosphorylationVYAVRNLTEDNSQNQ
HHHHHCCCCCCCCCH		44.8629514104
430PhosphorylationRNLTEDNSQNQDVIA
HCCCCCCCCCHHHHH		42.7128066266
438UbiquitinationQNQDVIAKMEEQGLA
CCHHHHHHHHHCCCC		35.4022790023
448PhosphorylationEQGLADASLLKKMGF
HCCCCCHHHHHHHCC		34.4828066266
451UbiquitinationLADASLLKKMGFEIE
CCCHHHHHHHCCEEE		46.11-
452UbiquitinationADASLLKKMGFEIEK
CCHHHHHHHCCEEEE		44.20-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ATX10_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ATX10_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ATX10_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ATX10_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ATX10_MOUSE

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Related Literatures of Post-Translational Modification

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